REACTOME_SIGNALING_BY_BMP | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | UBE2D3 | Ubiquitin-conjugating enzyme E2 D3 | [1] | -1.11[2] | -0.98[3] | -0.89[4] | -1.97[5] | -1.52[6] | -1.19[7] |
2 | FSTL1 | Follistatin-related protein 1 | [8] | -6.61[9] | -7.00[10] | -5.73[11] | 2.42[12] | 2.33[13] | 0.50[14] |
3 | BMP2 | Bone morphogenetic protein 2 | [15] | -5.27[16] | -8.58[17] | 0.37[18] | -3.11[19] | -2.90[20] | -3.23[21] |
4 | SMAD1 | Mothers against decapentaplegic homolog 1 | [22] | -1.34[23] | -1.27[24] | -1.12[25] | -1.96[26] | -1.43[27] | -0.42[28] |
5 | SMAD7 | Mothers against decapentaplegic homolog 7 | [29] | 1.57[30] | -0.50[31] | -1.66[32] | -0.64[33] | -0.97[34] | -1.05[35] |
6 | SMURF1 | E3 ubiquitin-protein ligase SMURF1 | [36] | 1.15[37] | 0.41[38] | 1.18[39] | -0.02[40] | -0.15[41] | 0.34[42] |
7 | SKI | Ski oncogene | [43] | 2.18[44] | 1.70[45] | 1.02[46] | 0.94[47] | 1.25[48] | -0.02[49] |
8 | SMAD4 | Mothers against decapentaplegic homolog 4 | [50] | 1.11[51] | 1.55[52] | 1.37[53] | 0.68[54] | 1.02[55] | 1.74[56] |
9 | SMAD5 | Mothers against decapentaplegic homolog 5 | [57] | 1.54[58] | 2.05[59] | 1.69[60] | 1.42[61] | 1.43[62] | 1.90[63] |
10 | BMPR1A | Bone morphogenetic protein receptor type-1A | [64] | 1.02[65] | 1.47[66] | -0.01[67] | 0.02[68] | 0.26[69] | 0.13[70] |
11 | UBE2D1 | Ubiquitin-conjugating enzyme E2 D1 | [71] | 0.51[72] | 1.19[73] | 1.38[74] | 0.29[75] | 0.03[76] | -0.55[77] |
12 | ZFYVE16 | Zinc finger FYVE domain-containing protein 16 | [78] | 0.45[79] | 2.01[80] | 1.78[81] | 1.37[82] | 0.96[83] | 1.58[84] |
13 | GREM2 | Gremlin-2 | [85] | -11.35[86] | -10.05[87] | -2.25[88] | -1.55[89] | -6.68[90] | 0.99[91] |
14 | SMURF2 | E3 ubiquitin-protein ligase SMURF2 | [92] | 1.43[93] | 1.27[94] | -0.37[95] | -0.04[96] | 0.38[97] | -0.91[98] |
15 | SMAD6 | Mothers against decapentaplegic homolog 6 | [99] | 1.12[100] | -0.80[101] | -0.53[102] | 0.22[103] | -1.36[104] | -0.19[105] |
16 | BMPR2 | Bone morphogenetic protein receptor type-2 | [106] | 2.90[107] | 1.74[108] | 2.27[109] | 2.91[110] | 2.21[111] | 3.25[112] |
17 | ACVR2A | Activin receptor type-2A | [113] | 0.56[114] | 1.39[115] | 1.08[116] | -0.41[117] | 0.07[118] | 1.63[119] |
18 | ACVR2B | Activin receptor type-2B | [120] | 1.99[121] | 3.20[122] | 3.88[123] | -0.13[124] | -0.36[125] | 2.12[126] |
19 | ACVRL1 | Serine/threonine-protein kinase receptor R3 | [127] | -4.39[128] | -4.96[129] | -4.18[130] | -3.44[131] | -3.17[132] | 1.96[133] |
20 | SMAD9 | Mothers against decapentaplegic homolog 9 | [134] | 3.69[135] | 3.20[136] | 2.32[137] | 0.97[138] | 2.45[139] | 1.83[140] |
21 | AMHR2 | Anti-Muellerian hormone type-2 receptor | [141] | 1.66[142] | -0.05[143] | -1.92[144] | -4.73[145] | -3.96[146] | 0.93[147] |
22 | AMH | Muellerian-inhibiting factor | [148] | -1.41[149] | 2.93[150] | 5.55[151] | 0.65[152] | 3.94[153] | 0.46[154] |
23 | BMP10 | Bone morphogenetic protein 10 | [155] | [156] | [157] | [158] | -4.27[159] | [160] | 6.75[161] |
24 | BMPR1B | Bone morphogenetic protein receptor type-1B | [162] | -1.30[163] | -2.32[164] | 3.18[165] | 4.55[166] | 1.16[167] | 5.51[168] |
25 | GDF2 | Growth/differentiation factor 2 | [169] | [170] | [171] | [172] | [173] | [174] | 8.48[175] |
26 | CHRDL1 | Chordin-like protein 1 | [176] | -0.74[177] | 0.65[178] | [179] | 7.53[180] | -0.48[181] | 5.03[182] |
27 | CER1 | Cerberus | [183] | [184] | [185] | [186] | [187] | [188] | [189] |
28 | NOG | Noggin | [190] | [191] | [192] | [193] | [194] | [195] | [196] |