REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CLTA Clathrin light chain A [1] -2.06[2] -2.02[3] -2.40[4] -2.77[5] -2.58[6] -3.35[7]
2 AP2M1 AP-2 complex subunit mu [8] 0.04[9] 0.05[10] -0.93[11] 0.67[12] 1.00[13] -0.25[14]
3 AP2S1 AP-2 complex subunit sigma [15] -1.80[16] -1.61[17] -1.39[18] -1.05[19] -0.80[20] -1.11[21]
4 CLTC Clathrin heavy chain 1 [22] 1.44[23] 1.75[24] 1.44[25] 1.37[26] 1.33[27] 2.37[28]
5 DNM2 Dynamin-2 [29] 1.83[30] 0.98[31] 0.76[32] 0.65[33] 0.73[34] 0.69[35]
6 AP2A1 AP-2 complex subunit alpha-1 [36] 1.03[37] 0.90[38] 1.25[39] 1.10[40] 0.98[41] 0.87[42]
7 AP2B1 AP-2 complex subunit beta [43] 2.06[44] 2.00[45] 3.24[46] 2.25[47] 1.92[48] 0.85[49]
8 AP2A2 AP-2 complex subunit alpha-2 [50] 1.08[51] 1.14[52] 0.78[53] 0.54[54] 0.00[55] 0.59[56]
9 DNAL4 Dynein light chain 4, axonemal [57] -0.28[58] -0.07[59] -0.41[60] -1.72[61] -1.30[62] -1.44[63]
10 DNM1 Dynamin-1 [64] 2.06[65] 0.45[66] 1.66[67] 5.29[68] 4.59[69] 1.85[70]
11 SH3GL2 Endophilin-A1 [71] -2.43[72] [73] -5.50[74] 0.71[75] -0.71[76] 0.10[77]
12 DNM3 Dynamin-3 [78] -1.05[79] 0.35[80] 3.55[81] 8.27[82] 3.97[83] 5.27[84]
13 NTRK1 High affinity nerve growth factor receptor [85] [86] [87] [88] [89] [90] [91]
14 NGF Beta-nerve growth factor [92] [93] [94] [95] [96] [97] [98]
[1]
ref_hepatocyte CLTA
Mean 139
Standard deviation 77
Values 2e+02 2.3e+02 1.4e+02 74 53
[2]
HepG2 CLTA
Mean 83.5
Standard deviation 9.9
Values 91 77
[3]
HepG2.C3A CLTA
Mean 65.7
Standard deviation 0.97
Values 66 65
[4]
HuH.7 CLTA
Mean 68.1
Standard deviation 8
Values 60 68 76
[5]
SNU475 CLTA
Mean 46.3
Standard deviation 2.6
Values 48 45
[6]
THLE CLTA
Mean 67.1
Standard deviation 17
Values 55 79
[7]
liver CLTA
Mean 20.5
Standard deviation 13
Values 32 10 31 8.4
[8]
ref_hepatocyte AP2M1
Mean 41.6
Standard deviation 13
Values 28 39 35 63 44
[9]
HepG2 AP2M1
Mean 107
Standard deviation 14
Values 97 1.2e+02
[10]
HepG2.C3A AP2M1
Mean 83
Standard deviation 17
Values 71 95
[11]
HuH.7 AP2M1
Mean 56.4
Standard deviation 14
Values 67 40 62
[12]
SNU475 AP2M1
Mean 150
Standard deviation 32
Values 1.7e+02 1.3e+02
[13]
THLE AP2M1
Mean 241
Standard deviation 26
Values 2.2e+02 2.6e+02
[14]
liver AP2M1
Mean 52.8
Standard deviation 26
Values 55 35 89 32
[15]
ref_hepatocyte AP2S1
Mean 38.3
Standard deviation 23
Values 13 36 20 57 66
[16]
HepG2 AP2S1
Mean 27.5
Standard deviation 0.19
Values 28 27
[17]
HepG2.C3A AP2S1
Mean 24.1
Standard deviation 3.4
Values 22 27
[18]
HuH.7 AP2S1
Mean 37.6
Standard deviation 15
Values 43 21 49
[19]
SNU475 AP2S1
Mean 42
Standard deviation 3.1
Values 44 40
[20]
THLE AP2S1
Mean 63.5
Standard deviation 6.7
Values 59 68
[21]
liver AP2S1
Mean 26.7
Standard deviation 27
Values 53 3.8 46 3.4
