REACTOME_RHOBTB2_GTPASE_CYCLE Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 ACTG1 Actin, cytoplasmic 2 [1] -0.08[2] -1.33[3] -0.99[4] -0.80[5] -0.31[6] -0.50[7]
2 HSP90AB1 Heat shock protein HSP 90-beta [8] 0.26[9] 0.43[10] -0.14[11] -0.16[12] -0.69[13] -0.67[14]
3 HSP90AA1 Heat shock protein HSP 90-alpha [15] -0.61[16] 0.43[17] -0.10[18] 0.48[19] 0.26[20] 0.17[21]
4 CCT7 T-complex protein 1 subunit eta [22] -0.02[23] -0.06[24] -0.27[25] -0.57[26] -0.38[27] -0.35[28]
5 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 [29] 0.76[30] 0.67[31] 1.43[32] 0.19[33] 0.76[34] 0.63[35]
6 CDC37 Hsp90 co-chaperone Cdc37 [36] -0.73[37] -1.31[38] -0.69[39] -1.42[40] -0.75[41] -0.55[42]
7 CCT2 T-complex protein 1 subunit beta [43] 0.00[44] 0.44[45] 0.56[46] 0.29[47] 0.45[48] 0.01[49]
8 CCT6A T-complex protein 1 subunit zeta [50] 0.45[51] 0.89[52] 1.37[53] 0.84[54] 0.73[55] 0.41[56]
9 TXNL1 Thioredoxin-like protein 1 [57] -1.71[58] -1.50[59] -1.42[60] -1.04[61] -1.19[62] -0.12[63]
10 DDX39B Spliceosome RNA helicase DDX39B [64] -9.92[65] -9.49[66] -9.77[67] -9.00[68] -8.05[69] -9.71[70]
11 ACTN1 Alpha-actinin-1 [71] 0.85[72] 0.04[73] -0.38[74] 2.10[75] 1.55[76] 1.47[77]
12 RBMX RNA-binding motif protein, X chromosome [78] -0.16[79] 0.51[80] 1.69[81] 0.06[82] -0.04[83] 0.58[84]
13 TWF1 Twinfilin-1 [85] -0.62[86] 1.01[87] 1.44[88] 1.05[89] 1.13[90] 1.46[91]
14 TRA2B Transformer-2 protein homolog beta [92] 0.59[93] 1.19[94] 1.12[95] 0.64[96] 1.11[97] 1.08[98]
15 SRRM1 Serine/arginine repetitive matrix protein 1 [99] 0.14[100] 1.72[101] 1.47[102] 1.21[103] 1.32[104] 2.06[105]
16 STK38 Serine/threonine-protein kinase 38 [106] 0.30[107] -0.04[108] -0.26[109] 2.23[110] 1.22[111] 2.00[112]
17 TMOD3 Tropomodulin-3 [113] 0.30[114] 0.74[115] 1.60[116] 1.87[117] 1.92[118] 2.58[119]
18 DBN1 Drebrin [120] 2.47[121] 1.50[122] 2.67[123] 2.73[124] 2.47[125] -0.99[126]
19 CUL3 Cullin-3 [127] 0.65[128] 1.63[129] 1.59[130] 1.85[131] 2.03[132] 2.37[133]
20 MYO6 Unconventional myosin-VI [134] 0.52[135] 1.72[136] 2.23[137] 1.51[138] 1.41[139] 3.70[140]
21 MSI2 RNA-binding protein Musashi homolog 2 [141] 1.76[142] 1.70[143] 1.89[144] -0.77[145] 0.83[146] 0.55[147]
22 PHIP PH-interacting protein [148] 1.68[149] 4.00[150] 4.38[151] 3.77[152] 3.82[153] 5.29[154]
23 RHOBTB2 Rho-related BTB domain-containing protein 2 [155] 3.13[156] 2.73[157] 1.93[158] 2.42[159] 2.99[160] 2.88[161]
[1]
ref_hepatocyte ACTG1
Mean 733
Standard deviation 4e+02
Values 1.1e+03 1e+03 9.5e+02 3.5e+02 2.4e+02
[2]
HepG2 ACTG1
Mean 1.5e+03
Standard deviation 1.8e+02
Values 1.6e+03 1.4e+03
[3]
HepG2.C3A ACTG1
Mean 534
Standard deviation 1.5e+02
Values 6.4e+02 4.3e+02
[4]
HuH.7 ACTG1
Mean 549
Standard deviation 1.6e+02
Values 6.7e+02 3.7e+02 6e+02
[5]
SNU475 ACTG1
Mean 591
Standard deviation 2.2e+02
