REACTOME_SELECTIVE_AUTOPHAGY | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | UBB | Polyubiquitin-B | [1] | -1.34[2] | -1.61[3] | -1.25[4] | -1.97[5] | -1.51[6] | -0.62[7] |
2 | SQSTM1 | Sequestosome-1 | [8] | -0.90[9] | -2.02[10] | -1.26[11] | -0.36[12] | -0.45[13] | -0.53[14] |
3 | RPS27A | Ubiquitin-40S ribosomal protein S27a | [15] | [16] | [17] | [18] | [19] | [20] | [21] |
4 | UBC | Polyubiquitin-C | [22] | -0.90[23] | -0.86[24] | -0.88[25] | -1.12[26] | -1.13[27] | -0.17[28] |
5 | HSPA8 | Heat shock cognate 71 kDa protein | [29] | 0.53[30] | 0.47[31] | -0.01[32] | 0.77[33] | 0.47[34] | 0.18[35] |
6 | HSP90AA1 | Heat shock protein HSP 90-alpha | [36] | 0.21[37] | 1.11[38] | 0.56[39] | 0.90[40] | 0.58[41] | 0.00[42] |
7 | TUBA1B | Tubulin alpha-1B chain | [43] | 0.01[44] | -0.04[45] | 0.41[46] | -0.14[47] | 0.42[48] | -1.29[49] |
8 | TUBA1C | Tubulin alpha-1C chain | [50] | -0.60[51] | -0.74[52] | -1.03[53] | -0.80[54] | -1.18[55] | -2.52[56] |
9 | TUBB4B | Tubulin beta-4B chain | [57] | 0.07[58] | -0.10[59] | 0.09[60] | -0.83[61] | 0.06[62] | -0.20[63] |
10 | PARK7 | Protein/nucleic acid deglycase DJ-1 | [64] | -0.73[65] | 0.01[66] | -1.02[67] | -0.97[68] | -0.99[69] | -0.38[70] |
11 | DYNLL1 | Dynein light chain 1, cytoplasmic | [71] | -0.53[72] | -0.56[73] | -0.56[74] | -0.81[75] | -1.09[76] | -0.84[77] |
12 | VDAC1 | Voltage-dependent anion-selective channel protein 1 | [78] | 0.50[79] | 0.06[80] | 0.06[81] | -0.04[82] | 0.23[83] | 0.33[84] |
13 | VCP | Transitional endoplasmic reticulum ATPase | [85] | 1.09[86] | 0.76[87] | 0.90[88] | 0.31[89] | 0.87[90] | 1.50[91] |
14 | PLIN2 | Perilipin-2 | [92] | 2.11[93] | 1.87[94] | 0.65[95] | -2.05[96] | 1.90[97] | 2.58[98] |
15 | TUBA4A | Tubulin alpha-4A chain | [99] | -3.19[100] | -3.43[101] | -3.99[102] | -0.99[103] | -1.16[104] | -1.36[105] |
16 | TUBB2A | Tubulin beta-2A chain | [106] | -2.37[107] | -2.54[108] | -1.06[109] | -1.32[110] | -3.59[111] | -1.52[112] |
17 | TOMM6 | Mitochondrial import receptor subunit TOM6 homolog | [113] | -0.23[114] | 0.17[115] | -0.45[116] | -0.72[117] | -1.25[118] | -1.28[119] |
18 | UBA52 | Ubiquitin-60S ribosomal protein L40 | [120] | 1.53[121] | 1.38[122] | 2.63[123] | 0.28[124] | 1.09[125] | 0.60[126] |
19 | TOMM5 | Mitochondrial import receptor subunit TOM5 homolog | [127] | -0.20[128] | 0.26[129] | 0.81[130] | -1.88[131] | -0.88[132] | -0.79[133] |
20 | VIM | Vimentin | [134] | -7.49[135] | -8.00[136] | -2.13[137] | 3.41[138] | 2.83[139] | 0.02[140] |
21 | TOMM7 | Mitochondrial import receptor subunit TOM7 homolog | [141] | -1.32[142] | -0.55[143] | 1.08[144] | -1.41[145] | -1.28[146] | -0.66[147] |
