REACTOME_SHC_RELATED_EVENTS_TRIGGERED_BY_IGF1R Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 IGF2 Insulin-like growth factor II [1] -2.64[2] -0.96[3] -3.49[4] -13.57[5] -11.22[6] -6.39[7]
2 GRB2 Growth factor receptor-bound protein 2 [8] 1.52[9] 0.94[10] 1.30[11] 0.40[12] 0.78[13] 0.92[14]
3 IGF1 Insulin-like growth factor I [15] -8.10[16] -9.45[17] -7.42[18] -1.69[19] -9.06[20] 1.54[21]
4 SHC1 SHC-transforming protein 1 [22] 1.49[23] 1.29[24] 1.61[25] 2.50[26] 2.45[27] 1.40[28]
5 NRAS GTPase NRas [29] 0.95[30] 0.97[31] 1.62[32] 0.85[33] 0.88[34] 0.37[35]
6 HRAS GTPase HRas [36] -0.68[37] -1.81[38] -2.36[39] -1.10[40] -0.85[41] -2.04[42]
7 KRAS GTPase KRas [43] -0.19[44] -0.63[45] 1.21[46] 0.65[47] 0.77[48] 1.30[49]
8 SOS1 Son of sevenless homolog 1 [50] 0.22[51] 1.33[52] 1.09[53] 0.70[54] 0.39[55] 1.16[56]
9 IGF1R Insulin-like growth factor 1 receptor [57] 5.07[58] 3.96[59] 2.87[60] 4.32[61] 4.33[62] 2.71[63]
[1]
ref_hepatocyte IGF2
Mean 101
Standard deviation 71
Values 1.4e+02 2.1 86 82 1.9e+02
[2]
HepG2 IGF2
Mean 28.5
Standard deviation 20
Values 42 15
[3]
HepG2.C3A IGF2
Mean 109
Standard deviation 33
Values 1.3e+02 86
[4]
HuH.7 IGF2
Mean 15.2
Standard deviation 9
Values 15 24 6.2
[5]
SNU475 IGF2
Mean 0.0169
Standard deviation 0.0024
Values 0.019 0.015
[6]
THLE IGF2
Mean 0.0701
Standard deviation 0.0013
Values 0.071 0.069
[7]
liver IGF2
Mean 1.11
Standard deviation 0.93
Values 2 0.19 1.9 0.42
[8]
ref_hepatocyte GRB2
Mean 20.7
Standard deviation 5.5
Values 27 26 20 14 17
[9]
HepG2 GRB2
Mean 104
Standard deviation 4.7
Values 1e+02 1.1e+02
[10]
HepG2.C3A GRB2
Mean 83.1
Standard deviation 0.44
Values 83 83
[11]
HuH.7 GRB2
Mean 86.7
Standard deviation 7.6
Values 89 78 93
[12]
SNU475 GRB2
Mean 55.7
Standard deviation 1.4
Values 55 57
[13]
THLE GRB2
Mean 58.8
Standard deviation 3.7
Values 56 61
[14]
liver GRB2
Mean 36.1
Standard deviation 16
Values 50 22 50 22
[15]
ref_hepatocyte IGF1
Mean 17.2
Standard deviation 16
Values 0 18 5 24 39
[16]
HepG2 IGF1
Mean 0.111
Standard deviation 0.0052
Values 0.11 0.11
[17]
HepG2.C3A IGF1
Mean 0.0516
Standard deviation 0.018
Values 0.039 0.064
[18]
HuH.7 IGF1
Mean 0.171
Standard deviation 0.058
Values 0.11 0.22 0.19
[19]
SNU475 IGF1
Mean 10.9
Standard deviation 5.6
Values 15 6.9
[20]
THLE IGF1
Mean 0.0535
Standard deviation 0.008
Values 0.059 0.048
[21]
liver IGF1
Mean 46.3
Standard deviation 31
Values 92 24 31 39
[22]
ref_hepatocyte SHC1
Mean 16.6
Standard deviation 7.2
Values 5.8 17 19 26 16
[23]
HepG2 SHC1
Mean 82
Standard deviation 0.099
Values 82 82
[24]
HepG2.C3A SHC1
Mean 84.9
Standard deviation 11
Values 77 93
[25]
HuH.7 SHC1
