REACTOME_RESPONSE_OF_MTB_TO_PHAGOCYTOSIS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 UBB Polyubiquitin-B [1] -1.63[2] -1.90[3] -1.48[4] -2.06[5] -1.27[6] -0.49[7]
2 RPS27A Ubiquitin-40S ribosomal protein S27a [8] [9] [10] [11] [12] [13] [14]
3 UBC Polyubiquitin-C [15] -1.19[16] -1.15[17] -1.11[18] -1.21[19] -0.89[20] -0.04[21]
4 ENO1 Alpha-enolase [22] 1.28[23] 1.67[24] 1.10[25] 1.36[26] 0.94[27] 0.03[28]
5 PGK1 Phosphoglycerate kinase 1 [29] 1.93[30] 1.00[31] 1.12[32] 2.10[33] 1.77[34] 1.14[35]
6 RAB7A Ras-related protein Rab-7a [36] -0.23[37] -0.82[38] -0.35[39] -0.35[40] 0.51[41] 0.07[42]
7 SFPQ Splicing factor, proline- and glutamine-rich [43] 0.23[44] -0.04[45] 0.57[46] 0.34[47] 0.61[48] 0.32[49]
8 UBA52 Ubiquitin-60S ribosomal protein L40 [50] 1.25[51] 1.09[52] 2.40[53] 0.19[54] 1.33[55] 0.73[56]
9 KPNB1 Importin subunit beta-1 [57] 1.49[58] 1.57[59] 2.13[60] 1.91[61] 1.85[62] 0.84[63]
10 TRIM27 Zinc finger protein RFP [64] 1.29[65] 1.17[66] 0.59[67] 0.61[68] 0.52[69] 1.68[70]
11 HGS Hepatocyte growth factor-regulated tyrosine kinase substrate [71] 1.47[72] 0.90[73] 0.65[74] 1.21[75] 1.46[76] 0.61[77]
12 RAB5A Ras-related protein Rab-5A [78] -0.30[79] -0.20[80] 1.10[81] 0.48[82] 1.18[83] 1.20[84]
13 MAPK1 Mitogen-activated protein kinase 1 [85] 2.28[86] 2.35[87] 2.44[88] 2.57[89] 2.55[90] 3.16[91]
14 ATP6V1H V-type proton ATPase subunit H [92] 0.25[93] 0.07[94] -0.50[95] 1.34[96] 1.57[97] 0.83[98]
15 GSK3A Glycogen synthase kinase-3 alpha [99] 1.19[100] 0.86[101] 1.23[102] 0.80[103] 1.89[104] -0.45[105]
16 DUSP16 Dual specificity protein phosphatase 16 [106] 2.14[107] 2.08[108] 2.09[109] -0.68[110] 0.55[111] 2.83[112]
17 KPNA1 Importin subunit alpha-5 [113] 1.62[114] 1.61[115] 1.98[116] 2.30[117] 2.94[118] 3.56[119]
18 MAPK3 Mitogen-activated protein kinase 3 [120] 2.42[121] 2.39[122] 2.71[123] 1.14[124] 1.49[125] 0.34[126]
19 RNF213 E3 ubiquitin-protein ligase RNF213 [127] 4.57[128] 2.80[129] 4.89[130] 5.07[131] 4.49[132] 6.47[133]
20 VPS33B Vacuolar protein sorting-associated protein 33B [134] 0.84[135] 0.87[136] 1.48[137] 1.16[138] 1.32[139] 1.02[140]
21 CORO1A Coronin-1A [141] 1.13[142] 0.64[143] -0.46[144] -1.81[145] -0.77[146] 1.56[147]
22 NOS2 Nitric oxide synthase, inducible [148] 0.59[149] [150] -5.45[151] -4.14[152] -4.70[153] -5.93[154]
23 CTSG Cathepsin G [155] [156] [157] [158] [159] [160] -0.78[161]
[1]
ref_hepatocyte UBB
Mean 764
Standard deviation 4.8e+02
Values 3.8e+02 3.5e+02 5.3e+02 1.2e+03 1.3e+03
[2]
HepG2 UBB
Mean 368
Standard deviation 39
Values 4e+02 3.4e+02
[3]
HepG2.C3A UBB
Mean 285
Standard deviation 14
Values 2.8e+02 3e+02
[4]
HuH.7 UBB
Mean 304
Standard deviation 40
Values 2.9e+02 2.7e+02 3.5e+02
[5]
SNU475 UBB
Mean 204
Standard deviation 3.3