22 | CSNK2B | Casein kinase II subunit beta | [148] | 0.51[149] | 0.28[150] | -0.13[151] | -0.19[152] | -0.45[153] | -0.25[154] |
23 | TOMM22 | Mitochondrial import receptor subunit TOM22 homolog | [155] | -0.28[156] | -0.33[157] | 0.28[158] | -1.46[159] | -1.14[160] | -0.39[161] |
24 | TOMM20 | Mitochondrial import receptor subunit TOM20 homolog | [162] | 1.54[163] | 2.17[164] | 2.79[165] | 1.50[166] | 0.92[167] | 0.28[168] |
25 | CSNK2A1 | Casein kinase II subunit alpha | [169] | 0.97[170] | 0.78[171] | 0.92[172] | 0.45[173] | 0.09[174] | -0.47[175] |
26 | DYNLL2 | Dynein light chain 2, cytoplasmic | [176] | -0.11[177] | -0.73[178] | -0.30[179] | -2.06[180] | -0.48[181] | -1.68[182] |
27 | UBE2V1 | Ubiquitin-conjugating enzyme E2 variant 1 | [183] | -3.02[184] | -3.28[185] | -2.92[186] | -3.08[187] | -3.73[188] | -3.75[189] |
28 | PINK1 | Serine/threonine-protein kinase PINK1, mitochondrial | [190] | -0.26[191] | 0.46[192] | -2.29[193] | -0.22[194] | -0.43[195] | 1.70[196] |
29 | TOMM40 | Mitochondrial import receptor subunit TOM40 homolog | [197] | 1.05[198] | 0.77[199] | 0.85[200] | 0.24[201] | 0.29[202] | -0.15[203] |
30 | PLIN3 | Perilipin-3 | [204] | 1.84[205] | 1.62[206] | 1.10[207] | 0.99[208] | 0.38[209] | 0.08[210] |
31 | MAP1LC3 | Microtubule-associated proteins 1A/1B light chain 3B | [211] | 1.58[212] | 1.24[213] | 0.21[214] | 0.96[215] | 1.57[216] | 0.71[217] |
32 | UBE2N | Ubiquitin-conjugating enzyme E2 N | [218] | 1.54[219] | 1.95[220] | 0.99[221] | 1.13[222] | 1.02[223] | 0.54[224] |
33 | MFN2 | Mitofusin-2 | [225] | 1.55[226] | 2.37[227] | 1.50[228] | 1.69[229] | 1.64[230] | 2.34[231] |
34 | PRKAG1 | 5'-AMP-activated protein kinase subunit gamma-1 | [232] | -0.56[233] | -0.10[234] | 0.24[235] | 0.47[236] | 0.18[237] | -0.39[238] |
35 | DYNC1I2 | Cytoplasmic dynein 1 intermediate chain 2 | [239] | 1.28[240] | 1.67[241] | 1.68[242] | 1.61[243] | 1.26[244] | 0.68[245] |
36 | DYNC1LI2 | Cytoplasmic dynein 1 light intermediate chain 2 | [246] | 1.41[247] | 1.58[248] | 1.30[249] | 1.97[250] | 2.23[251] | 1.59[252] |
37 | NBR1 | Next to BRCA1 gene 1 protein | [253] | 1.52[254] | 2.54[255] | 3.11[256] | 1.77[257] | 1.62[258] | 2.39[259] |
38 | PRKAG2 | 5'-AMP-activated protein kinase subunit gamma-2 | [260] | -3.20[261] | -8.37[262] | -1.72[263] | -0.93[264] | -0.79[265] | 0.79[266] |
39 | EPAS1 | Endothelial PAS domain-containing protein 1 | [267] | 3.56[268] | 2.71[269] | 2.58[270] | 0.24[271] | 3.26[272] | 3.19[273] |
40 | HSF1 | Heat shock factor protein 1 | [274] | 1.21[275] | 0.72[276] | 1.19[277] | 1.33[278] | 0.91[279] | 0.42[280] |
