REACTOME_REPRESSION_OF_WNT_TARGET_GENES Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 MYC Myc proto-oncogene protein [1] -0.46[2] -0.34[3] -2.56[4] -2.96[5] -0.62[6] -1.61[7]
2 HDAC1 Histone deacetylase 1 [8] -0.38[9] 0.09[10] 0.59[11] 0.47[12] 0.23[13] -0.07[14]
3 CTBP1 C-terminal-binding protein 1 [15] -0.84[16] -0.27[17] -0.18[18] 0.24[19] -0.75[20] 0.13[21]
4 TLE1 Transducin-like enhancer protein 1 [22] 0.68[23] 0.52[24] -0.40[25] -0.08[26] -0.29[27] 0.73[28]
5 AXIN2 Axin-2 [29] 2.58[30] 0.64[31] -3.60[32] -1.26[33] -1.66[34] -1.95[35]
6 TLE3 Transducin-like enhancer protein 3 [36] -0.52[37] -0.31[38] 2.21[39] 2.17[40] 1.72[41] 0.67[42]
7 TCF7L2 Transcription factor 7-like 2 [43] -0.02[44] 1.20[45] 1.21[46] 0.52[47] 0.48[48] 2.11[49]
8 TCF7L1 Transcription factor 7-like 1 [50] -3.94[51] -1.68[52] 0.33[53] -1.99[54] -1.90[55] 0.69[56]
9 TCF7 Transcription factor 7 [57] 1.55[58] 0.66[59] -0.47[60] -0.01[61] -0.35[62] 0.02[63]
10 CTBP2 C-terminal-binding protein 2 [64] -2.95[65] -2.06[66] 1.47[67] 3.11[68] 3.36[69] 1.94[70]
11 TLE2 Transducin-like enhancer protein 2 [71] -3.50[72] -2.50[73] 2.85[74] -2.09[75] 0.65[76] 1.07[77]
12 TLE4 Transducin-like enhancer protein 4 [78] 0.50[79] 3.10[80] 1.73[81] -0.06[82] 2.86[83] 2.66[84]
13 LEF1 Lymphoid enhancer-binding factor 1 [85] 1.76[86] -4.71[87] 3.02[88] 0.91[89] -0.82[90] 1.48[91]
14 TLE5 [92] [93] [94] [95] [96] [97] [98]
[1]
ref_hepatocyte MYC
Mean 29.9
Standard deviation 34
Values 15 20 89 23 1.4
[2]
HepG2 MYC
Mean 88.8
Standard deviation 53
Values 1.3e+02 52
[3]
HepG2.C3A MYC
Mean 62.6
Standard deviation 15
Values 73 52
[4]
HuH.7 MYC
Mean 14.7
Standard deviation 2.6
Values 13 18 14
[5]
SNU475 MYC
Mean 7.93
Standard deviation 1.4
Values 6.9 8.9
[6]
THLE MYC
Mean 46
Standard deviation 10
Values 39 53
[7]
liver MYC
Mean 10.6
Standard deviation 6
Values 18 5.9 13 5.5
[8]
ref_hepatocyte HDAC1
Mean 20.8
Standard deviation 4.1
Values 22 28 19 18 18
[9]
HepG2 HDAC1
Mean 65.4
Standard deviation 11
Values 73 58
[10]
HepG2.C3A HDAC1
Mean 58.9
Standard deviation 2.3
Values 57 60
[11]
HuH.7 HDAC1
Mean 90.9
Standard deviation 22
Values 94 68 1.1e+02
[12]
SNU475 HDAC1
Mean 59.8
Standard deviation 8
Values 65 54
[13]
THLE HDAC1
Mean 57.8
Standard deviation 6.8
Values 53 63
[14]
liver HDAC1
Mean 21.5
Standard deviation 6.8
Values 25 18 29 14
[15]
ref_hepatocyte CTBP1
Mean 20.8
Standard deviation 6
Values 27 15 15 21 26
[16]
HepG2 CTBP1
Mean 47.8
Standard deviation 0.87
Values 47 48
[17]
HepG2.C3A CTBP1
Mean 45.9
Standard deviation 6.8
Values 51 41
[18]
HuH.7 CTBP1
Mean 53.5
Standard deviation 12
Values 56 40 65
[19]
SNU475 CTBP1
