REACTOME_RUNX3_REGULATES_NOTCH_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 SNW1 SNW domain-containing protein 1 [1] -2.58[2] -1.82[3] -2.07[4] -1.17[5] -1.24[6] -2.59[7]
2 HES1 Transcription factor HES-1 [8] -2.01[9] -3.92[10] -1.95[11] -2.31[12] -2.96[13] -2.35[14]
3 KAT2A Histone acetyltransferase KAT2A [15] 0.45[16] 0.90[17] -0.26[18] 0.09[19] 0.12[20] -0.67[21]
4 RBPJ Recombining binding protein suppressor of hairless [22] -0.24[23] 0.93[24] 1.65[25] 0.98[26] 1.09[27] 0.90[28]
5 KAT2B Histone acetyltransferase KAT2B [29] -3.63[30] -4.15[31] -2.07[32] -1.10[33] -0.50[34] 0.83[35]
6 JAG1 Protein jagged-1 [36] 3.20[37] 2.38[38] 1.57[39] 0.48[40] -0.70[41] 0.09[42]
7 EP300 Histone acetyltransferase p300 [43] 1.14[44] 1.33[45] 1.94[46] 1.53[47] 1.77[48] 1.80[49]
8 MAML1 Mastermind-like protein 1 [50] 0.53[51] 1.09[52] 1.35[53] 1.20[54] 1.52[55] 0.13[56]
9 CREBBP CREB-binding protein [57] 1.32[58] 1.13[59] 1.46[60] 1.72[61] 1.91[62] 2.28[63]
10 MAMLD1 Mastermind-like domain-containing protein 1 [64] -3.48[65] -9.38[66] -3.41[67] 0.01[68] 0.02[69] -1.29[70]
11 NOTCH1 Neurogenic locus notch homolog protein 1 [71] 0.32[72] -0.24[73] 0.81[74] 1.55[75] 2.08[76] 3.68[77]
12 MAML3 Mastermind-like protein 3 [78] -1.96[79] -0.63[80] 2.12[81] 0.36[82] -0.84[83] 2.54[84]
13 MAML2 Mastermind-like protein 2 [85] 1.91[86] 3.12[87] -3.72[88] 3.74[89] 2.79[90] 1.41[91]
14 RUNX3 Runt-related transcription factor 3 [92] -0.82[93] -1.20[94] 1.51[95] 2.53[96] -2.48[97] 0.41[98]
[1]
ref_hepatocyte SNW1
Mean 24.9
Standard deviation 12
Values 34 38 27 15 9.7
[2]
HepG2 SNW1
Mean 27.5
Standard deviation 2.9
Values 25 29
[3]
HepG2.C3A SNW1
Mean 27.5
Standard deviation 0.76
Values 27 28
[4]
HuH.7 SNW1
Mean 26.8
Standard deviation 1.3
Values 26 26 28
[5]
SNU475 SNW1
Mean 41.5
Standard deviation 3.1
Values 39 44
[6]
THLE SNW1
Mean 39.4
Standard deviation 2.3
Values 38 41
[7]
liver SNW1
Mean 11.4
Standard deviation 4.1
Values 14 9.2 15 6.8
[8]
ref_hepatocyte HES1
Mean 7.15
Standard deviation 5.3
Values 9.1 1 3.7 15 7
[9]
HepG2 HES1
Mean 11.7
Standard deviation 5.7
Values 16 7.7
[10]
HepG2.C3A HES1
Mean 1.84
Standard deviation 0.56
Values 2.2 1.4
[11]
HuH.7 HES1
Mean 8.41
Standard deviation 1.4
Values 6.9 8.7 9.7
[12]
SNU475 HES1
Mean 5.42
Standard deviation 0.41
Values 5.7 5.1
[13]
THLE HES1
Mean 3.42
Standard deviation 0.023
Values 3.4 3.4
[14]
liver HES1
Mean 3.86
Standard deviation 1.7
Values 6.2 3 4.1 2.2
[15]
ref_hepatocyte KAT2A
Mean 4.96
Standard deviation 1.9
Values 2.4 3.8 6.7 6.8 5
[16]
HepG2 KAT2A
Mean 44.7
Standard deviation 6.9
Values 40 50
[17]
HepG2.C3A KAT2A
Mean 36.2
Standard deviation 5
Values 40 33
[18]
HuH.7 KAT2A
Mean 18.7
Standard deviation 8
Values 18 11 27
[19]
SNU475 KAT2A
Mean 19.9
Standard deviation 2.9
Values 18 22
