REACTOME_ASSEMBLY_OF_ACTIVE_LPL_AND_LIPC_LIPASE_COMPLEXES Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 APOC2 Apolipoprotein C-II [1] [2] [3] [4] [5] [6] [7]
2 CREB3L3 Cyclic AMP-responsive element-binding protein 3-like protein 3 [8] -2.16[9] 0.27[10] 1.34[11] -5.15[12] -4.66[13] 0.96[14]
3 ANGPTL3 Angiopoietin-related protein 3 [15] -7.66[16] -3.27[17] 0.76[18] -7.42[19] -7.90[20] 1.26[21]
4 APOA5 Apolipoprotein A-V [22] 0.36[23] 2.59[24] 0.02[25] -7.53[26] -7.05[27] 3.26[28]
5 LIPC Hepatic triacylglycerol lipase [29] 0.83[30] 1.47[31] 3.04[32] -4.66[33] -6.01[34] 0.77[35]
6 FURIN Furin [36] 4.64[37] 1.41[38] 3.14[39] 3.46[40] 3.12[41] 2.74[42]
7 APOA4 Apolipoprotein A-IV [43] 0.36[44] 2.63[45] -3.79[46] -7.95[47] -10.19[48] 2.38[49]
8 PCSK6 Proprotein convertase subtilisin/kexin type 6 [50] 3.29[51] 3.65[52] 2.52[53] -2.06[54] -3.19[55] 3.54[56]
9 ANGPTL4 Angiopoietin-related protein 4 [57] 1.30[58] 0.85[59] 0.88[60] 1.77[61] 4.93[62] 1.56[63]
10 MBTPS1 Membrane-bound transcription factor site-1 protease [64] 4.60[65] 4.93[66] 4.50[67] 6.12[68] 5.37[69] 2.40[70]
11 FGF21 Fibroblast growth factor 21 [71] -5.70[72] -7.18[73] -3.99[74] -4.53[75] -5.80[76] -1.13[77]
12 LMF2 Lipase maturation factor 2 [78] 3.88[79] 4.02[80] 4.31[81] 4.58[82] 4.31[83] 1.38[84]
13 CIDEC Cell death activator CIDE-3 [85] 1.70[86] 4.94[87] 2.44[88] -1.08[89] -2.25[90] -1.64[91]
14 MBTPS2 Membrane-bound transcription factor site-2 protease [92] 3.96[93] 4.83[94] 5.20[95] 6.82[96] 5.93[97] 2.64[98]
15 LMF1 Lipase maturation factor 1 [99] 2.14[100] 2.78[101] 3.51[102] 0.53[103] 0.79[104] 2.03[105]
16 PCSK5 Proprotein convertase subtilisin/kexin type 5 [106] 2.68[107] 0.04[108] 5.91[109] 5.39[110] 6.20[111] 2.33[112]
17 LPL Lipoprotein lipase [113] [114] [115] -4.30[116] 5.30[117] 0.86[118] 0.85[119]
18 GPIHBP1 Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 [120] 1.25[121] [122] 1.47[123] 0.70[124] 6.25[125]
19 ANGPTL8 Angiopoietin-like protein 8 [126] [127] [128] [129] [130] [131] [132]
[1]
ref_hepatocyte APOC2
Mean 1.46e+03
Standard deviation 1.8e+03
Values 32 31 4.8e+02 3.2e+03 3.6e+03
[2]
HepG2 APOC2
Missing
[3]
HepG2.C3A APOC2
Missing
[4]
HuH.7 APOC2
Missing
[5]
SNU475 APOC2
Missing
[6]
THLE APOC2
Missing
[7]
liver APOC2
Missing
[8]
ref_hepatocyte CREB3L3
Mean 95.6
Standard deviation 1.4e+02
Values 18 3.4 22 3.3e+02 1e+02
[9]
HepG2 CREB3L3
Mean 5.86
Standard deviation 3.9
Values 3.1 8.6
[10]
HepG2.C3A CREB3L3
Mean 19.5
Standard deviation 4.2
Values 22 17
[11]
HuH.7 CREB3L3
Mean 53.2
Standard deviation 6.3
Values 54 59 46
[12]
SNU475 CREB3L3
Mean 0.187
Standard deviation 0.16
Values 0.074 0.3
[13]
THLE CREB3L3
Mean 0.511
Standard deviation 0.13
Values 0.42 0.6
[14]
liver CREB3L3
Mean 125
Standard deviation 65
