REACTOME_RHOJ_GTPASE_CYCLE | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | CDC42 | Cell division control protein 42 homolog | [1] | -1.35[2] | -0.53[3] | -1.87[4] | -1.21[5] | -1.75[6] | -2.66[7] |
2 | RAB7A | Ras-related protein Rab-7a | [8] | -1.33[9] | -1.74[10] | -1.87[11] | -1.75[12] | -1.03[13] | -1.88[14] |
3 | STOM | Erythrocyte band 7 integral membrane protein | [15] | -1.86[16] | -1.60[17] | -1.52[18] | -1.74[19] | -2.95[20] | 0.65[21] |
4 | LAMTOR1 | Ragulator complex protein LAMTOR1 | [22] | -1.15[23] | -1.79[24] | -2.21[25] | -1.76[26] | -1.62[27] | -1.88[28] |
5 | STEAP3 | Metalloreductase STEAP3 | [29] | -2.00[30] | -2.61[31] | -5.13[32] | -2.07[33] | -2.79[34] | 1.13[35] |
6 | CDC42EP1 | Cdc42 effector protein 1 | [36] | -0.38[37] | -1.08[38] | -1.07[39] | -3.25[40] | -1.29[41] | -1.18[42] |
7 | CAV1 | Caveolin-1 | [43] | -7.36[44] | -10.09[45] | -4.14[46] | 0.70[47] | -0.47[48] | -2.57[49] |
8 | VAMP3 | Vesicle-associated membrane protein 3 | [50] | -0.30[51] | 0.35[52] | -0.79[53] | 0.04[54] | -0.23[55] | -1.60[56] |
9 | JUP | Junction plakoglobin | [57] | 0.46[58] | -0.65[59] | -0.70[60] | -1.23[61] | -1.73[62] | -0.17[63] |
10 | SNAP23 | Synaptosomal-associated protein 23 | [64] | -0.57[65] | -0.42[66] | -1.49[67] | -0.73[68] | -0.73[69] | -1.20[70] |
11 | TFRC | Transferrin receptor protein 1 | [71] | 2.91[72] | 2.51[73] | 2.30[74] | 0.77[75] | 2.44[76] | 1.00[77] |
12 | PAK2 | Serine/threonine-protein kinase PAK 2 | [78] | 0.92[79] | 0.77[80] | 0.73[81] | 0.08[82] | 0.80[83] | 0.79[84] |
13 | TMPO | Lamina-associated polypeptide 2, isoform alpha | [85] | 0.42[86] | 1.30[87] | 1.24[88] | 1.48[89] | 1.55[90] | 0.22[91] |
14 | WASL | Neural Wiskott-Aldrich syndrome protein | [92] | -1.01[93] | 0.17[94] | 0.23[95] | 0.43[96] | -0.24[97] | 0.56[98] |
15 | FNBP1L | Formin-binding protein 1-like | [99] | 0.08[100] | 0.76[101] | 0.65[102] | 0.19[103] | -0.82[104] | -0.19[105] |
16 | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha | [106] | -1.00[107] | -0.78[108] | -0.02[109] | 1.39[110] | 1.07[111] | 2.43[112] |
17 | CDC42BPB | Serine/threonine-protein kinase MRCK beta | [113] | 1.45[114] | 0.86[115] | 0.76[116] | 1.86[117] | 1.25[118] | 1.35[119] |
18 | SLC1A5 | Neutral amino acid transporter B(0) | [120] | 3.09[121] | 2.39[122] | 1.99[123] | 2.52[124] | 1.89[125] | -2.51[126] |
19 | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta | [127] | 1.35[128] | 1.67[129] | 1.95[130] | 0.03[131] | 0.77[132] | -0.86[133] |
20 | GIT2 | ARF GTPase-activating protein GIT2 | [134] | -0.21[135] | 0.41[136] | -0.35[137] | 0.48[138] | 0.46[139] | 0.48[140] |
21 | FNBP1 | Formin-binding protein 1 | [141] | -0.77[142] | -0.20[143] | -0.58[144] | 0.67[145] | -0.59[146] | 0.04[147] |
22 | PAK4 | Serine/threonine-protein kinase PAK 4 | [148] | 0.36[149] | 0.51[150] | 0.87[151] | 0.34[152] | 0.25[153] | -0.90[154] |
23 | WIPF2 | WAS/WASL-interacting protein family member 2 | [155] | 1.16[156] | -0.16[157] | 0.60[158] | 0.60[159] | 0.23[160] | -0.24[161] |
24 | WWP2 | NEDD4-like E3 ubiquitin-protein ligase WWP2 | [162] | 1.22[163] | 1.32[164] | 0.75[165] | 0.06[166] | 0.26[167] | 0.50[168] |
25 | ARHGAP2 | Rho GTPase-activating protein 21 | [169] | 0.04[170] | 1.12[171] | 1.67[172] | 2.44[173] | 1.36[174] | 1.16[175] |
26 | ARHGAP3 | Rho GTPase-activating protein 35 | [176] | 1.81[177] | 2.05[178] | 2.26[179] | 2.06[180] | 1.81[181] | 2.69[182] |
27 | SCRIB | Protein scribble homolog | [183] | 1.65[184] | 1.08[185] | 1.18[186] | 1.30[187] | 0.77[188] | -0.11[189] |
