REACTOME_RUNX3_REGULATES_CDKN1A_TRANSCRIPTION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CDKN1A Cyclin-dependent kinase inhibitor 1 [1] -0.55[2] -1.18[3] -3.41[4] -2.76[5] -0.78[6] -1.84[7]
2 SMAD3 Mothers against decapentaplegic homolog 3 [8] 0.54[9] 0.69[10] 1.38[11] 1.02[12] 1.33[13] 0.21[14]
3 TP53 Cellular tumor antigen p53 [15] 0.24[16] 0.57[17] 1.79[18] 0.52[19] -0.39[20] -0.05[21]
4 SMAD4 Mothers against decapentaplegic homolog 4 [22] 0.00[23] 1.39[24] 1.82[25] 1.14[26] 0.93[27] 2.78[28]
5 TGFB1 Transforming growth factor beta-1 [29] 2.08[30] 1.80[31] -0.48[32] 3.06[33] 1.72[34] -1.23[35]
6 ZFHX3 Zinc finger homeobox protein 3 [36] 1.76[37] 2.99[38] 2.99[39] 2.79[40] 1.28[41] 3.81[42]
7 RUNX3 Runt-related transcription factor 3 [43] -0.63[44] -0.85[45] 2.60[46] 2.79[47] -2.97[48] 1.36[49]
[1]
ref_hepatocyte CDKN1A
Mean 40.1
Standard deviation 28
Values 19 48 76 52 5.7
[2]
HepG2 CDKN1A
Mean 158
Standard deviation 49
Values 1.9e+02 1.2e+02
[3]
HepG2.C3A CDKN1A
Mean 53.9
Standard deviation 3.9
Values 51 57
[4]
HuH.7 CDKN1A
Mean 8
Standard deviation 1.9
Values 6.5 10 7.3
[5]
SNU475 CDKN1A
Mean 18.6
Standard deviation 7.8
Values 13 24
[6]
THLE CDKN1A
Mean 122
Standard deviation 11
Values 1.3e+02 1.1e+02
[7]
liver CDKN1A
Mean 16
Standard deviation 8.1
Values 16 6.2 26 16
[8]
ref_hepatocyte SMAD3
Mean 5.99
Standard deviation 4.6
Values 4.8 8.4 13 1.9 2.2
[9]
HepG2 SMAD3
Mean 50.4
Standard deviation 14
Values 60 40
[10]
HepG2.C3A SMAD3
Mean 29.5
Standard deviation 11
Values 37 22
[11]
HuH.7 SMAD3
Mean 33.2
Standard deviation 6.9
Values 31 41 28
[12]
SNU475 SMAD3
Mean 38.2
Standard deviation 2.7
Values 40 36
[13]
THLE SMAD3
Mean 78.9
Standard deviation 8.4
Values 73 85
[14]
liver SMAD3
Mean 9.85
Standard deviation 3
Values 12 7.4 7.1 13
[15]
ref_hepatocyte TP53
Mean 5.28
Standard deviation 0.94
Values 5.5 3.7 6.2 5.5 5.5
[16]
HepG2 TP53
Mean 36.3
Standard deviation 0.12
Values 36 36
[17]
HepG2.C3A TP53
Mean 23.9
Standard deviation 1.8
Values 23 25
[18]
HuH.7 TP53
Mean 38.7
Standard deviation 16
Values 50 20 46
[19]
SNU475 TP53
Mean 23.7
Standard deviation 6.7
Values 28 19
[20]
THLE TP53
Mean 21.1
Standard deviation 6.6
Values 16 26
[21]
liver TP53
Mean 7.29
Standard deviation 2.3
Values 9 5 9.5 5.6
[22]
ref_hepatocyte SMAD4
Mean 3.16
Standard deviation 0.71
Values 2.9 2.8 4.2 2.4 3.4
[23]
HepG2 SMAD4
Mean 18.3
Standard deviation 3.2
Values 16 21
[24]
HepG2.C3A SMAD4
Mean 25.2
Standard deviation 3
Values 27 23
[25]
HuH.7 SMAD4
Mean 23.6
Standard deviation 3.4
Values 24 27 20
[26]
SNU475 SMAD4
Mean 21.8
Standard deviation 2.7
Values 24 20
[27]
THLE SMAD4
Mean 31.4
Standard deviation 1.4
Values 30 32
[28]
liver SMAD4
Mean 31
Standard deviation 13
Values 23 40 16 44
[29]
ref_hepatocyte TGFB1
Mean 2.22
Standard deviation 1.8
Values 5.3 1.3 0.92 1.3 2.3
[30]
HepG2 TGFB1
Mean 54.4
Standard deviation 32
Values 77 32
[31]
HepG2.C3A TGFB1
Mean 23.6
Standard deviation 8.3
Values 29 18
[32]
HuH.7 TGFB1
Mean 3.37
Standard deviation 1.4
Values 4.5 1.8 3.7
[33]
SNU475 TGFB1
Mean 58.3
Standard deviation 7.8
Values 64 53
[34]
THLE TGFB1
Mean 38.3
Standard deviation 9.8
Values 31 45
[35]
liver TGFB1
Mean 1.34
Standard deviation 0.71
Values 1.1 1.4 0.62 2.3
[36]
ref_hepatocyte ZFHX3
Mean 0.817
Standard deviation 0.71
Values 2.1 0.31 0.75 0.54 0.42
[37]
HepG2 ZFHX3
Mean 16
Standard deviation 4.7
Values 13 19
[38]
HepG2.C3A ZFHX3
Mean 19.7
Standard deviation 0.045
Values 20 20
[39]
HuH.7 ZFHX3
Mean 13.8
Standard deviation 5.4
Values 16 18 7.6
[40]
SNU475 ZFHX3
Mean 17.8
Standard deviation 0.0096
Values 18 18
[41]
THLE ZFHX3
Mean 10.4
Standard deviation 0.7
Values 9.9 11
[42]
liver ZFHX3
Mean 16.3
Standard deviation 3.2
Values 16 19 12 18
[43]
ref_hepatocyte RUNX3
Mean 0.138
Standard deviation 0.14
Values 0 0 0.16 0.23 0.3
[44]
HepG2 RUNX3
Mean 0.518
Standard deviation 0.51
Values 0.88 0.15
[45]
HepG2.C3A RUNX3
Mean 0.234
Standard deviation 0.013
Values 0.24 0.23
[46]
HuH.7 RUNX3
Mean 1.78
Standard deviation 0.41
Values 2.2 1.6 1.5
[47]
SNU475 RUNX3
Mean 3.01
Standard deviation 0.24
Values 2.8 3.2
[48]
THLE RUNX3
Mean 0.0922
Standard deviation 0.005
Values 0.089 0.096
[49]
liver RUNX3
Mean 0.506
Standard deviation 0.18
Values 0.61 0.46 0.28 0.68