REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 MYL6 Myosin light polypeptide 6 [1] -1.93[2] -1.42[3] -2.27[4] -1.41[5] -1.31[6] -2.16[7]
2 MYL12B Myosin regulatory light chain 12B [8] -0.67[9] -0.22[10] 0.05[11] -0.48[12] -0.74[13] -0.93[14]
3 RHOA Transforming protein RhoA [15] 0.40[16] 0.24[17] 0.76[18] -0.20[19] 0.71[20] 0.13[21]
4 RHOC Rho-related GTP-binding protein RhoC [22] -0.23[23] -0.30[24] -0.43[25] 0.02[26] 0.34[27] -1.24[28]
5 RHOB Rho-related GTP-binding protein RhoB [29] 0.55[30] 0.31[31] -1.53[32] -1.26[33] -1.66[34] 1.34[35]
6 MYH9 Myosin-9 [36] 2.76[37] 1.54[38] 1.80[39] 2.25[40] 2.59[41] 1.85[42]
7 RND1 Rho-related GTP-binding protein Rho6 [43] -3.91[44] -3.20[45] -1.87[46] -5.43[47] -4.60[48] -1.97[49]
8 ROCK1 Rho-associated protein kinase 1 [50] 0.39[51] 2.24[52] 3.32[53] 2.39[54] 2.19[55] 3.04[56]
9 ERBB2 Receptor tyrosine-protein kinase erbB-2 [57] 3.71[58] 2.86[59] 4.34[60] 2.28[61] 2.34[62] 1.61[63]
10 ARHGEF12 Rho guanine nucleotide exchange factor 12 [64] 3.35[65] 3.45[66] 3.39[67] 4.02[68] 3.64[69] 5.63[70]
11 MYH14 Myosin-14 [71] 2.22[72] 2.67[73] 2.94[74] 1.52[75] -1.46[76] 2.71[77]
12 MYH10 Myosin-10 [78] 3.67[79] 4.02[80] 4.88[81] 3.50[82] 3.84[83] 3.52[84]
13 PLXNB1 Plexin-B1 [85] 3.62[86] 4.85[87] 4.68[88] -0.65[89] 1.91[90] 4.71[91]
14 ROCK2 Rho-associated protein kinase 2 [92] 2.82[93] 4.39[94] 3.16[95] 3.66[96] 1.89[97] 3.38[98]
15 MYL9 Myosin regulatory light polypeptide 9 [99] 2.40[100] 2.54[101] 0.15[102] 5.61[103] 3.52[104] 1.38[105]
16 LIMK2 LIM domain kinase 2 [106] 2.84[107] 3.55[108] 4.00[109] 1.40[110] 2.49[111] 2.74[112]
17 LIMK1 LIM domain kinase 1 [113] 3.64[114] 2.87[115] 2.75[116] 4.54[117] 3.22[118] -0.03[119]
18 ARHGEF11 Rho guanine nucleotide exchange factor 11 [120] 3.38[121] 3.83[122] 3.82[123] 4.29[124] 4.04[125] 4.05[126]
19 SEMA4D Semaphorin-4D [127] 0.93[128] 2.04[129] 3.47[130] 0.92[131] 3.78[132] 3.57[133]
20 MYH11 Myosin-11 [134] 4.71[135] 4.67[136] 5.25[137] 4.70[138] 4.29[139] 11.42[140]
[1]
ref_hepatocyte MYL6
Mean 1.19e+03
Standard deviation 1.2e+03
Values 9.4e+02 3.2e+03 7.6e+02 5.1e+02 5.1e+02
[2]
HepG2 MYL6
Mean 272
Standard deviation 59
Values 2.3e+02 3.1e+02
[3]
HepG2.C3A MYL6
Mean 275
Standard deviation 92
Values 2.1e+02 3.4e+02
[4]
HuH.7 MYL6
Mean 118
Standard deviation 30
Values 1.1e+02 94 1.5e+02
[5]
SNU475 MYL6
Mean 403
Standard deviation 1.9e+02
Values 5.4e+02 2.7e+02
[6]
THLE MYL6