[22]
ref_hepatocyte CLTC
Mean 30
Standard deviation 17
Values 53 42 13 19 24
[23]
HepG2 CLTC
Mean 203
Standard deviation 93
Values 1.4e+02 2.7e+02
[24]
HepG2.C3A CLTC
Mean 193
Standard deviation 28
Values 1.7e+02 2.1e+02
[25]
HuH.7 CLTC
Mean 209
Standard deviation 37
Values 2.5e+02 2.1e+02 1.7e+02
[26]
SNU475 CLTC
Mean 176
Standard deviation 18
Values 1.9e+02 1.6e+02
[27]
THLE CLTC
Mean 218
Standard deviation 18
Values 2.1e+02 2.3e+02
[28]
liver CLTC
Mean 234
Standard deviation 1.1e+02
Values 1.2e+02 3.7e+02 1.8e+02 2.7e+02
[29]
ref_hepatocyte DNM2
Mean 12.4
Standard deviation 3.9
Values 7.7 11 17 16 11
[30]
HepG2 DNM2
Mean 111
Standard deviation 21
Values 1.3e+02 96
[31]
HepG2.C3A DNM2
Mean 47.1
Standard deviation 1.8
Values 48 46
[32]
HuH.7 DNM2
Mean 54.4
Standard deviation 4.5
Values 59 53 51
[33]
SNU475 DNM2
Mean 44.3
Standard deviation 3.3
Values 47 42
[34]
THLE DNM2
Mean 59.7
Standard deviation 7.8
Values 54 65
[35]
liver DNM2
Mean 30.1
Standard deviation 7.9
Values 23 30 26 41
[36]
ref_hepatocyte AP2A1
Mean 10.6
Standard deviation 3.7
Values 6.9 8.6 9.7 17 11
[37]
HepG2 AP2A1
Mean 54
Standard deviation 4.5
Values 57 51
[38]
HepG2.C3A AP2A1
Mean 38.1
Standard deviation 9.3
Values 45 32
[39]
HuH.7 AP2A1
Mean 65.1
Standard deviation 18
Values 85 50 60
[40]
SNU475 AP2A1
Mean 51.3
Standard deviation 9.3
Values 58 45
[41]
THLE AP2A1
Mean 60.6
Standard deviation 7.6
Values 55 66
[42]
liver AP2A1
Mean 29.1
Standard deviation 3.1
Values 28 27 27 34
[43]
ref_hepatocyte AP2B1
Mean 9
Standard deviation 4.1
Values 11 15 5.6 5.9 7.2
[44]
HepG2 AP2B1
Mean 93.9
Standard deviation 10
Values 87 1e+02
[45]
HepG2.C3A AP2B1
Mean 69.3
Standard deviation 14
Values 79 59
[46]
HuH.7 AP2B1
Mean 220
Standard deviation 43
Values 2.7e+02 2e+02 1.9e+02
[47]
SNU475 AP2B1
Mean 96.9
Standard deviation 32
Values 1.2e+02 74
[48]
THLE AP2B1
Mean 98.4
Standard deviation 18
Values 86 1.1e+02
[49]
liver AP2B1
Mean 24.4
Standard deviation 6.6
Values 18 34 23 23
[50]
ref_hepatocyte AP2A2
Mean 8.24
Standard deviation 1.1
Values 7.8 6.8 8.3 9.9 8.3
[51]
HepG2 AP2A2
Mean 43.6
Standard deviation 9.6
Values 50 37
[52]
HepG2.C3A AP2A2
Mean 34.8
Standard deviation 12
Values 43 26
[53]
HuH.7 AP2A2
Mean 36.5
Standard deviation 2.7
Values 39 36 34
[54]
SNU475 AP2A2
Mean 27.1
Standard deviation 8.1
Values 33 21
[55]
THLE AP2A2
Mean 23.9
Standard deviation 4.3
Values 21 27
[56]
liver AP2A2
Mean 18.6
Standard deviation 3.8
Values 21 19 13 22
[57]
ref_hepatocyte DNAL4
Mean 3.21
Standard deviation 1
Values 3.3 1.7 2.8 4.4 3.8
[58]
HepG2 DNAL4
Mean 6.61
Standard deviation 0.7
Values 7.1 6.1
[59]
HepG2.C3A DNAL4
Mean 5.89
Standard deviation 0.5
Values 6.2 5.5
[60]
HuH.7 DNAL4
Mean 6.22
Standard deviation 0.77
