REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 MYL6 Myosin light polypeptide 6 [1] -2.01[2] -1.51[3] -2.49[4] -1.53[5] -1.44[6] -2.28[7]
2 MYL12B Myosin regulatory light chain 12B [8] -0.75[9] -0.31[10] -0.17[11] -0.60[12] -0.86[13] -1.05[14]
3 RHOA Transforming protein RhoA [15] 0.32[16] 0.14[17] 0.54[18] -0.31[19] 0.59[20] 0.02[21]
4 RHOC Rho-related GTP-binding protein RhoC [22] -0.31[23] -0.40[24] -0.65[25] -0.10[26] 0.22[27] -1.35[28]
5 RHOB Rho-related GTP-binding protein RhoB [29] 0.47[30] 0.21[31] -1.75[32] -1.38[33] -1.79[34] 1.22[35]
6 MYH9 Myosin-9 [36] 2.68[37] 1.44[38] 1.58[39] 2.13[40] 2.46[41] 1.73[42]
7 RAC1 Ras-related C3 botulinum toxin substrate 1 [43] 0.87[44] 0.86[45] 1.74[46] 0.93[47] 1.35[48] 0.38[49]
8 RND1 Rho-related GTP-binding protein Rho6 [50] -3.99[51] -3.29[52] -2.09[53] -5.54[54] -4.73[55] -2.09[56]
9 RRAS Ras-related protein R-Ras [57] -0.23[58] -0.89[59] -0.14[60] 0.63[61] 1.08[62] -0.84[63]
10 MET Hepatocyte growth factor receptor [64] 1.35[65] 1.69[66] 2.50[67] 2.45[68] 1.61[69] 2.31[70]
11 ROCK1 Rho-associated protein kinase 1 [71] 0.31[72] 2.15[73] 3.10[74] 2.27[75] 2.06[76] 2.92[77]
12 ERBB2 Receptor tyrosine-protein kinase erbB-2 [78] 3.63[79] 2.77[80] 4.12[81] 2.17[82] 2.22[83] 1.50[84]
13 ARHGEF12 Rho guanine nucleotide exchange factor 12 [85] 3.28[86] 3.36[87] 3.17[88] 3.91[89] 3.51[90] 5.51[91]
14 MYH14 Myosin-14 [92] 2.14[93] 2.57[94] 2.72[95] 1.41[96] -1.58[97] 2.59[98]
15 MYH10 Myosin-10 [99] 3.59[100] 3.93[101] 4.66[102] 3.38[103] 3.71[104] 3.40[105]
16 PLXNB1 Plexin-B1 [106] 3.54[107] 4.75[108] 4.46[109] -0.77[110] 1.78[111] 4.59[112]
17 ROCK2 Rho-associated protein kinase 2 [113] 2.74[114] 4.29[115] 2.94[116] 3.55[117] 1.76[118] 3.27[119]
18 MYL9 Myosin regulatory light polypeptide 9 [120] 2.32[121] 2.44[122] -0.07[123] 5.50[124] 3.39[125] 1.26[126]
19 ARHGAP35 Rho GTPase-activating protein 35 [127] 3.61[128] 4.05[129] 4.77[130] 3.65[131] 3.67[132] 4.60[133]
20 LIMK2 LIM domain kinase 2 [134] 2.76[135] 3.45[136] 3.78[137] 1.28[138] 2.37[139] 2.62[140]
21 LIMK1 LIM domain kinase 1 [141] 3.56[142] 2.77[143] 2.53[144] 4.42[145] 3.10[146] -0.15[147]
22 ARHGEF11 Rho guanine nucleotide exchange factor 11 [148] 3.30[149] 3.73[150] 3.60[151] 4.18[152] 3.92[153] 3.93[154]
23 SEMA4D Semaphorin-4D [155] 0.86[156] 1.94[157] 3.25[158] 0.80[159] 3.66[160] 3.45[161]
24 MYH11 Myosin-11 [162] 4.63[163] 4.57[164] 5.03[165] 4.59[166] 4.17[167] 11.30[168]