Mean 354
Standard deviation 52
Values 3.2e+02 3.9e+02
[7]
liver MYL6
Mean 138
Standard deviation 1.3e+02
Values 2.6e+02 37 2.3e+02 21
[8]
ref_hepatocyte MYL12B
Mean 317
Standard deviation 2e+02
Values 2e+02 6.8e+02 2.5e+02 2.4e+02 2.1e+02
[9]
HepG2 MYL12B
Mean 174
Standard deviation 36
Values 1.5e+02 2e+02
[10]
HepG2.C3A MYL12B
Mean 168
Standard deviation 40
Values 1.4e+02 2e+02
[11]
HuH.7 MYL12B
Mean 158
Standard deviation 19
Values 1.5e+02 1.4e+02 1.8e+02
[12]
SNU475 MYL12B
Mean 204
Standard deviation 67
Values 2.5e+02 1.6e+02
[13]
THLE MYL12B
Mean 140
Standard deviation 22
Values 1.2e+02 1.6e+02
[14]
liver MYL12B
Mean 85.6
Standard deviation 68
Values 1.5e+02 34 1.4e+02 20
[15]
ref_hepatocyte RHOA
Mean 177
Standard deviation 1.2e+02
Values 2.2e+02 3.8e+02 1.4e+02 75 79
[16]
HepG2 RHOA
Mean 204
Standard deviation 38
Values 2.3e+02 1.8e+02
[17]
HepG2.C3A RHOA
Mean 129
Standard deviation 1.6
Values 1.3e+02 1.3e+02
[18]
HuH.7 RHOA
Mean 144
Standard deviation 23
Values 1.6e+02 1.2e+02 1.6e+02
[19]
SNU475 RHOA
Mean 139
Standard deviation 21
Values 1.5e+02 1.2e+02
[20]
THLE RHOA
Mean 214
Standard deviation 38
Values 1.9e+02 2.4e+02
[21]
liver RHOA
Mean 101
Standard deviation 59
Values 1.6e+02 54 1.4e+02 46
[22]
ref_hepatocyte RHOC
Mean 128
Standard deviation 1.2e+02
Values 28 2.1e+02 3.1e+02 56 39
[23]
HepG2 RHOC
Mean 95.1
Standard deviation 9.4
Values 1e+02 88
[24]
HepG2.C3A RHOC
Mean 64.3
Standard deviation 2.3
Values 66 63
[25]
HuH.7 RHOC
Mean 45.7
Standard deviation 7.4
Values 39 53 45
[26]
SNU475 RHOC
Mean 117
Standard deviation 12
Values 1.3e+02 1.1e+02
[27]
THLE RHOC
Mean 120
Standard deviation 7.4
Values 1.1e+02 1.3e+02
[28]
liver RHOC
Mean 28.1
Standard deviation 21
Values 52 13 38 9.2
[29]
ref_hepatocyte RHOB
Mean 121
Standard deviation 74
Values 81 64 88 2.5e+02 1.3e+02
[30]
HepG2 RHOB
Mean 154
Standard deviation 31
Values 1.8e+02 1.3e+02
[31]
HepG2.C3A RHOB
Mean 92.7
Standard deviation 27
Values 1.1e+02 74
[32]
HuH.7 RHOB
Mean 20.2
Standard deviation 3.4
Values 17 24 20
[33]
SNU475 RHOB
Mean 45.5
Standard deviation 23
Values 61 30
[34]
THLE RHOB
Mean 28.2
Standard deviation 1.3
Values 27 29
[35]
liver RHOB
Mean 158
Standard deviation 87
Values 1.3e+02 1.5e+02 71 2.8e+02
[36]
ref_hepatocyte MYH9
Mean 89.9
Standard deviation 85
Values 42 2e+02 1.7e+02 21 22
[37]
HepG2 MYH9
Mean 531
Standard deviation 80
Values 5.9e+02 4.7e+02
[38]
HepG2.C3A MYH9
Mean 161
