REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN_1_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 PITPNA Phosphatidylinositol transfer protein alpha isoform [1] -1.39[2] -1.44[3] -0.72[4] -0.84[5] -0.43[6] -0.63[7]
2 PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1.33[8] 1.21[9] 0.71[10] 0.82[11] 0.59[12] -0.33[13]
3 NTN1 Netrin-1 [14] -4.32[15] -4.74[16] -1.00[17] -6.65[18] -4.09[19] 2.61[20]
4 TRPC1 Short transient receptor potential channel 1 [21] -0.08[22] 1.50[23] 1.84[24] 1.05[25] 1.34[26] -0.73[27]
5 TRPC5 Short transient receptor potential channel 5 [28] [29] [30] [31] -5.40[32] -7.13[33] 3.85[34]
6 TRPC6 Short transient receptor potential channel 6 [35] -3.07[36] -1.24[37] -0.37[38] -1.14[39] -2.57[40] 2.61[41]
7 TRPC4 Short transient receptor potential channel 4 [42] [43] [44] [45] [46] [47] [48]
8 TRPC7 Short transient receptor potential channel 7 [49] [50] [51] [52] [53] [54] [55]
9 DCC Netrin receptor DCC [56] [57] [58] [59] [60] [61] [62]
10 TRPC3 Short transient receptor potential channel 3 [63] [64] [65] [66] [67] [68] [69]
[1]
ref_hepatocyte PITPNA
Mean 7.7
Standard deviation 3.8
Values 3.7 5.5 13 10 6.1
[2]
HepG2 PITPNA
Mean 28.9
Standard deviation 3.1
Values 31 27
[3]
HepG2.C3A PITPNA
Mean 20.8
Standard deviation 1
Values 22 20
[4]
HuH.7 PITPNA
Mean 29.3
Standard deviation 6.3
Values 31 22 34
[5]
SNU475 PITPNA
Mean 31.5
Standard deviation 3.4
Values 34 29
[6]
THLE PITPNA
Mean 38.9
Standard deviation 5.4
Values 35 43
[7]
liver PITPNA
Mean 11.2
Standard deviation 1.5
Values 13 11 12 9.3
[8]
ref_hepatocyte PLCG1
Mean 3.54
Standard deviation 4.5
Values 11 2.4 1.7 0.91 1.2
[9]
HepG2 PLCG1
Mean 87.8
Standard deviation 4.3
Values 91 85
[10]
HepG2.C3A PLCG1
Mean 60.1
Standard deviation 10
Values 67 53
[11]
HuH.7 PLCG1
Mean 36.2
Standard deviation 5.9
Values 40 30 39
[12]
SNU475 PLCG1
Mean 45.9
Standard deviation 1.9
Values 47 45
[13]
THLE PLCG1
Mean 36.2
Standard deviation 0.92
Values 36 37
[14]
liver PLCG1
Mean 6.36
Standard deviation 4.9
Values 2.3 8.9 2.2 12
[15]
ref_hepatocyte NTN1
Mean 0.538
Standard deviation 0.57
Values 0 0.22 0.55 1.5 0.45
[16]
HepG2 NTN1
Mean 0.266
Standard deviation 0.22
Values 0.42 0.11
[17]
HepG2.C3A NTN1
Mean 0.147
Standard deviation 0.011
Values 0.16 0.14
[18]
HuH.7 NTN1
Mean 1.68
Standard deviation 0.15
Values 1.6 1.9 1.6
[19]
SNU475 NTN1
Mean 0.0393
Standard deviation 0.016
Values 0.028 0.051
[20]
THLE NTN1
Mean 0.215
Standard deviation 0.056
Values 0.25 0.18
[21]
liver NTN1
Mean 7.41
Standard deviation 5
Values 3.7 13 2.8 9.9
[22]
ref_hepatocyte TRPC1
Mean 0.42
Standard deviation 0.89
Values 2 0.088 0 0 0
[23]
HepG2 TRPC1
Mean 3.91
Standard deviation 0.98
Values 3.2 4.6
[24]
HepG2.C3A TRPC1
Mean 8.7
Standard deviation 1.4
Values 9.7 7.7
[25]
HuH.7 TRPC1
Mean 9.44
Standard deviation 3.8
Values 7.3 14 7.2
[26]
SNU475 TRPC1
Mean 6.37