Values 7.5e+02 4.3e+02
[6]
THLE ACTG1
Mean 872
Standard deviation 1.9e+02
Values 7.3e+02 1e+03
[7]
liver ACTG1
Mean 273
Standard deviation 78
Values 3.2e+02 1.9e+02 3.6e+02 2.2e+02
[8]
ref_hepatocyte HSP90AB1
Mean 469
Standard deviation 3.2e+02
Values 8.1e+02 7.8e+02 4e+02 2.1e+02 1.4e+02
[9]
HepG2 HSP90AB1
Mean 1.22e+03
Standard deviation 89
Values 1.2e+03 1.3e+03
[10]
HepG2.C3A HSP90AB1
Mean 1.16e+03
Standard deviation 1.2e+02
Values 1.2e+03 1.1e+03
[11]
HuH.7 HSP90AB1
Mean 634
Standard deviation 9.5
Values 6.3e+02 6.2e+02 6.4e+02
[12]
SNU475 HSP90AB1
Mean 591
Standard deviation 65
Values 5.4e+02 6.4e+02
[13]
THLE HSP90AB1
Mean 431
Standard deviation 80
Values 3.7e+02 4.9e+02
[14]
liver HSP90AB1
Mean 156
Standard deviation 26
Values 1.5e+02 1.4e+02 1.9e+02 1.3e+02
[15]
ref_hepatocyte HSP90AA1
Mean 356
Standard deviation 2.5e+02
Values 5.4e+02 6.9e+02 1.3e+02 2.5e+02 1.7e+02
[16]
HepG2 HSP90AA1
Mean 503
Standard deviation 2.6e+02
Values 3.2e+02 6.9e+02
[17]
HepG2.C3A HSP90AA1
Mean 878
Standard deviation 5.2e+02
Values 5.1e+02 1.2e+03
[18]
HuH.7 HSP90AA1
Mean 494
Standard deviation 76
Values 5.4e+02 4.1e+02 5.4e+02
[19]
SNU475 HSP90AA1
Mean 696
Standard deviation 1.5e+02
Values 5.9e+02 8e+02
[20]
THLE HSP90AA1
Mean 627
Standard deviation 16
Values 6.4e+02 6.2e+02
[21]
liver HSP90AA1
Mean 212
Standard deviation 50
Values 2.7e+02 1.9e+02 2.4e+02 1.6e+02
[22]
ref_hepatocyte CCT7
Mean 119
Standard deviation 67
Values 1.9e+02 1.9e+02 97 75 45
[23]
HepG2 CCT7
Mean 254
Standard deviation 13
Values 2.6e+02 2.5e+02
[24]
HepG2.C3A CCT7
Mean 209
Standard deviation 26
Values 1.9e+02 2.3e+02
[25]
HuH.7 CCT7
Mean 147
Standard deviation 41
Values 1.6e+02 1e+02 1.8e+02
[26]
SNU475 CCT7
Mean 113
Standard deviation 15
Values 1e+02 1.2e+02
[27]
THLE CCT7
Mean 135
Standard deviation 24
Values 1.2e+02 1.5e+02
[28]
liver CCT7
Mean 49.4
Standard deviation 15
Values 60 40 64 33
[29]
ref_hepatocyte HNRNPC
Mean 107
Standard deviation 35
Values 76 1.5e+02 1.4e+02 88 82
[30]
HepG2 HNRNPC
Mean 392
Standard deviation 13
Values 3.8e+02 4e+02
[31]
HepG2.C3A HNRNPC
Mean 312
Standard deviation 1.3e+02
Values 2.2e+02 4e+02
[32]
HuH.7 HNRNPC
Mean 431
Standard deviation 93
Values 4.3e+02 3.4e+02 5.2e+02
[33]
SNU475 HNRNPC
Mean 172
Standard deviation 57
Values 2.1e+02 1.3e+02
[34]
THLE HNRNPC
Mean 268
Standard deviation 55
Values 2.3e+02 3.1e+02
[35]
liver HNRNPC
Mean 87.8
Standard deviation 25
Values 86 96 1.1e+02 55
[36]
ref_hepatocyte CDC37
Mean 77.7
Standard deviation 56
Values 42 1.3e+02 1.5e+02 40 29
[37]
HepG2 CDC37
Mean 102
Standard deviation 8.8
Values 1.1e+02 95
[38]
HepG2.C3A CDC37
Mean 57.6
Standard deviation 0.71
Values 57 58
[39]
HuH.7 CDC37
Mean 71.5
Standard deviation 19
Values 75 51 88
[40]
SNU475 CDC37
Mean 40.8
Standard deviation 3.1
Values 39 43
[41]
THLE CDC37