41 | DYNC1LI1 | Cytoplasmic dynein 1 light intermediate chain 1 | [281] | 0.28[282] | 0.46[283] | 1.67[284] | 0.06[285] | 0.69[286] | 0.24[287] |
42 | TUBB3 | Tubulin beta-3 chain | [288] | 3.22[289] | 2.09[290] | -1.86[291] | 1.84[292] | -1.28[293] | -6.51[294] |
43 | TUBB6 | Tubulin beta-6 chain | [295] | 1.65[296] | -0.49[297] | 1.33[298] | 2.54[299] | 2.87[300] | -0.41[301] |
44 | PGAM5 | Serine/threonine-protein phosphatase PGAM5, mitochondrial | [302] | 1.72[303] | 1.77[304] | 1.45[305] | 0.78[306] | 0.90[307] | 1.01[308] |
45 | DYNC1H1 | Cytoplasmic dynein 1 heavy chain 1 | [309] | 4.42[310] | 2.95[311] | 3.97[312] | 4.47[313] | 4.48[314] | 4.45[315] |
46 | PEX5 | Peroxisomal targeting signal 1 receptor | [316] | 1.12[317] | 1.05[318] | 1.68[319] | -0.27[320] | 0.65[321] | 1.21[322] |
47 | CSNK2A2 | Casein kinase II subunit alpha' | [323] | 1.06[324] | 1.05[325] | 1.26[326] | 0.40[327] | 0.60[328] | -0.95[329] |
48 | PRKAB2 | 5'-AMP-activated protein kinase subunit beta-2 | [330] | 1.74[331] | 2.86[332] | 3.18[333] | 1.84[334] | 0.81[335] | 2.67[336] |
49 | MAP1LC3 | Microtubule-associated proteins 1A/1B light chain 3A | [337] | -8.18[338] | -9.70[339] | -8.86[340] | -2.43[341] | -0.48[342] | 0.32[343] |
50 | HDAC6 | Histone deacetylase 6 | [344] | 1.51[345] | 2.39[346] | 2.69[347] | 1.09[348] | 0.56[349] | 3.42[350] |
51 | ATG5 | Autophagy protein 5 | [351] | 0.63[352] | 1.59[353] | 1.47[354] | 1.59[355] | 1.33[356] | 2.10[357] |
52 | TUBB2B | Tubulin beta-2B chain | [358] | 1.52[359] | 0.33[360] | 0.51[361] | 0.38[362] | -3.54[363] | -2.95[364] |
53 | MFN1 | Mitofusin-1 | [365] | 1.01[366] | 1.62[367] | 1.74[368] | 1.70[369] | 1.66[370] | 2.17[371] |
54 | PRKAB1 | 5'-AMP-activated protein kinase subunit beta-1 | [372] | 1.56[373] | 2.03[374] | 1.39[375] | 0.75[376] | 0.85[377] | 1.26[378] |
55 | ATG12 | Ubiquitin-like protein ATG12 | [379] | 1.29[380] | 2.12[381] | 2.26[382] | 2.27[383] | 2.05[384] | 2.70[385] |
56 | SRC | Proto-oncogene tyrosine-protein kinase Src | [386] | 3.88[387] | 3.80[388] | 3.01[389] | 3.21[390] | 2.38[391] | 0.41[392] |
57 | FUNDC1 | FUN14 domain-containing protein 1 | [393] | 0.47[394] | 0.72[395] | 1.33[396] | 1.08[397] | 1.23[398] | -0.11[399] |
58 | TUBA1A | Tubulin alpha-1A chain | [400] | 3.02[401] | -0.42[402] | -3.41[403] | 4.89[404] | 2.42[405] | 1.26[406] |
59 | ULK1 | Serine/threonine-protein kinase ULK1 | [407] | 2.16[408] | 2.38[409] | 3.79[410] | 2.79[411] | 2.13[412] | 3.15[413] |
60 | IFT88 | Intraflagellar transport protein 88 homolog | [414] | -0.12[415] | 1.43[416] | 1.20[417] | 1.01[418] | 0.44[419] | 2.53[420] |
