REACTOME_RUNX1_AND_FOXP3_CONTROL_THE_DEVELOPMENT_OF_REGULATORY_T_LYMPHOCYTES_TREGS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CBFB Core-binding factor subunit beta [1] -0.22[2] 0.01[3] -0.21[4] -0.35[5] -0.09[6] -0.84[7]
2 RUNX1 Runt-related transcription factor 1 [8] 0.44[9] -1.15[10] -0.30[11] 0.99[12] 0.54[13] -1.10[14]
3 NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 [15] 1.82[16] 2.70[17] 2.86[18] -1.01[19] -0.21[20] 2.83[21]
4 IFNG Interferon gamma [22] [23] [24] [25] -1.88[26] [27] -2.75[28]
5 FOXP3 Forkhead box protein P3 [29] -3.98[30] -4.25[31] -5.08[32] -3.50[33] -5.17[34] -0.23[35]
6 IL2RA Interleukin-2 receptor subunit alpha [36] [37] -6.73[38] [39] -5.79[40] -7.86[41] 0.08[42]
7 CR1 Complement receptor type 1 [43] -3.33[44] -3.15[45] -2.03[46] -3.30[47] -4.03[48] 4.59[49]
8 TNFRSF18 Tumor necrosis factor receptor superfamily member 18 [50] -0.37[51] -1.42[52] -3.89[53] -1.50[54] [55] -0.20[56]
9 IL2 Interleukin-2 [57] [58] [59] [60] [61] [62] [63]
10 CTLA4 Cytotoxic T-lymphocyte protein 4 [64] [65] [66] [67] [68] [69] [70]
[1]
ref_hepatocyte CBFB
Mean 7.69
Standard deviation 6.8
Values 17 12 3.4 2.3 3.1
[2]
HepG2 CBFB
Mean 24.8
Standard deviation 2.9
Values 23 27
[3]
HepG2.C3A CBFB
Mean 33.6
Standard deviation 8
Values 28 39
[4]
HuH.7 CBFB
Mean 16.5
Standard deviation 4.3
Values 19 12 19
[5]
SNU475 CBFB
Mean 25.2
Standard deviation 0.84
Values 26 25
[6]
THLE CBFB
Mean 37.8
Standard deviation 4.4
Values 35 41
[7]
liver CBFB
Mean 8.39
Standard deviation 1.4
Values 7.5 9 10 7
[8]
ref_hepatocyte RUNX1
Mean 2.34
Standard deviation 3.6
Values 0.45 0.91 8.7 1.1 0.48
[9]
HepG2 RUNX1
Mean 11.9
Standard deviation 4.1
Values 15 9.1
[10]
HepG2.C3A RUNX1
Mean 4.58
Standard deviation 0.1
Values 4.5 4.7
[11]
HuH.7 RUNX1
Mean 4.74
Standard deviation 1.4
Values 5.9 3.1 5.2
[12]
SNU475 RUNX1
Mean 19.5
Standard deviation 1.9
Values 18 21
[13]
THLE RUNX1
Mean 17.8
Standard deviation 0.32
Values 18 18
[14]
liver RUNX1
Mean 2.13
Standard deviation 1
Values 1.6 1.8 1.5 3.7
[15]
ref_hepatocyte NFATC2
Mean 0.322
Standard deviation 0.29
Values 0.36 0.15 0.8 0.095 0.21
[16]
HepG2 NFATC2
Mean 4.27
Standard deviation 1.6
Values 3.1 5.4
[17]
HepG2.C3A NFATC2
Mean 9.11
Standard deviation 2.4
Values 11 7.4
[18]
HuH.7 NFATC2
Mean 5.8
Standard deviation 2.3
Values 5.4 8.2 3.8
[19]
SNU475 NFATC2
Mean 0.671
Standard deviation 0.23
Values 0.51 0.83
[20]
THLE NFATC2
Mean 1.46
Standard deviation 0.081
Values 1.4 1.5
[21]
liver NFATC2
Mean 4.46
Standard deviation 1.2
Values 5.9 3.9 3.3 4.7
[22]
ref_hepatocyte IFNG
Mean 0.182
Standard deviation 0.29
Values 0 0 0 0.23 0.67
[23]
HepG2 IFNG
Mean 0
Standard deviation 0
Values 0 0
[24]
HepG2.C3A IFNG
Mean 0
Standard deviation 0
Values 0 0
[25]
HuH.7 IFNG
Mean 0
Standard deviation 0
Values 0 0 0
[26]
SNU475 IFNG
Mean 0.206
Standard deviation 0.22
Values 0.36 0.051
[27]
THLE IFNG
Mean 0
Standard deviation 0
Values 0 0
[28]
liver IFNG
Mean 0.0524
Standard deviation 0.037
Values 0.024 0.057 0.1 0.026
[29]
ref_hepatocyte FOXP3