[1]
ref_hepatocyte MYL6
Mean 1.19e+03
Standard deviation 1.2e+03
Values 9.4e+02 3.2e+03 7.6e+02 5.1e+02 5.1e+02
[2]
HepG2 MYL6
Mean 272
Standard deviation 59
Values 2.3e+02 3.1e+02
[3]
HepG2.C3A MYL6
Mean 275
Standard deviation 92
Values 2.1e+02 3.4e+02
[4]
HuH.7 MYL6
Mean 118
Standard deviation 30
Values 1.1e+02 94 1.5e+02
[5]
SNU475 MYL6
Mean 403
Standard deviation 1.9e+02
Values 5.4e+02 2.7e+02
[6]
THLE MYL6
Mean 354
Standard deviation 52
Values 3.2e+02 3.9e+02
[7]
liver MYL6
Mean 138
Standard deviation 1.3e+02
Values 2.6e+02 37 2.3e+02 21
[8]
ref_hepatocyte MYL12B
Mean 317
Standard deviation 2e+02
Values 2e+02 6.8e+02 2.5e+02 2.4e+02 2.1e+02
[9]
HepG2 MYL12B
Mean 174
Standard deviation 36
Values 1.5e+02 2e+02
[10]
HepG2.C3A MYL12B
Mean 168
Standard deviation 40
Values 1.4e+02 2e+02
[11]
HuH.7 MYL12B
Mean 158
Standard deviation 19
Values 1.5e+02 1.4e+02 1.8e+02
[12]
SNU475 MYL12B
Mean 204
Standard deviation 67
Values 2.5e+02 1.6e+02
[13]
THLE MYL12B
Mean 140
Standard deviation 22
Values 1.2e+02 1.6e+02
[14]
liver MYL12B
Mean 85.6
Standard deviation 68
Values 1.5e+02 34 1.4e+02 20
[15]
ref_hepatocyte RHOA
Mean 177
Standard deviation 1.2e+02
Values 2.2e+02 3.8e+02 1.4e+02 75 79
[16]
HepG2 RHOA
Mean 204
Standard deviation 38
Values 2.3e+02 1.8e+02
[17]
HepG2.C3A RHOA
Mean 129
Standard deviation 1.6
Values 1.3e+02 1.3e+02
[18]
HuH.7 RHOA
Mean 144
Standard deviation 23
Values 1.6e+02 1.2e+02 1.6e+02
[19]
SNU475 RHOA
Mean 139
Standard deviation 21
Values 1.5e+02 1.2e+02
[20]
THLE RHOA
Mean 214
Standard deviation 38
Values 1.9e+02 2.4e+02
[21]
liver RHOA
Mean 101
Standard deviation 59
Values 1.6e+02 54 1.4e+02 46
[22]
ref_hepatocyte RHOC
Mean 128
Standard deviation 1.2e+02
Values 28 2.1e+02 3.1e+02 56 39
[23]
HepG2 RHOC
Mean 95.1
Standard deviation 9.4
Values 1e+02 88
[24]
HepG2.C3A RHOC
Mean 64.3
Standard deviation 2.3
Values 66 63
[25]
HuH.7 RHOC
Mean 45.7
Standard deviation 7.4
Values 39 53 45
[26]
SNU475 RHOC
Mean 117
Standard deviation 12
Values 1.3e+02 1.1e+02
[27]
THLE RHOC
Mean 120
Standard deviation 7.4
Values 1.1e+02 1.3e+02
[28]
liver RHOC
Mean 28.1
Standard deviation 21
Values 52 13 38 9.2
[29]
ref_hepatocyte RHOB
Mean 121
Standard deviation 74
Values 81 64 88 2.5e+02 1.3e+02
[30]
HepG2 RHOB
Mean 154
Standard deviation 31
Values 1.8e+02 1.3e+02
[31]
HepG2.C3A RHOB
Mean 92.7
Standard deviation 27
Values 1.1e+02 74
[32]