[20]
THLE KAT2A
Mean 20.1
Standard deviation 3.5
Values 23 18
[21]
liver KAT2A
Mean 8.57
Standard deviation 1.6
Values 9.3 6.8 11 7.7
[22]
ref_hepatocyte RBPJ
Mean 3.53
Standard deviation 1.3
Values 5.4 3.5 3.8 2.1 2.8
[23]
HepG2 RBPJ
Mean 19.7
Standard deviation 8.2
Values 14 26
[24]
HepG2.C3A RBPJ
Mean 26.2
Standard deviation 1.4
Values 25 27
[25]
HuH.7 RBPJ
Mean 50.4
Standard deviation 6.7
Values 58 49 45
[26]
SNU475 RBPJ
Mean 26.3
Standard deviation 0.26
Values 26 26
[27]
THLE RBPJ
Mean 28.1
Standard deviation 3.7
Values 26 31
[28]
liver RBPJ
Mean 18.1
Standard deviation 2.4
Values 21 19 17 16
[29]
ref_hepatocyte KAT2B
Mean 3.02
Standard deviation 2.4
Values 0.53 4.6 0.74 3.2 6.1
[30]
HepG2 KAT2B
Mean 1.62
Standard deviation 1.1
Values 0.84 2.4
[31]
HepG2.C3A KAT2B
Mean 0.662
Standard deviation 0.012
Values 0.67 0.65
[32]
HuH.7 KAT2B
Mean 3.28
Standard deviation 0.41
Values 2.8 3.6 3.4
[33]
SNU475 KAT2B
Mean 5.31
Standard deviation 1.3
Values 6.2 4.4
[34]
THLE KAT2B
Mean 7.98
Standard deviation 1.1
Values 7.2 8.8
[35]
liver KAT2B
Mean 14.8
Standard deviation 5
Values 19 17 7.6 16
[36]
ref_hepatocyte JAG1
Mean 2.61
Standard deviation 3.4
Values 8.4 2.4 1.7 0.3 0.21
[37]
HepG2 JAG1
Mean 158
Standard deviation 86
Values 2.2e+02 97
[38]
HepG2.C3A JAG1
Mean 52.9
Standard deviation 7.2
Values 58 48
[39]
HuH.7 JAG1
Mean 35.1
Standard deviation 12
Values 45 21 39
[40]
SNU475 JAG1
Mean 13.7
Standard deviation 0.39
Values 13 14
[41]
THLE JAG1
Mean 6
Standard deviation 0.4
Values 5.7 6.3
[42]
liver JAG1
Mean 7.68
Standard deviation 5.1
Values 4.1 8.6 3.5 15
[43]
ref_hepatocyte EP300
Mean 2.46
Standard deviation 1.2
Values 3 1.8 4.4 1.4 1.8
[44]
HepG2 EP300
Mean 35.9
Standard deviation 5.7
Values 32 40
[45]
HepG2.C3A EP300
Mean 24.1
Standard deviation 1.4
Values 23 25
[46]
HuH.7 EP300
Mean 43
Standard deviation 15
Values 55 48 26
[47]
SNU475 EP300
Mean 26.9
Standard deviation 1.3
Values 28 26
[48]
THLE EP300
Mean 31.2
Standard deviation 11
Values 23 39
[49]
liver EP300
Mean 23.6
Standard deviation 8
Values 20 27 15 33
[50]
ref_hepatocyte MAML1
Mean 2.18
Standard deviation 1.5
Values 4.8 1.9 2.1 1.1 1
[51]
HepG2 MAML1
Mean 20.9
Standard deviation 0.74
Values 20 21
[52]
HepG2.C3A MAML1
Mean 18.1
Standard deviation 1.4
Values 19 17
[53]
HuH.7 MAML1
Mean 25.3
Standard deviation 3.3
Values 29 23 24
[54]
SNU475 MAML1
Mean 19
Standard deviation 0.56
Values 19 19
[55]
THLE MAML1
Mean 23.3
Standard deviation 2.6
Values 21 25
[56]
liver MAML1
Mean 6.56
Standard deviation 1.8
Values 6 5.9 5.1 9.3
[57]
ref_hepatocyte CREBBP
Mean 1.78
Standard deviation 0.69
Values 1.8 0.72 2.6 1.9 1.9
[58]
HepG2 CREBBP
Mean 29.3
Standard deviation 2.8
Values 27 31
[59]
HepG2.C3A CREBBP
Mean 15.2
Standard deviation 1
Values 16 14
[60]
HuH.7 CREBBP
Mean 22.2