28 | ARHGAP1 | Rho GTPase-activating protein 1 | [190] | 1.26[191] | 0.96[192] | 1.12[193] | -0.18[194] | 0.20[195] | 1.05[196] |
29 | TRIO | Triple functional domain protein | [197] | 1.47[198] | 1.31[199] | 1.22[200] | 1.93[201] | 2.99[202] | 2.18[203] |
30 | ARHGAP5 | Rho GTPase-activating protein 5 | [204] | 1.88[205] | 1.59[206] | 4.56[207] | 1.89[208] | 1.66[209] | 2.57[210] |
31 | GIT1 | ARF GTPase-activating protein GIT1 | [211] | 1.44[212] | 1.42[213] | 0.50[214] | 1.28[215] | 1.16[216] | -1.05[217] |
32 | OCRL | Inositol polyphosphate 5-phosphatase OCRL-1 | [218] | 1.54[219] | 1.95[220] | 2.09[221] | 1.72[222] | 1.82[223] | 0.69[224] |
33 | ARHGEF7 | Rho guanine nucleotide exchange factor 7 | [225] | 1.09[226] | 1.19[227] | 0.71[228] | 1.14[229] | 1.07[230] | 1.78[231] |
34 | CPNE8 | Copine-8 | [232] | -2.37[233] | -7.06[234] | 0.75[235] | 0.10[236] | 0.37[237] | 1.65[238] |
35 | PAK1 | Serine/threonine-protein kinase PAK 1 | [239] | -0.54[240] | -1.19[241] | 0.88[242] | -2.53[243] | 1.43[244] | -0.31[245] |
36 | DEPDC1B | DEP domain-containing protein 1B | [246] | 0.65[247] | 2.30[248] | 2.18[249] | 0.33[250] | 1.05[251] | -3.57[252] |
37 | CDC42BPA | Serine/threonine-protein kinase MRCK alpha | [253] | 0.24[254] | 1.35[255] | 1.18[256] | 2.92[257] | 1.78[258] | 3.19[259] |
38 | DIAPH3 | Protein diaphanous homolog 3 | [260] | -0.57[261] | 0.63[262] | 0.78[263] | 0.89[264] | 1.92[265] | -3.17[266] |
39 | ARL13B | ADP-ribosylation factor-like protein 13B | [267] | -0.80[268] | 0.45[269] | 0.78[270] | 0.14[271] | 1.02[272] | 0.30[273] |
40 | SLC4A7 | Sodium bicarbonate cotransporter 3 | [274] | 1.47[275] | 2.18[276] | 3.18[277] | 3.50[278] | 2.55[279] | 1.28[280] |
41 | MPP7 | MAGUK p55 subfamily member 7 | [281] | -0.44[282] | 2.24[283] | -2.63[284] | 2.65[285] | -2.28[286] | 0.56[287] |
42 | GJA1 | Gap junction alpha-1 protein | [288] | -3.38[289] | -2.99[290] | 3.91[291] | 4.28[292] | 4.54[293] | -0.92[294] |
43 | ARHGAP2 | Rho GTPase-activating protein 26 | [295] | 2.13[296] | 2.58[297] | 0.77[298] | 1.12[299] | 1.28[300] | 1.70[301] |
44 | WAS | Wiskott-Aldrich syndrome protein | [302] | -6.24[303] | -5.59[304] | -2.49[305] | -4.19[306] | -5.05[307] | -0.99[308] |
45 | VANGL1 | Vang-like protein 1 | [309] | 2.44[310] | 1.99[311] | 1.08[312] | 3.53[313] | 3.39[314] | 2.12[315] |
46 | DOCK8 | Dedicator of cytokinesis protein 8 | [316] | -1.68[317] | -3.41[318] | 1.66[319] | -3.24[320] | -4.58[321] | 3.07[322] |
47 | OPHN1 | Oligophrenin-1 | [323] | 1.18[324] | 1.31[325] | 1.55[326] | 2.51[327] | 1.26[328] | 4.17[329] |
48 | PREX1 | Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein | -0.94[330] | -6.66[331] | -4.69[332] | 4.43[333] | 2.96[334] | 3.63[335] | |
49 | IQGAP3 | Ras GTPase-activating-like protein IQGAP3 | [336] | 3.25[337] | 4.33[338] | 3.47[339] | 4.08[340] | 5.44[341] | 0.38[342] |
50 | ARHGAP3 | Rho GTPase-activating protein 32 | [343] | 3.20[344] | 3.10[345] | 1.84[346] | 3.79[347] | 2.54[348] | 3.60[349] |
51 | SYDE1 | Rho GTPase-activating protein SYDE1 | [350] | 3.66[351] | 1.89[352] | 2.35[353] | 3.79[354] | 4.97[355] | 1.58[356] |
52 | RHOJ | Rho-related GTP-binding protein RhoJ | [357] | -3.65[358] | -5.13[359] | -7.67[360] | -3.16[361] | -5.36[362] | 1.33[363] |
53 | FMNL3 | Formin-like protein 3 | [364] | 2.11[365] | 2.00[366] | 2.55[367] | 2.90[368] | 4.83[369] | 3.48[370] |
54 | PAK3 | Serine/threonine-protein kinase PAK 3 | [371] | -6.94[372] | [373] | [374] | -2.28[375] | -0.38[376] | 0.21[377] |
55 | NIPSNAP2 | Protein NipSnap homolog 2 | [378] | [379] | [380] | [381] | [382] | [383] | [384] |