REACTOME_RHOBTB1_GTPASE_CYCLE Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CCT7 T-complex protein 1 subunit eta [1] -0.20[2] -0.55[3] -1.09[4] -1.60[5] -1.31[6] -1.25[7]
2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 [8] 0.57[9] 0.18[10] 0.61[11] -0.84[12] -0.17[13] -0.27[14]
3 CCT2 T-complex protein 1 subunit beta [15] -0.18[16] -0.04[17] -0.26[18] -0.74[19] -0.48[20] -0.89[21]
4 VIM Vimentin [22] -8.50[23] -9.17[24] -3.61[25] 1.95[26] 1.57[27] -0.72[28]
5 TXNL1 Thioredoxin-like protein 1 [29] -1.89[30] -1.98[31] -2.24[32] -2.07[33] -2.12[34] -1.02[35]
6 RBMX RNA-binding motif protein, X chromosome [36] -0.35[37] 0.02[38] 0.87[39] -0.97[40] -0.96[41] -0.33[42]
7 GPS1 COP9 signalosome complex subunit 1 [43] 0.43[44] 0.21[45] -0.64[46] -0.83[47] -0.71[48] 0.34[49]
8 TRA2B Transformer-2 protein homolog beta [50] 0.41[51] 0.71[52] 0.30[53] -0.39[54] 0.19[55] 0.18[56]
9 COPS2 COP9 signalosome complex subunit 2 [57] -0.98[58] 0.78[59] 0.91[60] -0.33[61] 0.08[62] 0.13[63]
10 SRRM1 Serine/arginine repetitive matrix protein 1 [64] -0.04[65] 1.24[66] 0.65[67] 0.18[68] 0.39[69] 1.16[70]
11 COPS4 COP9 signalosome complex subunit 4 [71] -0.68[72] 0.08[73] -0.13[74] -0.82[75] -0.38[76] 0.09[77]
12 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 [78] 0.58[79] 0.57[80] 0.98[81] 0.37[82] 0.79[83] 0.91[84]
13 STK38 Serine/threonine-protein kinase 38 [85] 0.11[86] -0.52[87] -1.08[88] 1.20[89] 0.30[90] 1.10[91]
14 RNF20 E3 ubiquitin-protein ligase BRE1A [92] 0.31[93] -0.21[94] 0.02[95] 0.25[96] 0.66[97] 1.01[98]
15 ROCK1 Rho-associated protein kinase 1 [99] -1.11[100] 0.19[101] 0.87[102] 0.72[103] 0.26[104] 2.11[105]
16 DBN1 Drebrin [106] 2.28[107] 1.02[108] 1.85[109] 1.70[110] 1.55[111] -1.89[112]
17 CUL3 Cullin-3 [113] 0.46[114] 1.15[115] 0.77[116] 0.82[117] 1.10[118] 1.47[119]
18 ROCK2 Rho-associated protein kinase 2 [120] 1.32[121] 2.33[122] 0.71[123] 1.99[124] -0.04[125] 2.45[126]
19 RBBP6 E3 ubiquitin-protein ligase RBBP6 [127] 0.50[128] 1.29[129] 0.62[130] 0.25[131] 0.84[132] 1.62[133]
20 MYO6 Unconventional myosin-VI [134] 0.33[135] 1.24[136] 1.41[137] 0.48[138] 0.48[139] 2.80[140]
21 RHOBTB1 Rho-related BTB domain-containing protein 1 [141] 2.68[142] 2.19[143] 0.75[144] 0.35[145] -0.60[146] 1.39[147]
22 SPEN Msx2-interacting protein [148] 2.73[149] 3.20[150] 2.97[151] 2.90[152] 3.09[153] 4.17[154]
23 PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase [155] -0.26[156] 0.81[157] 2.51[158] 3.29[159] 1.77[160] 3.51[161]
[1]
ref_hepatocyte CCT7
Mean 119
Standard deviation 67
Values 1.9e+02 1.9e+02 97 75 45
[2]
HepG2 CCT7
Mean 254
Standard deviation 13
Values 2.6e+02 2.5e+02
[3]
HepG2.C3A CCT7
Mean 209
Standard deviation 26
Values 1.9e+02 2.3e+02
[4]
HuH.7 CCT7