Standard deviation 2
Values 7.8 4.9
[27]
THLE TRPC1
Mean 7.24
Standard deviation 1.2
Values 8.1 6.4
[28]
liver TRPC1
Mean 0.573
Standard deviation 0.33
Values 0.38 0.5 0.36 1.1
[29]
ref_hepatocyte TRPC5
Mean 0.0546
Standard deviation 0.059
Values 0 0.14 0 0.052 0.081
[30]
HepG2 TRPC5
Mean 0
Standard deviation 0
Values 0 0
[31]
HepG2.C3A TRPC5
Mean 0
Standard deviation 0
Values 0 0
[32]
HuH.7 TRPC5
Mean 0
Standard deviation 0
Values 0 0 0
[33]
SNU475 TRPC5
Mean 0.00949
Standard deviation 0.0063
Values 0.014 0.0051
[34]
THLE TRPC5
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[35]
liver TRPC5
Mean 1.77
Standard deviation 1
Values 1.4 2 0.64 3.1
[36]
ref_hepatocyte TRPC6
Mean 0.00488
Standard deviation 0.011
Values 0 0 0 0 0.024
[37]
HepG2 TRPC6
Mean 0.00573
Standard deviation 0.0081
Values 0.011 0
[38]
HepG2.C3A TRPC6
Mean 0.0151
Standard deviation 0.0062
Values 0.019 0.011
[39]
HuH.7 TRPC6
Mean 0.0236
Standard deviation 0.008
Values 0.033 0.019 0.019
[40]
SNU475 TRPC6
Mean 0.0162
Standard deviation 0.023
Values 0.032 0
[41]
THLE TRPC6
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[42]
liver TRPC6
Mean 0.0673
Standard deviation 0.076
Values 0 0.071 0.026 0.17
[43]
ref_hepatocyte TRPC4
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[44]
HepG2 TRPC4
Mean 0
Standard deviation 0
Values 0 0
[45]
HepG2.C3A TRPC4
Mean 0
Standard deviation 0
Values 0 0
[46]
HuH.7 TRPC4
Mean 0.00701
Standard deviation 0.0065
Values 0.0082 0.013 0
[47]
SNU475 TRPC4
Mean 5.92
Standard deviation 1.2
Values 6.8 5.1
[48]
THLE TRPC4
Mean 0.432
Standard deviation 0.21
Values 0.28 0.58
[49]
liver TRPC4
Mean 0.0943
Standard deviation 0.025
Values 0.071 0.086 0.13 0.093
[50]
ref_hepatocyte TRPC7
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[51]
HepG2 TRPC7
Missing
[52]
HepG2.C3A TRPC7
Missing
[53]
HuH.7 TRPC7
Missing
[54]
SNU475 TRPC7
Missing
[55]
THLE TRPC7
Missing
[56]
liver TRPC7
Missing
[57]
ref_hepatocyte DCC
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[58]
HepG2 DCC
Mean 0
Standard deviation 0
Values 0 0
[59]
HepG2.C3A DCC
Mean 0
Standard deviation 0
Values 0 0
[60]
HuH.7 DCC
Mean 0
Standard deviation 0
Values 0 0 0
[61]
SNU475 DCC
Mean 0.0228
Standard deviation 0.032
Values 0 0.046
[62]
THLE DCC
Mean 0
Standard deviation 0
Values 0 0
[63]
liver DCC
Mean 0.0171
Standard deviation 0.02
Values 0 0.029 0 0.04
[64]
ref_hepatocyte TRPC3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[65]
HepG2 TRPC3
Mean 0
Standard deviation 0
Values 0 0
[66]
HepG2.C3A TRPC3
Mean 0
Standard deviation 0
Values 0 0
[67]
HuH.7 TRPC3
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[68]
SNU475 TRPC3
Mean 0.0948
Standard deviation 0.088
Values 0.032 0.16
[69]
THLE TRPC3
Mean 0.612
Standard deviation 0.03
Values 0.63 0.59
[70]
liver TRPC3
Mean 0.107
Standard deviation 0.081
Values 0.071 0.23 0.051 0.079