Mean 68.3
Standard deviation 6.1
Values 64 73
[42]
liver CDC37
Mean 28
Standard deviation 16
Values 40 14 45 13
[43]
ref_hepatocyte CCT2
Mean 60.7
Standard deviation 45
Values 48 1.4e+02 54 40 24
[44]
HepG2 CCT2
Mean 131
Standard deviation 14
Values 1.2e+02 1.4e+02
[45]
HepG2.C3A CCT2
Mean 151
Standard deviation 40
Values 1.2e+02 1.8e+02
[46]
HuH.7 CCT2
Mean 133
Standard deviation 26
Values 1.4e+02 1.1e+02 1.6e+02
[47]
SNU475 CCT2
Mean 105
Standard deviation 14
Values 95 1.1e+02
[48]
THLE CCT2
Mean 122
Standard deviation 20
Values 1.1e+02 1.4e+02
[49]
liver CCT2
Mean 32.3
Standard deviation 16
Values 47 22 44 16
[50]
ref_hepatocyte CCT6A
Mean 53.7
Standard deviation 30
Values 64 1e+02 46 32 25
[51]
HepG2 CCT6A
Mean 159
Standard deviation 31
Values 1.4e+02 1.8e+02
[52]
HepG2.C3A CCT6A
Mean 183
Standard deviation 57
Values 1.4e+02 2.2e+02
[53]
HuH.7 CCT6A
Mean 206
Standard deviation 42
Values 2.4e+02 1.6e+02 2.3e+02
[54]
SNU475 CCT6A
Mean 135
Standard deviation 13
Values 1.3e+02 1.4e+02
[55]
THLE CCT6A
Mean 131
Standard deviation 24
Values 1.1e+02 1.5e+02
[56]
liver CCT6A
Mean 37.6
Standard deviation 17
Values 45 28 58 20
[57]
ref_hepatocyte TXNL1
Mean 47.4
Standard deviation 8.3
Values 35 57 53 45 47
[58]
HepG2 TXNL1
Mean 31.3
Standard deviation 3.9
Values 29 34
[59]
HepG2.C3A TXNL1
Mean 30.7
Standard deviation 1
Values 31 30
[60]
HuH.7 TXNL1
Mean 26.3
Standard deviation 3.2
Values 24 30 25
[61]
SNU475 TXNL1
Mean 32.4
Standard deviation 0.76
Values 32 33
[62]
THLE TXNL1
Mean 30.6
Standard deviation 3.3
Values 28 33
[63]
liver TXNL1
Mean 23
Standard deviation 18
Values 41 9.4 35 6.6
[64]
ref_hepatocyte DDX39B
Mean 44.2
Standard deviation 17
Values 68 51 22 41 39
[65]
HepG2 DDX39B
Mean 0.0987
Standard deviation 0.067
Values 0.052 0.15
[66]
HepG2.C3A DDX39B
Mean 0.112
Standard deviation 0.0078
Values 0.11 0.12
[67]
HuH.7 DDX39B
Mean 0.0752
Standard deviation 0.044
Values 0.082 0.12 0.028
[68]
SNU475 DDX39B
Mean 0.121
Standard deviation 0.0061
Values 0.13 0.12
[69]
THLE DDX39B
Mean 0.246
Standard deviation 0.088
Values 0.18 0.31
[70]
liver DDX39B
Mean 0.0278
Standard deviation 0.04
Values 0 0.086 0.026 0
[71]
ref_hepatocyte ACTN1
Mean 41
Standard deviation 28
Values 17 82 59 26 20
[72]
HepG2 ACTN1
Mean 160
Standard deviation 12
Values 1.7e+02 1.5e+02
[73]
HepG2.C3A ACTN1
Mean 77.3
Standard deviation 10
Values 85 70
[74]
HuH.7 ACTN1
Mean 46.8
Standard deviation 15
Values 62 32 46
[75]
SNU475 ACTN1
Mean 246
Standard deviation 54
Values 2.8e+02 2.1e+02
[76]
THLE ACTN1
Mean 177
Standard deviation 43
Values 1.5e+02 2.1e+02
[77]
liver ACTN1
Mean 59.6
Standard deviation 20
Values 44 54 89 51
[78]
ref_hepatocyte RBMX
Mean 36.8
Standard deviation 17
Values 55 49 42 17 21
[79]
HepG2 RBMX
Mean 71
Standard deviation 5.9
Values 67 75
[80]
HepG2.C3A RBMX