Mean 147
Standard deviation 41
Values 1.6e+02 1e+02 1.8e+02
[5]
SNU475 CCT7
Mean 113
Standard deviation 15
Values 1e+02 1.2e+02
[6]
THLE CCT7
Mean 135
Standard deviation 24
Values 1.2e+02 1.5e+02
[7]
liver CCT7
Mean 49.4
Standard deviation 15
Values 60 40 64 33
[8]
ref_hepatocyte HNRNPC
Mean 107
Standard deviation 35
Values 76 1.5e+02 1.4e+02 88 82
[9]
HepG2 HNRNPC
Mean 392
Standard deviation 13
Values 3.8e+02 4e+02
[10]
HepG2.C3A HNRNPC
Mean 312
Standard deviation 1.3e+02
Values 2.2e+02 4e+02
[11]
HuH.7 HNRNPC
Mean 431
Standard deviation 93
Values 4.3e+02 3.4e+02 5.2e+02
[12]
SNU475 HNRNPC
Mean 172
Standard deviation 57
Values 2.1e+02 1.3e+02
[13]
THLE HNRNPC
Mean 268
Standard deviation 55
Values 2.3e+02 3.1e+02
[14]
liver HNRNPC
Mean 87.8
Standard deviation 25
Values 86 96 1.1e+02 55
[15]
ref_hepatocyte CCT2
Mean 60.7
Standard deviation 45
Values 48 1.4e+02 54 40 24
[16]
HepG2 CCT2
Mean 131
Standard deviation 14
Values 1.2e+02 1.4e+02
[17]
HepG2.C3A CCT2
Mean 151
Standard deviation 40
Values 1.2e+02 1.8e+02
[18]
HuH.7 CCT2
Mean 133
Standard deviation 26
Values 1.4e+02 1.1e+02 1.6e+02
[19]
SNU475 CCT2
Mean 105
Standard deviation 14
Values 95 1.1e+02
[20]
THLE CCT2
Mean 122
Standard deviation 20
Values 1.1e+02 1.4e+02
[21]
liver CCT2
Mean 32.3
Standard deviation 16
Values 47 22 44 16
[22]
ref_hepatocyte VIM
Mean 54.6
Standard deviation 63
Values 0.056 1.2e+02 1.3e+02 12 14
[23]
HepG2 VIM
Mean 0.371
Standard deviation 0.34
Values 0.61 0.13
[24]
HepG2.C3A VIM
Mean 0.244
Standard deviation 0.11
Values 0.17 0.32
[25]
HuH.7 VIM
Mean 11.7
Standard deviation 9.3
Values 7.7 22 5.1
[26]
SNU475 VIM
Mean 609
Standard deviation 37
Values 6.4e+02 5.8e+02
[27]
THLE VIM
Mean 455
Standard deviation 1.6e+02
Values 3.4e+02 5.7e+02
[28]
liver VIM
Mean 32.8
Standard deviation 5.9
Values 37 35 35 24
[29]
ref_hepatocyte TXNL1
Mean 47.4
Standard deviation 8.3
Values 35 57 53 45 47
[30]
HepG2 TXNL1
Mean 31.3
Standard deviation 3.9
Values 29 34
[31]
HepG2.C3A TXNL1
Mean 30.7
Standard deviation 1
Values 31 30
[32]
HuH.7 TXNL1
Mean 26.3
Standard deviation 3.2
Values 24 30 25
[33]
SNU475 TXNL1
Mean 32.4
Standard deviation 0.76
Values 32 33
[34]
THLE TXNL1
Mean 30.6
Standard deviation 3.3
Values 28 33
[35]
liver TXNL1
Mean 23
Standard deviation 18
Values 41 9.4 35 6.6
[36]
ref_hepatocyte RBMX
Mean 36.8
Standard deviation 17
Values 55 49 42 17 21
[37]
HepG2 RBMX
Mean 71
Standard deviation 5.9
Values 67 75
[38]
HepG2.C3A RBMX
Mean 95.8
Standard deviation 1
Values 97 95
[39]
HuH.7 RBMX
Mean 176
Standard deviation 21
Values 2e+02 1.5e+02 1.8e+02
[40]
SNU475 RBMX
Mean 53.9
Standard deviation 3.5
Values 51 56
[41]
THLE RBMX
Mean 52.9
Standard deviation 7.6
Values 48 58
[42]
liver RBMX
Mean 28.9
