REACTOME_RSK_ACTIVATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 MAPK1 Mitogen-activated protein kinase 1 [1] 0.74[2] 0.40[3] 0.73[4] 1.21[5] 1.01[6] 1.01[7]
2 RPS6KA3 Ribosomal protein S6 kinase alpha-3 [8] [9] [10] [11] [12] [13] [14]
3 RPS6KA1 Ribosomal protein S6 kinase alpha-1 [15] [16] [17] [18] [19] [20] [21]
4 MAPK3 Mitogen-activated protein kinase 3 [22] 0.88[23] 0.44[24] 0.99[25] -0.21[26] -0.04[27] -1.80[28]
5 PDPK1 3-phosphoinositide-dependent protein kinase 1 [29] 1.36[30] 2.07[31] 1.29[32] 0.80[33] 1.34[34] 1.74[35]
6 RPS6KA2 Ribosomal protein S6 kinase alpha-2 [36] [37] [38] [39] [40] [41] [42]
7 RPS6KA6 Ribosomal protein S6 kinase alpha-6 [43] [44] [45] [46] [47] [48] [49]
[1]
ref_hepatocyte MAPK1
Mean 10.7
Standard deviation 3.7
Values 14 13 13 6.1 7.4
[2]
HepG2 MAPK1
Mean 77.6
Standard deviation 22
Values 62 93
[3]
HepG2.C3A MAPK1
Mean 76.1
Standard deviation 7.2
Values 71 81
[4]
HuH.7 MAPK1
Mean 64.8
Standard deviation 7.4
Values 73 60 61
[5]
SNU475 MAPK1
Mean 71.1
Standard deviation 8
Values 77 65
[6]
THLE MAPK1
Mean 62.4
Standard deviation 14
Values 53 72
[7]
liver MAPK1
Mean 52.3
Standard deviation 14
Values 39 68 41 61
[8]
ref_hepatocyte RPS6KA3
Mean 9.94
Standard deviation 10
Values 28 6.9 4.8 4.1 6.3
[9]
HepG2 RPS6KA3
Missing
[10]
HepG2.C3A RPS6KA3
Missing
[11]
HuH.7 RPS6KA3
Missing
[12]
SNU475 RPS6KA3
Missing
[13]
THLE RPS6KA3
Missing
[14]
liver RPS6KA3
Missing
[15]
ref_hepatocyte RPS6KA1
Mean 4.78
Standard deviation 3.4
Values 10 5.6 3.5 2.9 1.5
[16]
HepG2 RPS6KA1
Missing
[17]
HepG2.C3A RPS6KA1
Missing
[18]
HuH.7 RPS6KA1
Missing
[19]
SNU475 RPS6KA1
Missing
[20]
THLE RPS6KA1
Missing
[21]
liver RPS6KA1
Missing
[22]
ref_hepatocyte MAPK3
Mean 4.16
Standard deviation 1.3
Values 5.1 2.8 3.6 6 3.3
[23]
HepG2 MAPK3
Mean 33.1
Standard deviation 5.2
Values 37 29
[24]
HepG2.C3A MAPK3
Mean 30.4
Standard deviation 12
Values 39 22
[25]
HuH.7 MAPK3
Mean 30
Standard deviation 4.8
Values 34 25 32
[26]
SNU475 MAPK3
Mean 10.2
Standard deviation 2.4
Values 12 8.5
[27]
THLE MAPK3
Mean 11.6
Standard deviation 1.1
Values 11 12
[28]
liver MAPK3
Mean 2.87
Standard deviation 2.4
Values 5 0.81 4.8 0.82
[29]
ref_hepatocyte PDPK1
Mean 3.54
Standard deviation 2
Values 6.9 3.4 3.6 1.8 2
[30]
HepG2 PDPK1
Mean 39.4
Standard deviation 5.6
Values 35 43
[31]
HepG2.C3A PDPK1
Mean 80.1
Standard deviation 13
Values 89 71
[32]
HuH.7 PDPK1
Mean 31.4
Standard deviation 4.5
Values 35 33 26
[33]
SNU475 PDPK1
Mean 17.6
Standard deviation 0.21
Values 17 18
[34]
THLE PDPK1
Mean 25.9
Standard deviation 4.6
Values 23 29
[35]
liver PDPK1
Mean 28.5
Standard deviation 5.1
Values 34 27 22 31
[36]
ref_hepatocyte RPS6KA2
Mean 1.31
Standard deviation 0.89
Values 0 1.8 2.4 1.1 1.3
[37]
HepG2 RPS6KA2
Missing
[38]
HepG2.C3A RPS6KA2
Missing
[39]
HuH.7 RPS6KA2
Missing
[40]
SNU475 RPS6KA2
Missing
[41]
THLE RPS6KA2
Missing
[42]
liver RPS6KA2
Missing
[43]
ref_hepatocyte RPS6KA6
Mean 0.219
Standard deviation 0.15
Values 0.11 0.36 0.4 0.043 0.18
[44]
HepG2 RPS6KA6
Missing
[45]
HepG2.C3A RPS6KA6
Missing
[46]
HuH.7 RPS6KA6
Missing
[47]
SNU475 RPS6KA6
Missing
[48]
THLE RPS6KA6
Missing
[49]
liver RPS6KA6
Missing