REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | RPS27 | 40S ribosomal protein S27 | [1] | [2] | [3] | [4] | [5] | [6] | [7] |
2 | TUBA1B | Tubulin alpha-1B chain | [8] | -0.35[9] | -0.58[10] | -0.42[11] | -0.70[12] | -0.26[13] | -1.39[14] |
3 | TUBA1C | Tubulin alpha-1C chain | [15] | -0.96[16] | -1.28[17] | -1.86[18] | -1.36[19] | -1.85[20] | -2.62[21] |
4 | TUBB4B | Tubulin beta-4B chain | [22] | -0.30[23] | -0.64[24] | -0.74[25] | -1.39[26] | -0.62[27] | -0.30[28] |
5 | DYNLL1 | Dynein light chain 1, cytoplasmic | [29] | -0.89[30] | -1.09[31] | -1.39[32] | -1.37[33] | -1.76[34] | -0.95[35] |
6 | NUDC | Nuclear migration protein nudC | [36] | -0.44[37] | -1.17[38] | -1.37[39] | -1.69[40] | -1.81[41] | -1.33[42] |
7 | TUBA4A | Tubulin alpha-4A chain | [43] | -3.56[44] | -3.96[45] | -4.81[46] | -1.55[47] | -1.83[48] | -1.46[49] |
8 | TUBB2A | Tubulin beta-2A chain | [50] | -2.74[51] | -3.08[52] | -1.89[53] | -1.88[54] | -4.26[55] | -1.62[56] |
9 | SEC13 | Protein SEC13 homolog | [57] | -0.46[58] | -0.33[59] | -0.22[60] | -1.48[61] | -1.44[62] | -0.40[63] |
10 | DYNLL2 | Dynein light chain 2, cytoplasmic | [64] | -0.47[65] | -1.27[66] | -1.12[67] | -2.62[68] | -1.15[69] | -1.78[70] |
11 | PPP2R1A | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isofor | 1.29[71] | 0.88[72] | 0.72[73] | 1.46[74] | 0.67[75] | 1.30[76] | |
12 | PPP2CA | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform | 0.76[77] | 0.62[78] | -0.10[79] | 0.99[80] | 0.99[81] | 1.05[82] | |
13 | PPP1CC | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit | 1.17[83] | 1.72[84] | 1.86[85] | 0.49[86] | 0.48[87] | 0.08[88] | |
14 | PPP2CB | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform | 0.10[89] | -0.48[90] | -0.48[91] | -0.20[92] | -0.43[93] | 0.17[94] | |
15 | RANGAP1 | Ran GTPase-activating protein 1 | [95] | 1.14[96] | 0.60[97] | 0.37[98] | -0.12[99] | 0.62[100] | 0.18[101] |
16 | MAPRE1 | Microtubule-associated protein RP/EB family member 1 | [102] | 2.16[103] | 1.52[104] | 0.78[105] | 1.94[106] | 1.05[107] | -0.39[108] |
17 | BUB3 | Mitotic checkpoint protein BUB3 | [109] | 0.80[110] | 1.45[111] | 0.75[112] | -0.05[113] | 1.28[114] | 0.56[115] |
18 | RAD21 | Double-strand-break repair protein rad21 homolog | [116] | 0.93[117] | 2.08[118] | 2.09[119] | 2.31[120] | 1.82[121] | 1.53[122] |
19 | PMF1 | Polyamine-modulated factor 1 | [123] | -1.86[124] | -1.66[125] | -2.08[126] | -1.79[127] | -2.29[128] | -0.40[129] |
20 | DYNC1I2 | Cytoplasmic dynein 1 intermediate chain 2 | [130] | 0.91[131] | 1.14[132] | 0.85[133] | 1.05[134] | 0.59[135] | 0.58[136] |