Values 1.1e+02 87 2.2e+02 81
[15]
ref_hepatocyte ANGPTL3
Mean 90.5
Standard deviation 1.2e+02
Values 0.88 33 5.8 1.5e+02 2.7e+02
[16]
HepG2 ANGPTL3
Mean 0.122
Standard deviation 0.076
Values 0.069 0.18
[17]
HepG2.C3A ANGPTL3
Mean 1.59
Standard deviation 0.21
Values 1.7 1.4
[18]
HuH.7 ANGPTL3
Mean 33.7
Standard deviation 10
Values 29 45 27
[19]
SNU475 ANGPTL3
Mean 0.0367
Standard deviation 0.013
Values 0.028 0.046
[20]
THLE ANGPTL3
Mean 0.0512
Standard deviation 0.02
Values 0.065 0.037
[21]
liver ANGPTL3
Mean 145
Standard deviation 86
Values 2.4e+02 1e+02 2e+02 48
[22]
ref_hepatocyte APOA5
Mean 59
Standard deviation 65
Values 27 0.62 14 1.5e+02 1e+02
[23]
HepG2 APOA5
Mean 20.8
Standard deviation 0.15
Values 21 21
[24]
HepG2.C3A APOA5
Mean 60.4
Standard deviation 19
Values 74 47
[25]
HuH.7 APOA5
Mean 13.1
Standard deviation 8.4
Values 7 23 9.7
[26]
SNU475 APOA5
Mean 0.0222
Standard deviation 0.012
Values 0.014 0.03
[27]
THLE APOA5
Mean 0.0603
Standard deviation 0.04
Values 0.089 0.032
[28]
liver APOA5
Mean 379
Standard deviation 1.6e+02
Values 3.7e+02 2.1e+02 5.9e+02 3.5e+02
[29]
ref_hepatocyte LIPC
Mean 37.4
Standard deviation 43
Values 16 9.2 4 52 1.1e+02
[30]
HepG2 LIPC
Mean 18.2
Standard deviation 4
Values 15 21
[31]
HepG2.C3A LIPC
Mean 17.6
Standard deviation 9.2
Values 24 11
[32]
HuH.7 LIPC
Mean 67.2
Standard deviation 17
Values 55 86 61
[33]
SNU475 LIPC
Mean 0.103
Standard deviation 0.027
Values 0.083 0.12
[34]
THLE LIPC
Mean 0.0784
Standard deviation 0.002
Values 0.077 0.08
[35]
liver LIPC
Mean 42.7
Standard deviation 5.7
Values 40 44 50 36
[36]
ref_hepatocyte FURIN
Mean 36.4
Standard deviation 35
Values 1.6 11 25 83 62
[37]
HepG2 FURIN
Mean 249
Standard deviation 93
Values 3.1e+02 1.8e+02
[38]
HepG2.C3A FURIN
Mean 16.4
Standard deviation 4.8
Values 13 20
[39]
HuH.7 FURIN
Mean 70.6
Standard deviation 9.9
Values 82 63 67
[40]
SNU475 FURIN
Mean 27.8
Standard deviation 0.065
Values 28 28
[41]
THLE FURIN
Mean 42.8
Standard deviation 10
Values 35 50
[42]
liver FURIN
Mean 163
Standard deviation 30
Values 2e+02 1.5e+02 1.3e+02 1.7e+02
[43]
ref_hepatocyte APOA4
Mean 25.6
Standard deviation 28
Values 11 5.3 28 74 8.8
[44]
HepG2 APOA4
Mean 9
Standard deviation 5.6
Values 13 5
[45]
HepG2.C3A APOA4
Mean 27
Standard deviation 5.6
Values 31 23
[46]
HuH.7 APOA4
Mean 0.405
Standard deviation 0.074
Values 0.33 0.47 0.41
[47]
SNU475 APOA4
Mean 0.00717
Standard deviation 0.003
Values 0.0093 0.0051
[48]
THLE APOA4
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[49]
liver APOA4
Mean 89
Standard deviation 1.1e+02
Values 2.5e+02 21 39 44
[50]
ref_hepatocyte PCSK6
Mean 25.1
Standard deviation 28
Values 6.6 3.8 3.7 55 57
[51]
HepG2 PCSK6
Mean 67.5
Standard deviation 1.1
Values 67 68
[52]
HepG2.C3A PCSK6
Mean 53.6
