REACTOME_RETINOID_CYCLE_DISEASE_EVENTS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 RBP4 Retinol-binding protein 4 [1] 0.07[2] 0.12[3] 0.51[4] -4.64[5] -1.63[6] 0.37[7]
2 TTR Transthyretin [8] -1.47[9] -0.29[10] -1.76[11] -7.41[12] -4.61[13] -0.90[14]
3 RDH5 11-cis retinol dehydrogenase [15] -2.15[16] -1.32[17] -1.65[18] -0.18[19] 2.84[20] -1.32[21]
4 RBP1 Retinol-binding protein 1 [22] 7.78[23] 1.93[24] 2.87[25] 7.11[26] 5.80[27] 2.34[28]
5 NAPEPLD N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D [29] 5.21[30] 5.11[31] 5.68[32] 9.19[33] 10.04[34] 3.55[35]
6 RDH12 Retinol dehydrogenase 12 [36] 4.42[37] 5.43[38] -1.69[39] 3.69[40] 6.50[41] 1.84[42]
7 LRAT Lecithin retinol acyltransferase [43] 3.94[44] 3.38[45] 1.82[46] 6.86[47] 9.96[48] 6.69[49]
8 ABCA4 Retinal-specific ATP-binding cassette transporter [50] 9.56[51] 4.63[52] 5.80[53] 11.28[54] 9.18[55] 4.95[56]
9 STRA6 Receptor for retinol uptake STRA6 [57] 11.55[58] 6.37[59] 2.55[60] 16.58[61] 15.45[62] -1.48[63]
10 RLBP1 Retinaldehyde-binding protein 1 [64] [65] [66] [67] [68] [69] [70]
11 OPN1MW Medium-wave-sensitive opsin 1 [71] [72] [73] [74] [75] [76] [77]
12 OPN1SW Short-wave-sensitive opsin 1 [78] [79] [80] [81] [82] [83] [84]
13 OPN1LW Long-wave-sensitive opsin 1 [85] [86] [87] [88] [89] [90] [91]
[1]
ref_hepatocyte RBP4
Mean 3.15e+03
Standard deviation 4.2e+03
Values 2.4e+02 2.1e+02 6e+02 5e+03 9.7e+03
[2]
HepG2 RBP4
Mean 147
Standard deviation 7.2
Values 1.5e+02 1.4e+02
[3]
HepG2.C3A RBP4
Mean 297
Standard deviation 52
Values 3.3e+02 2.6e+02
[4]
HuH.7 RBP4
Mean 472
Standard deviation 54
Values 4.9e+02 4.1e+02 5.2e+02
[5]
SNU475 RBP4
Mean 0.74
Standard deviation 0.5
Values 0.38 1.1
[6]
THLE RBP4
Mean 1.18
Standard deviation 0.52
Values 1.5 0.81
[7]
liver RBP4
Mean 2.05e+03
Standard deviation 1.9e+03
Values 4.2e+03 4.1e+02 3.1e+03 4.9e+02
[8]
ref_hepatocyte TTR
Mean 2.04e+03
Standard deviation 3.1e+03
Values 80 1.8e+02 2.9e+02 2.5e+03 7.2e+03
[9]
HepG2 TTR
Mean 32.6
Standard deviation 28
Values 13 53
[10]
HepG2.C3A TTR
Mean 145
Standard deviation 36
Values 1.7e+02 1.2e+02
[11]
HuH.7 TTR
Mean 63.5
Standard deviation 11
Values 60 55 76
[12]
SNU475 TTR
Mean 0.0705
Standard deviation 0.0079
Values 0.065 0.076
[13]
THLE TTR
Mean 0.097
Standard deviation 0.047
Values 0.13 0.064
[14]
liver TTR
Mean 555
Standard deviation 6.9e+02
Values 1.5e+03 59 6e+02 53
[15]
ref_hepatocyte RDH5
Mean 23.8
Standard deviation 26
Values 0.53 17 3.6 35 64
[16]
HepG2 RDH5
Mean 0.238
Standard deviation 0.045
