REACTOME_RHOQ_GTPASE_CYCLE | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | CDC42 | Cell division control protein 42 homolog | [1] | -1.34[2] | -0.49[3] | -1.78[4] | -1.26[5] | -1.79[6] | -2.61[7] |
2 | RAB7A | Ras-related protein Rab-7a | [8] | -1.32[9] | -1.70[10] | -1.78[11] | -1.79[12] | -1.08[13] | -1.83[14] |
3 | STOM | Erythrocyte band 7 integral membrane protein | [15] | -1.85[16] | -1.56[17] | -1.43[18] | -1.79[19] | -2.99[20] | 0.71[21] |
4 | LAMTOR1 | Ragulator complex protein LAMTOR1 | [22] | -1.14[23] | -1.75[24] | -2.12[25] | -1.80[26] | -1.66[27] | -1.83[28] |
5 | STEAP3 | Metalloreductase STEAP3 | [29] | -1.99[30] | -2.57[31] | -5.04[32] | -2.11[33] | -2.83[34] | 1.18[35] |
6 | CDC42EP1 | Cdc42 effector protein 1 | [36] | -0.37[37] | -1.04[38] | -0.97[39] | -3.29[40] | -1.33[41] | -1.13[42] |
7 | CAV1 | Caveolin-1 | [43] | -7.35[44] | -10.05[45] | -4.05[46] | 0.65[47] | -0.52[48] | -2.52[49] |
8 | VAMP3 | Vesicle-associated membrane protein 3 | [50] | -0.29[51] | 0.39[52] | -0.69[53] | 0.00[54] | -0.27[55] | -1.54[56] |
9 | JUP | Junction plakoglobin | [57] | 0.47[58] | -0.61[59] | -0.61[60] | -1.28[61] | -1.78[62] | -0.11[63] |
10 | SNAP23 | Synaptosomal-associated protein 23 | [64] | -0.56[65] | -0.38[66] | -1.39[67] | -0.77[68] | -0.77[69] | -1.15[70] |
11 | TFRC | Transferrin receptor protein 1 | [71] | 2.92[72] | 2.55[73] | 2.39[74] | 0.73[75] | 2.39[76] | 1.05[77] |
12 | PAK2 | Serine/threonine-protein kinase PAK 2 | [78] | 0.93[79] | 0.81[80] | 0.83[81] | 0.03[82] | 0.76[83] | 0.84[84] |
13 | ITSN1 | Intersectin-1 | [85] | -0.63[86] | -0.38[87] | 0.10[88] | 0.29[89] | 0.73[90] | 1.20[91] |
14 | CDC42EP4 | Cdc42 effector protein 4 | [92] | 0.35[93] | -0.03[94] | -0.07[95] | -0.34[96] | -0.75[97] | -0.02[98] |
15 | WASL | Neural Wiskott-Aldrich syndrome protein | [99] | -1.00[100] | 0.21[101] | 0.33[102] | 0.38[103] | -0.28[104] | 0.61[105] |
16 | ARHGAP1 | Rho GTPase-activating protein 17 | [106] | -0.03[107] | 0.28[108] | -0.68[109] | -0.35[110] | -0.60[111] | -1.29[112] |
17 | TRIP10 | Cdc42-interacting protein 4 | [113] | 0.20[114] | 0.40[115] | 1.45[116] | -0.10[117] | 0.46[118] | -2.19[119] |
18 | CDC42BPB | Serine/threonine-protein kinase MRCK beta | [120] | 1.46[121] | 0.89[122] | 0.86[123] | 1.82[124] | 1.21[125] | 1.40[126] |
19 | SLC1A5 | Neutral amino acid transporter B(0) | [127] | 3.10[128] | 2.43[129] | 2.08[130] | 2.47[131] | 1.85[132] | -2.46[133] |
20 | RHOQ | Rho-related GTP-binding protein RhoQ | [134] | 0.15[135] | 0.44[136] | -0.91[137] | 0.04[138] | 1.08[139] | -0.24[140] |
