REACTOME_ATF6_ATF6_ALPHA_ACTIVATES_CHAPERONE_GENES Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CALR Calreticulin [1] -0.02[2] -0.99[3] -0.93[4] -0.54[5] -0.41[6] -0.51[7]
2 HSP90B1 Endoplasmin [8] -0.34[9] 0.80[10] 0.07[11] 0.73[12] 0.48[13] 0.45[14]
3 HSPA5 78 kDa glucose-regulated protein [15] 0.50[16] 0.06[17] -0.37[18] 0.29[19] 0.21[20] 0.15[21]
4 ATF4 Cyclic AMP-dependent transcription factor ATF-4 [22] -0.22[23] 0.38[24] 0.59[25] -1.43[26] -0.16[27] -1.73[28]
5 XBP1 X-box-binding protein 1 [29] -0.59[30] -0.82[31] 1.17[32] -1.30[33] -1.75[34] 0.86[35]
6 DDIT3 DNA damage-inducible transcript 3 protein [36] -1.03[37] -0.76[38] -0.63[39] -0.51[40] 0.19[41] -1.70[42]
7 NFYC Nuclear transcription factor Y subunit gamma [43] 0.65[44] 0.01[45] 0.40[46] 1.34[47] 0.47[48] 0.05[49]
8 NFYB Nuclear transcription factor Y subunit beta [50] 0.31[51] 1.42[52] 1.10[53] 1.99[54] 2.15[55] 0.48[56]
9 ATF6 Cyclic AMP-dependent transcription factor ATF-6 alpha [57] 2.69[58] 2.23[59] 2.14[60] 4.05[61] 3.97[62] 3.18[63]
10 NFYA Nuclear transcription factor Y subunit alpha [64] 2.50[65] 2.21[66] 2.41[67] 3.03[68] 2.31[69] 0.95[70]
[1]
ref_hepatocyte CALR
Mean 617
Standard deviation 2.8e+02
Values 7.7e+02 4.7e+02 3.5e+02 1e+03 4.6e+02
[2]
HepG2 CALR
Mean 698
Standard deviation 0.66
Values 7e+02 7e+02
[3]
HepG2.C3A CALR
Mean 448
Standard deviation 1.7e+02
Values 3.3e+02 5.7e+02
[4]
HuH.7 CALR
Mean 360
Standard deviation 34
Values 3.3e+02 3.5e+02 4e+02
[5]
SNU475 CALR
Mean 258
Standard deviation 1.5e+02
Values 3.6e+02 1.6e+02
[6]
THLE CALR
Mean 356
Standard deviation 52
Values 3.2e+02 3.9e+02
[7]
liver CALR
Mean 440
Standard deviation 89
Values 4e+02 3.7e+02 5.7e+02 4.2e+02
[8]
ref_hepatocyte HSP90B1
Mean 367
Standard deviation 3.6e+02
Values 3.1e+02 1.4e+02 1.2e+02 9.9e+02 2.8e+02
[9]
HepG2 HSP90B1
Mean 332
Standard deviation 69
Values 2.8e+02 3.8e+02
[10]
HepG2.C3A HSP90B1
Mean 925
Standard deviation 72
Values 8.7e+02 9.8e+02
[11]
HuH.7 HSP90B1
Mean 428
Standard deviation 74
Values 3.7e+02 5.1e+02 4e+02
[12]
SNU475 HSP90B1
Mean 369
Standard deviation 1.2e+02
Values 4.5e+02 2.9e+02
[13]
THLE HSP90B1
Mean 393
Standard deviation 13
Values 3.8e+02 4e+02
[14]
liver HSP90B1
Mean 511
Standard deviation 1.5e+02
Values 4e+02 6e+02 6.8e+02 3.6e+02
[15]
ref_hepatocyte HSPA5
Mean 323
Standard deviation 1.8e+02
Values 2.1e+02 1.7e+02 4.7e+02 5.6e+02 2.1e+02
[16]
HepG2 HSPA5
Mean 522
Standard deviation 17
Values 5.1e+02 5.3e+02
[17]
HepG2.C3A HSPA5
Mean 488
Standard deviation 22
Values 5e+02 4.7e+02
[18]
HuH.7 HSPA5
Mean 279
Standard deviation 1e+02
Values 2.1e+02 4e+02 2.3e+02
[19]
SNU475 HSPA5
Mean 240
Standard deviation 1.2e+02
Values 3.2e+02 1.6e+02
[20]
THLE HSPA5
Mean 287
Standard deviation 62
Values 2.4e+02 3.3e+02
[21]
liver HSPA5
Mean 365
Standard deviation 1.6e+02
Values 2.5e+02 3.1e+02 6.1e+02 2.9e+02
[22]
ref_hepatocyte ATF4
Mean 212
Standard deviation 1.7e+02
Values 76 1.1e+02 4.8e+02 2.7e+02 1.3e+02
[23]
HepG2 ATF4
Mean 208
Standard deviation 25
Values 2.3e+02 1.9e+02
[24]
HepG2.C3A ATF4
Mean 397
Standard deviation 1.4e+02
Values 4.9e+02 3e+02
[25]
HuH.7 ATF4
Mean 356