21 | DYNC1LI2 | Cytoplasmic dynein 1 light intermediate chain 2 | [137] | 1.04[138] | 1.04[139] | 0.47[140] | 1.41[141] | 1.56[142] | 1.49[143] |
22 | PPP2R5A | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform | -0.63[144] | 0.02[145] | 0.66[146] | 0.00[147] | -1.24[148] | 1.79[149] | |
23 | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isofor | 0.18[150] | 0.82[151] | 0.44[152] | 1.19[153] | 0.88[154] | 0.96[155] | |
24 | XPO1 | Exportin-1 | [156] | 1.85[157] | 2.32[158] | 2.27[159] | 2.38[160] | 2.35[161] | 2.02[162] |
25 | PPP2R1B | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform | 0.94[163] | 0.18[164] | 0.51[165] | 0.52[166] | 0.19[167] | 4.09[168] | |
26 | DYNC1LI1 | Cytoplasmic dynein 1 light intermediate chain 1 | [169] | -0.08[170] | -0.07[171] | 0.85[172] | -0.50[173] | 0.02[174] | 0.14[175] |
27 | NDEL1 | Nuclear distribution protein nudE-like 1 | [176] | 0.15[177] | 0.60[178] | -0.52[179] | -0.32[180] | -0.37[181] | 0.75[182] |
28 | TUBB3 | Tubulin beta-3 chain | [183] | 2.85[184] | 1.55[185] | -2.69[186] | 1.28[187] | -1.95[188] | -6.61[189] |
29 | SMC3 | Structural maintenance of chromosomes protein 3 | [190] | -0.68[191] | 1.74[192] | 2.12[193] | 0.67[194] | 0.97[195] | 1.21[196] |
30 | SPC25 | Kinetochore protein Spc25 | [197] | -1.22[198] | -0.63[199] | -1.14[200] | -0.87[201] | -0.68[202] | -1.04[203] |
31 | TUBB6 | Tubulin beta-6 chain | [204] | 1.29[205] | -1.03[206] | 0.50[207] | 1.98[208] | 2.19[209] | -0.52[210] |
32 | SEH1L | Nucleoporin SEH1 | [211] | 0.72[212] | 0.97[213] | 1.34[214] | 0.82[215] | -0.07[216] | 1.34[217] |
33 | CLIP1 | CAP-Gly domain-containing linker protein 1 | [218] | -0.11[219] | 1.10[220] | 1.43[221] | 1.25[222] | 1.08[223] | 2.77[224] |
34 | PAFAH1B1 | Platelet-activating factor acetylhydrolase IB subunit alpha | [225] | 1.28[226] | 1.15[227] | 1.02[228] | 2.39[229] | 2.14[230] | 2.00[231] |
35 | DYNC1H1 | Cytoplasmic dynein 1 heavy chain 1 | [232] | 4.06[233] | 2.41[234] | 3.14[235] | 3.91[236] | 3.80[237] | 4.35[238] |
36 | MAD2L1 | Mitotic spindle assembly checkpoint protein MAD2A | [239] | 1.09[240] | 1.97[241] | 1.22[242] | 0.30[243] | 1.30[244] | -1.72[245] |
37 | CCNB1 | G2/mitotic-specific cyclin-B1 | [246] | 2.34[247] | 2.33[248] | 2.43[249] | 1.86[250] | 2.72[251] | -1.19[252] |
38 | ZWINT | ZW10 interactor | [253] | 1.42[254] | 1.90[255] | 0.82[256] | 1.65[257] | 1.75[258] | -1.09[259] |
39 | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform | 1.74[260] | 1.26[261] | 0.74[262] | 1.54[263] | 1.31[264] | 0.89[265] | |
40 | CENPT | Centromere protein T | [266] | 0.37[267] | 0.46[268] | 0.04[269] | -0.41[270] | -0.06[271] | 1.03[272] |