Standard deviation 5.9
Values 26 29 37 23
[43]
ref_hepatocyte GPS1
Mean 21.1
Standard deviation 9
Values 20 11 14 30 31
[44]
HepG2 GPS1
Mean 70
Standard deviation 0.92
Values 71 69
[45]
HepG2.C3A GPS1
Mean 62.8
Standard deviation 6.9
Values 68 58
[46]
HuH.7 GPS1
Mean 35.5
Standard deviation 12
Values 39 22 45
[47]
SNU475 GPS1
Mean 34.2
Standard deviation 1.5
Values 33 35
[48]
THLE GPS1
Mean 36.2
Standard deviation 3.1
Values 34 38
[49]
liver GPS1
Mean 26.5
Standard deviation 12
Values 38 15 35 18
[50]
ref_hepatocyte TRA2B
Mean 20.5
Standard deviation 9.1
Values 30 29 22 10 12
[51]
HepG2 TRA2B
Mean 66.7
Standard deviation 16
Values 55 78
[52]
HepG2.C3A TRA2B
Mean 85.7
Standard deviation 36
Values 60 1.1e+02
[53]
HuH.7 TRA2B
Mean 66
Standard deviation 25
Values 72 39 87
[54]
SNU475 TRA2B
Mean 44.9
Standard deviation 4.2
Values 42 48
[55]
THLE TRA2B
Mean 65.2
Standard deviation 13
Values 56 74
[56]
liver TRA2B
Mean 22.8
Standard deviation 1.2
Values 22 23 24 21
[57]
ref_hepatocyte COPS2
Mean 14.9
Standard deviation 6.3
Values 20 23 13 8.9 9.3
[58]
HepG2 COPS2
Mean 18.5
Standard deviation 5.5
Values 15 22
[59]
HepG2.C3A COPS2
Mean 65.2
Standard deviation 12
Values 57 73
[60]
HuH.7 COPS2
Mean 73.2
Standard deviation 21
Values 70 96 54
[61]
SNU475 COPS2
Mean 34
Standard deviation 4.2
Values 31 37
[62]
THLE COPS2
Mean 44.2
Standard deviation 5.6
Values 48 40
[63]
liver COPS2
Mean 16
Standard deviation 2.1
Values 17 18 16 13
[64]
ref_hepatocyte SRRM1
Mean 9.87
Standard deviation 5.3
Values 18 8.7 12 5 5.6
[65]
HepG2 SRRM1
Mean 23.5
Standard deviation 1.5
Values 22 25
[66]
HepG2.C3A SRRM1
Mean 59.7
Standard deviation 18
Values 73 47
[67]
HuH.7 SRRM1
Mean 40.5
Standard deviation 3.1
Values 42 42 37
[68]
SNU475 SRRM1
Mean 32.2
Standard deviation 6.5
Values 37 28
[69]
THLE SRRM1
Mean 36.2
Standard deviation 3.2
Values 34 39
[70]
liver SRRM1
Mean 21.7
Standard deviation 16
Values 39 9.1 32 7.6
[71]
ref_hepatocyte COPS4
Mean 9.38
Standard deviation 2.5
Values 8.2 10 5.9 9.7 13
[72]
HepG2 COPS4
Mean 14.4
Standard deviation 3.5
Values 12 17
[73]
HepG2.C3A COPS4
Mean 25.3
Standard deviation 3.9
Values 23 28
[74]
HuH.7 COPS4
Mean 22.5
Standard deviation 0.33
Values 22 23 22
[75]
SNU475 COPS4
Mean 15.3
Standard deviation 1.1
Values 16 15
[76]
THLE COPS4
Mean 20.2
Standard deviation 1.4
Values 19 21
[77]
liver COPS4
Mean 9.82
Standard deviation 5.8
Values 12 6.4 17 3.9
[78]
ref_hepatocyte CPSF7
Mean 9.06
Standard deviation 2.5
Values 11 6.6 12 7 8.3
[79]
HepG2 CPSF7
Mean 33.2
Standard deviation 3.6
Values 31 36
[80]
HepG2.C3A CPSF7
Mean 34.4
Standard deviation 1.7
Values 33 36
[81]
HuH.7 CPSF7
Mean 46.7
Standard deviation 9.6
Values 53 36 51
[82]
SNU475 CPSF7
Mean 33.6
Standard deviation 2.1