21 | GOPC | Golgi-associated PDZ and coiled-coil motif-containing protein | [141] | 0.61[142] | 1.32[143] | 0.35[144] | 0.60[145] | 1.21[146] | 0.68[147] |
22 | GIT2 | ARF GTPase-activating protein GIT2 | [148] | -0.20[149] | 0.45[150] | -0.25[151] | 0.44[152] | 0.42[153] | 0.54[154] |
23 | FNBP1 | Formin-binding protein 1 | [155] | -0.76[156] | -0.16[157] | -0.48[158] | 0.62[159] | -0.63[160] | 0.09[161] |
24 | IQGAP1 | Ras GTPase-activating-like protein IQGAP1 | [162] | 1.34[163] | 1.02[164] | 1.15[165] | 3.25[166] | 3.27[167] | 1.50[168] |
25 | PAK4 | Serine/threonine-protein kinase PAK 4 | [169] | 0.37[170] | 0.55[171] | 0.97[172] | 0.30[173] | 0.21[174] | -0.85[175] |
26 | WWP2 | NEDD4-like E3 ubiquitin-protein ligase WWP2 | [176] | 1.23[177] | 1.36[178] | 0.84[179] | 0.02[180] | 0.22[181] | 0.55[182] |
27 | ARHGAP2 | Rho GTPase-activating protein 21 | [183] | 0.05[184] | 1.16[185] | 1.76[186] | 2.39[187] | 1.32[188] | 1.21[189] |
28 | ARHGAP3 | Rho GTPase-activating protein 35 | [190] | 1.82[191] | 2.09[192] | 2.35[193] | 2.01[194] | 1.77[195] | 2.74[196] |
29 | DLC1 | Rho GTPase-activating protein 7 | [197] | 1.79[198] | 1.58[199] | 0.62[200] | 0.15[201] | 0.82[202] | 1.88[203] |
30 | SCRIB | Protein scribble homolog | [204] | 1.66[205] | 1.12[206] | 1.27[207] | 1.26[208] | 0.73[209] | -0.06[210] |
31 | ARHGAP1 | Rho GTPase-activating protein 1 | [211] | 1.27[212] | 1.00[213] | 1.22[214] | -0.22[215] | 0.16[216] | 1.11[217] |
32 | ARHGAP5 | Rho GTPase-activating protein 5 | [218] | 1.89[219] | 1.63[220] | 4.65[221] | 1.85[222] | 1.62[223] | 2.62[224] |
33 | PLEKHG3 | Pleckstrin homology domain-containing family G member 3 | [225] | -0.73[226] | -0.36[227] | 0.12[228] | -0.46[229] | -1.09[230] | 0.28[231] |
34 | GIT1 | ARF GTPase-activating protein GIT1 | [232] | 1.45[233] | 1.46[234] | 0.59[235] | 1.24[236] | 1.12[237] | -0.99[238] |
35 | ARHGEF7 | Rho guanine nucleotide exchange factor 7 | [239] | 1.10[240] | 1.23[241] | 0.80[242] | 1.09[243] | 1.02[244] | 1.83[245] |
36 | CPNE8 | Copine-8 | [246] | -2.36[247] | -7.02[248] | 0.85[249] | 0.05[250] | 0.33[251] | 1.70[252] |
37 | PAK1 | Serine/threonine-protein kinase PAK 1 | [253] | -0.53[254] | -1.16[255] | 0.98[256] | -2.58[257] | 1.38[258] | -0.25[259] |
38 | DEPDC1B | DEP domain-containing protein 1B | [260] | 0.66[261] | 2.34[262] | 2.27[263] | 0.28[264] | 1.01[265] | -3.51[266] |
39 | CDC42BPA | Serine/threonine-protein kinase MRCK alpha | [267] | 0.25[268] | 1.39[269] | 1.27[270] | 2.87[271] | 1.74[272] | 3.24[273] |