61 | USP30 | Ubiquitin carboxyl-terminal hydrolase 30 | [421] | 0.41[422] | 1.56[423] | 1.74[424] | 0.93[425] | 0.37[426] | 2.59[427] |
62 | ARL13B | ADP-ribosylation factor-like protein 13B | [428] | 0.59[429] | 1.66[430] | 2.54[431] | 1.63[432] | 2.32[433] | 2.13[434] |
63 | ATM | Serine-protein kinase ATM | [435] | 3.88[436] | 5.42[437] | 5.36[438] | 4.97[439] | 4.45[440] | 6.25[441] |
64 | TUBA8 | Tubulin alpha-8 chain | [442] | -2.58[443] | -1.33[444] | -0.47[445] | -1.24[446] | -1.87[447] | 0.54[448] |
65 | PCNT | Pericentrin | [449] | 3.54[450] | 3.91[451] | 3.55[452] | 4.27[453] | 4.09[454] | 5.11[455] |
66 | PRKAA2 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | [456] | 3.89[457] | 4.27[458] | 4.51[459] | 3.85[460] | 1.89[461] | 3.11[462] |
67 | DYNC1I1 | Cytoplasmic dynein 1 intermediate chain 1 | [463] | -3.81[464] | -6.38[465] | 2.14[466] | 1.46[467] | -1.82[468] | -0.08[469] |
68 | TUBB8 | Tubulin beta-8 chain | [470] | 1.43[471] | 0.32[472] | 2.99[473] | -0.01[474] | -3.88[475] | -3.47[476] |
69 | TUBA3D | [477] | -1.14[478] | -0.47[479] | -1.11[480] | 0.33[481] | -0.97[482] | 1.27[483] | |
70 | TUBB1 | Tubulin beta-1 chain | [484] | 5.43[485] | 7.22[486] | 3.26[487] | 3.61[488] | 2.28[489] | 4.82[490] |
71 | TUBB4A | Tubulin beta-4A chain | [491] | 2.68[492] | -1.51[493] | 5.23[494] | 4.44[495] | 3.01[496] | 3.11[497] |
72 | TUBA3E | Tubulin alpha-3E chain | [498] | [499] | -3.99[500] | -3.55[501] | -3.87[502] | -1.51[503] | 0.83[504] |
73 | TUBA3C | Tubulin alpha-3C/D chain | [505] | [506] | -3.47[507] | [508] | 2.00[509] | -4.38[510] | -2.98[511] |
74 | CFTR | Cystic fibrosis transmembrane conductance regulator | [512] | -1.32[513] | -1.90[514] | 1.86[515] | 4.64[516] | -2.96[517] | 8.42[518] |
75 | PRKAG3 | 5'-AMP-activated protein kinase subunit gamma-3 | [519] | -0.89[520] | [521] | -1.07[522] | -0.21[523] | [524] | 4.38[525] |
76 | TUBA4B | Putative tubulin-like protein alpha-4B | [526] | [527] | [528] | [529] | [530] | [531] | [532] |
77 | TUBAL3 | Tubulin alpha chain-like 3 | [533] | [534] | [535] | [536] | [537] | [538] | [539] |
78 | TOMM70 | Mitochondrial import receptor subunit TOM70 | [540] | [541] | [542] | [543] | [544] | [545] | [546] |
79 | MTERF3 | Transcription termination factor 3, mitochondrial | [547] | [548] | [549] | [550] | [551] | [552] | [553] |
80 | TUBB8B | [554] | [555] | [556] | [557] | [558] | [559] | [560] | |
81 | CETN1 | Centrin-1 | [561] | [562] | [563] | [564] | [565] | [566] | [567] |
82 | PRKN | E3 ubiquitin-protein ligase parkin | [568] | [569] | [570] | [571] | [572] | [573] | [574] |