Values 0.27 0.21
[17]
HepG2.C3A RDH5
Mean 0.829
Standard deviation 0.051
Values 0.87 0.79
[18]
HuH.7 RDH5
Mean 0.802
Standard deviation 0.21
Values 0.58 0.99 0.83
[19]
SNU475 RDH5
Mean 0.123
Standard deviation 0.023
Values 0.14 0.11
[20]
THLE RDH5
Mean 0.198
Standard deviation 0.021
Values 0.18 0.21
[21]
liver RDH5
Mean 4.84
Standard deviation 3.7
Values 4.5 4 9.8 1.1
[22]
ref_hepatocyte RBP1
Mean 4.21
Standard deviation 1.7
Values 6.5 5.6 3.2 3.4 2.4
[23]
HepG2 RBP1
Mean 41.1
Standard deviation 6.5
Values 46 36
[24]
HepG2.C3A RBP1
Mean 1.39
Standard deviation 0.9
Values 0.76 2
[25]
HuH.7 RBP1
Mean 3.24
Standard deviation 1.6
Values 3.7 1.4 4.6
[26]
SNU475 RBP1
Mean 3.41
Standard deviation 1.4
Values 4.4 2.4
[27]
THLE RBP1
Mean 0.272
Standard deviation 0.092
Values 0.34 0.21
[28]
liver RBP1
Mean 10.8
Standard deviation 10
Values 24 2 14 3.6
[29]
ref_hepatocyte NAPEPLD
Mean 1.95
Standard deviation 1.3
Values 1.1 2.6 0.44 1.7 3.8
[30]
HepG2 NAPEPLD
Mean 3.18
Standard deviation 1.3
Values 2.3 4.1
[31]
HepG2.C3A NAPEPLD
Mean 5.82
Standard deviation 0.86
Values 5.2 6.4
[32]
HuH.7 NAPEPLD
Mean 10.5
Standard deviation 0.91
Values 11 9.6 11
[33]
SNU475 NAPEPLD
Mean 6.63
Standard deviation 0.69
Values 7.1 6.1
[34]
THLE NAPEPLD
Mean 2.38
Standard deviation 0.027
Values 2.4 2.4
[35]
liver NAPEPLD
Mean 11.6
Standard deviation 3.7
Values 17 11 8.2 11
[36]
ref_hepatocyte RDH12
Mean 0.661
Standard deviation 0.71
Values 0.31 0.065 0.22 1.8 0.9
[37]
HepG2 RDH12
Mean 0.626
Standard deviation 0.27
Values 0.82 0.43
[38]
HepG2.C3A RDH12
Mean 2.47
Standard deviation 0.33
Values 2.7 2.2
[39]
HuH.7 RDH12
Mean 0.0216
Standard deviation 0.015
Values 0.0082 0.019 0.037
[40]
SNU475 RDH12
Mean 0.05
Standard deviation 0.051
Values 0.014 0.086
[41]
THLE RDH12
Mean 0.0692
Standard deviation 0.023
Values 0.053 0.085
[42]
liver RDH12
Mean 1.2
Standard deviation 1.2
Values 0.63 1 2.9 0.19
[43]
ref_hepatocyte LRAT
Mean 0.0892
Standard deviation 0.057
Values 0.14 0.12 0.052 0.12 0.0081
[44]
HepG2 LRAT
Mean 0.0608
Standard deviation 0.005
Values 0.057 0.064
[45]
HepG2.C3A LRAT
Mean 0.0803
Standard deviation 0.038
Values 0.11 0.054
[46]
HuH.7 LRAT
Mean 0.0332
Standard deviation 0.029
Values 0.0082 0.026 0.066
[47]
SNU475 LRAT
Mean 0.0606
Standard deviation 0.00038
Values 0.06 0.061
[48]
THLE LRAT
Mean 0.103
Standard deviation 0.055
Values 0.14 0.064
[49]
liver LRAT
Mean 4.65
Standard deviation 3.2
Values 9.2 2.5 4.5 2.4
[50]
ref_hepatocyte ABCA4
Mean 0.0577
Standard deviation 0.042
