REACTOME_RHO_GTPASES_ACTIVATE_CIT Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 MYL6 Myosin light polypeptide 6 [1] -1.86[2] -1.35[3] -2.33[4] -1.42[5] -1.47[6] -1.87[7]
2 MYL12B Myosin regulatory light chain 12B [8] -0.60[9] -0.15[10] 0.00[11] -0.49[12] -0.89[13] -0.64[14]
3 RHOA Transforming protein RhoA [15] 0.47[16] 0.31[17] 0.70[18] -0.20[19] 0.56[20] 0.43[21]
4 RHOC Rho-related GTP-binding protein RhoC [22] -0.16[23] -0.23[24] -0.48[25] 0.02[26] 0.19[27] -0.94[28]
5 RHOB Rho-related GTP-binding protein RhoB [29] 0.62[30] 0.38[31] -1.58[32] -1.27[33] -1.82[34] 1.63[35]
6 MYH9 Myosin-9 [36] 2.83[37] 1.61[38] 1.75[39] 2.25[40] 2.43[41] 2.14[42]
7 RAC1 Ras-related C3 botulinum toxin substrate 1 [43] 1.02[44] 1.02[45] 1.91[46] 1.04[47] 1.32[48] 0.78[49]
8 PPP1CB Serine/threonine-protein phosphatase PP1-beta catalytic subunit [50] 1.17[51] 2.07[52] 2.34[53] 1.79[54] 1.91[55] 2.25[56]
9 CDKN1B Cyclin-dependent kinase inhibitor 1B [57] 1.33[58] 2.10[59] 2.47[60] -0.08[61] 0.68[62] 0.84[63]
10 MYH14 Myosin-14 [64] 2.29[65] 2.74[66] 2.89[67] 1.52[68] -1.61[69] 3.00[70]
11 MYH10 Myosin-10 [71] 3.74[72] 4.09[73] 4.83[74] 3.50[75] 3.68[76] 3.81[77]
12 MYL9 Myosin regulatory light polypeptide 9 [78] 2.47[79] 2.61[80] 0.10[81] 5.61[82] 3.36[83] 1.67[84]
13 PPP1R12A Protein phosphatase 1 regulatory subunit 12A [85] 1.57[86] 3.63[87] 3.53[88] 3.76[89] 2.98[90] 3.50[91]
14 PRC1 Protein regulator of cytokinesis 1 [92] 3.50[93] 3.94[94] 4.57[95] 3.50[96] 4.80[97] 0.56[98]
15 PPP1R12B Protein phosphatase 1 regulatory subunit 12B [99] 3.50[100] 4.68[101] 5.26[102] 5.04[103] 4.23[104] 6.33[105]
16 KIF14 Kinesin-like protein KIF14 [106] 3.00[107] 5.56[108] 5.95[109] 5.76[110] 6.16[111] 2.44[112]
17 DLG4 Disks large homolog 4 [113] 4.19[114] 4.81[115] 3.74[116] 2.99[117] 5.50[118] 3.45[119]
18 CIT Citron Rho-interacting kinase [120] 5.67[121] 6.48[122] 7.59[123] 6.32[124] 7.25[125] 3.80[126]
19 MYH11 Myosin-11 [127] 4.78[128] 4.74[129] 5.20[130] 4.70[131] 4.14[132] 11.71[133]
[1]
ref_hepatocyte MYL6
Mean 1.19e+03
Standard deviation 1.2e+03
Values 9.4e+02 3.2e+03 7.6e+02 5.1e+02 5.1e+02
[2]
HepG2 MYL6
Mean 272
Standard deviation 59
Values 2.3e+02 3.1e+02
[3]
HepG2.C3A MYL6
Mean 275
Standard deviation 92
Values 2.1e+02 3.4e+02
[4]
HuH.7 MYL6
Mean 118
Standard deviation 30
Values 1.1e+02 94 1.5e+02
[5]
SNU475 MYL6
Mean 403
Standard deviation 1.9e+02
Values 5.4e+02 2.7e+02
[6]
THLE MYL6
Mean 354
Standard deviation 52
Values 3.2e+02 3.9e+02
[7]
liver MYL6
Mean 138
Standard deviation 1.3e+02
Values 2.6e+02 37 2.3e+02 21
[8]
ref_hepatocyte MYL12B
Mean 317
Standard deviation 2e+02
Values 2e+02 6.8e+02 2.5e+02 2.4e+02 2.1e+02
[9]
HepG2 MYL12B
Mean 174
Standard deviation 36
Values 1.5e+02 2e+02
[10]
HepG2.C3A MYL12B
Mean 168
Standard deviation 40
Values 1.4e+02 2e+02
[11]
HuH.7 MYL12B
Mean 158
Standard deviation 19
Values 1.5e+02 1.4e+02 1.8e+02
[12]