Mean 85.9
Standard deviation 2.4
Values 89 84 85
[26]
SNU475 SHC1
Mean 191
Standard deviation 36
Values 2.2e+02 1.7e+02
[27]
THLE SHC1
Mean 150
Standard deviation 11
Values 1.4e+02 1.6e+02
[28]
liver SHC1
Mean 40.4
Standard deviation 11
Values 37 32 56 37
[29]
ref_hepatocyte NRAS
Mean 14.4
Standard deviation 13
Values 32 23 9.3 3.3 4.6
[30]
HepG2 NRAS
Mean 49.3
Standard deviation 10
Values 42 57
[31]
HepG2.C3A NRAS
Mean 59.2
Standard deviation 18
Values 47 72
[32]
HuH.7 NRAS
Mean 75.6
Standard deviation 9.1
Values 86 70 71
[33]
SNU475 NRAS
Mean 52.9
Standard deviation 9.2
Values 59 46
[34]
THLE NRAS
Mean 44
Standard deviation 8.9
Values 38 50
[35]
liver NRAS
Mean 17.2
Standard deviation 2.6
Values 14 21 18 16
[36]
ref_hepatocyte HRAS
Mean 11.6
Standard deviation 9
Values 4 27 11 7.4 8.8
[37]
HepG2 HRAS
Mean 12.7
Standard deviation 1.1
Values 14 12
[38]
HepG2.C3A HRAS
Mean 6.96
Standard deviation 1.3
Values 6 7.9
[39]
HuH.7 HRAS
Mean 3.85
Standard deviation 1.6
Values 3.6 2.4 5.6
[40]
SNU475 HRAS
Mean 11
Standard deviation 0.62
Values 11 11
[41]
THLE HRAS
Mean 10.7
Standard deviation 2.3
Values 9.1 12
[42]
liver HRAS
Mean 2.6
Standard deviation 1.6
Values 4.1 1.1 3.8 1.4
[43]
ref_hepatocyte KRAS
Mean 8.97
Standard deviation 7.9
Values 18 17 5.4 1.7 2.7
[44]
HepG2 KRAS
Mean 13.9
Standard deviation 3.1
Values 12 16
[45]
HepG2.C3A KRAS
Mean 12.2
Standard deviation 2.3
Values 11 14
[46]
HuH.7 KRAS
Mean 35.4
Standard deviation 4.8
Values 40 30 36
[47]
SNU475 KRAS
Mean 28.7
Standard deviation 5.5
Values 33 25
[48]
THLE KRAS
Mean 25.4
Standard deviation 1.5
Values 24 26
[49]
liver KRAS
Mean 20.4
Standard deviation 8.7
Values 33 16 19 14
[50]
ref_hepatocyte SOS1
Mean 6.81
Standard deviation 11
Values 27 1.9 2.2 1.3 1.5
[51]
HepG2 SOS1
Mean 14
Standard deviation 6.5
Values 9.4 19
[52]
HepG2.C3A SOS1
Mean 36.1
Standard deviation 3.7
Values 39 33
[53]
HuH.7 SOS1
Mean 24.6
Standard deviation 11
Values 22 37 15
[54]
SNU475 SOS1
Mean 22.5
Standard deviation 3.3
Values 25 20
[55]
THLE SOS1
Mean 14.8
Standard deviation 1.4
Values 16 14
[56]
liver SOS1
Mean 14.1
Standard deviation 3.8
Values 13 18 9.3 16
[57]
ref_hepatocyte IGF1R
Mean 0.745
Standard deviation 1.4
Values 3.3 0.021 0.29 0.043 0.065
[58]
HepG2 IGF1R
Mean 44
Standard deviation 16
Values 55 33
[59]
HepG2.C3A IGF1R
Mean 24.3
Standard deviation 6.5
Values 29 20
[60]
HuH.7 IGF1R
Mean 9.29
Standard deviation 2.1
Values 12 7.5 8.8
[61]
SNU475 IGF1R
Mean 30.3
Standard deviation 1.7
Values 32 29
[62]
THLE IGF1R
Mean 24.8
Standard deviation 4.5
Values 22 28
[63]
liver IGF1R
Mean 4.51
Standard deviation 2.6
Values 2.4 5.8 2.2 7.6