41 | BIRC5 | Baculoviral IAP repeat-containing protein 5 | [273] | 2.07[274] | 2.28[275] | 2.15[276] | 0.93[277] | 1.64[278] | -1.16[279] |
42 | PDS5A | Sister chromatid cohesion protein PDS5 homolog A | [280] | 1.36[281] | 2.00[282] | 2.09[283] | 1.70[284] | 2.28[285] | 3.35[286] |
43 | NUP85 | Nuclear pore complex protein Nup85 | [287] | 1.23[288] | 1.35[289] | 1.51[290] | 0.83[291] | 0.91[292] | 1.38[293] |
44 | SKA2 | Spindle and kinetochore-associated protein 2 | [294] | 0.27[295] | 1.07[296] | 1.67[297] | 0.48[298] | 1.38[299] | 0.62[300] |
45 | HDAC8 | Histone deacetylase 8 | [301] | -0.48[302] | -0.92[303] | -0.73[304] | -0.52[305] | -0.41[306] | 0.80[307] |
46 | RANBP2 | E3 SUMO-protein ligase RanBP2 | [308] | 0.97[309] | 2.41[310] | 2.07[311] | 1.79[312] | 1.82[313] | 4.11[314] |
47 | NUP98 | Nuclear pore complex protein Nup98-Nup96 | [315] | 2.66[316] | 2.11[317] | 2.29[318] | 2.48[319] | 1.92[320] | 3.01[321] |
48 | RCC2 | Protein RCC2 | [322] | 2.56[323] | 2.08[324] | 1.99[325] | 2.63[326] | 2.27[327] | 0.58[328] |
49 | TUBB2B | Tubulin beta-2B chain | [329] | 1.16[330] | -0.21[331] | -0.32[332] | -0.18[333] | -4.22[334] | -3.05[335] |
50 | NUP107 | Nuclear pore complex protein Nup107 | [336] | 0.99[337] | 1.87[338] | 1.77[339] | 1.54[340] | 1.35[341] | 1.15[342] |
51 | CDK1 | Cyclin-dependent kinase 1 | [343] | 1.74[344] | 3.57[345] | 2.22[346] | 2.52[347] | 3.22[348] | -1.31[349] |
52 | PPP2R5E | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isofor | 0.60[350] | 0.54[351] | 0.00[352] | 1.11[353] | 0.78[354] | 1.35[355] | |
53 | CKAP5 | Cytoskeleton-associated protein 5 | [356] | 2.96[357] | 2.88[358] | 3.50[359] | 2.73[360] | 2.94[361] | 2.65[362] |
54 | NUP37 | Nucleoporin Nup37 | [363] | 1.15[364] | 1.19[365] | 1.21[366] | 0.70[367] | 0.58[368] | -0.27[369] |
55 | AURKB | Aurora kinase B | [370] | 1.08[371] | 1.20[372] | 2.15[373] | 0.59[374] | 1.01[375] | -2.20[376] |
56 | STAG2 | Cohesin subunit SA-2 | [377] | 0.77[378] | 2.55[379] | 3.48[380] | 2.79[381] | 2.15[382] | 3.11[383] |
57 | MIS12 | Protein MIS12 homolog | [384] | 0.24[385] | 0.64[386] | 0.43[387] | 0.69[388] | 0.86[389] | 1.03[390] |
58 | MAD1L1 | Mitotic spindle assembly checkpoint protein MAD1 | [391] | 1.13[392] | 0.38[393] | 0.40[394] | -0.40[395] | 0.02[396] | 0.87[397] |
59 | PLK1 | Serine/threonine-protein kinase PLK1 | [398] | 2.98[399] | 2.49[400] | 2.26[401] | 1.50[402] | 2.42[403] | -1.47[404] |
60 | DSN1 | Kinetochore-associated protein DSN1 homolog | [405] | 1.28[406] | 1.32[407] | 1.47[408] | 1.52[409] | 1.42[410] | 0.21[411] |