SNU475 MYL12B
Mean 204
Standard deviation 67
Values 2.5e+02 1.6e+02
[13]
THLE MYL12B
Mean 140
Standard deviation 22
Values 1.2e+02 1.6e+02
[14]
liver MYL12B
Mean 85.6
Standard deviation 68
Values 1.5e+02 34 1.4e+02 20
[15]
ref_hepatocyte RHOA
Mean 177
Standard deviation 1.2e+02
Values 2.2e+02 3.8e+02 1.4e+02 75 79
[16]
HepG2 RHOA
Mean 204
Standard deviation 38
Values 2.3e+02 1.8e+02
[17]
HepG2.C3A RHOA
Mean 129
Standard deviation 1.6
Values 1.3e+02 1.3e+02
[18]
HuH.7 RHOA
Mean 144
Standard deviation 23
Values 1.6e+02 1.2e+02 1.6e+02
[19]
SNU475 RHOA
Mean 139
Standard deviation 21
Values 1.5e+02 1.2e+02
[20]
THLE RHOA
Mean 214
Standard deviation 38
Values 1.9e+02 2.4e+02
[21]
liver RHOA
Mean 101
Standard deviation 59
Values 1.6e+02 54 1.4e+02 46
[22]
ref_hepatocyte RHOC
Mean 128
Standard deviation 1.2e+02
Values 28 2.1e+02 3.1e+02 56 39
[23]
HepG2 RHOC
Mean 95.1
Standard deviation 9.4
Values 1e+02 88
[24]
HepG2.C3A RHOC
Mean 64.3
Standard deviation 2.3
Values 66 63
[25]
HuH.7 RHOC
Mean 45.7
Standard deviation 7.4
Values 39 53 45
[26]
SNU475 RHOC
Mean 117
Standard deviation 12
Values 1.3e+02 1.1e+02
[27]
THLE RHOC
Mean 120
Standard deviation 7.4
Values 1.1e+02 1.3e+02
[28]
liver RHOC
Mean 28.1
Standard deviation 21
Values 52 13 38 9.2
[29]
ref_hepatocyte RHOB
Mean 121
Standard deviation 74
Values 81 64 88 2.5e+02 1.3e+02
[30]
HepG2 RHOB
Mean 154
Standard deviation 31
Values 1.8e+02 1.3e+02
[31]
HepG2.C3A RHOB
Mean 92.7
Standard deviation 27
Values 1.1e+02 74
[32]
HuH.7 RHOB
Mean 20.2
Standard deviation 3.4
Values 17 24 20
[33]
SNU475 RHOB
Mean 45.5
Standard deviation 23
Values 61 30
[34]
THLE RHOB
Mean 28.2
Standard deviation 1.3
Values 27 29
[35]
liver RHOB
Mean 158
Standard deviation 87
Values 1.3e+02 1.5e+02 71 2.8e+02
[36]
ref_hepatocyte MYH9
Mean 89.9
Standard deviation 85
Values 42 2e+02 1.7e+02 21 22
[37]
HepG2 MYH9
Mean 531
Standard deviation 80
Values 5.9e+02 4.7e+02
[38]
HepG2.C3A MYH9
Mean 161
Standard deviation 42
Values 1.9e+02 1.3e+02
[39]
HuH.7 MYH9
Mean 151
Standard deviation 45
Values 2e+02 1.3e+02 1.2e+02
[40]
SNU475 MYH9
Mean 384
Standard deviation 1.4e+02
Values 4.8e+02 2.9e+02
[41]
THLE MYH9
Mean 399
Standard deviation 1.2e+02
Values 3.1e+02 4.9e+02
[42]
liver MYH9
Mean 167
Standard deviation 46
Values 1.1e+02 2e+02 1.5e+02 2.1e+02
[43]
ref_hepatocyte RAC1
Mean 52
Standard deviation 20
Values 28 59 81 45 47
[44]
HepG2 RAC1
Mean 87.4
Standard deviation 1.9
Values 89 86
[45]
HepG2.C3A RAC1
Mean 62
Standard deviation 7.4
Values 67 57
[46]
HuH.7 RAC1
Mean 97.2
Standard deviation 9.7
Values 1e+02 86 1e+02
[47]
SNU475 RAC1
Mean 96.5
Standard deviation 10
Values 89 1e+02
[48]
THLE RAC1
Mean 107
Standard deviation 19
Values 94 1.2e+02
[49]
liver RAC1
Mean 37.8
Standard deviation 32
Values 63 12 67 9.5
[50]
ref_hepatocyte PPP1CB
Mean 31.9
Standard deviation 30
Values 65 64 8.8 6.2 16
[51]
HepG2 PPP1CB
Mean 59.8