Mean 95.8
Standard deviation 1
Values 97 95
[81]
HuH.7 RBMX
Mean 176
Standard deviation 21
Values 2e+02 1.5e+02 1.8e+02
[82]
SNU475 RBMX
Mean 53.9
Standard deviation 3.5
Values 51 56
[83]
THLE RBMX
Mean 52.9
Standard deviation 7.6
Values 48 58
[84]
liver RBMX
Mean 28.9
Standard deviation 5.9
Values 26 29 37 23
[85]
ref_hepatocyte TWF1
Mean 20.8
Standard deviation 10
Values 25 37 15 11 17
[86]
HepG2 TWF1
Mean 29.3
Standard deviation 12
Values 21 38
[87]
HepG2.C3A TWF1
Mean 76.6
Standard deviation 24
Values 60 93
[88]
HuH.7 TWF1
Mean 84
Standard deviation 8.8
Values 84 93 75
[89]
SNU475 TWF1
Mean 60.6
Standard deviation 2.7
Values 59 63
[90]
THLE TWF1
Mean 66.9
Standard deviation 1.3
Values 68 66
[91]
liver TWF1
Mean 30.2
Standard deviation 10
Values 36 30 39 16
[92]
ref_hepatocyte TRA2B
Mean 20.5
Standard deviation 9.1
Values 30 29 22 10 12
[93]
HepG2 TRA2B
Mean 66.7
Standard deviation 16
Values 55 78
[94]
HepG2.C3A TRA2B
Mean 85.7
Standard deviation 36
Values 60 1.1e+02
[95]
HuH.7 TRA2B
Mean 66
Standard deviation 25
Values 72 39 87
[96]
SNU475 TRA2B
Mean 44.9
Standard deviation 4.2
Values 42 48
[97]
THLE TRA2B
Mean 65.2
Standard deviation 13
Values 56 74
[98]
liver TRA2B
Mean 22.8
Standard deviation 1.2
Values 22 23 24 21
[99]
ref_hepatocyte SRRM1
Mean 9.87
Standard deviation 5.3
Values 18 8.7 12 5 5.6
[100]
HepG2 SRRM1
Mean 23.5
Standard deviation 1.5
Values 22 25
[101]
HepG2.C3A SRRM1
Mean 59.7
Standard deviation 18
Values 73 47
[102]
HuH.7 SRRM1
Mean 40.5
Standard deviation 3.1
Values 42 42 37
[103]
SNU475 SRRM1
Mean 32.2
Standard deviation 6.5
Values 37 28
[104]
THLE SRRM1
Mean 36.2
Standard deviation 3.2
Values 34 39
[105]
liver SRRM1
Mean 21.7
Standard deviation 16
Values 39 9.1 32 7.6
[106]
ref_hepatocyte STK38
Mean 7.54
Standard deviation 4.4
Values 14 10 2.6 6.9 4.4
[107]
HepG2 STK38
Mean 20
Standard deviation 4
Values 17 23
[108]
HepG2.C3A STK38
Mean 13.4
Standard deviation 0.29
Values 13 14
[109]
HuH.7 STK38
Mean 9.32
Standard deviation 0.36
Values 9 9.7 9.3
[110]
SNU475 STK38
Mean 49.6
Standard deviation 10
Values 57 42
[111]
THLE STK38
Mean 26
Standard deviation 2.1
Values 24 27
[112]
liver STK38
Mean 15.9
Standard deviation 1.5
Values 16 14 17 16
[113]
ref_hepatocyte TMOD3
Mean 7.51
Standard deviation 3.8
Values 11 12 6.8 3.9 4
[114]
HepG2 TMOD3
Mean 20
Standard deviation 3.2
Values 18 22
[115]
HepG2.C3A TMOD3
Mean 22.9
Standard deviation 3.6
Values 20 26
[116]
HuH.7 TMOD3
Mean 33.9
Standard deviation 8
Values 42 33 27
[117]
SNU475 TMOD3
Mean 38.4
Standard deviation 5.9
Values 43 34
[118]
THLE TMOD3
Mean 41.9
Standard deviation 5
Values 38 45
[119]
liver TMOD3
Mean 23.6
Standard deviation 6.8
Values 19 27 31 17
[120]
ref_hepatocyte DBN1
Mean 6.29
Standard deviation 6.3
Values 12 14 4.2 0.15 1.2
[121]
HepG2 DBN1
Mean 75.2
