REACTOME_SEROTONIN_AND_MELATONIN_BIOSYNTHESIS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 DDC Aromatic-L-amino-acid decarboxylase [1] 0.04[2] 0.03[3] 0.05[4] -0.40[5] -1.02[6] 0.05[7]
2 ASMT Acetylserotonin O-methyltransferase [8] [9] [10] [11] [12] [13] [14]
3 AANAT Serotonin N-acetyltransferase [15] 1.47[16] 2.80[17] 1.46[18] 8.17[19] 8.08[20] 1.02[21]
4 TPH1 Tryptophan 5-hydroxylase 1 [22] [23] [24] [25] [26] [27] [28]
5 TPH2 Tryptophan 5-hydroxylase 2 [29] [30] [31] [32] [33] [34] [35]
[1]
ref_hepatocyte DDC
Mean 16.2
Standard deviation 7.9
Values 20 15 3.1 19 24
[2]
HepG2 DDC
Mean 8.45
Standard deviation 3.2
Values 6.2 11
[3]
HepG2.C3A DDC
Mean 17.3
Standard deviation 4.6
Values 14 21
[4]
HuH.7 DDC
Mean 43.9
Standard deviation 9.4
Values 45 34 53
[5]
SNU475 DDC
Mean 0.201
Standard deviation 0.063
Values 0.25 0.16
[6]
THLE DDC
Mean 0.11
Standard deviation 0.087
Values 0.17 0.048
[7]
liver DDC
Mean 25.7
Standard deviation 11
Values 41 15 19 28
[8]
ref_hepatocyte ASMT
Mean 0.657
Standard deviation 0.74
Values 0.29 0.27 0 1.8 0.88
[9]
HepG2 ASMT
Missing
[10]
HepG2.C3A ASMT
Missing
[11]
HuH.7 ASMT
Missing
[12]
SNU475 ASMT
Missing
[13]
THLE ASMT
Missing
[14]
liver ASMT
Missing
[15]
ref_hepatocyte AANAT
Mean 0.00813
Standard deviation 0.018
Values 0 0 0 0 0.041
[16]
HepG2 AANAT
Mean 0.0115
Standard deviation 0.016
Values 0.023 0
[17]
HepG2.C3A AANAT
Mean 0.0593
Standard deviation 0.054
Values 0.097 0.021
[18]
HuH.7 AANAT
Mean 0.0585
Standard deviation 0.03
Values 0.066 0.026 0.084
[19]
SNU475 AANAT
Mean 0.0386
Standard deviation 0.0044
Values 0.042 0.035
[20]
THLE AANAT
Mean 0.0305
Standard deviation 0.0096
Values 0.024 0.037
[21]
liver AANAT
Mean 0.0253
Standard deviation 0.021
Values 0.024 0 0.051 0.026
[22]
ref_hepatocyte TPH1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[23]
HepG2 TPH1
Mean 0.0701
Standard deviation 0.01
Values 0.063 0.077
[24]
HepG2.C3A TPH1
Mean 0.269
Standard deviation 0.11
Values 0.19 0.34
[25]
HuH.7 TPH1
Mean 0.0367
Standard deviation 0.025
Values 0.066 0.026 0.019
[26]
SNU475 TPH1
Mean 0.0361
Standard deviation 0.008
Values 0.042 0.03
[27]
THLE TPH1
Mean 0.0911
Standard deviation 0.039
Values 0.12 0.064
[28]
liver TPH1
Mean 0.0508
Standard deviation 0.037
Values 0 0.086 0.051 0.066
[29]
ref_hepatocyte TPH2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[30]
HepG2 TPH2
Mean 0
Standard deviation 0
Values 0 0
[31]
HepG2.C3A TPH2
Mean 0
Standard deviation 0
Values 0 0
[32]
HuH.7 TPH2
Mean 0.00642
Standard deviation 0.011
Values 0 0.019 0
[33]
SNU475 TPH2
Mean 0
Standard deviation 0
Values 0 0
[34]
THLE TPH2
Mean 0
Standard deviation 0
Values 0 0
[35]
liver TPH2
Mean 0.00357
Standard deviation 0.0071
Values 0 0.014 0 0