Standard deviation 42
Values 1.9e+02 1.3e+02
[39]
HuH.7 MYH9
Mean 151
Standard deviation 45
Values 2e+02 1.3e+02 1.2e+02
[40]
SNU475 MYH9
Mean 384
Standard deviation 1.4e+02
Values 4.8e+02 2.9e+02
[41]
THLE MYH9
Mean 399
Standard deviation 1.2e+02
Values 3.1e+02 4.9e+02
[42]
liver MYH9
Mean 167
Standard deviation 46
Values 1.1e+02 2e+02 1.5e+02 2.1e+02
[43]
ref_hepatocyte RND1
Mean 26.9
Standard deviation 39
Values 0.28 4 94 26 9.9
[44]
HepG2 RND1
Mean 1.56
Standard deviation 0.15
Values 1.5 1.7
[45]
HepG2.C3A RND1
Mean 1.81
Standard deviation 0.44
Values 2.1 1.5
[46]
HuH.7 RND1
Mean 3.55
Standard deviation 0.96
Values 2.5 3.9 4.3
[47]
SNU475 RND1
Mean 0.562
Standard deviation 0.37
Values 0.82 0.3
[48]
THLE RND1
Mean 0.817
Standard deviation 0.2
Values 0.96 0.68
[49]
liver RND1
Mean 3.54
Standard deviation 0.89
Values 3.4 3.3 4.8 2.7
[50]
ref_hepatocyte ROCK1
Mean 6.73
Standard deviation 4.9
Values 9.7 14 3.6 2.5 3.9
[51]
HepG2 ROCK1
Mean 7.68
Standard deviation 2.4
Values 6 9.4
[52]
HepG2.C3A ROCK1
Mean 19.7
Standard deviation 1.6
Values 19 21
[53]
HuH.7 ROCK1
Mean 32.3
Standard deviation 9
Values 36 39 22
[54]
SNU475 ROCK1
Mean 31.8
Standard deviation 1.6
Values 31 33
[55]
THLE ROCK1
Mean 22.6
Standard deviation 6.2
Values 27 18
[56]
liver ROCK1
Mean 28.7
Standard deviation 3.4
Values 30 32 25 27
[57]
ref_hepatocyte ERBB2
Mean 6.44
Standard deviation 3.8
Values 13 3.9 4.7 3.7 7.1
[58]
HepG2 ERBB2
Mean 73.6
Standard deviation 10
Values 66 81
[59]
HepG2.C3A ERBB2
Mean 29
Standard deviation 6.9
Values 34 24
[60]
HuH.7 ERBB2
Mean 62.5
Standard deviation 7.1
Values 69 55 63
[61]
SNU475 ERBB2
Mean 28.2
Standard deviation 8.4
Values 34 22
[62]
THLE ERBB2
Mean 24.1
Standard deviation 2.7
Values 22 26
[63]
liver ERBB2
Mean 10.2
Standard deviation 3.4
Values 7.9 8.1 9.6 15
[64]
ref_hepatocyte ARHGEF12
Mean 6.33
Standard deviation 3.3
Values 5.1 6.1 2.5 6.3 12
[65]
HepG2 ARHGEF12
Mean 56.4
Standard deviation 18
Values 44 69
[66]
HepG2.C3A ARHGEF12
Mean 42.7
Standard deviation 1.7
Values 42 44
[67]
HuH.7 ARHGEF12
Mean 31.9
Standard deviation 7.3
Values 37 36 23
[68]
SNU475 ARHGEF12
Mean 92.7
Standard deviation 12
Values 1e+02 84
[69]
THLE ARHGEF12
Mean 58.1
Standard deviation 5.9
Values 54 62
[70]
liver ARHGEF12
Mean 162
Standard deviation 1.1e+02
Values 86 2.7e+02 56 2.3e+02
[71]
ref_hepatocyte MYH14
Mean 5.98
Standard deviation 2.3
Values 4.5 5.3 3.5 9.3 7.3
[72]
HepG2 MYH14