HuH.7 RHOB
Mean 20.2
Standard deviation 3.4
Values 17 24 20
[33]
SNU475 RHOB
Mean 45.5
Standard deviation 23
Values 61 30
[34]
THLE RHOB
Mean 28.2
Standard deviation 1.3
Values 27 29
[35]
liver RHOB
Mean 158
Standard deviation 87
Values 1.3e+02 1.5e+02 71 2.8e+02
[36]
ref_hepatocyte MYH9
Mean 89.9
Standard deviation 85
Values 42 2e+02 1.7e+02 21 22
[37]
HepG2 MYH9
Mean 531
Standard deviation 80
Values 5.9e+02 4.7e+02
[38]
HepG2.C3A MYH9
Mean 161
Standard deviation 42
Values 1.9e+02 1.3e+02
[39]
HuH.7 MYH9
Mean 151
Standard deviation 45
Values 2e+02 1.3e+02 1.2e+02
[40]
SNU475 MYH9
Mean 384
Standard deviation 1.4e+02
Values 4.8e+02 2.9e+02
[41]
THLE MYH9
Mean 399
Standard deviation 1.2e+02
Values 3.1e+02 4.9e+02
[42]
liver MYH9
Mean 167
Standard deviation 46
Values 1.1e+02 2e+02 1.5e+02 2.1e+02
[43]
ref_hepatocyte RAC1
Mean 52
Standard deviation 20
Values 28 59 81 45 47
[44]
HepG2 RAC1
Mean 87.4
Standard deviation 1.9
Values 89 86
[45]
HepG2.C3A RAC1
Mean 62
Standard deviation 7.4
Values 67 57
[46]
HuH.7 RAC1
Mean 97.2
Standard deviation 9.7
Values 1e+02 86 1e+02
[47]
SNU475 RAC1
Mean 96.5
Standard deviation 10
Values 89 1e+02
[48]
THLE RAC1
Mean 107
Standard deviation 19
Values 94 1.2e+02
[49]
liver RAC1
Mean 37.8
Standard deviation 32
Values 63 12 67 9.5
[50]
ref_hepatocyte RND1
Mean 26.9
Standard deviation 39
Values 0.28 4 94 26 9.9
[51]
HepG2 RND1
Mean 1.56
Standard deviation 0.15
Values 1.5 1.7
[52]
HepG2.C3A RND1
Mean 1.81
Standard deviation 0.44
Values 2.1 1.5
[53]
HuH.7 RND1
Mean 3.55
Standard deviation 0.96
Values 2.5 3.9 4.3
[54]
SNU475 RND1
Mean 0.562
Standard deviation 0.37
Values 0.82 0.3
[55]
THLE RND1
Mean 0.817
Standard deviation 0.2
Values 0.96 0.68
[56]
liver RND1
Mean 3.54
Standard deviation 0.89
Values 3.4 3.3 4.8 2.7
[57]
ref_hepatocyte RRAS
Mean 13
Standard deviation 11
Values 2.5 30 16 8.2 7.6
[58]
HepG2 RRAS
Mean 10.3
Standard deviation 5.7
Values 14 6.2
[59]
HepG2.C3A RRAS
Mean 4.63
Standard deviation 1.6
Values 5.8 3.5
[60]
HuH.7 RRAS
Mean 6.62
Standard deviation 0.43
Values 6.6 6.2 7.1
[61]
SNU475 RRAS
Mean 19.7
Standard deviation 4
Values 22 17
[62]
THLE RRAS
Mean 22.2
Standard deviation 0.93
Values 23 22
[63]
liver RRAS
Mean 4.07
Standard deviation 3.5
Values 7.4 0.8 6.8 1.3
[64]
ref_hepatocyte MET
Mean 12.9
Standard deviation 12
Values 6.9 32 16 3.7 5.7
[65]
HepG2 MET
Mean 30.2
Standard deviation 2.7
Values 32 28
[66]
HepG2.C3A MET