61 | CENPN | Centromere protein N | [412] | 1.52[413] | 1.96[414] | 2.43[415] | 1.59[416] | 2.16[417] | 0.87[418] |
62 | NUP160 | Nuclear pore complex protein Nup160 | [419] | 2.35[420] | 2.26[421] | 2.78[422] | 1.43[423] | 1.61[424] | 2.63[425] |
63 | SMC1A | Structural maintenance of chromosomes protein 1A | [426] | 2.59[427] | 2.22[428] | 3.14[429] | 3.27[430] | 3.99[431] | 3.60[432] |
64 | ZW10 | Centromere/kinetochore protein zw10 homolog | [433] | 1.11[434] | 0.75[435] | 0.38[436] | 1.52[437] | 1.16[438] | 1.73[439] |
65 | NUP133 | Nuclear pore complex protein Nup133 | [440] | 1.68[441] | 1.79[442] | 2.66[443] | 2.46[444] | 1.69[445] | 2.20[446] |
66 | CDCA5 | Sororin | [447] | 2.16[448] | 1.89[449] | 1.47[450] | 1.51[451] | 2.02[452] | -1.79[453] |
67 | CDC20 | Cell division cycle protein 20 homolog | [454] | 2.85[455] | 2.63[456] | 2.92[457] | 2.76[458] | 3.29[459] | -1.15[460] |
68 | AHCTF1 | Protein ELYS | [461] | 0.95[462] | 2.09[463] | 2.32[464] | 2.47[465] | 1.66[466] | 2.90[467] |
69 | NUP43 | Nucleoporin Nup43 | [468] | 2.40[469] | 2.34[470] | 2.01[471] | 2.34[472] | 1.95[473] | 1.47[474] |
70 | ITGB3BP | Centromere protein R | [475] | -0.43[476] | 1.03[477] | 1.24[478] | -0.11[479] | 0.43[480] | -0.29[481] |
71 | TUBA1A | Tubulin alpha-1A chain | [482] | 2.66[483] | -0.96[484] | -4.24[485] | 4.34[486] | 1.74[487] | 1.16[488] |
72 | NDC80 | Kinetochore protein NDC80 homolog | [489] | 0.11[490] | 1.98[491] | 2.09[492] | 2.37[493] | 2.39[494] | -1.34[495] |
73 | SPC24 | Kinetochore protein Spc24 | [496] | -0.86[497] | -0.98[498] | -0.45[499] | -1.03[500] | -0.29[501] | -3.55[502] |
74 | STAG1 | Cohesin subunit SA-1 | [503] | 0.94[504] | 1.99[505] | 1.10[506] | 1.83[507] | 1.81[508] | 3.33[509] |
75 | KIF2A | Kinesin-like protein KIF2A | [510] | 1.33[511] | 1.48[512] | 2.22[513] | 2.59[514] | 2.18[515] | 1.70[516] |
76 | ZWILCH | Protein zwilch homolog | [517] | 1.15[518] | 2.19[519] | 3.12[520] | 1.86[521] | 2.44[522] | 0.63[523] |
77 | CLASP1 | CLIP-associating protein 1 | [524] | 3.03[525] | 2.78[526] | 2.39[527] | 2.77[528] | 2.71[529] | 4.07[530] |
78 | CENPA | Histone H3-like centromeric protein A | [531] | 1.00[532] | 1.56[533] | 0.73[534] | 0.58[535] | 1.29[536] | -3.44[537] |
79 | CDCA8 | Borealin | [538] | 2.21[539] | 2.30[540] | 2.92[541] | 2.08[542] | 2.75[543] | -1.10[544] |
80 | INCENP | Inner centromere protein | [545] | 1.95[546] | 1.48[547] | 2.55[548] | 2.40[549] | 2.69[550] | 0.39[551] |
81 | PPP2R5B | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform | 1.27[552] | 0.79[553] | 0.07[554] | 0.54[555] | 1.59[556] | 1.25[557] | |