Standard deviation 1.4
Values 55 53
[53]
HuH.7 PCSK6
Mean 31.5
Standard deviation 2.8
Values 33 34 28
[54]
SNU475 PCSK6
Mean 0.419
Standard deviation 0.0045
Values 0.42 0.42
[55]
THLE PCSK6
Mean 0.372
Standard deviation 0.22
Values 0.53 0.22
[56]
liver PCSK6
Mean 196
Standard deviation 58
Values 1.8e+02 2.4e+02 1.2e+02 2.4e+02
[57]
ref_hepatocyte ANGPTL4
Mean 22.3
Standard deviation 19
Values 1.4 33 13 50 13
[58]
HepG2 ANGPTL4
Mean 15
Standard deviation 9.4
Values 22 8.3
[59]
HepG2.C3A ANGPTL4
Mean 6.83
Standard deviation 4.3
Values 9.9 3.8
[60]
HuH.7 ANGPTL4
Mean 9.01
Standard deviation 1.7
Values 7.9 11 8.2
[61]
SNU475 ANGPTL4
Mean 5.26
Standard deviation 6
Values 0.99 9.5
[62]
THLE ANGPTL4
Mean 92.2
Standard deviation 13
Values 1e+02 83
[63]
liver ANGPTL4
Mean 44
Standard deviation 33
Values 21 18 90 47
[64]
ref_hepatocyte MBTPS1
Mean 12.1
Standard deviation 4.1
Values 19 13 9.9 9.7 9
[65]
HepG2 MBTPS1
Mean 80.3
Standard deviation 2.9
Values 82 78
[66]
HepG2.C3A MBTPS1
Mean 62.7
Standard deviation 9.8
Values 70 56
[67]
HuH.7 MBTPS1
Mean 59.9
Standard deviation 6.7
Values 65 53 62
[68]
SNU475 MBTPS1
Mean 58.2
Standard deviation 23
Values 75 42
[69]
THLE MBTPS1
Mean 67.8
Standard deviation 8.7
Values 62 74
[70]
liver MBTPS1
Mean 42.8
Standard deviation 5.9
Values 34 46 46 45
[71]
ref_hepatocyte FGF21
Mean 8.3
Standard deviation 14
Values 0 0.13 7.9 33 0.55
[72]
HepG2 FGF21
Mean 0.0437
Standard deviation 0.044
Values 0.074 0.013
[73]
HepG2.C3A FGF21
Mean 0.00972
Standard deviation 0.014
Values 0.019 0
[74]
HuH.7 FGF21
Mean 0.114
Standard deviation 0.084
Values 0.066 0.21 0.066
[75]
SNU475 FGF21
Mean 0.0249
Standard deviation 0.022
Values 0.0093 0.041
[76]
THLE FGF21
Mean 0.0201
Standard deviation 0.013
Values 0.03 0.011
[77]
liver FGF21
Mean 2.54
Standard deviation 3.1
Values 7.2 0.9 1.2 0.87
[78]
ref_hepatocyte LMF2
Mean 8.29
Standard deviation 5.7
Values 3.6 2.2 7.4 15 14
[79]
HepG2 LMF2
Mean 33.4
Standard deviation 0.42
Values 34 33
[80]
HepG2.C3A LMF2
Mean 22.9
Standard deviation 6.4
Values 27 18
[81]
HuH.7 LMF2
Mean 36.1
Standard deviation 5
Values 41 31 37
[82]
SNU475 LMF2
Mean 13.8
Standard deviation 0.61
Values 14 13
[83]
THLE LMF2
Mean 22.2
Standard deviation 3.3
Values 20 25
[84]
liver LMF2
Mean 14.5
Standard deviation 5.6
Values 18 8.7 20 11
[85]
ref_hepatocyte CIDEC
Mean 2.94
Standard deviation 1.2
Values 3.7 4.2 3.4 1.7 1.8
[86]
HepG2 CIDEC
Mean 2.61
Standard deviation 0.13
Values 2.5 2.7
[87]
HepG2.C3A CIDEC
Mean 15.3
Standard deviation 4.7
Values 19 12
[88]
HuH.7 CIDEC
Mean 3.51
Standard deviation 1.2
Values 3.5 2.3 4.7
[89]
SNU475 CIDEC
Mean 0.0965
Standard deviation 0.064
Values 0.051 0.14
[90]
THLE CIDEC
Mean 0.0837
Standard deviation 0.0096
Values 0.077 0.09
[91]
liver CIDEC
Mean 0.632
