REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 HSP90AB1 Heat shock protein HSP 90-beta [1] 0.26[2] 0.20[3] -0.07[4] -0.45[5] -0.80[6] -0.90[7]
2 HSP90AA1 Heat shock protein HSP 90-alpha [8] -0.61[9] 0.20[10] -0.03[11] 0.18[12] 0.15[13] -0.06[14]
3 CFL1 Cofilin-1 [15] -0.23[16] -1.41[17] -0.89[18] -0.38[19] -0.03[20] 0.26[21]
4 RAC1 Ras-related C3 botulinum toxin substrate 1 [22] -0.36[23] -0.85[24] 0.40[25] 0.11[26] 0.37[27] 0.23[28]
5 PAK2 Serine/threonine-protein kinase PAK 2 [29] 1.48[30] 1.07[31] 1.90[32] 0.85[33] 1.67[34] 2.56[35]
6 NRP1 Neuropilin-1 [36] 1.57[37] -0.77[38] 3.70[39] 4.04[40] 3.79[41] 4.41[42]
7 FES Tyrosine-protein kinase Fes/Fps [43] 0.81[44] -1.34[45] -0.45[46] -6.52[47] -1.96[48] 2.38[49]
8 LIMK1 LIM domain kinase 1 [50] 2.33[51] 1.07[52] 1.19[53] 3.60[54] 2.11[55] -0.29[56]
9 PAK1 Serine/threonine-protein kinase PAK 1 [57] 0.02[58] -0.90[59] 2.05[60] -1.76[61] 2.29[62] 1.47[63]
10 FYN Tyrosine-protein kinase Fyn [64] 0.97[65] -7.78[66] 1.32[67] 1.56[68] 3.37[69] 2.17[70]
11 PLXNA1 Plexin-A1 [71] 4.05[72] 3.15[73] 3.45[74] 3.66[75] 4.10[76] 3.47[77]
12 PLXNA2 Plexin-A2 [78] 3.40[79] 2.08[80] -0.01[81] 2.85[82] 4.66[83] 4.51[84]
13 PLXNA3 Plexin-A3 [85] 4.05[86] 3.36[87] 2.71[88] 4.66[89] 4.14[90] 3.01[91]
14 PAK3 Serine/threonine-protein kinase PAK 3 [92] -6.38[93] [94] [95] -1.51[96] 0.49[97] 1.98[98]
15 PLXNA4 Plexin-A4 [99] 0.58[100] -1.93[101] -3.60[102] 1.31[103] -0.34[104] 6.03[105]
16 SEMA3A Semaphorin-3A [106] 5.97[107] 8.45[108] 9.11[109] 7.39[110] 8.57[111] 5.35[112]
[1]
ref_hepatocyte HSP90AB1
Mean 469
Standard deviation 3.2e+02
Values 8.1e+02 7.8e+02 4e+02 2.1e+02 1.4e+02
[2]
HepG2 HSP90AB1
Mean 1.22e+03
Standard deviation 89
Values 1.2e+03 1.3e+03
[3]
HepG2.C3A HSP90AB1
Mean 1.16e+03
Standard deviation 1.2e+02
Values 1.2e+03 1.1e+03
[4]
HuH.7 HSP90AB1
Mean 634
Standard deviation 9.5
Values 6.3e+02 6.2e+02 6.4e+02
[5]
SNU475 HSP90AB1
Mean 591
Standard deviation 65
Values 5.4e+02 6.4e+02
[6]
THLE HSP90AB1
Mean 431
Standard deviation 80
Values 3.7e+02 4.9e+02
[7]
liver HSP90AB1
Mean 156
Standard deviation 26
Values 1.5e+02 1.4e+02 1.9e+02 1.3e+02
[8]
ref_hepatocyte HSP90AA1
Mean 356
Standard deviation 2.5e+02
Values 5.4e+02 6.9e+02 1.3e+02 2.5e+02 1.7e+02
[9]
HepG2 HSP90AA1
Mean 503
Standard deviation 2.6e+02
Values 3.2e+02 6.9e+02
[10]
HepG2.C3A HSP90AA1
Mean 878
Standard deviation 5.2e+02
Values 5.1e+02 1.2e+03
[11]