Mean 27.5
Standard deviation 6.5
Values 23 32
[67]
HuH.7 MET
Mean 40.8
Standard deviation 7.3
Values 43 47 33
[68]
SNU475 MET
Mean 68.7
Standard deviation 7.1
Values 64 74
[69]
THLE MET
Mean 31.7
Standard deviation 2
Values 33 30
[70]
liver MET
Mean 35.9
Standard deviation 13
Values 27 46 22 48
[71]
ref_hepatocyte ROCK1
Mean 6.73
Standard deviation 4.9
Values 9.7 14 3.6 2.5 3.9
[72]
HepG2 ROCK1
Mean 7.68
Standard deviation 2.4
Values 6 9.4
[73]
HepG2.C3A ROCK1
Mean 19.7
Standard deviation 1.6
Values 19 21
[74]
HuH.7 ROCK1
Mean 32.3
Standard deviation 9
Values 36 39 22
[75]
SNU475 ROCK1
Mean 31.8
Standard deviation 1.6
Values 31 33
[76]
THLE ROCK1
Mean 22.6
Standard deviation 6.2
Values 27 18
[77]
liver ROCK1
Mean 28.7
Standard deviation 3.4
Values 30 32 25 27
[78]
ref_hepatocyte ERBB2
Mean 6.44
Standard deviation 3.8
Values 13 3.9 4.7 3.7 7.1
[79]
HepG2 ERBB2
Mean 73.6
Standard deviation 10
Values 66 81
[80]
HepG2.C3A ERBB2
Mean 29
Standard deviation 6.9
Values 34 24
[81]
HuH.7 ERBB2
Mean 62.5
Standard deviation 7.1
Values 69 55 63
[82]
SNU475 ERBB2
Mean 28.2
Standard deviation 8.4
Values 34 22
[83]
THLE ERBB2
Mean 24.1
Standard deviation 2.7
Values 22 26
[84]
liver ERBB2
Mean 10.2
Standard deviation 3.4
Values 7.9 8.1 9.6 15
[85]
ref_hepatocyte ARHGEF12
Mean 6.33
Standard deviation 3.3
Values 5.1 6.1 2.5 6.3 12
[86]
HepG2 ARHGEF12
Mean 56.4
Standard deviation 18
Values 44 69
[87]
HepG2.C3A ARHGEF12
Mean 42.7
Standard deviation 1.7
Values 42 44
[88]
HuH.7 ARHGEF12
Mean 31.9
Standard deviation 7.3
Values 37 36 23
[89]
SNU475 ARHGEF12
Mean 92.7
Standard deviation 12
Values 1e+02 84
[90]
THLE ARHGEF12
Mean 58.1
Standard deviation 5.9
Values 54 62
[91]
liver ARHGEF12
Mean 162
Standard deviation 1.1e+02
Values 86 2.7e+02 56 2.3e+02
[92]
ref_hepatocyte MYH14
Mean 5.98
Standard deviation 2.3
Values 4.5 5.3 3.5 9.3 7.3
[93]
HepG2 MYH14
Mean 24.3
Standard deviation 8.5
Values 30 18
[94]
HepG2.C3A MYH14
Mean 23.4
Standard deviation 7
Values 28 18
[95]
HuH.7 MYH14
Mean 22.1
Standard deviation 4.6
Values 26 23 17
[96]
SNU475 MYH14
Mean 15.5
Standard deviation 1.9
Values 17 14
[97]
THLE MYH14
Mean 1.6
Standard deviation 1.1
Values 2.4 0.85
[98]
liver MYH14
Mean 20.2
Standard deviation 6.7
Values 20 21 12 28
[99]
ref_hepatocyte MYH10
Mean 5.81
Standard deviation 6.6
Values 17 5.7 1.9 1.6 2.5
[100]
HepG2 MYH10
Mean 64.6
Standard deviation 17
Values 53 76
[101]
HepG2.C3A MYH10