Values 2.1e+02 2e+02
[6]
THLE UBB
Mean 315
Standard deviation 34
Values 2.9e+02 3.4e+02
[7]
liver UBB
Mean 296
Standard deviation 1.3e+02
Values 4.3e+02 2.1e+02 3.9e+02 1.5e+02
[8]
ref_hepatocyte RPS27A
Mean 499
Standard deviation 2.2e+02
Values 6.6e+02 6.1e+02 1.7e+02 6.8e+02 3.8e+02
[9]
HepG2 RPS27A
Missing
[10]
HepG2.C3A RPS27A
Missing
[11]
HuH.7 RPS27A
Missing
[12]
SNU475 RPS27A
Missing
[13]
THLE RPS27A
Missing
[14]
liver RPS27A
Missing
[15]
ref_hepatocyte UBC
Mean 480
Standard deviation 2.8e+02
Values 1.8e+02 3.5e+02 9.1e+02 5.8e+02 3.8e+02
[16]
HepG2 UBC
Mean 314
Standard deviation 38
Values 3.4e+02 2.9e+02
[17]
HepG2.C3A UBC
Mean 302
Standard deviation 41
Values 3.3e+02 2.7e+02
[18]
HuH.7 UBC
Mean 246
Standard deviation 64
Values 2.4e+02 3.1e+02 1.9e+02
[19]
SNU475 UBC
Mean 232
Standard deviation 63
Values 2.8e+02 1.9e+02
[20]
THLE UBC
Mean 257
Standard deviation 41
Values 2.3e+02 2.9e+02
[21]
liver UBC
Mean 254
Standard deviation 78
Values 2.2e+02 3.1e+02 3.3e+02 1.6e+02
[22]
ref_hepatocyte ENO1
Mean 440
Standard deviation 3.1e+02
Values 3.8e+02 9.6e+02 3.8e+02 3.3e+02 1.5e+02
[23]
HepG2 ENO1
Mean 1.59e+03
Standard deviation 4.1e+02
Values 1.9e+03 1.3e+03
[24]
HepG2.C3A ENO1
Mean 1.95e+03
Standard deviation 1.1e+02
Values 1.9e+03 2e+03
[25]
HuH.7 ENO1
Mean 1.04e+03
Standard deviation 1.2e+02
Values 1.2e+03 9.6e+02 9.9e+02
[26]
SNU475 ENO1
Mean 1.26e+03
Standard deviation 1.1e+02
Values 1.3e+03 1.2e+03
[27]
THLE ENO1
Mean 842
Standard deviation 1.1e+02
Values 7.6e+02 9.2e+02
[28]
liver ENO1
Mean 244
Standard deviation 1.2e+02
Values 2.9e+02 1.8e+02 3.8e+02 1.2e+02
[29]
ref_hepatocyte PGK1
Mean 96.6
Standard deviation 45
Values 93 1.7e+02 57 94 67
[30]
HepG2 PGK1
Mean 546
Standard deviation 1e+02
Values 6.2e+02 4.7e+02
[31]
HepG2.C3A PGK1
Mean 269
Standard deviation 62
Values 2.3e+02 3.1e+02
[32]
HuH.7 PGK1
Mean 233
Standard deviation 56
Values 2.2e+02 1.8e+02 2.9e+02
[33]
SNU475 PGK1
Mean 461
Standard deviation 5.7
Values 4.7e+02 4.6e+02
[34]
THLE PGK1
Mean 327
Standard deviation 5
Values 3.2e+02 3.3e+02
[35]
liver PGK1
Mean 116
Standard deviation 43
Values 1.1e+02 1.1e+02 1.7e+02 68
[36]
ref_hepatocyte RAB7A
Mean 94.8
Standard deviation 33
Values 83 1.4e+02 1.2e+02 63 69
[37]
HepG2 RAB7A
Mean 120
Standard deviation 5.7
Values 1.2e+02 1.2e+02
[38]
HepG2.C3A RAB7A
Mean 74.7
Standard deviation 5.5
Values 71 79
[39]
HuH.7 RAB7A
Mean 82.4
Standard deviation 5.2
Values 84 77 87
[40]
SNU475 RAB7A
Mean 83
Standard deviation 9.2
Values 90 77
[41]
THLE RAB7A
Mean 135
Standard deviation 27
Values 1.2e+02 1.5e+02
[42]
liver RAB7A
Mean 54.3
Standard deviation 44
Values 90 18 95 14
[43]
ref_hepatocyte SFPQ
Mean 58.6
Standard deviation 45
Values 1.3e+02 80 47 21 19
[44]
HepG2 SFPQ