HuH.7 HSP90AA1
Mean 494
Standard deviation 76
Values 5.4e+02 4.1e+02 5.4e+02
[12]
SNU475 HSP90AA1
Mean 696
Standard deviation 1.5e+02
Values 5.9e+02 8e+02
[13]
THLE HSP90AA1
Mean 627
Standard deviation 16
Values 6.4e+02 6.2e+02
[14]
liver HSP90AA1
Mean 212
Standard deviation 50
Values 2.7e+02 1.9e+02 2.4e+02 1.6e+02
[15]
ref_hepatocyte CFL1
Mean 201
Standard deviation 66
Values 1.2e+02 2.6e+02 2.6e+02 2.3e+02 1.5e+02
[16]
HepG2 CFL1
Mean 370
Standard deviation 16
Values 3.8e+02 3.6e+02
[17]
HepG2.C3A CFL1
Mean 162
Standard deviation 39
Values 1.3e+02 1.9e+02
[18]
HuH.7 CFL1
Mean 154
Standard deviation 66
Values 1.8e+02 78 2e+02
[19]
SNU475 CFL1
Mean 267
Standard deviation 62
Values 3.1e+02 2.2e+02
[20]
THLE CFL1
Mean 313
Standard deviation 56
Values 2.7e+02 3.5e+02
[21]
liver CFL1
Mean 148
Standard deviation 1.2e+02
Values 2.4e+02 50 2.7e+02 36
[22]
ref_hepatocyte RAC1
Mean 52
Standard deviation 20
Values 28 59 81 45 47
[23]
HepG2 RAC1
Mean 87.4
Standard deviation 1.9
Values 89 86
[24]
HepG2.C3A RAC1
Mean 62
Standard deviation 7.4
Values 67 57
[25]
HuH.7 RAC1
Mean 97.2
Standard deviation 9.7
Values 1e+02 86 1e+02
[26]
SNU475 RAC1
Mean 96.5
Standard deviation 10
Values 89 1e+02
[27]
THLE RAC1
Mean 107
Standard deviation 19
Values 94 1.2e+02
[28]
liver RAC1
Mean 37.8
Standard deviation 32
Values 63 12 67 9.5
[29]
ref_hepatocyte PAK2
Mean 10.9
Standard deviation 2.8
Values 11 15 11 7.6 9.9
[30]
HepG2 PAK2
Mean 65.6
Standard deviation 14
Values 56 75
[31]
HepG2.C3A PAK2
Mean 49.1
Standard deviation 0.79
Values 49 50
[32]
HuH.7 PAK2
Mean 57.7
Standard deviation 11
Values 66 61 46
[33]
SNU475 PAK2
Mean 33.8
Standard deviation 4.3
Values 37 31
[34]
THLE PAK2
Mean 55.3
Standard deviation 9.9
Values 48 62
[35]
liver PAK2
Mean 39.9
Standard deviation 5.7
Values 44 41 43 32
[36]
ref_hepatocyte NRP1
Mean 3.57
Standard deviation 2.4
Values 1.1 3.2 2.9 7.6 3
[37]
HepG2 NRP1
Mean 22.9
Standard deviation 1.8
Values 24 22
[38]
HepG2.C3A NRP1
Mean 4.49
Standard deviation 0.63
Values 4.9 4
[39]
HuH.7 NRP1
Mean 65.7
Standard deviation 11
Values 70 74 53
[40]
SNU475 NRP1
Mean 101
Standard deviation 18
Values 88 1.1e+02
[41]
THLE NRP1
Mean 78.4
Standard deviation 14
Values 68 89
[42]
liver NRP1
Mean 46.9
Standard deviation 15
Values 26 61 47 53
[43]
ref_hepatocyte FES
Mean 3.44
Standard deviation 3.5
Values 2.1 0.42 1.4 3.9 9.3
[44]
HepG2 FES
Mean 13
Standard deviation 1.1
Values 12 14