82 | NUF2 | Kinetochore protein Nuf2 | [558] | 0.39[559] | 2.52[560] | 1.90[561] | 2.35[562] | 2.29[563] | -1.71[564] |
83 | CCNB2 | G2/mitotic-specific cyclin-B2 | [565] | 2.58[566] | 3.10[567] | 3.40[568] | 2.77[569] | 3.64[570] | -0.45[571] |
84 | CENPH | Centromere protein H | [572] | 0.66[573] | 1.64[574] | 2.82[575] | 1.46[576] | 1.42[577] | -2.14[578] |
85 | BUB1B | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta | [579] | 2.63[580] | 3.10[581] | 2.93[582] | 3.32[583] | 3.49[584] | -0.44[585] |
86 | BUB1 | Mitotic checkpoint serine/threonine-protein kinase BUB1 | [586] | 2.68[587] | 3.59[588] | 3.14[589] | 3.34[590] | 3.58[591] | -0.16[592] |
87 | TAOK1 | Serine/threonine-protein kinase TAO1 | [593] | 2.89[594] | 3.46[595] | 4.30[596] | 4.34[597] | 3.69[598] | 4.99[599] |
88 | CLASP2 | CLIP-associating protein 2 | [600] | 2.34[601] | 2.37[602] | 3.51[603] | 2.55[604] | 2.78[605] | 3.67[606] |
89 | CENPK | Centromere protein K | [607] | 0.48[608] | 2.08[609] | 2.82[610] | 1.74[611] | 2.23[612] | -1.38[613] |
90 | CENPQ | Centromere protein Q | [614] | 0.29[615] | 1.74[616] | 1.22[617] | 1.70[618] | 1.51[619] | -0.40[620] |
91 | PDS5B | Sister chromatid cohesion protein PDS5 homolog B | [621] | 1.60[622] | 2.63[623] | 2.84[624] | 2.38[625] | 2.26[626] | 3.73[627] |
92 | KIF2C | Kinesin-like protein KIF2C | [628] | 3.66[629] | 3.74[630] | 4.05[631] | 3.38[632] | 4.39[633] | -0.36[634] |
93 | NDE1 | Nuclear distribution protein nudE homolog 1 | [635] | 3.15[636] | 2.18[637] | 1.11[638] | 1.01[639] | 1.86[640] | 1.10[641] |
94 | CENPL | Centromere protein L | [642] | 0.89[643] | 0.82[644] | 1.18[645] | 2.40[646] | 2.23[647] | -0.31[648] |
95 | CENPO | Centromere protein O | [649] | 2.95[650] | 2.86[651] | 2.56[652] | 2.61[653] | 2.79[654] | 1.12[655] |
96 | NSL1 | Kinetochore-associated protein NSL1 homolog | [656] | 3.32[657] | 4.00[658] | 3.87[659] | 3.34[660] | 2.84[661] | 4.26[662] |
97 | CENPI | Centromere protein I | [663] | 0.30[664] | 0.82[665] | 2.08[666] | 2.17[667] | 1.66[668] | -1.27[669] |
98 | SKA1 | Spindle and kinetochore-associated protein 1 | [670] | 2.17[671] | 2.44[672] | 1.84[673] | 2.45[674] | 3.13[675] | 0.97[676] |
99 | B9D2 | B9 domain-containing protein 2 | [677] | -0.52[678] | -0.17[679] | -0.59[680] | -0.62[681] | -0.28[682] | 0.45[683] |
100 | TUBA8 | Tubulin alpha-8 chain | [684] | -2.94[685] | -1.86[686] | -1.30[687] | -1.80[688] | -2.54[689] | 0.43[690] |
101 | CENPF | Centromere protein F | [691] | 3.06[692] | 5.47[693] | 5.24[694] | 5.30[695] | 5.42[696] | 2.60[697] |
102 | CENPP | Centromere protein P | [698] | 0.27[699] | 0.18[700] | 0.57[701] | 0.00[702] | 0.83[703] | -0.05[704] |