Mean 58.3
Standard deviation 5
Values 55 62
[102]
HuH.7 MYH10
Mean 82.4
Standard deviation 29
Values 1.1e+02 57 76
[103]
SNU475 MYH10
Mean 59.2
Standard deviation 10
Values 66 52
[104]
THLE MYH10
Mean 61.3
Standard deviation 12
Values 53 70
[105]
liver MYH10
Mean 34.4
Standard deviation 12
Values 23 47 25 43
[106]
ref_hepatocyte PLXNB1
Mean 5.41
Standard deviation 3
Values 5.5 2.5 2.4 7.7 9
[107]
HepG2 PLXNB1
Mean 57.8
Standard deviation 0.27
Values 58 58
[108]
HepG2.C3A PLXNB1
Mean 95.9
Standard deviation 18
Values 1.1e+02 83
[109]
HuH.7 PLXNB1
Mean 66.4
Standard deviation 8.5
Values 70 57 72
[110]
SNU475 PLXNB1
Mean 3.1
Standard deviation 1.9
Values 4.5 1.7
[111]
THLE PLXNB1
Mean 14.9
Standard deviation 0.65
Values 15 14
[112]
liver PLXNB1
Mean 72.9
Standard deviation 31
Values 53 82 44 1.1e+02
[113]
ref_hepatocyte ROCK2
Mean 5.22
Standard deviation 4.8
Values 11 9.5 3.5 0.65 1.3
[114]
HepG2 ROCK2
Mean 32
Standard deviation 6.2
Values 28 36
[115]
HepG2.C3A ROCK2
Mean 67.4
Standard deviation 23
Values 51 84
[116]
HuH.7 ROCK2
Mean 22.4
Standard deviation 6.9
Values 28 24 15
[117]
SNU475 ROCK2
Mean 59.5
Standard deviation 0.12
Values 59 60
[118]
THLE ROCK2
Mean 14.2
Standard deviation 4.3
Values 17 11
[119]
liver ROCK2
Mean 28.1
Standard deviation 15
Values 20 42 12 39
[120]
ref_hepatocyte MYL9
Mean 5.03
Standard deviation 4.9
Values 5.1 13 5.9 0.6 0.89
[121]
HepG2 MYL9
Mean 23.1
Standard deviation 1.3
Values 22 24
[122]
HepG2.C3A MYL9
Mean 18
Standard deviation 3.8
Values 15 21
[123]
HuH.7 MYL9
Mean 2.69
Standard deviation 0.26
Values 2.9 2.4 2.7
[124]
SNU475 MYL9
Mean 222
Standard deviation 1.5e+02
Values 3.3e+02 1.2e+02
[125]
THLE MYL9
Mean 42.5
Standard deviation 9.6
Values 36 49
[126]
liver MYL9
Mean 6.76
Standard deviation 7.5
Values 5.5 1.6 18 2.2
[127]
ref_hepatocyte ARHGAP35
Mean 4.46
Standard deviation 0.51
Values 4.9 3.9 3.9 4.9 4.7
[128]
HepG2 ARHGAP35
Mean 50
Standard deviation 5.1
Values 54 46
[129]
HepG2.C3A ARHGAP35
Mean 48.8
Standard deviation 9
Values 55 42
[130]
HuH.7 ARHGAP35
Mean 68.1
Standard deviation 17
Values 74 82 49
[131]
SNU475 ARHGAP35
Mean 54.6
Standard deviation 6.9
Values 59 50
[132]
THLE ARHGAP35
Mean 45.6
Standard deviation 4.8
Values 42 49
[133]
liver ARHGAP35
Mean 60.7
Standard deviation 27
Values 49 78 28 87
[134]
ref_hepatocyte LIMK2
Mean 3.59
Standard deviation 2.1
Values 1.5 3.8 4.5 6.5 1.6
[135]
HepG2 LIMK2
Mean 22.4
