REACTOME_RESOLUTION_OF_D_LOOP_STRUCTURES			Return to index
Order	Gene	Description	ref_hepatocyte	HepG2	HepG2.C3A	HuH.7	SNU475	THLE	liver
1	RAD51C	DNA repair protein RAD51 homolog 3	[1]	-0.71[2]	-1.38[3]	-1.58[4]	-3.05[5]	-1.58[6]	-2.74[7]
2	SLX1A	Structure-specific endonuclease subunit SLX1	[8]	[9]	[10]	[11]	[12]	[13]	[14]
3	SLX1B		[15]	[16]	[17]	[18]	[19]	[20]	[21]
4	KAT5	Histone acetyltransferase KAT5	[22]	-1.08[23]	-1.56[24]	-2.63[25]	-1.70[26]	-1.86[27]	-1.56[28]
5	MUS81	Crossover junction endonuclease MUS81	[29]	-0.51[30]	-1.19[31]	-1.49[32]	-0.46[33]	-0.80[34]	-1.05[35]
6	NBN	Nibrin	[36]	-0.72[37]	-0.44[38]	-0.72[39]	0.64[40]	-0.32[41]	0.78[42]
7	RAD51	DNA repair protein RAD51 homolog 1	[43]	-0.56[44]	-1.63[45]	-1.57[46]	-1.05[47]	-1.16[48]	-4.43[49]
8	RAD50	DNA repair protein RAD50	[50]	-0.15[51]	1.09[52]	0.20[53]	0.40[54]	0.81[55]	1.72[56]
9	RMI2	RecQ-mediated genome instability protein 2	[57]	0.95[58]	-0.66[59]	-0.75[60]	-2.06[61]	-1.83[62]	-4.92[63]
10	RBBP8	DNA endonuclease RBBP8	[64]	-0.11[65]	0.41[66]	-1.00[67]	0.57[68]	0.69[69]	-0.24[70]
11	TOP3A	DNA topoisomerase 3-alpha	[71]	1.66[72]	0.44[73]	0.70[74]	0.98[75]	1.29[76]	1.31[77]
12	PALB2	Partner and localizer of BRCA2	[78]	1.46[79]	0.87[80]	0.46[81]	-0.17[82]	0.25[83]	0.18[84]
13	BRCA1	Breast cancer type 1 susceptibility protein	[85]	1.37[86]	1.72[87]	2.07[88]	1.28[89]	1.72[90]	1.19[91]
14	RTEL1	Regulator of telomere elongation helicase 1	[92]	-2.01[93]	-1.77[94]	-3.62[95]	-3.15[96]	-2.66[97]	-2.14[98]
15	WRN	Werner syndrome ATP-dependent helicase	[99]	0.31[100]	0.87[101]	2.77[102]	0.83[103]	0.57[104]	1.48[105]
16	RAD51D	DNA repair protein RAD51 homolog 4	[106]	0.42[107]	-0.46[108]	0.23[109]	0.19[110]	-0.46[111]	-0.73[112]
17	RAD51AP1	RAD51-associated protein 1	[113]	1.20[114]	1.76[115]	2.42[116]	1.20[117]	1.93[118]	-2.00[119]
18	RMI1	RecQ-mediated genome instability protein 1	[120]	0.28[121]	0.62[122]	1.03[123]	1.21[124]	1.98[125]	0.50[126]
19	XRCC2	DNA repair protein XRCC2	[127]	-0.13[128]	-0.23[129]	0.08[130]	-0.06[131]	0.11[132]	-2.75[133]
20	ATM	Serine-protein kinase ATM	[134]	2.73[135]	3.44[136]	3.12[137]	3.29[138]	2.69[139]	4.50[140]
21	RAD51B	DNA repair protein RAD51 homolog 2	[141]	-0.45[142]	-1.22[143]	-1.24[144]	-0.80[145]	-1.06[146]	-1.03[147]
22	GEN1	Flap endonuclease GEN homolog 1	[148]	0.80[149]	2.10[150]	1.17[151]	1.66[152]	1.86[153]	2.00[154]
23	DNA2	DNA replication ATP-dependent helicase/nuclease DNA2	[155]	1.46[156]	2.33[157]	1.50[158]	1.78[159]	1.36[160]	1.07[161]
24	EXO1	Exonuclease 1	[162]	1.60[163]	0.99[164]	2.12[165]	2.91[166]	2.12[167]	-1.96[168]
25	XRCC3	DNA repair protein XRCC3	[169]	2.74[170]	2.02[171]	1.69[172]	2.32[173]	2.69[174]	1.22[175]
26	BRIP1	Fanconi anemia group J protein	[176]	1.84[177]	2.35[178]	2.32[179]	2.34[180]	2.31[181]	1.47[182]
27	BLM	Bloom syndrome protein	[183]	1.24[184]	1.70[185]	2.47[186]	2.03[187]	2.03[188]	-0.87[189]
28	EME1	Crossover junction endonuclease EME1	[190]	2.26[191]	2.01[192]	2.76[193]	2.01[194]	1.83[195]	-1.97[196]
29	BARD1	BRCA1-associated RING domain protein 1	[197]	1.01[198]	1.11[199]	1.09[200]	1.83[201]	1.84[202]	1.38[203]
30	SLX4	Structure-specific endonuclease subunit SLX4	[204]	2.61[205]	1.89[206]	2.40[207]	2.23[208]	2.38[209]	1.78[210]
31	BRCA2	Breast cancer type 2 susceptibility protein	[211]	2.50[212]	4.09[213]	4.23[214]	3.61[215]	3.68[216]	2.95[217]
32	EME2	Probable crossover junction endonuclease EME2	[218]	1.45[219]	1.08[220]	0.50[221]	0.48[222]	0.66[223]	2.33[224]
33	MRE11	Double-strand break repair protein MRE11	[225]	[226]	[227]	[228]	[229]	[230]	[231]
34	SPIDR	DNA repair-scaffolding protein	[232]	[233]	[234]	[235]	[236]	[237]	[238]