Mean 24.3
Standard deviation 8.5
Values 30 18
[73]
HepG2.C3A MYH14
Mean 23.4
Standard deviation 7
Values 28 18
[74]
HuH.7 MYH14
Mean 22.1
Standard deviation 4.6
Values 26 23 17
[75]
SNU475 MYH14
Mean 15.5
Standard deviation 1.9
Values 17 14
[76]
THLE MYH14
Mean 1.6
Standard deviation 1.1
Values 2.4 0.85
[77]
liver MYH14
Mean 20.2
Standard deviation 6.7
Values 20 21 12 28
[78]
ref_hepatocyte MYH10
Mean 5.81
Standard deviation 6.6
Values 17 5.7 1.9 1.6 2.5
[79]
HepG2 MYH10
Mean 64.6
Standard deviation 17
Values 53 76
[80]
HepG2.C3A MYH10
Mean 58.3
Standard deviation 5
Values 55 62
[81]
HuH.7 MYH10
Mean 82.4
Standard deviation 29
Values 1.1e+02 57 76
[82]
SNU475 MYH10
Mean 59.2
Standard deviation 10
Values 66 52
[83]
THLE MYH10
Mean 61.3
Standard deviation 12
Values 53 70
[84]
liver MYH10
Mean 34.4
Standard deviation 12
Values 23 47 25 43
[85]
ref_hepatocyte PLXNB1
Mean 5.41
Standard deviation 3
Values 5.5 2.5 2.4 7.7 9
[86]
HepG2 PLXNB1
Mean 57.8
Standard deviation 0.27
Values 58 58
[87]
HepG2.C3A PLXNB1
Mean 95.9
Standard deviation 18
Values 1.1e+02 83
[88]
HuH.7 PLXNB1
Mean 66.4
Standard deviation 8.5
Values 70 57 72
[89]
SNU475 PLXNB1
Mean 3.1
Standard deviation 1.9
Values 4.5 1.7
[90]
THLE PLXNB1
Mean 14.9
Standard deviation 0.65
Values 15 14
[91]
liver PLXNB1
Mean 72.9
Standard deviation 31
Values 53 82 44 1.1e+02
[92]
ref_hepatocyte ROCK2
Mean 5.22
Standard deviation 4.8
Values 11 9.5 3.5 0.65 1.3
[93]
HepG2 ROCK2
Mean 32
Standard deviation 6.2
Values 28 36
[94]
HepG2.C3A ROCK2
Mean 67.4
Standard deviation 23
Values 51 84
[95]
HuH.7 ROCK2
Mean 22.4
Standard deviation 6.9
Values 28 24 15
[96]
SNU475 ROCK2
Mean 59.5
Standard deviation 0.12
Values 59 60
[97]
THLE ROCK2
Mean 14.2
Standard deviation 4.3
Values 17 11
[98]
liver ROCK2
Mean 28.1
Standard deviation 15
Values 20 42 12 39
[99]
ref_hepatocyte MYL9
Mean 5.03
Standard deviation 4.9
Values 5.1 13 5.9 0.6 0.89
[100]
HepG2 MYL9
Mean 23.1
Standard deviation 1.3
Values 22 24
[101]
HepG2.C3A MYL9
Mean 18
Standard deviation 3.8
Values 15 21
[102]
HuH.7 MYL9
Mean 2.69
Standard deviation 0.26
Values 2.9 2.4 2.7
[103]
SNU475 MYL9
Mean 222
Standard deviation 1.5e+02
Values 3.3e+02 1.2e+02
[104]
THLE MYL9
Mean 42.5
Standard deviation 9.6
Values 36 49
[105]
liver MYL9
Mean 6.76
Standard deviation 7.5
Values 5.5 1.6 18 2.2
[106]
ref_hepatocyte LIMK2
Mean 3.59
Standard deviation 2.1
Values 1.5 3.8 4.5 6.5 1.6
[107]
HepG2 LIMK2