Standard deviation 2.3
Values 21 24
[136]
HepG2.C3A LIMK2
Mean 25.9
Standard deviation 5.4
Values 30 22
[137]
HuH.7 LIMK2
Mean 27.6
Standard deviation 1.4
Values 26 29 27
[138]
SNU475 LIMK2
Mean 8.52
Standard deviation 1
Values 7.8 9.3
[139]
THLE LIMK2
Mean 14.9
Standard deviation 3.1
Values 13 17
[140]
liver LIMK2
Mean 12.4
Standard deviation 4.3
Values 6.1 14 15 14
[141]
ref_hepatocyte LIMK1
Mean 2.47
Standard deviation 1.8
Values 1.9 3.4 5.1 1.2 0.66
[142]
HepG2 LIMK1
Mean 26.9
Standard deviation 5.2
Values 31 23
[143]
HepG2.C3A LIMK1
Mean 11.2
Standard deviation 0.18
Values 11 11
[144]
HuH.7 LIMK1
Mean 7.98
Standard deviation 3.2
Values 11 4.9 7.7
[145]
SNU475 LIMK1
Mean 51.7
Standard deviation 1.7
Values 53 50
[146]
THLE LIMK1
Mean 17
Standard deviation 2
Values 16 18
[147]
liver LIMK1
Mean 1.25
Standard deviation 0.53
Values 0.82 1.6 0.77 1.8
[148]
ref_hepatocyte ARHGEF11
Mean 1.73
Standard deviation 0.69
Values 2.9 1.8 1.5 1.4 1
[149]
HepG2 ARHGEF11
Mean 15.7
Standard deviation 3.6
Values 13 18
[150]
HepG2.C3A ARHGEF11
Mean 15.2
Standard deviation 0.47
Values 15 15
[151]
HuH.7 ARHGEF11
Mean 11.7
Standard deviation 1.5
Values 13 12 10
[152]
SNU475 ARHGEF11
Mean 30.6
Standard deviation 0.94
Values 31 30
[153]
THLE ARHGEF11
Mean 21
Standard deviation 3.3
Values 19 23
[154]
liver ARHGEF11
Mean 14.8
Standard deviation 6.5
Values 12 17 7.8 23
[155]
ref_hepatocyte SEMA4D
Mean 0.512
Standard deviation 0.38
Values 0.099 0.34 1.1 0.41 0.61
[156]
HepG2 SEMA4D
Mean 0.853
Standard deviation 0.74
Values 1.4 0.33
[157]
HepG2.C3A SEMA4D
Mean 1.3
Standard deviation 0.18
Values 1.2 1.4
[158]
HuH.7 SEMA4D
Mean 2.73
Standard deviation 0.62
Values 2.2 3.4 2.6
[159]
SNU475 SEMA4D
Mean 0.87
Standard deviation 0.63
Values 0.43 1.3
[160]
THLE SEMA4D
Mean 5.19
Standard deviation 0.23
Values 5.3 5
[161]
liver SEMA4D
Mean 3.13
Standard deviation 1.3
Values 2.4 3.6 1.8 4.7
[162]
ref_hepatocyte MYH11
Mean 0.00924
Standard deviation 0.021
Values 0 0 0.046 0 0
[163]
HepG2 MYH11
Mean 0.21
Standard deviation 0.067
Values 0.26 0.16
[164]
HepG2.C3A MYH11
Mean 0.145
Standard deviation 0.068
Values 0.097 0.19
[165]
HuH.7 MYH11
Mean 0.169
Standard deviation 0.067
Values 0.15 0.12 0.24
[166]
SNU475 MYH11
Mean 0.217
Standard deviation 0.044
Values 0.19 0.25
[167]
THLE MYH11
Mean 0.133
Standard deviation 0.03
Values 0.11 0.15
[168]
liver MYH11
Mean 13
Standard deviation 16
Values 3 6.1 6.2 37