Standard deviation 14
Values 50 70
[52]
HepG2.C3A PPP1CB
Mean 78.8
Standard deviation 12
Values 71 87
[53]
HuH.7 PPP1CB
Mean 80.4
Standard deviation 9.9
Values 92 76 74
[54]
SNU475 PPP1CB
Mean 99.4
Standard deviation 25
Values 1.2e+02 82
[55]
THLE PPP1CB
Mean 98.3
Standard deviation 1.6
Values 99 97
[56]
liver PPP1CB
Mean 64.1
Standard deviation 7.2
Values 67 68 67 53
[57]
ref_hepatocyte CDKN1B
Mean 13.8
Standard deviation 6
Values 23 13 7.5 10 15
[58]
HepG2 CDKN1B
Mean 28.7
Standard deviation 3.4
Values 31 26
[59]
HepG2.C3A CDKN1B
Mean 34.7
Standard deviation 1.4
Values 34 36
[60]
HuH.7 CDKN1B
Mean 38.2
Standard deviation 3.7
Values 35 42 37
[61]
SNU475 CDKN1B
Mean 11.8
Standard deviation 2.9
Values 14 9.7
[62]
THLE CDKN1B
Mean 18.2
Standard deviation 3.4
Values 16 21
[63]
liver CDKN1B
Mean 10.5
Standard deviation 3.5
Values 9.9 14 5.8 12
[64]
ref_hepatocyte MYH14
Mean 5.98
Standard deviation 2.3
Values 4.5 5.3 3.5 9.3 7.3
[65]
HepG2 MYH14
Mean 24.3
Standard deviation 8.5
Values 30 18
[66]
HepG2.C3A MYH14
Mean 23.4
Standard deviation 7
Values 28 18
[67]
HuH.7 MYH14
Mean 22.1
Standard deviation 4.6
Values 26 23 17
[68]
SNU475 MYH14
Mean 15.5
Standard deviation 1.9
Values 17 14
[69]
THLE MYH14
Mean 1.6
Standard deviation 1.1
Values 2.4 0.85
[70]
liver MYH14
Mean 20.2
Standard deviation 6.7
Values 20 21 12 28
[71]
ref_hepatocyte MYH10
Mean 5.81
Standard deviation 6.6
Values 17 5.7 1.9 1.6 2.5
[72]
HepG2 MYH10
Mean 64.6
Standard deviation 17
Values 53 76
[73]
HepG2.C3A MYH10
Mean 58.3
Standard deviation 5
Values 55 62
[74]
HuH.7 MYH10
Mean 82.4
Standard deviation 29
Values 1.1e+02 57 76
[75]
SNU475 MYH10
Mean 59.2
Standard deviation 10
Values 66 52
[76]
THLE MYH10
Mean 61.3
Standard deviation 12
Values 53 70
[77]
liver MYH10
Mean 34.4
Standard deviation 12
Values 23 47 25 43
[78]
ref_hepatocyte MYL9
Mean 5.03
Standard deviation 4.9
Values 5.1 13 5.9 0.6 0.89
[79]
HepG2 MYL9
Mean 23.1
Standard deviation 1.3
Values 22 24
[80]
HepG2.C3A MYL9
Mean 18
Standard deviation 3.8
Values 15 21
[81]
HuH.7 MYL9
Mean 2.69
Standard deviation 0.26
Values 2.9 2.4 2.7
[82]
SNU475 MYL9
Mean 222
Standard deviation 1.5e+02
Values 3.3e+02 1.2e+02
[83]
THLE MYL9
Mean 42.5
Standard deviation 9.6
Values 36 49
[84]
liver MYL9
Mean 6.76
Standard deviation 7.5
Values 5.5 1.6 18 2.2
[85]
ref_hepatocyte PPP1R12A
Mean 4
Standard deviation 2.4
Values 6.7 6 4 1.4 1.8
[86]
HepG2 PPP1R12A
Mean 9.87
Standard deviation 3.8
Values 7.2 13
[87]
HepG2.C3A PPP1R12A
Mean 29.1
Standard deviation 5.2
Values 25 33
[88]
HuH.7 PPP1R12A
Mean 23.1
Standard deviation 3.3
Values 22 27 20
[89]
SNU475 PPP1R12A
Mean 48.8
Standard deviation 7.9
Values 54 43
[90]
THLE PPP1R12A
Mean 25.8
Standard deviation 4.4
Values 29 23
[91]
liver PPP1R12A
Mean 19.1
Standard deviation 2.7
Values 18 23 17 19
[92]
ref_hepatocyte PRC1
Mean 3.84
Standard deviation 4.6
Values 4.9 11 1.1 1.1 0.5
[93]
HepG2 PRC1
