REACTOME_RUNX2_REGULATES_BONE_DEVELOPMENT | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | YES1 | Tyrosine-protein kinase Yes | [1] | -2.03[2] | -0.55[3] | -0.31[4] | -1.07[5] | -1.85[6] | -1.22[7] |
2 | HDAC3 | Histone deacetylase 3 | [8] | -0.68[9] | -0.64[10] | -0.82[11] | -1.57[12] | -1.65[13] | -1.74[14] |
3 | YAP1 | Transcriptional coactivator YAP1 | [15] | 0.80[16] | 0.24[17] | -0.11[18] | 0.76[19] | -0.06[20] | -0.99[21] |
4 | MAPK1 | Mitogen-activated protein kinase 1 | [22] | 0.54[23] | 0.67[24] | 0.51[25] | 0.33[26] | -0.26[27] | 0.44[28] |
5 | CBFB | Core-binding factor subunit beta | [29] | -0.62[30] | -0.03[31] | -0.97[32] | -0.69[33] | -0.50[34] | -1.72[35] |
6 | HES1 | Transcription factor HES-1 | [36] | -1.60[37] | -4.11[38] | -1.85[39] | -2.80[40] | -3.86[41] | -2.74[42] |
7 | HDAC6 | Histone deacetylase 6 | [43] | -0.51[44] | 0.42[45] | 0.53[46] | -1.24[47] | -2.00[48] | 0.82[49] |
8 | SMAD1 | Mothers against decapentaplegic homolog 1 | [50] | -2.22[51] | -1.97[52] | -1.66[53] | -2.25[54] | -1.93[55] | -0.71[56] |
9 | WWTR1 | WW domain-containing transcription regulator protein 1 | [57] | 0.73[58] | 0.30[59] | -0.67[60] | 0.79[61] | -0.13[62] | -0.60[63] |
10 | AR | Androgen receptor | [64] | -11.62[65] | -10.95[66] | -12.78[67] | -3.27[68] | -6.54[69] | 2.31[70] |
11 | MAPK3 | Mitogen-activated protein kinase 3 | [71] | 0.68[72] | 0.72[73] | 0.77[74] | -1.10[75] | -1.31[76] | -2.38[77] |
12 | RBM14 | RNA-binding protein 14 | [78] | 0.40[79] | -0.05[80] | 0.56[81] | -0.06[82] | -0.43[83] | -0.07[84] |
13 | ABL1 | Tyrosine-protein kinase ABL1 | [85] | 1.06[86] | 0.44[87] | 1.25[88] | 0.55[89] | 1.00[90] | -0.40[91] |
14 | SRC | Proto-oncogene tyrosine-protein kinase Src | [92] | 1.86[93] | 1.83[94] | 0.84[95] | 0.88[96] | -0.18[97] | -2.19[98] |
15 | SMAD4 | Mothers against decapentaplegic homolog 4 | [99] | 0.23[100] | 0.84[101] | 0.83[102] | 0.39[103] | 0.52[104] | 1.45[105] |
16 | RB1 | Retinoblastoma-associated protein | [106] | 0.05[107] | 0.54[108] | 1.12[109] | 0.75[110] | 0.84[111] | 0.14[112] |
17 | MAF | Transcription factor Maf | [113] | -4.05[114] | -7.11[115] | 0.03[116] | -1.37[117] | -2.55[118] | 1.07[119] |
18 | SMAD6 | Mothers against decapentaplegic homolog 6 | [120] | 0.25[121] | -1.51[122] | -1.07[123] | -0.07[124] | -1.86[125] | -0.48[126] |
19 | HEY1 | Hairy/enhancer-of-split related with YRPW motif protein 1 | [127] | 0.47[128] | -1.08[129] | -1.00[130] | -2.02[131] | -3.45[132] | -1.29[133] |
20 | SATB2 | DNA-binding protein SATB2 | [134] | 0.05[135] | 1.51[136] | 1.12[137] | -0.43[138] | 0.35[139] | -0.47[140] |
21 | HEY2 | Hairy/enhancer-of-split related with YRPW motif protein 2 | [141] | -4.89[142] | -6.70[143] | -6.78[144] | -5.39[145] | -8.45[146] | -0.58[147] |
22 | HDAC4 | Histone deacetylase 4 | [148] | 2.30[149] | 2.12[150] | 1.91[151] | 1.18[152] | 1.26[153] | 2.04[154] |
23 | COL1A1 | Collagen alpha-1(I) chain | [155] | 3.57[156] | -3.95[157] | -2.12[158] | 5.48[159] | 6.79[160] | 5.01[161] |
24 | IHH | Indian hedgehog protein | [162] | -0.11[163] | -2.07[164] | 3.75[165] | -5.82[166] | -6.92[167] | -1.24[168] |
25 | RUNX2 | Runt-related transcription factor 2 | [169] | -2.01[170] | -2.38[171] | 2.70[172] | 5.60[173] | 7.32[174] | 2.28[175] |
26 | GLI2 | Zinc finger protein GLI2 | [176] | -0.52[177] | -4.08[178] | -2.33[179] | 6.95[180] | 5.89[181] | 1.54[182] |
27 | GLI3 | Transcriptional activator GLI3 | [183] | -2.39[184] | [185] | -1.43[186] | 7.41[187] | 5.54[188] | 2.81[189] |
28 | ZNF521 | Zinc finger protein 521 | [190] | -0.85[191] | [192] | [193] | 2.77[194] | -0.66[195] | 5.10[196] |
29 | BGLAP | Osteocalcin | [197] | [198] | [199] | [200] | [201] | [202] | [203] |
30 | UCMA | Unique cartilage matrix-associated protein | [204] | [205] | [206] | [207] | [208] | [209] | [210] |
31 | SP7 | Transcription factor Sp7 | [211] | [212] | [213] | [214] | [215] | [216] | [217] |