Values 0.096 0.065 0 0.095 0.033
[51]
HepG2 ABCA4
Mean 1.94
Standard deviation 0.43
Values 2.2 1.6
[52]
HepG2.C3A ABCA4
Mean 0.124
Standard deviation 0.11
Values 0.2 0.043
[53]
HuH.7 ABCA4
Mean 0.338
Standard deviation 0.27
Values 0.19 0.65 0.18
[54]
SNU475 ABCA4
Mean 0.839
Standard deviation 0.51
Values 0.48 1.2
[55]
THLE ABCA4
Mean 0.0387
Standard deviation 0.013
Values 0.03 0.048
[56]
liver ABCA4
Mean 0.9
Standard deviation 0.48
Values 0.47 1.2 0.51 1.4
[57]
ref_hepatocyte STRA6
Mean 0.0325
Standard deviation 0.055
Values 0.13 0 0.035 0 0
[58]
HepG2 STRA6
Mean 4.33
Standard deviation 0.93
Values 5 3.7
[59]
HepG2.C3A STRA6
Mean 0.233
Standard deviation 0.056
Values 0.27 0.19
[60]
HuH.7 STRA6
Mean 0.0201
Standard deviation 0.021
Values 0.041 0.019 0
[61]
SNU475 STRA6
Mean 18.6
Standard deviation 10
Values 11 26
[62]
THLE STRA6
Mean 1.68
Standard deviation 0.51
Values 2 1.3
[63]
liver STRA6
Mean 0.00588
Standard deviation 0.012
Values 0.024 0 0 0
[64]
ref_hepatocyte RLBP1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[65]
HepG2 RLBP1
Mean 0.519
Standard deviation 0.35
Values 0.77 0.27
[66]
HepG2.C3A RLBP1
Mean 0.0603
Standard deviation 0.025
Values 0.078 0.043
[67]
HuH.7 RLBP1
Mean 0.00487
Standard deviation 0.0043
Values 0.0082 0.0064 0
[68]
SNU475 RLBP1
Mean 0.0076
Standard deviation 0.011
Values 0 0.015
[69]
THLE RLBP1
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[70]
liver RLBP1
Mean 0.038
Standard deviation 0.031
Values 0.071 0.029 0 0.053
[71]
ref_hepatocyte OPN1MW
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[72]
HepG2 OPN1MW
Missing
[73]
HepG2.C3A OPN1MW
Missing
[74]
HuH.7 OPN1MW
Missing
[75]
SNU475 OPN1MW
Missing
[76]
THLE OPN1MW
Missing
[77]
liver OPN1MW
Missing
[78]
ref_hepatocyte OPN1SW
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[79]
HepG2 OPN1SW
Mean 0.0215
Standard deviation 0.018
Values 0.034 0.0086
[80]
HepG2.C3A OPN1SW
Mean 0.0769
Standard deviation 0.013
Values 0.068 0.086
[81]
HuH.7 OPN1SW
Mean 0.102
Standard deviation 0.048
Values 0.12 0.13 0.047
[82]
SNU475 OPN1SW
Mean 0.0331
Standard deviation 0.025
Values 0.051 0.015
[83]
THLE OPN1SW
Mean 0.0384
Standard deviation 0.021
Values 0.024 0.053
[84]
liver OPN1SW
Mean 0.0333
Standard deviation 0.058
Values 0 0.014 0 0.12
[85]
ref_hepatocyte OPN1LW
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[86]
HepG2 OPN1LW
Missing
[87]
HepG2.C3A OPN1LW
Missing
[88]
HuH.7 OPN1LW
Missing
[89]
SNU475 OPN1LW
Missing
[90]
THLE OPN1LW
Missing
[91]
liver OPN1LW
Missing