Standard deviation 1
Values 0.094 0.17 2.2 0.079
[92]
ref_hepatocyte MBTPS2
Mean 2.91
Standard deviation 1.1
Values 4.3 3.5 1.3 2.3 3.2
[93]
HepG2 MBTPS2
Mean 12.4
Standard deviation 2.3
Values 11 14
[94]
HepG2.C3A MBTPS2
Mean 14.1
Standard deviation 0.19
Values 14 14
[95]
HuH.7 MBTPS2
Mean 23.4
Standard deviation 5.3
Values 25 27 17
[96]
SNU475 MBTPS2
Mean 22.8
Standard deviation 3.1
Values 25 21
[97]
THLE MBTPS2
Mean 23.9
Standard deviation 2.4
Values 22 26
[98]
liver MBTPS2
Mean 12.1
Standard deviation 2.3
Values 11 12 15 9.9
[99]
ref_hepatocyte LMF1
Mean 2.34
Standard deviation 1.9
Values 0.63 1.5 0.7 4.3 4.6
[100]
HepG2 LMF1
Mean 2.83
Standard deviation 1
Values 3.5 2.1
[101]
HepG2.C3A LMF1
Mean 2.72
Standard deviation 2.3
Values 4.4 1.1
[102]
HuH.7 LMF1
Mean 5.84
Standard deviation 1.1
Values 7.1 5.4 5
[103]
SNU475 LMF1
Mean 0.234
Standard deviation 0.19
Values 0.37 0.1
[104]
THLE LMF1
Mean 0.547
Standard deviation 0.089
Values 0.61 0.48
[105]
liver LMF1
Mean 6.38
Standard deviation 2.5
Values 9.7 3.6 6.8 5.4
[106]
ref_hepatocyte PCSK5
Mean 0.477
Standard deviation 0.61
Values 0.42 1.5 0.35 0.052 0.033
[107]
HepG2 PCSK5
Mean 0.841
Standard deviation 0.42
Values 0.54 1.1
[108]
HepG2.C3A PCSK5
Mean 0.0833
Standard deviation 0.049
Values 0.049 0.12
[109]
HuH.7 PCSK5
Mean 6.3
Standard deviation 1.6
Values 7 7.5 4.5
[110]
SNU475 PCSK5
Mean 1.38
Standard deviation 0.11
Values 1.3 1.5
[111]
THLE PCSK5
Mean 4.75
Standard deviation 0.93
Values 4.1 5.4
[112]
liver PCSK5
Mean 1.6
Standard deviation 1.2
Values 0.73 2.2 0.49 3
[113]
ref_hepatocyte LPL
Mean 0.193
Standard deviation 0.37
Values 0 0.065 0.86 0.043 0
[114]
HepG2 LPL
Mean 0
Standard deviation 0
Values 0 0
[115]
HepG2.C3A LPL
Mean 0
Standard deviation 0
Values 0 0
[116]
HuH.7 LPL
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[117]
SNU475 LPL
Mean 0.525
Standard deviation 0.3
Values 0.31 0.74
[118]
THLE LPL
Mean 0.0473
Standard deviation 0.0083
Values 0.041 0.053
[119]
liver LPL
Mean 0.233
Standard deviation 0.16
Values 0.28 0.057 0.15 0.44
[120]
ref_hepatocyte GPIHBP1
Mean 0.0121
Standard deviation 0.027
Values 0 0 0 0.06 0
[121]
HepG2 GPIHBP1
Mean 0
Standard deviation 0
Values 0 0
[122]
HepG2.C3A GPIHBP1
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[123]
HuH.7 GPIHBP1
Mean 0
Standard deviation 0
Values 0 0 0
[124]
SNU475 GPIHBP1
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[125]
THLE GPIHBP1
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[126]
liver GPIHBP1
Mean 0.614
Standard deviation 0.21
Values 0.92 0.6 0.44 0.5
[127]
ref_hepatocyte ANGPTL8
Missing
[128]
HepG2 ANGPTL8
Missing
[129]
HepG2.C3A ANGPTL8
Missing
[130]
HuH.7 ANGPTL8
Missing
[131]
SNU475 ANGPTL8
Missing
[132]
THLE ANGPTL8
Missing
[133]
liver ANGPTL8
Missing