Mean 103
Standard deviation 18
Values 90 1.2e+02
[45]
HepG2.C3A SFPQ
Mean 79.6
Standard deviation 17
Values 68 91
[46]
HuH.7 SFPQ
Mean 96.1
Standard deviation 21
Values 1e+02 73 1.1e+02
[47]
SNU475 SFPQ
Mean 83
Standard deviation 12
Values 92 74
[48]
THLE SFPQ
Mean 89.2
Standard deviation 28
Values 69 1.1e+02
[49]
liver SFPQ
Mean 39.7
Standard deviation 28
Values 13 62 18 65
[50]
ref_hepatocyte UBA52
Mean 57.3
Standard deviation 43
Values 14 23 49 1.2e+02 81
[51]
HepG2 UBA52
Mean 203
Standard deviation 20
Values 2.2e+02 1.9e+02
[52]
HepG2.C3A UBA52
Mean 169
Standard deviation 3.3
Values 1.7e+02 1.7e+02
[53]
HuH.7 UBA52
Mean 334
Standard deviation 46
Values 3.4e+02 2.8e+02 3.7e+02
[54]
SNU475 UBA52
Mean 72.9
Standard deviation 11
Values 65 81
[55]
THLE UBA52
Mean 144
Standard deviation 15
Values 1.3e+02 1.5e+02
[56]
liver UBA52
Mean 51.7
Standard deviation 26
Values 79 32 68 28
[57]
ref_hepatocyte KPNB1
Mean 41.8
Standard deviation 31
Values 59 85 38 12 15
[58]
HepG2 KPNB1
Mean 174
Standard deviation 21
Values 1.6e+02 1.9e+02
[59]
HepG2.C3A KPNB1
Mean 173
Standard deviation 25
Values 1.5e+02 1.9e+02
[60]
HuH.7 KPNB1
Mean 203
Standard deviation 28
Values 2.4e+02 1.9e+02 1.8e+02
[61]
SNU475 KPNB1
Mean 176
Standard deviation 10
Values 1.7e+02 1.8e+02
[62]
THLE KPNB1
Mean 150
Standard deviation 26
Values 1.3e+02 1.7e+02
[63]
liver KPNB1
Mean 40.6
Standard deviation 13
Values 32 58 29 44
[64]
ref_hepatocyte TRIM27
Mean 17.7
Standard deviation 5.4
Values 16 16 27 17 13
[65]
HepG2 TRIM27
Mean 64.5
Standard deviation 5.8
Values 69 60
[66]
HepG2.C3A TRIM27
Mean 55.2
Standard deviation 9.4
Values 62 49
[67]
HuH.7 TRIM27
Mean 29.4
Standard deviation 4
Values 31 25 32
[68]
SNU475 TRIM27
Mean 30.1
Standard deviation 1
Values 31 29
[69]
THLE TRIM27
Mean 25.2
Standard deviation 3.4
Values 23 28
[70]
liver TRIM27
Mean 30.7
Standard deviation 6.3
Values 23 33 38 30
[71]
ref_hepatocyte HGS
Mean 16.6
Standard deviation 15
Values 6.9 15 42 11 8.1
[72]
HepG2 HGS
Mean 68.4
Standard deviation 17
Values 80 57
[73]
HepG2.C3A HGS
Mean 43.2
Standard deviation 8
Values 49 38
[74]
HuH.7 HGS
Mean 28.9
Standard deviation 4.1
Values 30 24 32
[75]
SNU475 HGS
Mean 43.1
Standard deviation 3.7
Values 40 46
[76]
THLE HGS
Mean 45.7
Standard deviation 2.6
Values 44 48
[77]
liver HGS
Mean 13.8
Standard deviation 3.3
Values 17 9.3 16 14
[78]
ref_hepatocyte RAB5A
Mean 12.8
Standard deviation 4.6
Values 9.3 19 16 8.8 10
[79]
HepG2 RAB5A
Mean 15.4
Standard deviation 2.7
Values 13 17
[80]
HepG2.C3A RAB5A
Mean 15.5
Standard deviation 1.2
Values 16 15
[81]
HuH.7 RAB5A
Mean 30.3
Standard deviation 3.3
Values 30 34 27
[82]
SNU475 RAB5A
Mean 19.8
Standard deviation 0.012
Values 20 20
[83]
THLE RAB5A
Mean 28.9
Standard deviation 0.86