Mean 22.4
Standard deviation 2.3
Values 21 24
[108]
HepG2.C3A LIMK2
Mean 25.9
Standard deviation 5.4
Values 30 22
[109]
HuH.7 LIMK2
Mean 27.6
Standard deviation 1.4
Values 26 29 27
[110]
SNU475 LIMK2
Mean 8.52
Standard deviation 1
Values 7.8 9.3
[111]
THLE LIMK2
Mean 14.9
Standard deviation 3.1
Values 13 17
[112]
liver LIMK2
Mean 12.4
Standard deviation 4.3
Values 6.1 14 15 14
[113]
ref_hepatocyte LIMK1
Mean 2.47
Standard deviation 1.8
Values 1.9 3.4 5.1 1.2 0.66
[114]
HepG2 LIMK1
Mean 26.9
Standard deviation 5.2
Values 31 23
[115]
HepG2.C3A LIMK1
Mean 11.2
Standard deviation 0.18
Values 11 11
[116]
HuH.7 LIMK1
Mean 7.98
Standard deviation 3.2
Values 11 4.9 7.7
[117]
SNU475 LIMK1
Mean 51.7
Standard deviation 1.7
Values 53 50
[118]
THLE LIMK1
Mean 17
Standard deviation 2
Values 16 18
[119]
liver LIMK1
Mean 1.25
Standard deviation 0.53
Values 0.82 1.6 0.77 1.8
[120]
ref_hepatocyte ARHGEF11
Mean 1.73
Standard deviation 0.69
Values 2.9 1.8 1.5 1.4 1
[121]
HepG2 ARHGEF11
Mean 15.7
Standard deviation 3.6
Values 13 18
[122]
HepG2.C3A ARHGEF11
Mean 15.2
Standard deviation 0.47
Values 15 15
[123]
HuH.7 ARHGEF11
Mean 11.7
Standard deviation 1.5
Values 13 12 10
[124]
SNU475 ARHGEF11
Mean 30.6
Standard deviation 0.94
Values 31 30
[125]
THLE ARHGEF11
Mean 21
Standard deviation 3.3
Values 19 23
[126]
liver ARHGEF11
Mean 14.8
Standard deviation 6.5
Values 12 17 7.8 23
[127]
ref_hepatocyte SEMA4D
Mean 0.512
Standard deviation 0.38
Values 0.099 0.34 1.1 0.41 0.61
[128]
HepG2 SEMA4D
Mean 0.853
Standard deviation 0.74
Values 1.4 0.33
[129]
HepG2.C3A SEMA4D
Mean 1.3
Standard deviation 0.18
Values 1.2 1.4
[130]
HuH.7 SEMA4D
Mean 2.73
Standard deviation 0.62
Values 2.2 3.4 2.6
[131]
SNU475 SEMA4D
Mean 0.87
Standard deviation 0.63
Values 0.43 1.3
[132]
THLE SEMA4D
Mean 5.19
Standard deviation 0.23
Values 5.3 5
[133]
liver SEMA4D
Mean 3.13
Standard deviation 1.3
Values 2.4 3.6 1.8 4.7
[134]
ref_hepatocyte MYH11
Mean 0.00924
Standard deviation 0.021
Values 0 0 0.046 0 0
[135]
HepG2 MYH11
Mean 0.21
Standard deviation 0.067
Values 0.26 0.16
[136]
HepG2.C3A MYH11
Mean 0.145
Standard deviation 0.068
Values 0.097 0.19
[137]
HuH.7 MYH11
Mean 0.169
Standard deviation 0.067
Values 0.15 0.12 0.24
[138]
SNU475 MYH11
Mean 0.217
Standard deviation 0.044
Values 0.19 0.25
[139]
THLE MYH11
Mean 0.133
Standard deviation 0.03
Values 0.11 0.15
[140]
liver MYH11
Mean 13
Standard deviation 16
Values 3 6.1 6.2 37