Standard deviation 84
Values 3.1e+02 3.1e+02 4.5e+02
[26]
SNU475 ATF4
Mean 47.8
Standard deviation 2.6
Values 50 46
[27]
THLE ATF4
Mean 145
Standard deviation 1.3
Values 1.5e+02 1.4e+02
[28]
liver ATF4
Mean 64.9
Standard deviation 27
Values 1e+02 44 68 46
[29]
ref_hepatocyte XBP1
Mean 168
Standard deviation 1.5e+02
Values 56 56 60 2.9e+02 3.8e+02
[30]
HepG2 XBP1
Mean 127
Standard deviation 20
Values 1.1e+02 1.4e+02
[31]
HepG2.C3A XBP1
Mean 137
Standard deviation 17
Values 1.5e+02 1.3e+02
[32]
HuH.7 XBP1
Mean 422
Standard deviation 17
Values 4e+02 4.3e+02 4.3e+02
[33]
SNU475 XBP1
Mean 41.4
Standard deviation 13
Values 51 32
[34]
THLE XBP1
Mean 38.5
Standard deviation 6.1
Values 34 43
[35]
liver XBP1
Mean 311
Standard deviation 1.9e+02
Values 5.8e+02 1.8e+02 3e+02 1.9e+02
[36]
ref_hepatocyte DDIT3
Mean 23.4
Standard deviation 23
Values 7.5 13 17 64 15
[37]
HepG2 DDIT3
Mean 13.1
Standard deviation 8.7
Values 19 7
[38]
HepG2.C3A DDIT3
Mean 19.9
Standard deviation 9
Values 26 14
[39]
HuH.7 DDIT3
Mean 16.9
Standard deviation 6.4
Values 10 23 18
[40]
SNU475 DDIT3
Mean 10
Standard deviation 0.8
Values 9.5 11
[41]
THLE DDIT3
Mean 20.6
Standard deviation 4
Values 23 18
[42]
liver DDIT3
Mean 7.31
Standard deviation 5.6
Values 12 2.7 12 2.3
[43]
ref_hepatocyte NFYC
Mean 10
Standard deviation 3.8
Values 16 5.5 8.7 11 9.2
[44]
HepG2 NFYC
Mean 18
Standard deviation 1.9
Values 17 19
[45]
HepG2.C3A NFYC
Mean 14.6
Standard deviation 0.89
Values 15 14
[46]
HuH.7 NFYC
Mean 14.8
Standard deviation 0.42
Values 15 15 15
[47]
SNU475 NFYC
Mean 15.5
Standard deviation 1
Values 16 15
[48]
THLE NFYC
Mean 10.7
Standard deviation 1.4
Values 9.7 12
[49]
liver NFYC
Mean 10.6
Standard deviation 6.2
Values 19 5 12 6.6
[50]
ref_hepatocyte NFYB
Mean 4.68
Standard deviation 1.8
Values 4.3 7.4 2.9 3.6 5.2
[51]
HepG2 NFYB
Mean 6.64
Standard deviation 1.1
Values 5.8 7.5
[52]
HepG2.C3A NFYB
Mean 18
Standard deviation 5.3
Values 14 22
[53]
HuH.7 NFYB
Mean 11.1
Standard deviation 3
Values 12 7.7 13
[54]
SNU475 NFYB
Mean 11.3
Standard deviation 0.64
Values 12 11
[55]
THLE NFYB
Mean 16
Standard deviation 0.47
Values 16 16
[56]
liver NFYB
Mean 6.62
Standard deviation 2.1
Values 9.6 4.9 6.5 5.4
[57]
ref_hepatocyte ATF6
Mean 4.13
Standard deviation 1.9
Values 1.9 3 5.6 6.5 3.6
[58]
HepG2 ATF6
Mean 30.5
Standard deviation 4.7
Values 27 34
[59]
HepG2.C3A ATF6
Mean 27.9
Standard deviation 2.3
Values 26 29
[60]
HuH.7 ATF6
Mean 20.2
Standard deviation 4.2
Values 21 24 16
[61]
SNU475 ATF6
Mean 41.5
Standard deviation 2.3
Values 43 40
[62]
THLE ATF6
Mean 49.9
Standard deviation 3.5
Values 47 52
[63]
liver ATF6
Mean 38.1
Standard deviation 7
Values 35 48 33 36
[64]
ref_hepatocyte NFYA
Mean 3.88
Standard deviation 3.9
Values 11 3.4 1.1 2.2 1.9
[65]
HepG2 NFYA
Mean 25.1
Standard deviation 8.5
Values 19 31
[66]
HepG2.C3A NFYA
Mean 26
Standard deviation 6.6
Values 21 31
[67]
HuH.7 NFYA
Mean 22.9
Standard deviation 2.6
Values 26 20 23
[68]
SNU475 NFYA
Mean 19.3
Standard deviation 0.21
Values 19 19
[69]
THLE NFYA
Mean 14.8
Standard deviation 1.4
Values 14 16
[70]
liver NFYA
Mean 7.61
Standard deviation 3.9
Values 3.6 9.7 5.2 12