40 | SRGAP2 | SLIT-ROBO Rho GTPase-activating protein 2 | [274] | 1.22[275] | 1.44[276] | 0.88[277] | 1.69[278] | 1.90[279] | -0.12[280] |
41 | CDC42EP2 | Cdc42 effector protein 2 | [281] | -0.07[282] | -0.67[283] | -0.37[284] | 0.15[285] | 0.95[286] | -1.54[287] |
42 | DIAPH3 | Protein diaphanous homolog 3 | [288] | -0.56[289] | 0.66[290] | 0.87[291] | 0.84[292] | 1.88[293] | -3.12[294] |
43 | ARL13B | ADP-ribosylation factor-like protein 13B | [295] | -0.79[296] | 0.49[297] | 0.88[298] | 0.10[299] | 0.98[300] | 0.35[301] |
44 | GFOD1 | Glucose-fructose oxidoreductase domain-containing protein 1 | [302] | -0.38[303] | -0.82[304] | -3.08[305] | -0.68[306] | -1.26[307] | 1.69[308] |
45 | SLC4A7 | Sodium bicarbonate cotransporter 3 | [309] | 1.48[310] | 2.22[311] | 3.27[312] | 3.45[313] | 2.51[314] | 1.34[315] |
46 | MPP7 | MAGUK p55 subfamily member 7 | [316] | -0.43[317] | 2.28[318] | -2.54[319] | 2.60[320] | -2.32[321] | 0.61[322] |
47 | GJA1 | Gap junction alpha-1 protein | [323] | -3.37[324] | -2.95[325] | 4.00[326] | 4.24[327] | 4.50[328] | -0.86[329] |
48 | ARHGAP2 | Rho GTPase-activating protein 26 | [330] | 2.14[331] | 2.62[332] | 0.86[333] | 1.07[334] | 1.23[335] | 1.75[336] |
49 | CDC42EP3 | Cdc42 effector protein 3 | [337] | -2.21[338] | -6.39[339] | -4.84[340] | 4.66[341] | 4.43[342] | 1.79[343] |
50 | VANGL1 | Vang-like protein 1 | [344] | 2.45[345] | 2.02[346] | 1.17[347] | 3.49[348] | 3.35[349] | 2.17[350] |
51 | ARHGEF9 | Rho guanine nucleotide exchange factor 9 | [351] | -1.96[352] | -3.03[353] | -8.59[354] | 1.45[355] | 1.64[356] | 1.83[357] |
52 | OPHN1 | Oligophrenin-1 | [358] | 1.19[359] | 1.35[360] | 1.65[361] | 2.46[362] | 1.22[363] | 4.22[364] |
53 | PREX1 | Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein | -0.93[365] | -6.62[366] | -4.59[367] | 4.39[368] | 2.92[369] | 3.68[370] | |
54 | IQGAP3 | Ras GTPase-activating-like protein IQGAP3 | [371] | 3.26[372] | 4.37[373] | 3.56[374] | 4.03[375] | 5.40[376] | 0.43[377] |
55 | ARHGAP3 | Rho GTPase-activating protein 32 | [378] | 3.21[379] | 3.14[380] | 1.93[381] | 3.75[382] | 2.50[383] | 3.65[384] |
56 | SYDE1 | Rho GTPase-activating protein SYDE1 | [385] | 3.67[386] | 1.93[387] | 2.44[388] | 3.74[389] | 4.93[390] | 1.63[391] |
57 | ARHGAP3 | Rho GTPase-activating protein 33 | [392] | 0.04[393] | 2.54[394] | 1.28[395] | 1.42[396] | 1.86[397] | 0.16[398] |
58 | OBSCN | Obscurin | [399] | 3.41[400] | 0.94[401] | 1.32[402] | 7.09[403] | 4.44[404] | 6.10[405] |
59 | CFTR | Cystic fibrosis transmembrane conductance regulator | [406] | -2.70[407] | -3.07[408] | 0.20[409] | 3.10[410] | -4.31[411] | 6.63[412] |