REACTOME_RIPK1_MEDIATED_REGULATED_NECROSIS | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | UBB | Polyubiquitin-B | [1] | -0.75[2] | -1.28[3] | -0.99[4] | -1.44[5] | -0.96[6] | -0.40[7] |
2 | RPS27A | Ubiquitin-40S ribosomal protein S27a | [8] | [9] | [10] | [11] | [12] | [13] | [14] |
3 | UBC | Polyubiquitin-C | [15] | -0.30[16] | -0.53[17] | -0.63[18] | -0.59[19] | -0.59[20] | 0.06[21] |
4 | HSP90AA1 | Heat shock protein HSP 90-alpha | [22] | 0.81[23] | 1.45[24] | 0.81[25] | 1.43[26] | 1.13[27] | 0.23[28] |
5 | CDC37 | Hsp90 co-chaperone Cdc37 | [29] | 0.69[30] | -0.29[31] | 0.22[32] | -0.47[33] | 0.13[34] | -0.50[35] |
6 | UBA52 | Ubiquitin-60S ribosomal protein L40 | [36] | 2.13[37] | 1.71[38] | 2.89[39] | 0.81[40] | 1.64[41] | 0.82[42] |
7 | FLOT1 | Flotillin-1 | [43] | 0.83[44] | 1.01[45] | 0.51[46] | 1.54[47] | 0.72[48] | 0.23[49] |
8 | STUB1 | E3 ubiquitin-protein ligase CHIP | [50] | -0.53[51] | -0.84[52] | -1.36[53] | -1.33[54] | -0.98[55] | -0.77[56] |
9 | SDCBP | Syntenin-1 | [57] | 0.44[58] | -0.21[59] | -0.71[60] | 2.37[61] | 2.01[62] | 1.46[63] |
10 | FLOT2 | Flotillin-2 | [64] | 0.93[65] | 0.53[66] | 1.05[67] | 0.98[68] | 0.70[69] | 2.03[70] |
11 | TNFSF10 | Tumor necrosis factor ligand superfamily member 10 | [71] | -3.02[72] | -1.75[73] | 1.01[74] | -1.14[75] | -4.36[76] | 0.09[77] |
12 | CFLAR | CASP8 and FADD-like apoptosis regulator | [78] | 1.07[79] | 1.48[80] | 1.17[81] | 0.79[82] | 0.97[83] | 3.04[84] |
13 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | [85] | -1.66[86] | -0.97[87] | -3.23[88] | -1.78[89] | 2.00[90] | -0.60[91] |
14 | TNFRSF10 | Tumor necrosis factor receptor superfamily member 10B | [92] | 3.44[93] | 2.98[94] | 2.92[95] | 1.00[96] | 2.64[97] | 1.52[98] |
15 | PDCD6IP | Programmed cell death 6-interacting protein | [99] | 1.97[100] | 1.63[101] | 3.03[102] | 2.22[103] | 2.66[104] | 2.56[105] |
16 | FAS | Tumor necrosis factor receptor superfamily member 6 | [106] | -0.15[107] | 0.30[108] | -7.57[109] | -0.41[110] | 0.13[111] | -0.24[112] |
17 | BIRC2 | Baculoviral IAP repeat-containing protein 2 | [113] | 1.69[114] | 2.32[115] | 1.41[116] | 1.75[117] | 2.56[118] | 2.21[119] |
18 | FADD | FAS-associated death domain protein | [120] | 1.49[121] | 0.45[122] | 1.31[123] | 3.27[124] | 1.10[125] | -0.29[126] |
19 | CASP8 | Caspase-8 | [127] | 1.47[128] | 1.71[129] | 1.02[130] | 1.25[131] | 0.53[132] | 0.06[133] |
20 | TNFRSF10 | Tumor necrosis factor receptor superfamily member 10A | [134] | 0.01[135] | -0.78[136] | -0.63[137] | -1.69[138] | -1.92[139] | -0.23[140] |
21 | OGT | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subu | 2.67[141] | 3.20[142] | 3.37[143] | 2.86[144] | 2.85[145] | 3.83[146] | |
22 | TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein | 1.19[147] | 0.70[148] | -0.33[149] | 0.35[150] | 0.22[151] | 0.89[152] | |
23 | TRAF2 | TNF receptor-associated factor 2 | [153] | 1.68[154] | 1.41[155] | 1.28[156] | 1.46[157] | 1.49[158] | 0.68[159] |
24 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | [160] | 1.74[161] | 1.57[162] | 1.39[163] | 2.41[164] | 1.96[165] | 2.96[166] |
25 | XIAP | E3 ubiquitin-protein ligase XIAP | [167] | 2.97[168] | 3.23[169] | 3.82[170] | 3.93[171] | 3.37[172] | 4.16[173] |
26 | PELI1 | E3 ubiquitin-protein ligase pellino homolog 1 | [174] | 1.60[175] | 2.18[176] | 2.83[177] | 1.08[178] | 1.19[179] | 2.88[180] |
27 | MLKL | Mixed lineage kinase domain-like protein | [181] | 1.29[182] | 0.85[183] | -0.68[184] | 0.82[185] | 1.23[186] | 1.26[187] |
28 | RIPK3 | Receptor-interacting serine/threonine-protein kinase 3 | [188] | -5.19[189] | [190] | -4.07[191] | [192] | -4.02[193] | 2.03[194] |
29 | FASLG | Tumor necrosis factor ligand superfamily member 6 | [195] | -2.36[196] | -0.82[197] | -4.65[198] | [199] | [200] | 2.07[201] |