[45]
HepG2.C3A FES
Mean 2.91
Standard deviation 1.3
Values 2 3.8
[46]
HuH.7 FES
Mean 3.58
Standard deviation 0.35
Values 3.6 3.2 3.9
[47]
SNU475 FES
Mean 0.0644
Standard deviation 0.045
Values 0.032 0.096
[48]
THLE FES
Mean 1.41
Standard deviation 0.092
Values 1.3 1.5
[49]
liver FES
Mean 11.1
Standard deviation 3.5
Values 16 7.9 9.8 10
[50]
ref_hepatocyte LIMK1
Mean 2.47
Standard deviation 1.8
Values 1.9 3.4 5.1 1.2 0.66
[51]
HepG2 LIMK1
Mean 26.9
Standard deviation 5.2
Values 31 23
[52]
HepG2.C3A LIMK1
Mean 11.2
Standard deviation 0.18
Values 11 11
[53]
HuH.7 LIMK1
Mean 7.98
Standard deviation 3.2
Values 11 4.9 7.7
[54]
SNU475 LIMK1
Mean 51.7
Standard deviation 1.7
Values 53 50
[55]
THLE LIMK1
Mean 17
Standard deviation 2
Values 16 18
[56]
liver LIMK1
Mean 1.25
Standard deviation 0.53
Values 0.82 1.6 0.77 1.8
[57]
ref_hepatocyte PAK1
Mean 2.3
Standard deviation 0.59
Values 1.7 3 2.9 2.1 1.9
[58]
HepG2 PAK1
Mean 5.05
Standard deviation 1.5
Values 6.1 4
[59]
HepG2.C3A PAK1
Mean 2.65
Standard deviation 0.51
Values 3 2.3
[60]
HuH.7 PAK1
Mean 13.5
Standard deviation 2.2
Values 12 16 12
[61]
SNU475 PAK1
Mean 1.17
Standard deviation 0.24
Values 1 1.3
[62]
THLE PAK1
Mean 18
Standard deviation 0.72
Values 18 17
[63]
liver PAK1
Mean 3.94
Standard deviation 1.1
Values 5.3 4 3.9 2.6
[64]
ref_hepatocyte FYN
Mean 2.1
Standard deviation 2.2
Values 2.2 0.039 0.23 2.6 5.5
[65]
HepG2 FYN
Mean 8.91
Standard deviation 0.7
Values 9.4 8.4
[66]
HepG2.C3A FYN
Mean 0.0204
Standard deviation 0.0014
Values 0.019 0.021
[67]
HuH.7 FYN
Mean 7.43
Standard deviation 2.2
Values 8.9 4.8 8.5
[68]
SNU475 FYN
Mean 10.7
Standard deviation 2.5
Values 12 8.9
[69]
THLE FYN
Mean 34.5
Standard deviation 4.9
Values 38 31
[70]
liver FYN
Mean 5.84
Standard deviation 2.1
Values 8.9 4.4 5.1 5
[71]
ref_hepatocyte PLXNA1
Mean 1.11
Standard deviation 0.79
Values 1.9 1.6 1.6 0.26 0.24
[72]
HepG2 PLXNA1
Mean 39.7
Standard deviation 5.9
Values 44 36
[73]
HepG2.C3A PLXNA1
Mean 21
Standard deviation 3.2
Values 23 19
[74]
HuH.7 PLXNA1
Mean 17.2
Standard deviation 2.8
Values 20 15 16
[75]
SNU475 PLXNA1
Mean 24.1
Standard deviation 4.2
Values 27 21
[76]
THLE PLXNA1
Mean 30.3
Standard deviation 6.8
Values 26 35
[77]
liver PLXNA1
Mean 7.56
Standard deviation 5
Values 4 11 2.6 13
[78]
ref_hepatocyte PLXNA2
Mean 0.684
Standard deviation 0.54
Values 0.021 1.3 1.1 0.63 0.33
[79]
HepG2 PLXNA2
Mean 15.6
Standard deviation 2