Mean 50.8
Standard deviation 9.4
Values 58 44
[20]
THLE CTBP1
Mean 29.4
Standard deviation 4.8
Values 26 33
[21]
liver CTBP1
Mean 24.6
Standard deviation 4.6
Values 26 24 19 30
[22]
ref_hepatocyte TLE1
Mean 7.22
Standard deviation 2.6
Values 4.8 4.4 11 8.4 7.9
[23]
HepG2 TLE1
Mean 47.1
Standard deviation 7
Values 52 42
[24]
HepG2.C3A TLE1
Mean 27.4
Standard deviation 8.4
Values 33 21
[25]
HuH.7 TLE1
Mean 15.9
Standard deviation 2.1
Values 15 14 18
[26]
SNU475 TLE1
Mean 14.2
Standard deviation 1.2
Values 13 15
[27]
THLE TLE1
Mean 13.9
Standard deviation 1.3
Values 13 15
[28]
liver TLE1
Mean 13
Standard deviation 3.7
Values 15 11 9 17
[29]
ref_hepatocyte AXIN2
Mean 3.77
Standard deviation 8.1
Values 18 0 0.16 0.14 0.24
[30]
HepG2 AXIN2
Mean 92
Standard deviation 17
Values 1e+02 80
[31]
HepG2.C3A AXIN2
Mean 15.6
Standard deviation 6.3
Values 11 20
[32]
HuH.7 AXIN2
Mean 0.905
Standard deviation 0.058
Values 0.96 0.91 0.84
[33]
SNU475 AXIN2
Mean 3.25
Standard deviation 0.69
Values 3.7 2.8
[34]
THLE AXIN2
Mean 2.82
Standard deviation 0.56
Values 3.2 2.4
[35]
liver AXIN2
Mean 1.06
Standard deviation 0.52
Values 0.68 1.2 0.59 1.7
[36]
ref_hepatocyte TLE3
Mean 2.46
Standard deviation 2
Values 3.3 0.7 5.6 1.6 1.1
[37]
HepG2 TLE3
Mean 7
Standard deviation 2.8
Values 9 5
[38]
HepG2.C3A TLE3
Mean 5.26
Standard deviation 1.5
Values 6.3 4.2
[39]
HuH.7 TLE3
Mean 33
Standard deviation 5
Values 35 37 27
[40]
SNU475 TLE3
Mean 22.9
Standard deviation 3.9
Values 20 26
[41]
THLE TLE3
Mean 19.2
Standard deviation 3.5
Values 17 22
[42]
liver TLE3
Mean 4.24
Standard deviation 1.1
Values 2.9 5.5 4.7 3.9
[43]
ref_hepatocyte TCF7L2
Mean 2.36
Standard deviation 1.2
Values 1.7 1.3 4.4 1.9 2.5
[44]
HepG2 TCF7L2
Mean 9.52
Standard deviation 1.6
Values 11 8.4
[45]
HepG2.C3A TCF7L2
Mean 14.4
Standard deviation 3.4
Values 17 12
[46]
HuH.7 TCF7L2
Mean 15.9
Standard deviation 1.6
Values 18 16 15
[47]
SNU475 TCF7L2
Mean 7.02
Standard deviation 1.3
Values 7.9 6.1
[48]
THLE TCF7L2
Mean 7.78
Standard deviation 0.97
Values 7.1 8.5
[49]
liver TCF7L2
Mean 11.1
Standard deviation 8.5
Values 21 3.4 14 5
[50]
ref_hepatocyte TCF7L1
Mean 1.79
Standard deviation 1.6
Values 0.2 0.6 4.2 2.4 1.6
[51]
HepG2 TCF7L1
Mean 0.477
Standard deviation 0.1
Values 0.55 0.4
[52]
HepG2.C3A TCF7L1
Mean 1.48
Standard deviation 0.7
Values 2 0.99
[53]
HuH.7 TCF7L1
Mean 6.53
Standard deviation 0.65
Values 5.9 7.2 6.4
[54]
SNU475 TCF7L1
Mean 0.932
Standard deviation 0.52
Values 0.57 1.3
[55]
THLE TCF7L1
Mean 1.14
Standard deviation 0.018
Values 1.1 1.1
[56]
liver TCF7L1
Mean 3.12
Standard deviation 2.9
Values 7.2 1 3.2 1.1
[57]
ref_hepatocyte TCF7