Mean 36
Standard deviation 5.3
Values 32 40
[94]
HepG2.C3A PRC1
Mean 34.6
Standard deviation 16
Values 23 46
[95]
HuH.7 PRC1
Mean 45.3
Standard deviation 16
Values 53 26 57
[96]
SNU475 PRC1
Mean 39.3
Standard deviation 5
Values 43 36
[97]
THLE PRC1
Mean 87.8
Standard deviation 19
Values 74 1e+02
[98]
liver PRC1
Mean 2.39
Standard deviation 2
Values 0.82 4.2 4.1 0.46
[99]
ref_hepatocyte PPP1R12B
Mean 0.528
Standard deviation 0.18
Values 0.4 0.82 0.5 0.55 0.37
[100]
HepG2 PPP1R12B
Mean 4.96
Standard deviation 2.1
Values 3.5 6.4
[101]
HepG2.C3A PPP1R12B
Mean 7.94
Standard deviation 1.3
Values 8.8 7
[102]
HuH.7 PPP1R12B
Mean 10.1
Standard deviation 2.3
Values 11 12 7.4
[103]
SNU475 PPP1R12B
Mean 15.7
Standard deviation 8.1
Values 21 10
[104]
THLE PPP1R12B
Mean 8.14
Standard deviation 0.7
Values 7.6 8.6
[105]
liver PPP1R12B
Mean 18
Standard deviation 8.2
Values 11 23 11 27
[106]
ref_hepatocyte KIF14
Mean 0.386
Standard deviation 0.42
Values 0.77 0.91 0.095 0 0.15
[107]
HepG2 KIF14
Mean 2.57
Standard deviation 1.1
Values 1.8 3.3
[108]
HepG2.C3A KIF14
Mean 10.7
Standard deviation 6.2
Values 6.3 15
[109]
HuH.7 KIF14
Mean 11.9
Standard deviation 5.7
Values 17 6 12
[110]
SNU475 KIF14
Mean 18.9
Standard deviation 3.2
Values 17 21
[111]
THLE KIF14
Mean 22.6
Standard deviation 4.7
Values 26 19
[112]
liver KIF14
Mean 0.882
Standard deviation 0.68
Values 0.42 1.7 1.2 0.24
[113]
ref_hepatocyte DLG4
Mean 0.259
Standard deviation 0.21
Values 0.17 0 0.16 0.45 0.51
[114]
HepG2 DLG4
Mean 3.93
Standard deviation 2.2
Values 5.5 2.3
[115]
HepG2.C3A DLG4
Mean 4.27
Standard deviation 0.27
Values 4.5 4.1
[116]
HuH.7 DLG4
Mean 1.73
Standard deviation 0.71
Values 1.3 2.5 1.3
[117]
SNU475 DLG4
Mean 1.85
Standard deviation 0.71
Values 1.3 2.4
[118]
THLE DLG4
Mean 9.6
Standard deviation 0.94
Values 10 8.9
[119]
liver DLG4
Mean 1.19
Standard deviation 1.3
Values 0.26 1.2 0.28 3
[120]
ref_hepatocyte CIT
Mean 0.206
Standard deviation 0.19
Values 0.54 0.16 0.065 0.15 0.11
[121]
HepG2 CIT
Mean 8.68
Standard deviation 0.59
Values 8.3 9.1
[122]
HepG2.C3A CIT
Mean 10.8
Standard deviation 3.3
Values 8.5 13
[123]
HuH.7 CIT
Mean 19.8
Standard deviation 10
Values 30 9.3 20
[124]
SNU475 CIT
Mean 14.8
Standard deviation 0.38
Values 15 15
[125]
THLE CIT
Mean 25.7
Standard deviation 4.8
Values 22 29
[126]
liver CIT
Mean 1.21
Standard deviation 0.66
Values 0.73 2 1.5 0.64
[127]
ref_hepatocyte MYH11
Mean 0.00924
Standard deviation 0.021
Values 0 0 0.046 0 0
[128]
HepG2 MYH11
Mean 0.21
Standard deviation 0.067
Values 0.26 0.16
[129]
HepG2.C3A MYH11
Mean 0.145
Standard deviation 0.068
Values 0.097 0.19
[130]
HuH.7 MYH11
Mean 0.169
Standard deviation 0.067
Values 0.15 0.12 0.24
[131]
SNU475 MYH11
Mean 0.217
Standard deviation 0.044
Values 0.19 0.25
[132]
THLE MYH11
Mean 0.133
Standard deviation 0.03
Values 0.11 0.15
[133]
liver MYH11
Mean 13
Standard deviation 16
Values 3 6.1 6.2 37