REACTOME_RHOV_GTPASE_CYCLE | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | TPM4 | Tropomyosin alpha-4 chain | [1] | -0.83[2] | -1.57[3] | -1.57[4] | -0.93[5] | -0.36[6] | -3.66[7] |
2 | CDC42 | Cell division control protein 42 homolog | [8] | -1.50[9] | -0.74[10] | -1.81[11] | -1.32[12] | -2.07[13] | -2.83[14] |
3 | TPM3 | Tropomyosin alpha-3 chain | [15] | -0.85[16] | -1.13[17] | -0.51[18] | -0.34[19] | -0.78[20] | -1.64[21] |
4 | TXNL1 | Thioredoxin-like protein 1 | [22] | -2.41[23] | -2.23[24] | -2.46[25] | -2.21[26] | -2.49[27] | -2.30[28] |
5 | CLTC | Clathrin heavy chain 1 | [29] | 0.94[30] | 1.08[31] | 1.19[32] | 0.90[33] | 1.00[34] | 1.71[35] |
6 | SPTBN1 | Spectrin beta chain, non-erythrocytic 1 | [36] | 2.08[37] | 1.66[38] | 1.99[39] | 0.63[40] | 0.94[41] | 2.21[42] |
7 | SPTAN1 | Spectrin alpha chain, non-erythrocytic 1 | [43] | 2.07[44] | 1.45[45] | 2.06[46] | 1.97[47] | 2.07[48] | 1.20[49] |
8 | NCK1 | Cytoplasmic protein NCK1 | [50] | -2.27[51] | -2.12[52] | -2.08[53] | -1.35[54] | -1.27[55] | -1.22[56] |
9 | PAK2 | Serine/threonine-protein kinase PAK 2 | [57] | 0.77[58] | 0.56[59] | 0.79[60] | -0.03[61] | 0.48[62] | 0.62[63] |
10 | MAP3K11 | Mitogen-activated protein kinase kinase kinase 11 | [64] | 0.41[65] | 0.40[66] | -0.04[67] | -0.64[68] | -0.81[69] | -0.29[70] |
11 | WASL | Neural Wiskott-Aldrich syndrome protein | [71] | -1.16[72] | -0.04[73] | 0.30[74] | 0.32[75] | -0.55[76] | 0.38[77] |
12 | WDR6 | WD repeat-containing protein 6 | [78] | 1.12[79] | 1.51[80] | 1.82[81] | 0.04[82] | 0.90[83] | 0.66[84] |
13 | EPHA2 | Ephrin type-A receptor 2 | [85] | 1.58[86] | 1.83[87] | -0.41[88] | 0.16[89] | 0.68[90] | -1.52[91] |
14 | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha | [92] | -1.15[93] | -0.98[94] | 0.04[95] | 1.28[96] | 0.75[97] | 2.25[98] |
15 | DST | Dystonin | [99] | 0.86[100] | 1.78[101] | 1.53[102] | 1.97[103] | 1.28[104] | 3.69[105] |
16 | ARHGAP1 | Rho GTPase-activating protein 12 | [106] | 0.38[107] | 1.50[108] | 1.06[109] | 0.79[110] | -0.53[111] | 0.92[112] |
17 | GIT2 | ARF GTPase-activating protein GIT2 | [113] | -0.35[114] | 0.21[115] | -0.29[116] | 0.38[117] | 0.15[118] | 0.31[119] |
18 | NCK2 | Cytoplasmic protein NCK2 | [120] | 0.12[121] | -0.25[122] | -1.90[123] | -1.11[124] | -0.40[125] | -1.57[126] |
19 | IQGAP1 | Ras GTPase-activating-like protein IQGAP1 | [127] | 1.18[128] | 0.77[129] | 1.12[130] | 3.19[131] | 3.00[132] | 1.28[133] |
20 | PAK4 | Serine/threonine-protein kinase PAK 4 | [134] | 0.22[135] | 0.30[136] | 0.93[137] | 0.24[138] | -0.07[139] | -1.08[140] |
21 | USP9X | Probable ubiquitin carboxyl-terminal hydrolase FAF-X | [141] | 1.17[142] | 1.93[143] | 2.70[144] | 2.94[145] | 2.82[146] | 3.45[147] |
22 | ZNF512B | Zinc finger protein 512B | [148] | 1.93[149] | 2.65[150] | -6.06[151] | 1.23[152] | -0.09[153] | 0.20[154] |
23 | GIT1 | ARF GTPase-activating protein GIT1 | [155] | 1.30[156] | 1.22[157] | 0.56[158] | 1.18[159] | 0.85[160] | -1.22[161] |
24 | ARHGEF7 | Rho guanine nucleotide exchange factor 7 | [162] | 0.94[163] | 0.98[164] | 0.77[165] | 1.03[166] | 0.75[167] | 1.60[168] |
25 | SH3RF1 | E3 ubiquitin-protein ligase SH3RF1 | [169] | 0.63[170] | -0.31[171] | 0.81[172] | -0.06[173] | 1.10[174] | 0.61[175] |
26 | PAK1 | Serine/threonine-protein kinase PAK 1 | [176] | -0.68[177] | -1.40[178] | 0.94[179] | -2.64[180] | 1.11[181] | -0.48[182] |
27 | DEPDC1B | DEP domain-containing protein 1B | [183] | 0.50[184] | 2.09[185] | 2.24[186] | 0.22[187] | 0.73[188] | -3.74[189] |
28 | DLG5 | Disks large homolog 5 | [190] | 2.58[191] | 2.72[192] | 1.98[193] | 2.38[194] | 2.49[195] | 0.20[196] |
29 | PARD6B | Partitioning defective 6 homolog beta | [197] | -0.29[198] | 0.66[199] | 1.20[200] | -0.94[201] | -2.06[202] | 1.37[203] |
30 | CCP110 | Centriolar coiled-coil protein of 110 kDa | [204] | 0.29[205] | 1.17[206] | -0.07[207] | 0.17[208] | 1.15[209] | 0.60[210] |
31 | PARD6A | Partitioning defective 6 homolog alpha | [211] | -1.08[212] | -1.08[213] | -4.14[214] | -1.97[215] | -3.01[216] | -1.89[217] |
32 | PEAK1 | Pseudopodium-enriched atypical kinase 1 | [218] | 1.45[219] | 1.97[220] | 2.60[221] | 2.52[222] | 3.00[223] | 2.03[224] |
33 | VANGL1 | Vang-like protein 1 | [225] | 2.29[226] | 1.78[227] | 1.14[228] | 3.43[229] | 3.07[230] | 1.95[231] |
34 | MYO9A | Unconventional myosin-IXa | [232] | 1.00[233] | 1.98[234] | 2.52[235] | 2.94[236] | 2.38[237] | 3.78[238] |
35 | CEP97 | Centrosomal protein of 97 kDa | [239] | -0.02[240] | 0.88[241] | 1.99[242] | 1.91[243] | 2.95[244] | 1.81[245] |
36 | PAK6 | Serine/threonine-protein kinase PAK 6 | [246] | -2.35[247] | [248] | 0.36[249] | 1.42[250] | 0.50[251] | -1.82[252] |
37 | RHOV | Rho-related GTP-binding protein RhoV | [253] | 1.42[254] | 0.97[255] | 2.24[256] | 1.97[257] | 0.07[258] | [259] |