Standard deviation 7.2
Values 28 24 14
[61]
SNU475 CREBBP
Mean 22.1
Standard deviation 0.2
Values 22 22
[62]
THLE CREBBP
Mean 24.9
Standard deviation 7.3
Values 20 30
[63]
liver CREBBP
Mean 23.8
Standard deviation 6
Values 30 21 17 28
[64]
ref_hepatocyte MAMLD1
Mean 0.833
Standard deviation 1.1
Values 0 0.39 2.7 0.16 0.94
[65]
HepG2 MAMLD1
Mean 0.493
Standard deviation 0.22
Values 0.34 0.65
[66]
HepG2.C3A MAMLD1
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[67]
HuH.7 MAMLD1
Mean 0.356
Standard deviation 0.046
Values 0.31 0.35 0.4
[68]
SNU475 MAMLD1
Mean 3.17
Standard deviation 0.79
Values 2.6 3.7
[69]
THLE MAMLD1
Mean 3.14
Standard deviation 0.38
Values 3.4 2.9
[70]
liver MAMLD1
Mean 0.94
Standard deviation 0.39
Values 1.1 0.64 1.4 0.62
[71]
ref_hepatocyte NOTCH1
Mean 0.644
Standard deviation 0.25
Values 0.33 0.55 0.55 0.91 0.89
[72]
HepG2 NOTCH1
Mean 5.33
Standard deviation 3.7
Values 8 2.7
[73]
HepG2.C3A NOTCH1
Mean 2.12
Standard deviation 0.1
Values 2.1 2.2
[74]
HuH.7 NOTCH1
Mean 5.14
Standard deviation 1.4
Values 5.4 6.4 3.6
[75]
SNU475 NOTCH1
Mean 7.09
Standard deviation 0.64
Values 6.6 7.5
[76]
THLE NOTCH1
Mean 10.2
Standard deviation 2.2
Values 8.6 12
[77]
liver NOTCH1
Mean 22.8
Standard deviation 16
Values 10 31 8.8 41
[78]
ref_hepatocyte MAML3
Mean 0.411
Standard deviation 0.24
Values 0 0.58 0.59 0.46 0.43
[79]
HepG2 MAML3
Mean 0.699
Standard deviation 0.024
Values 0.72 0.68
[80]
HepG2.C3A MAML3
Mean 1.04
Standard deviation 0.079
Values 0.98 1.1
[81]
HuH.7 MAML3
Mean 8.13
Standard deviation 2.1
Values 9.1 9.5 5.8
[82]
SNU475 MAML3
Mean 1.99
Standard deviation 0.56
Values 2.4 1.6
[83]
THLE MAML3
Mean 0.858
Standard deviation 0.2
Values 0.72 1
[84]
liver MAML3
Mean 6.6
Standard deviation 2.8
Values 4.4 9.7 4 8.3
[85]
ref_hepatocyte MAML2
Mean 0.226
Standard deviation 0.3
Values 0.69 0 0.36 0 0.089
[86]
HepG2 MAML2
Mean 5.61
Standard deviation 0.32
Values 5.8 5.4
[87]
HepG2.C3A MAML2
Mean 7.69
Standard deviation 1.2
Values 8.6 6.8
[88]
HuH.7 MAML2
Mean 0.0778
Standard deviation 0.056
Values 0.13 0.083 0.019
[89]
SNU475 MAML2
Mean 11.4
Standard deviation 0.01
Values 11 11
[90]
THLE MAML2
Mean 5.83
Standard deviation 0.93
Values 5.2 6.5
[91]
liver MAML2
Mean 1.66
Standard deviation 0.64
Values 1.1 1.9 1.2 2.4
[92]
ref_hepatocyte RUNX3
Mean 0.138
Standard deviation 0.14
Values 0 0 0.16 0.23 0.3
[93]
HepG2 RUNX3
Mean 0.518
Standard deviation 0.51
Values 0.88 0.15
[94]
HepG2.C3A RUNX3
Mean 0.234
Standard deviation 0.013
Values 0.24 0.23
[95]
HuH.7 RUNX3
Mean 1.78
Standard deviation 0.41
Values 2.2 1.6 1.5
[96]
SNU475 RUNX3
Mean 3.01
Standard deviation 0.24
Values 2.8 3.2
[97]
THLE RUNX3
Mean 0.0922
Standard deviation 0.005
Values 0.089 0.096
[98]
liver RUNX3
Mean 0.506
Standard deviation 0.18
Values 0.61 0.46 0.28 0.68