Values 17 14
[80]
HepG2.C3A PLXNA2
Mean 6.2
Standard deviation 1
Values 5.5 6.9
[81]
HuH.7 PLXNA2
Mean 0.962
Standard deviation 0.34
Values 1.3 0.89 0.67
[82]
SNU475 PLXNA2
Mean 8.49
Standard deviation 1.2
Values 9.3 7.7
[83]
THLE PLXNA2
Mean 27.5
Standard deviation 1.5
Values 26 29
[84]
liver PLXNA2
Mean 9.64
Standard deviation 4.6
Values 5.4 13 6.1 14
[85]
ref_hepatocyte PLXNA3
Mean 0.461
Standard deviation 0.26
Values 0.71 0.71 0.51 0.16 0.22
[86]
HepG2 PLXNA3
Mean 16.5
Standard deviation 0.39
Values 16 17
[87]
HepG2.C3A PLXNA3
Mean 10.2
Standard deviation 3.8
Values 13 7.5
[88]
HuH.7 PLXNA3
Mean 4.27
Standard deviation 1
Values 3.5 5.5 3.9
[89]
SNU475 PLXNA3
Mean 20
Standard deviation 8.7
Values 26 14
[90]
THLE PLXNA3
Mean 12.9
Standard deviation 1.8
Values 14 12
[91]
liver PLXNA3
Mean 2.3
Standard deviation 1.4
Values 0.94 4 2.7 1.5
[92]
ref_hepatocyte PAK3
Mean 0.0826
Standard deviation 0.14
Values 0 0 0.33 0 0.081
[93]
HepG2 PAK3
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[94]
HepG2.C3A PAK3
Mean 0
Standard deviation 0
Values 0 0
[95]
HuH.7 PAK3
Mean 0
Standard deviation 0
Values 0 0 0
[96]
SNU475 PAK3
Mean 0.05
Standard deviation 0.051
Values 0.014 0.086
[97]
THLE PAK3
Mean 0.185
Standard deviation 0.065
Values 0.23 0.14
[98]
liver PAK3
Mean 0.202
Standard deviation 0.041
Values 0.24 0.14 0.21 0.23
[99]
ref_hepatocyte PLXNA4
Mean 0.0268
Standard deviation 0.029
Values 0 0 0.033 0.069 0.033
[100]
HepG2 PLXNA4
Mean 0.0866
Standard deviation 0.08
Values 0.14 0.03
[101]
HepG2.C3A PLXNA4
Mean 0.0151
Standard deviation 0.0062
Values 0.019 0.011
[102]
HuH.7 PLXNA4
Mean 0.00312
Standard deviation 0.0054
Values 0 0 0.0094
[103]
SNU475 PLXNA4
Mean 0.115
Standard deviation 0.11
Values 0.037 0.19
[104]
THLE PLXNA4
Mean 0.0337
Standard deviation 0.0025
Values 0.035 0.032
[105]
liver PLXNA4
Mean 1.08
Standard deviation 1
Values 0.31 1.4 0.28 2.4
[106]
ref_hepatocyte SEMA3A
Mean 0.0116
Standard deviation 0.012
Values 0.021 0 0.011 0.026 0
[107]
HepG2 SEMA3A
Mean 1.57
Standard deviation 0.43
Values 1.9 1.3
[108]
HepG2.C3A SEMA3A
Mean 8.69
Standard deviation 1.8
Values 10 7.4
[109]
HuH.7 SEMA3A
Mean 9.06
Standard deviation 1.4
Values 11 7.9 8.6
[110]
SNU475 SEMA3A
Mean 3.35
Standard deviation 0.58
Values 2.9 3.8
[111]
THLE SEMA3A
Mean 6.99
Standard deviation 1.8
Values 8.2 5.7
[112]
liver SEMA3A
Mean 0.293
Standard deviation 0.17
Values 0.14 0.39 0.15 0.49