Values 28 29
[84]
liver RAB5A
Mean 15.9
Standard deviation 6.4
Values 22 11 21 9.6
[85]
ref_hepatocyte MAPK1
Mean 10.7
Standard deviation 3.7
Values 14 13 13 6.1 7.4
[86]
HepG2 MAPK1
Mean 77.6
Standard deviation 22
Values 62 93
[87]
HepG2.C3A MAPK1
Mean 76.1
Standard deviation 7.2
Values 71 81
[88]
HuH.7 MAPK1
Mean 64.8
Standard deviation 7.4
Values 73 60 61
[89]
SNU475 MAPK1
Mean 71.1
Standard deviation 8
Values 77 65
[90]
THLE MAPK1
Mean 62.4
Standard deviation 14
Values 53 72
[91]
liver MAPK1
Mean 52.3
Standard deviation 14
Values 39 68 41 61
[92]
ref_hepatocyte ATP6V1H
Mean 9.45
Standard deviation 4.2
Values 11 16 9 6 5.4
[93]
HepG2 ATP6V1H
Mean 16.7
Standard deviation 1.6
Values 16 18
[94]
HepG2.C3A ATP6V1H
Mean 13.8
Standard deviation 1.4
Values 15 13
[95]
HuH.7 ATP6V1H
Mean 7.42
Standard deviation 1.1
Values 6.7 8.7 6.9
[96]
SNU475 ATP6V1H
Mean 26.7
Standard deviation 6.6
Values 31 22
[97]
THLE ATP6V1H
Mean 27.9
Standard deviation 4.7
Values 25 31
[98]
liver ATP6V1H
Mean 9.12
Standard deviation 3.6
Values 13 6.6 11 5.6
[99]
ref_hepatocyte GSK3A
Mean 9.38
Standard deviation 5.1
Values 7.5 3.9 17 12 6.4
[100]
HepG2 GSK3A
Mean 31.9
Standard deviation 3.3
Values 34 30
[101]
HepG2.C3A GSK3A
Mean 23.7
Standard deviation 0.26
Values 24 24
[102]
HuH.7 GSK3A
Mean 24.3
Standard deviation 3.3
Values 26 21 26
[103]
SNU475 GSK3A
Mean 18.2
Standard deviation 1.9
Values 17 20
[104]
THLE GSK3A
Mean 34.6
Standard deviation 4.3
Values 32 38
[105]
liver GSK3A
Mean 3.74
Standard deviation 0.84
Values 4.7 3.1 3 4.2
[106]
ref_hepatocyte DUSP16
Mean 7.61
Standard deviation 4
Values 4.7 12 12 6.1 3.5
[107]
HepG2 DUSP16
Mean 49.8
Standard deviation 0.41
Values 50 50
[108]
HepG2.C3A DUSP16
Mean 44.8
Standard deviation 6.7
Values 50 40
[109]
HuH.7 DUSP16
Mean 35.9
Standard deviation 14
Values 33 51 24
[110]
SNU475 DUSP16
Mean 5.29
Standard deviation 0.16
Values 5.4 5.2
[111]
THLE DUSP16
Mean 11.1
Standard deviation 0.034
Values 11 11
[112]
liver DUSP16
Mean 29.5
Standard deviation 18
Values 14 47 14 43
[113]
ref_hepatocyte KPNA1
Mean 5.92
Standard deviation 2.1
Values 4.8 9.6 4.9 4.9 5.3
[114]
HepG2 KPNA1
Mean 27.1
Standard deviation 7
Values 22 32
[115]
HepG2.C3A KPNA1
Mean 25.1
Standard deviation 1.6
Values 24 26
[116]
HuH.7 KPNA1
Mean 25.8
Standard deviation 2.3
Values 28 25 24
[117]
SNU475 KPNA1
Mean 32.6
Standard deviation 0.51
Values 32 33
[118]
THLE KPNA1
Mean 45.2
Standard deviation 4
Values 42 48
[119]
liver KPNA1
Mean 38
Standard deviation 4.3
Values 40 36 43 33
[120]
ref_hepatocyte MAPK3
Mean 4.16
Standard deviation 1.3
Values 5.1 2.8 3.6 6 3.3
[121]
HepG2 MAPK3
Mean 33.1
Standard deviation 5.2
Values 37 29
[122]
HepG2.C3A MAPK3
Mean 30.4
Standard deviation 12
Values 39 22
[123]
HuH.7 MAPK3