Mean 0.132
Standard deviation 0.21
Values 0 0 0 0.48 0.18
[30]
HepG2 FOXP3
Mean 0.0315
Standard deviation 0.02
Values 0.046 0.017
[31]
HepG2.C3A FOXP3
Mean 0.0302
Standard deviation 0.012
Values 0.039 0.021
[32]
HuH.7 FOXP3
Mean 0.00975
Standard deviation 0.0086
Values 0.016 0.013 0
[33]
SNU475 FOXP3
Mean 0.049
Standard deviation 0.017
Values 0.037 0.061
[34]
THLE FOXP3
Mean 0.0192
Standard deviation 0.01
Values 0.012 0.027
[35]
liver FOXP3
Mean 0.22
Standard deviation 0.32
Values 0.71 0.057 0.051 0.066
[36]
ref_hepatocyte IL2RA
Mean 0.131
Standard deviation 0.1
Values 0.15 0.26 0.19 0 0.057
[37]
HepG2 IL2RA
Mean 0
Standard deviation 0
Values 0 0
[38]
HepG2.C3A IL2RA
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[39]
HuH.7 IL2RA
Mean 0
Standard deviation 0
Values 0 0 0
[40]
SNU475 IL2RA
Mean 0.00992
Standard deviation 0.0075
Values 0.0046 0.015
[41]
THLE IL2RA
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[42]
liver IL2RA
Mean 0.27
Standard deviation 0.33
Values 0.024 0.2 0.1 0.75
[43]
ref_hepatocyte CR1
Mean 0.122
Standard deviation 0.2
Values 0 0 0 0.16 0.45
[44]
HepG2 CR1
Mean 0.0458
Standard deviation 0.016
Values 0.057 0.034
[45]
HepG2.C3A CR1
Mean 0.0598
Standard deviation 0.039
Values 0.087 0.032
[46]
HuH.7 CR1
Mean 0.0744
Standard deviation 0.041
Values 0.033 0.12 0.075
[47]
SNU475 CR1
Mean 0.0517
Standard deviation 0.027
Values 0.032 0.071
[48]
THLE CR1
Mean 0.039
Standard deviation 0.005
Values 0.035 0.043
[49]
liver CR1
Mean 5.72
Standard deviation 4.3
Values 1.5 11 2.9 7.9
[50]
ref_hepatocyte TNFRSF18
Mean 0.0163
Standard deviation 0.036
Values 0 0 0 0 0.081
[51]
HepG2 TNFRSF18
Mean 0.0472
Standard deviation 0.0061
Values 0.052 0.043
[52]
HepG2.C3A TNFRSF18
Mean 0.0263
Standard deviation 0.023
Values 0.0097 0.043
[53]
HuH.7 TNFRSF18
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[54]
SNU475 TNFRSF18
Mean 0.0241
Standard deviation 0.0053
Values 0.028 0.02
[55]
THLE TNFRSF18
Mean 0
Standard deviation 0
Values 0 0
[56]
liver TNFRSF18
Mean 0.0276
Standard deviation 0.03
Values 0.071 0.014 0.026 0
[57]
ref_hepatocyte IL2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[58]
HepG2 IL2
Mean 0
Standard deviation 0
Values 0 0
[59]
HepG2.C3A IL2
Mean 0
Standard deviation 0
Values 0 0
[60]
HuH.7 IL2
Mean 0
Standard deviation 0
Values 0 0 0
[61]
SNU475 IL2
Mean 0.00464
Standard deviation 0.0066
Values 0.0093 0
[62]
THLE IL2
Mean 0
Standard deviation 0
Values 0 0
[63]
liver IL2
Mean 0.00918
Standard deviation 0.011
Values 0.024 0 0 0.013
[64]
ref_hepatocyte CTLA4
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[65]
HepG2 CTLA4
Mean 0.00788
Standard deviation 0.0051
Values 0.011 0.0043
[66]
HepG2.C3A CTLA4
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[67]
HuH.7 CTLA4
Mean 0.00487
Standard deviation 0.0043
Values 0.0082 0.0064 0
[68]
SNU475 CTLA4
Mean 0
Standard deviation 0
Values 0 0
[69]
THLE CTLA4
Mean 0.0361
Standard deviation 0.0092
Values 0.03 0.043
[70]
liver CTLA4
Mean 0.0171
Standard deviation 0.02
Values 0 0.029 0 0.04