Values 32 35
[83]
THLE CPSF7
Mean 44
Standard deviation 0.59
Values 44 44
[84]
liver CPSF7
Mean 16.7
Standard deviation 6.5
Values 18 11 25 12
[85]
ref_hepatocyte STK38
Mean 7.54
Standard deviation 4.4
Values 14 10 2.6 6.9 4.4
[86]
HepG2 STK38
Mean 20
Standard deviation 4
Values 17 23
[87]
HepG2.C3A STK38
Mean 13.4
Standard deviation 0.29
Values 13 14
[88]
HuH.7 STK38
Mean 9.32
Standard deviation 0.36
Values 9 9.7 9.3
[89]
SNU475 STK38
Mean 49.6
Standard deviation 10
Values 57 42
[90]
THLE STK38
Mean 26
Standard deviation 2.1
Values 24 27
[91]
liver STK38
Mean 15.9
Standard deviation 1.5
Values 16 14 17 16
[92]
ref_hepatocyte RNF20
Mean 6.84
Standard deviation 4.3
Values 11 12 2.8 3.8 4.7
[93]
HepG2 RNF20
Mean 20.9
Standard deviation 4.9
Values 17 24
[94]
HepG2.C3A RNF20
Mean 15.2
Standard deviation 1.1
Values 14 16
[95]
HuH.7 RNF20
Mean 18.1
Standard deviation 1.1
Values 19 18 17
[96]
SNU475 RNF20
Mean 23.3
Standard deviation 1.5
Values 24 22
[97]
THLE RNF20
Mean 30.4
Standard deviation 1.3
Values 29 31
[98]
liver RNF20
Mean 13.6
Standard deviation 2.2
Values 13 16 14 11
[99]
ref_hepatocyte ROCK1
Mean 6.73
Standard deviation 4.9
Values 9.7 14 3.6 2.5 3.9
[100]
HepG2 ROCK1
Mean 7.68
Standard deviation 2.4
Values 6 9.4
[101]
HepG2.C3A ROCK1
Mean 19.7
Standard deviation 1.6
Values 19 21
[102]
HuH.7 ROCK1
Mean 32.3
Standard deviation 9
Values 36 39 22
[103]
SNU475 ROCK1
Mean 31.8
Standard deviation 1.6
Values 31 33
[104]
THLE ROCK1
Mean 22.6
Standard deviation 6.2
Values 27 18
[105]
liver ROCK1
Mean 28.7
Standard deviation 3.4
Values 30 32 25 27
[106]
ref_hepatocyte DBN1
Mean 6.29
Standard deviation 6.3
Values 12 14 4.2 0.15 1.2
[107]
HepG2 DBN1
Mean 75.2
Standard deviation 18
Values 88 62
[108]
HepG2.C3A DBN1
Mean 32.7
Standard deviation 3.5
Values 35 30
[109]
HuH.7 DBN1
Mean 59.7
Standard deviation 22
Values 74 35 70
[110]
SNU475 DBN1
Mean 58.8
Standard deviation 2.4
Values 60 57
[111]
THLE DBN1
Mean 51.6
Standard deviation 3
Values 49 54
[112]
liver DBN1
Mean 1.67
Standard deviation 0.58
Values 2 0.96 2.3 1.5
[113]
ref_hepatocyte CUL3
Mean 5.91
Standard deviation 1.6
Values 7.2 7.4 3.5 5.4 6
[114]
HepG2 CUL3
Mean 20
Standard deviation 5.9
Values 16 24
[115]
HepG2.C3A CUL3
Mean 33.5
Standard deviation 2.3
Values 32 35
[116]
HuH.7 CUL3
Mean 26.4
Standard deviation 3
Values 29 23 27
[117]
SNU475 CUL3
Mean 29.9
Standard deviation 0.9
Values 29 31
[118]
THLE CUL3
Mean 35.6
Standard deviation 0.55
Values 35 36
[119]
liver CUL3
Mean 16.1
Standard deviation 5.2
Values 15 20 9.1 20
[120]
ref_hepatocyte ROCK2
Mean 5.22
Standard deviation 4.8
Values 11 9.5 3.5 0.65 1.3
[121]
HepG2 ROCK2
Mean 32
Standard deviation 6.2
Values 28 36
[122]
HepG2.C3A ROCK2
Mean 67.4
Standard deviation 23