Standard deviation 18
Values 88 62
[122]
HepG2.C3A DBN1
Mean 32.7
Standard deviation 3.5
Values 35 30
[123]
HuH.7 DBN1
Mean 59.7
Standard deviation 22
Values 74 35 70
[124]
SNU475 DBN1
Mean 58.8
Standard deviation 2.4
Values 60 57
[125]
THLE DBN1
Mean 51.6
Standard deviation 3
Values 49 54
[126]
liver DBN1
Mean 1.67
Standard deviation 0.58
Values 2 0.96 2.3 1.5
[127]
ref_hepatocyte CUL3
Mean 5.91
Standard deviation 1.6
Values 7.2 7.4 3.5 5.4 6
[128]
HepG2 CUL3
Mean 20
Standard deviation 5.9
Values 16 24
[129]
HepG2.C3A CUL3
Mean 33.5
Standard deviation 2.3
Values 32 35
[130]
HuH.7 CUL3
Mean 26.4
Standard deviation 3
Values 29 23 27
[131]
SNU475 CUL3
Mean 29.9
Standard deviation 0.9
Values 29 31
[132]
THLE CUL3
Mean 35.6
Standard deviation 0.55
Values 35 36
[133]
liver CUL3
Mean 16.1
Standard deviation 5.2
Values 15 20 9.1 20
[134]
ref_hepatocyte MYO6
Mean 4.14
Standard deviation 2.1
Values 5.9 6.2 4.6 1.5 2.5
[135]
HepG2 MYO6
Mean 12.8
Standard deviation 1.3
Values 12 14
[136]
HepG2.C3A MYO6
Mean 25
Standard deviation 2.5
Values 27 23
[137]
HuH.7 MYO6
Mean 28.9
Standard deviation 4.2
Values 29 33 24
[138]
SNU475 MYO6
Mean 16.6
Standard deviation 3.3
Values 19 14
[139]
THLE MYO6
Mean 16.2
Standard deviation 2.4
Values 18 15
[140]
liver MYO6
Mean 28.4
Standard deviation 9.3
Values 41 26 29 18
[141]
ref_hepatocyte MSI2
Mean 2.55
Standard deviation 2.1
Values 6.1 2.8 0.99 1.9 0.99
[142]
HepG2 MSI2
Mean 18.7
Standard deviation 2
Values 17 20
[143]
HepG2.C3A MSI2
Mean 15.2
Standard deviation 5.1
Values 12 19
[144]
HuH.7 MSI2
Mean 14
Standard deviation 4.9
Values 18 15 8.6
[145]
SNU475 MSI2
Mean 2.1
Standard deviation 0.07
Values 2.2 2.1
[146]
THLE MSI2
Mean 6.69
Standard deviation 0.9
Values 6.1 7.3
[147]
liver MSI2
Mean 1.97
Standard deviation 1.3
Values 0.96 3 0.72 3.2
[148]
ref_hepatocyte PHIP
Mean 1.22
Standard deviation 1.1
Values 3.1 1.3 0.44 0.35 0.98
[149]
HepG2 PHIP
Mean 8.43
Standard deviation 3.6
Values 5.9 11
[150]
HepG2.C3A PHIP
Mean 35.9
Standard deviation 8.3
Values 30 42
[151]
HuH.7 PHIP
Mean 37.8
Standard deviation 11
Values 40 48 25
[152]
SNU475 PHIP
Mean 23.5
Standard deviation 5.4
Values 20 27
[153]
THLE PHIP
Mean 25.4
Standard deviation 7.1
Values 30 20
[154]
liver PHIP
Mean 25.3
Standard deviation 6
Values 27 32 17 25
[155]
ref_hepatocyte RHOBTB2
Mean 0.713
Standard deviation 0.23
Values 0.99 0.53 0.61 0.93 0.5
[156]
HepG2 RHOBTB2
Mean 13.5
Standard deviation 0.24
Values 13 14
[157]
HepG2.C3A RHOBTB2
Mean 8.7
Standard deviation 0.4
Values 8.4 9
[158]
HuH.7 RHOBTB2
Mean 4.04
Standard deviation 0.33
Values 4.2 4.3 3.7
[159]
SNU475 RHOBTB2
Mean 5.35
Standard deviation 0.74
Values 4.8 5.9
[160]
THLE RHOBTB2
Mean 8.33
Standard deviation 0.36
Values 8.1 8.6
[161]
liver RHOBTB2
Mean 2.77
Standard deviation 0.97
Values 3.1 2.7 1.5 3.8