Mean 1.74
Standard deviation 2
Values 5.2 0.67 0.54 0.79 1.5
[58]
HepG2 TCF7
Mean 20.8
Standard deviation 2.1
Values 22 19
[59]
HepG2.C3A TCF7
Mean 7.29
Standard deviation 0.88
Values 6.7 7.9
[60]
HuH.7 TCF7
Mean 3.64
Standard deviation 1.4
Values 5 2.2 3.7
[61]
SNU475 TCF7
Mean 3.57
Standard deviation 2
Values 2.2 5
[62]
THLE TCF7
Mean 3.23
Standard deviation 0.38
Values 3 3.5
[63]
liver TCF7
Mean 1.91
Standard deviation 0.66
Values 2.2 1.6 1.2 2.7
[64]
ref_hepatocyte CTBP2
Mean 1.21
Standard deviation 0.49
Values 2 0.82 1.1 0.82 1.3
[65]
HepG2 CTBP2
Mean 0.64
Standard deviation 0.5
Values 1 0.28
[66]
HepG2.C3A CTBP2
Mean 0.77
Standard deviation 0.13
Values 0.87 0.68
[67]
HuH.7 CTBP2
Mean 9.77
Standard deviation 1.8
Values 11 7.8 10
[68]
SNU475 CTBP2
Mean 21.6
Standard deviation 0.38
Values 22 21
[69]
THLE CTBP2
Mean 29.5
Standard deviation 3.9
Values 27 32
[70]
liver CTBP2
Mean 5.02
Standard deviation 0.65
Values 4.7 4.4 5.2 5.9
[71]
ref_hepatocyte TLE2
Mean 1.05
Standard deviation 1.3
Values 0 0.36 0 2 2.9
[72]
HepG2 TLE2
Mean 0.38
Standard deviation 0.31
Values 0.6 0.16
[73]
HepG2.C3A TLE2
Mean 0.497
Standard deviation 0.37
Values 0.76 0.24
[74]
HuH.7 TLE2
Mean 22.1
Standard deviation 4
Values 20 27 19
[75]
SNU475 TLE2
Mean 0.514
Standard deviation 0.24
Values 0.34 0.68
[76]
THLE TLE2
Mean 3.9
Standard deviation 2
Values 5.3 2.5
[77]
liver TLE2
Mean 2.39
Standard deviation 0.77
Values 3.1 1.5 2 2.9
[78]
ref_hepatocyte TLE4
Mean 0.384
Standard deviation 0.23
Values 0.22 0.15 0.3 0.62 0.63
[79]
HepG2 TLE4
Mean 2.23
Standard deviation 0.018
Values 2.2 2.2
[80]
HepG2.C3A TLE4
Mean 8.74
Standard deviation 0.85
Values 9.3 8.1
[81]
HuH.7 TLE4
Mean 3.7
Standard deviation 0.26
Values 3.7 3.5 4
[82]
SNU475 TLE4
Mean 0.761
Standard deviation 0.49
Values 0.41 1.1
[83]
THLE TLE4
Mean 6.59
Standard deviation 1
Values 5.9 7.3
[84]
liver TLE4
Mean 2.64
Standard deviation 0.52
Values 3.3 2.4 2.1 2.8
[85]
ref_hepatocyte LEF1
Mean 0.0478
Standard deviation 0.085
Values 0 0 0.2 0.043 0
[86]
HepG2 LEF1
Mean 0.663
Standard deviation 0.44
Values 0.97 0.35
[87]
HepG2.C3A LEF1
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[88]
HuH.7 LEF1
Mean 1.13
Standard deviation 0.42
Values 1 1.6 0.77
[89]
SNU475 LEF1
Mean 0.186
Standard deviation 0.2
Values 0.042 0.33
[90]
THLE LEF1
Mean 0.0639
Standard deviation 0.015
Values 0.053 0.074
[91]
liver LEF1
Mean 0.144
Standard deviation 0.047
Values 0.21 0.13 0.1 0.13
[92]
ref_hepatocyte TLE5
Missing
[93]
HepG2 TLE5
Missing
[94]
HepG2.C3A TLE5
Missing
[95]
HuH.7 TLE5
Missing
[96]
SNU475 TLE5
Missing
[97]
THLE TLE5
Missing
[98]
liver TLE5
Missing