Mean 30
Standard deviation 4.8
Values 34 25 32
[124]
SNU475 MAPK3
Mean 10.2
Standard deviation 2.4
Values 12 8.5
[125]
THLE MAPK3
Mean 11.6
Standard deviation 1.1
Values 11 12
[126]
liver MAPK3
Mean 2.87
Standard deviation 2.4
Values 5 0.81 4.8 0.82
[127]
ref_hepatocyte RNF213
Mean 2.84
Standard deviation 1.5
Values 5.1 3.4 1.9 1.6 2.2
[128]
HepG2 RNF213
Mean 100
Standard deviation 19
Values 1.1e+02 87
[129]
HepG2.C3A RNF213
Mean 27.4
Standard deviation 3.6
Values 30 25
[130]
HuH.7 RNF213
Mean 93
Standard deviation 34
Values 1.1e+02 1.1e+02 54
[131]
SNU475 RNF213
Mean 106
Standard deviation 43
Values 1.4e+02 76
[132]
THLE RNF213
Mean 63.4
Standard deviation 5.5
Values 60 67
[133]
liver RNF213
Mean 137
Standard deviation 89
Values 69 2.1e+02 50 2.2e+02
[134]
ref_hepatocyte VPS33B
Mean 2.56
Standard deviation 0.54
Values 2.8 2.4 3.2 2.6 1.8
[135]
HepG2 VPS33B
Mean 6.81
Standard deviation 0.25
Values 7 6.6
[136]
HepG2.C3A VPS33B
Mean 6.52
Standard deviation 0.48
Values 6.2 6.9
[137]
HuH.7 VPS33B
Mean 7.9
Standard deviation 0.9
Values 8.5 6.9 8.4
[138]
SNU475 VPS33B
Mean 6.39
Standard deviation 0.43
Values 6.7 6.1
[139]
THLE VPS33B
Mean 6.38
Standard deviation 0.032
Values 6.4 6.4
[140]
liver VPS33B
Mean 2.82
Standard deviation 0.31
Values 3.2 2.7 2.5 2.9
[141]
ref_hepatocyte CORO1A
Mean 2.37
Standard deviation 3.2
Values 0.13 0 0.92 3.1 7.7
[142]
HepG2 CORO1A
Mean 7.69
Standard deviation 2.9
Values 9.8 5.6
[143]
HepG2.C3A CORO1A
Mean 5.13
Standard deviation 0.49
Values 4.8 5.5
[144]
HuH.7 CORO1A
Mean 1.91
Standard deviation 0.67
Values 2 1.2 2.5
[145]
SNU475 CORO1A
Mean 0.756
Standard deviation 0.23
Values 0.59 0.92
[146]
THLE CORO1A
Mean 1.39
Standard deviation 0.24
Values 1.2 1.6
[147]
liver CORO1A
Mean 3.8
Standard deviation 1.3
Values 4.5 2.3 5.2 3.2
[148]
ref_hepatocyte NOS2
Mean 0.74
Standard deviation 1.6
Values 0 0 3.7 0 0.024
[149]
HepG2 NOS2
Mean 1.66
Standard deviation 0.53
Values 1.3 2
[150]
HepG2.C3A NOS2
Mean 0
Standard deviation 0
Values 0 0
[151]
HuH.7 NOS2
Mean 0.0187
Standard deviation 0.017
Values 0.0082 0.039 0.0094
[152]
SNU475 NOS2
Mean 0.0469
Standard deviation 0.027
Values 0.028 0.066
[153]
THLE NOS2
Mean 0.0284
Standard deviation 0.01
Values 0.035 0.021
[154]
liver NOS2
Mean 0.00662
Standard deviation 0.013
Values 0 0 0 0.026
[155]
ref_hepatocyte CTSG
Mean 0.731
Standard deviation 1.1
Values 0 0 0 1.2 2.4
[156]
HepG2 CTSG
Mean 0
Standard deviation 0
Values 0 0
[157]
HepG2.C3A CTSG
Mean 0
Standard deviation 0
Values 0 0
[158]
HuH.7 CTSG
Mean 0
Standard deviation 0
Values 0 0 0
[159]
SNU475 CTSG
Mean 0
Standard deviation 0
Values 0 0
[160]
THLE CTSG
Mean 0
Standard deviation 0
Values 0 0
[161]
liver CTSG
Mean 0.232
Standard deviation 0.29
Values 0.071 0.21 0.64 0