Values 5.8 5.7 7.1
[61]
SNU475 DNAL4
Mean 2.21
Standard deviation 0.6
Values 2.6 1.8
[62]
THLE DNAL4
Mean 3.79
Standard deviation 0.51
Values 3.4 4.1
[63]
liver DNAL4
Mean 1.78
Standard deviation 0.92
Values 2.9 1 2.1 1.1
[64]
ref_hepatocyte DNM1
Mean 0.16
Standard deviation 0.16
Values 0 0.15 0 0.35 0.3
[65]
HepG2 DNM1
Mean 1.67
Standard deviation 1.2
Values 2.5 0.85
[66]
HepG2.C3A DNM1
Mean 0.418
Standard deviation 0.29
Values 0.62 0.21
[67]
HuH.7 DNM1
Mean 1.31
Standard deviation 0.22
Values 1.3 1.5 1.1
[68]
SNU475 DNM1
Mean 14.2
Standard deviation 4.2
Values 17 11
[69]
THLE DNM1
Mean 11.2
Standard deviation 0.44
Values 11 11
[70]
liver DNM1
Mean 0.869
Standard deviation 0.9
Values 0.73 0.36 0.21 2.2
[71]
ref_hepatocyte SH3GL2
Mean 0.0479
Standard deviation 0.06
Values 0 0.041 0 0.052 0.15
[72]
HepG2 SH3GL2
Mean 0.0222
Standard deviation 0.023
Values 0.0057 0.039
[73]
HepG2.C3A SH3GL2
Mean 0
Standard deviation 0
Values 0 0
[74]
HuH.7 SH3GL2
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[75]
SNU475 SH3GL2
Mean 0.178
Standard deviation 0.19
Values 0.046 0.31
[76]
THLE SH3GL2
Mean 0.0849
Standard deviation 0.022
Values 0.1 0.069
[77]
liver SH3GL2
Mean 0.0774
Standard deviation 0.058
Values 0.047 0.014 0.1 0.15
[78]
ref_hepatocyte DNM3
Mean 0.0154
Standard deviation 0.026
Values 0 0.06 0 0.017 0
[79]
HepG2 DNM3
Mean 0.0186
Standard deviation 0.01
Values 0.011 0.026
[80]
HepG2.C3A DNM3
Mean 0.0375
Standard deviation 0.053
Values 0 0.075
[81]
HuH.7 DNM3
Mean 0.465
Standard deviation 0.2
Values 0.34 0.69 0.37
[82]
SNU475 DNM3
Mean 10.7
Standard deviation 2.7
Values 13 8.8
[83]
THLE DNM3
Mean 0.697
Standard deviation 0.015
Values 0.69 0.71
[84]
liver DNM3
Mean 0.891
Standard deviation 0.52
Values 0.96 1.2 0.13 1.3
[85]
ref_hepatocyte NTRK1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[86]
HepG2 NTRK1
Mean 0.0172
Standard deviation 0.024
Values 0.034 0
[87]
HepG2.C3A NTRK1
Mean 0
Standard deviation 0
Values 0 0
[88]
HuH.7 NTRK1
Mean 0
Standard deviation 0
Values 0 0 0
[89]
SNU475 NTRK1
Mean 0.439
Standard deviation 0.25
Values 0.26 0.62
[90]
THLE NTRK1
Mean 0.0556
Standard deviation 0.012
Values 0.047 0.064
[91]
liver NTRK1
Mean 0.0711
Standard deviation 0.026
Values 0.071 0.071 0.1 0.04
[92]
ref_hepatocyte NGF
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[93]
HepG2 NGF
Mean 0
Standard deviation 0
Values 0 0
[94]
HepG2.C3A NGF
Mean 0
Standard deviation 0
Values 0 0
[95]
HuH.7 NGF
Mean 0
Standard deviation 0
Values 0 0 0
[96]
SNU475 NGF
Mean 1.32
Standard deviation 0.58
Values 0.91 1.7
[97]
THLE NGF
Mean 0.258
Standard deviation 0.011
Values 0.27 0.25
[98]
liver NGF
Mean 0.426
Standard deviation 0.42
Values 1 0.071 0.46 0.16