103 | CENPE | Centromere-associated protein E | [705] | 1.29[706] | 4.13[707] | 3.66[708] | 2.94[709] | 4.42[710] | 1.52[711] |
104 | CENPM | Centromere protein M | [712] | 3.14[713] | 2.98[714] | 2.53[715] | 1.65[716] | 2.68[717] | 0.18[718] |
105 | DYNC1I1 | Cytoplasmic dynein 1 intermediate chain 1 | [719] | -4.17[720] | -6.91[721] | 1.31[722] | 0.90[723] | -2.50[724] | -0.19[725] |
106 | KNTC1 | Kinetochore-associated protein 1 | [726] | 3.26[727] | 4.80[728] | 5.12[729] | 4.29[730] | 4.63[731] | 3.29[732] |
107 | KIF18A | Kinesin-like protein KIF18A | [733] | 1.83[734] | 3.71[735] | 4.54[736] | 4.50[737] | 3.53[738] | 0.70[739] |
108 | ERCC6L | DNA excision repair protein ERCC-6-like | [740] | 2.61[741] | 2.76[742] | 3.47[743] | 4.04[744] | 3.98[745] | 2.49[746] |
109 | TUBB8 | Tubulin beta-8 chain | [747] | 1.06[748] | -0.22[749] | 2.16[750] | -0.57[751] | -4.56[752] | -3.57[753] |
110 | TUBA3D | [754] | -1.50[755] | -1.00[756] | -1.94[757] | -0.23[758] | -1.64[759] | 1.17[760] | |
111 | TUBB1 | Tubulin beta-1 chain | [761] | 5.07[762] | 6.68[763] | 2.43[764] | 3.05[765] | 1.60[766] | 4.71[767] |
112 | TUBB4A | Tubulin beta-4A chain | [768] | 2.31[769] | -2.04[770] | 4.41[771] | 3.88[772] | 2.33[773] | 3.00[774] |
113 | TUBA3E | Tubulin alpha-3E chain | [775] | [776] | -4.53[777] | -4.38[778] | -4.43[779] | -2.18[780] | 0.72[781] |
114 | TUBA3C | Tubulin alpha-3C/D chain | [782] | [783] | -4.01[784] | [785] | 1.44[786] | -5.06[787] | -3.08[788] |
115 | SGO1 | Shugoshin 1 | [789] | [790] | [791] | [792] | [793] | [794] | [795] |
116 | TUBA4B | Putative tubulin-like protein alpha-4B | [796] | [797] | [798] | [799] | [800] | [801] | [802] |
117 | CENPS | Centromere protein S | [803] | [804] | [805] | [806] | [807] | [808] | [809] |
118 | TUBAL3 | Tubulin alpha chain-like 3 | [810] | [811] | [812] | [813] | [814] | [815] | [816] |
119 | KIF2B | Kinesin-like protein KIF2B | [817] | [818] | [819] | [820] | [821] | [822] | [823] |
120 | SPDL1 | Protein Spindly | [824] | [825] | [826] | [827] | [828] | [829] | [830] |
121 | TUBB8B | [831] | [832] | [833] | [834] | [835] | [836] | [837] | |
122 | SGO2 | Shugoshin 2 | [838] | [839] | [840] | [841] | [842] | [843] | [844] |
123 | KNL1 | Kinetochore scaffold 1 | [845] | [846] | [847] | [848] | [849] | [850] | [851] |
124 | WAPL | Wings apart-like protein homolog | [852] | [853] | [854] | [855] | [856] | [857] | [858] |
125 | CENPU | Centromere protein U | [859] | [860] | [861] | [862] | [863] | [864] | [865] |
126 | CENPC | Centromere protein C | [866] | [867] | [868] | [869] | [870] | [871] | [872] |