REACTOME_SENSING_OF_DNA_DOUBLE_STRAND_BREAKS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 KPNA2 Importin subunit alpha-1 [1] 0.18[2] -0.49[3] -0.02[4] -0.40[5] 0.06[6] -2.44[7]
2 KAT5 Histone acetyltransferase KAT5 [8] -1.38[9] -1.51[10] -2.60[11] -1.76[12] -2.12[13] -1.72[14]
3 NBN Nibrin [15] -1.02[16] -0.38[17] -0.68[18] 0.58[19] -0.58[20] 0.62[21]
4 RAD50 DNA repair protein RAD50 [22] -0.45[23] 1.14[24] 0.24[25] 0.34[26] 0.56[27] 1.55[28]
5 ATM Serine-protein kinase ATM [29] 2.43[30] 3.49[31] 3.16[32] 3.23[33] 2.44[34] 4.34[35]
6 MRE11 Double-strand break repair protein MRE11 [36] [37] [38] [39] [40] [41] [42]
[1]
ref_hepatocyte KPNA2
Mean 30
Standard deviation 20
Values 52 43 38 12 5.9
[2]
HepG2 KPNA2
Mean 114
Standard deviation 30
Values 93 1.4e+02
[3]
HepG2.C3A KPNA2
Mean 92.8
Standard deviation 31
Values 71 1.1e+02
[4]
HuH.7 KPNA2
Mean 129
Standard deviation 39
Values 1.6e+02 85 1.4e+02
[5]
SNU475 KPNA2
Mean 79.5
Standard deviation 2.2
Values 78 81
[6]
THLE KPNA2
Mean 148
Standard deviation 45
Values 1.2e+02 1.8e+02
[7]
liver KPNA2
Mean 12.3
Standard deviation 7.9
Values 15 8.4 22 4
[8]
ref_hepatocyte KAT5
Mean 6.92
Standard deviation 2.7
Values 6 6.4 12 6.3 4.4
[9]
HepG2 KAT5
Mean 8.9
Standard deviation 0.12
Values 9 8.8
[10]
HepG2.C3A KAT5
Mean 10.6
Standard deviation 0.63
Values 11 10
[11]
HuH.7 KAT5
Mean 4.96
Standard deviation 0.22
Values 4.9 4.8 5.2
[12]
SNU475 KAT5
Mean 7.11
Standard deviation 0.33
Values 6.9 7.3
[13]
THLE KAT5
Mean 7.53
Standard deviation 0.42
Values 7.2 7.8
[14]
liver KAT5
Mean 4.69
Standard deviation 1
Values 5.5 4.1 5.7 3.5
[15]
ref_hepatocyte NBN
Mean 5.99
Standard deviation 3.6
Values 7.6 11 3.9 2.7 4.3
[16]
HepG2 NBN
Mean 9.9
Standard deviation 6.3
Values 5.4 14
[17]
HepG2.C3A NBN
Mean 20
Standard deviation 9.1
Values 14 26
[18]
HuH.7 NBN
Mean 16.2
Standard deviation 4.2
Values 20 12 17
[19]
SNU475 NBN
Mean 31.2
Standard deviation 0.96
Values 30 32
[20]
THLE NBN
Mean 19
Standard deviation 0.88
Values 20 18
[21]
liver NBN
Mean 20.5
Standard deviation 4.2
Values 19 24 24 16
[22]
ref_hepatocyte RAD50
Mean 3.85
Standard deviation 2.1
Values 3.9 7.4 2.3 2.9 2.8
[23]
HepG2 RAD50
Mean 9.45
Standard deviation 2.3
Values 7.9 11
[24]
HepG2.C3A RAD50
Mean 36.9
Standard deviation 0.99
Values 38 36
[25]
HuH.7 RAD50
Mean 19.7
Standard deviation 4.1
Values 22 22 15
[26]
SNU475 RAD50
Mean 17
Standard deviation 2.2
Values 15 19
[27]
THLE RAD50
Mean 26.8
Standard deviation 8.4
Values 33 21
[28]
liver RAD50
Mean 25.2
Standard deviation 5.7
Values 32 26 25 18
[29]
ref_hepatocyte ATM
Mean 0.969
Standard deviation 0.7
Values 2.1 0.69 0.27 0.7 1.1
[30]
HepG2 ATM
Mean 17.5
Standard deviation 8.3
Values 12 23
[31]
HepG2.C3A ATM
Mean 47.4
Standard deviation 4.5
Values 44 51
[32]
HuH.7 ATM
Mean 37.5
Standard deviation 9.1
Values 41 44 27
[33]
SNU475 ATM
Mean 31.7
Standard deviation 8.2
Values 38 26
[34]
THLE ATM
Mean 24.9
Standard deviation 4.4
Values 28 22
[35]
liver ATM
Mean 43.7
Standard deviation 31
Values 17 76 17 64
[36]
ref_hepatocyte MRE11
Missing
[37]
HepG2 MRE11
Missing
[38]
HepG2.C3A MRE11
Missing
[39]
HuH.7 MRE11
Missing
[40]
SNU475 MRE11
Missing
[41]
THLE MRE11
Missing
[42]
liver MRE11
Missing