REACTOME_RELEASE_OF_HH_NP_FROM_THE_SECRETING_CELL Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 NOTUM Palmitoleoyl-protein carboxylesterase NOTUM [1] 0.94[2] 0.76[3] -2.31[4] -6.82[5] -6.40[6] -2.20[7]
2 ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 [8] -2.51[9] -1.30[10] -0.02[11] 1.21[12] 1.26[13] 0.59[14]
3 SHH Sonic hedgehog protein [15] -2.80[16] -1.63[17] -0.01[18] -7.71[19] -6.93[20] 0.64[21]
4 IHH Indian hedgehog protein [22] -2.13[23] -2.75[24] 4.60[25] -4.82[26] -4.77[27] 0.60[28]
5 GPC5 Glypican-5 [29] -6.37[30] -6.36[31] -0.44[32] -3.77[33] -2.34[34] 4.08[35]
6 DISP2 Protein dispatched homolog 2 [36] -0.18[37] -1.22[38] 3.27[39] 3.45[40] 0.60[41] 1.78[42]
7 SCUBE2 Signal peptide, CUB and EGF-like domain-containing protein 2 [43] -7.79[44] -4.40[45] -1.70[46] 1.82[47] 1.57[48] 2.82[49]
8 DHH Desert hedgehog protein [50] [51] [52] [53] [54] [55] [56]
[1]
ref_hepatocyte NOTUM
Mean 5.85
Standard deviation 11
Values 26 0 0.54 1.6 1.1
[2]
HepG2 NOTUM
Mean 225
Standard deviation 1.2e+02
Values 3.1e+02 1.4e+02
[3]
HepG2.C3A NOTUM
Mean 70.6
Standard deviation 22
Values 86 55
[4]
HuH.7 NOTUM
Mean 2.77
Standard deviation 0.68
Values 2.9 2 3.4
[5]
SNU475 NOTUM
Mean 0.137
Standard deviation 0.11
Values 0.22 0.056
[6]
THLE NOTUM
Mean 0.109
Standard deviation 0.087
Values 0.047 0.17
[7]
liver NOTUM
Mean 1.27
Standard deviation 1.1
Values 2.2 0.36 0.26 2.3
[8]
ref_hepatocyte ADAM17
Mean 5.04
Standard deviation 4.3
Values 10 8.5 4.3 1 1.1
[9]
HepG2 ADAM17
Mean 17.8
Standard deviation 0.96
Values 18 17
[10]
HepG2.C3A ADAM17
Mean 14.6
Standard deviation 0.94
Values 14 15
[11]
HuH.7 ADAM17
Mean 11.7
Standard deviation 1.5
Values 13 12 10
[12]
SNU475 ADAM17
Mean 31
Standard deviation 2.8
Values 33 29
[13]
THLE ADAM17
Mean 19
Standard deviation 2.3
Values 17 21
[14]
liver ADAM17
Mean 7.57
Standard deviation 0.72
Values 7.2 8.6 7 7.4
[15]
ref_hepatocyte SHH
Mean 1.15
Standard deviation 1
Values 0.23 0 2.5 1.4 1.6
[16]
HepG2 SHH
Mean 3.31
Standard deviation 2.1
Values 4.8 1.8
[17]
HepG2.C3A SHH
Mean 2.66
Standard deviation 0.92
Values 3.3 2
[18]
HuH.7 SHH
Mean 2.69
Standard deviation 0.5
Values 2.5 3.3 2.3
[19]
SNU475 SHH
Mean 0.0146
Standard deviation 0.00091
Values 0.014 0.015
[20]
THLE SHH
Mean 0.0148
Standard deviation 0.021
Values 0.03 0
[21]
liver SHH
Mean 1.79
Standard deviation 2.1
Values 0.12 2.9 0 4.1
[22]
ref_hepatocyte IHH
Mean 0.19
Standard deviation 0.27
Values 0 0.054 0 0.28 0.62
[23]
HepG2 IHH
Mean 0.871
Standard deviation 0.39
Values 0.6 1.1
[24]
HepG2.C3A IHH
Mean 0.201
Standard deviation 0.05
Values 0.17 0.24
[25]
HuH.7 IHH
Mean 10.8
Standard deviation 0.98
Values 9.7 11 11
[26]
SNU475 IHH
Mean 0.0177
Standard deviation 0.025
Values 0 0.035
[27]
THLE IHH
Mean 0.0109
Standard deviation 0.0071
Values 0.0059 0.016
[28]
liver IHH
Mean 0.288
Standard deviation 0.17
Values 0.49 0.17 0.13 0.36
[29]
ref_hepatocyte GPC5
Mean 0.0619
Standard deviation 0.066
Values 0 0 0.14 0.052 0.11
[30]
HepG2 GPC5
Mean 0.015
Standard deviation 0.0031
Values 0.017 0.013
[31]
HepG2.C3A GPC5
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[32]
HuH.7 GPC5
Mean 0.107
Standard deviation 0.094
Values 0.082 0.21 0.028
[33]
SNU475 GPC5
Mean 0.012
Standard deviation 0.0027
Values 0.014 0.01
[34]
THLE GPC5
Mean 0.0192
Standard deviation 0.01
Values 0.012 0.027
[35]
liver GPC5
Mean 1.04
Standard deviation 0.64
Values 2 0.83 0.72 0.64
[36]
ref_hepatocyte DISP2
Mean 0.0454
Standard deviation 0.043
Values 0 0.093 0.073 0.06 0
[37]
HepG2 DISP2
Mean 0.802
Standard deviation 0.073
Values 0.75 0.85
[38]
HepG2.C3A DISP2
Mean 0.139
Standard deviation 0.031
Values 0.12 0.16
[39]
HuH.7 DISP2
Mean 1.03
Standard deviation 0.09
Values 1.1 0.93 1
[40]
SNU475 DISP2
Mean 1.31
Standard deviation 0.13
Values 1.4 1.2
[41]
THLE DISP2
Mean 0.109
Standard deviation 0.02
Values 0.095 0.12
[42]
liver DISP2
Mean 0.155
Standard deviation 0.12
Values 0 0.27 0.23 0.12
[43]
ref_hepatocyte SCUBE2
Mean 0.0317
Standard deviation 0.044
Values 0 0 0 0.069 0.089
[44]
HepG2 SCUBE2
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[45]
HepG2.C3A SCUBE2
Mean 0.0107
Standard deviation 0.015
Values 0 0.021
[46]
HuH.7 SCUBE2
Mean 0.023
Standard deviation 0.025
Values 0.0082 0.051 0.0094
[47]
SNU475 SCUBE2
Mean 0.296
Standard deviation 0.1
Values 0.22 0.37
[48]
THLE SCUBE2
Mean 0.148
Standard deviation 0.00074
Values 0.15 0.15
[49]
liver SCUBE2
Mean 0.223
Standard deviation 0.15
Values 0.024 0.4 0.23 0.24
[50]
ref_hepatocyte DHH
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[51]
HepG2 DHH
Mean 0.00716
Standard deviation 0.002
Values 0.0057 0.0086
[52]
HepG2.C3A DHH
Mean 0.00972
Standard deviation 0.014
Values 0.019 0
[53]
HuH.7 DHH
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[54]
SNU475 DHH
Mean 0.00696
Standard deviation 0.0098
Values 0.014 0
[55]
THLE DHH
Mean 0.0225
Standard deviation 0.0017
Values 0.024 0.021
[56]
liver DHH
Mean 0.03
Standard deviation 0.051
Values 0 0.014 0 0.11