Values 51 84
[123]
HuH.7 ROCK2
Mean 22.4
Standard deviation 6.9
Values 28 24 15
[124]
SNU475 ROCK2
Mean 59.5
Standard deviation 0.12
Values 59 60
[125]
THLE ROCK2
Mean 14.2
Standard deviation 4.3
Values 17 11
[126]
liver ROCK2
Mean 28.1
Standard deviation 15
Values 20 42 12 39
[127]
ref_hepatocyte RBBP6
Mean 5.08
Standard deviation 1.8
Values 7.3 3.8 6.9 4.3 3.2
[128]
HepG2 RBBP6
Mean 17.7
Standard deviation 4.4
Values 15 21
[129]
HepG2.C3A RBBP6
Mean 31.8
Standard deviation 3.8
Values 29 35
[130]
HuH.7 RBBP6
Mean 20.5
Standard deviation 1
Values 20 22 19
[131]
SNU475 RBBP6
Mean 17.3
Standard deviation 0.37
Values 18 17
[132]
THLE RBBP6
Mean 25.5
Standard deviation 5.8
Values 30 21
[133]
liver RBBP6
Mean 15.4
Standard deviation 2.6
Values 15 16 12 18
[134]
ref_hepatocyte MYO6
Mean 4.14
Standard deviation 2.1
Values 5.9 6.2 4.6 1.5 2.5
[135]
HepG2 MYO6
Mean 12.8
Standard deviation 1.3
Values 12 14
[136]
HepG2.C3A MYO6
Mean 25
Standard deviation 2.5
Values 27 23
[137]
HuH.7 MYO6
Mean 28.9
Standard deviation 4.2
Values 29 33 24
[138]
SNU475 MYO6
Mean 16.6
Standard deviation 3.3
Values 19 14
[139]
THLE MYO6
Mean 16.2
Standard deviation 2.4
Values 18 15
[140]
liver MYO6
Mean 28.4
Standard deviation 9.3
Values 41 26 29 18
[141]
ref_hepatocyte RHOBTB1
Mean 2.58
Standard deviation 4.4
Values 10 1.6 0.32 0.31 0.24
[142]
HepG2 RHOBTB1
Mean 40.6
Standard deviation 17
Values 29 53
[143]
HepG2.C3A RHOBTB1
Mean 30.2
Standard deviation 4.4
Values 27 33
[144]
HuH.7 RHOBTB1
Mean 11.4
Standard deviation 2.1
Values 10 14 10
[145]
SNU475 RHOBTB1
Mean 9.46
Standard deviation 1.7
Values 11 8.3
[146]
THLE RHOBTB1
Mean 4.76
Standard deviation 0.33
Values 4.5 5
[147]
liver RHOBTB1
Mean 6.68
Standard deviation 2.6
Values 6.2 6.7 3.7 10
[148]
ref_hepatocyte SPEN
Mean 1.68
Standard deviation 0.84
Values 1.4 1 3.2 1.3 1.5
[149]
HepG2 SPEN
Mean 27.3
Standard deviation 5.7
Values 23 31
[150]
HepG2.C3A SPEN
Mean 39.4
Standard deviation 1.1
Values 40 39
[151]
HuH.7 SPEN
Mean 34.3
Standard deviation 11
Values 46 34 23
[152]
SNU475 SPEN
Mean 36
Standard deviation 7.3
Values 31 41
[153]
THLE SPEN
Mean 40.1
Standard deviation 1.4
Values 39 41
[154]
liver SPEN
Mean 29.7
Standard deviation 10
Values 25 36 18 40
[155]
ref_hepatocyte PDE5A
Mean 0.272
Standard deviation 0.28
Values 0.087 0.77 0.15 0.15 0.2
[156]
HepG2 PDE5A
Mean 0.557
Standard deviation 0.27
Values 0.37 0.75
[157]
HepG2.C3A PDE5A
Mean 1.22
Standard deviation 0.49
Values 0.87 1.6
[158]
HuH.7 PDE5A
Mean 4.06
Standard deviation 1.4
Values 3.4 5.7 3.1
[159]
SNU475 PDE5A
Mean 7.63
Standard deviation 6
Values 12 3.4
[160]
THLE PDE5A
Mean 2.59
Standard deviation 0.16
Values 2.5 2.7
[161]
liver PDE5A
Mean 3.05
Standard deviation 1.4
Values 2.2 4.1 1.6 4.3