REACTOME_RELEASE_OF_APOPTOTIC_FACTORS_FROM_THE_MITOCHONDRIA Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 BAX Apoptosis regulator BAX [1] 0.11[2] -0.64[3] -0.93[4] -1.53[5] -1.19[6] -3.54[7]
2 GSDMD Gasdermin-D [8] -2.14[9] -1.28[10] -1.78[11] -1.19[12] -2.30[13] -0.24[14]
3 DIABLO Diablo homolog, mitochondrial [15] -0.37[16] -0.06[17] -0.20[18] -0.26[19] -0.54[20] -0.32[21]
4 CYCS Cytochrome c [22] 1.11[23] 1.36[24] 1.60[25] 1.41[26] 1.77[27] 1.73[28]
5 BAK1 Bcl-2 homologous antagonist/killer [29] 0.67[30] 0.26[31] 0.39[32] 1.27[33] 0.70[34] -1.37[35]
6 GSDME Gasdermin-E [36] [37] [38] [39] [40] [41] [42]
7 SEPTIN4 [43] [44] [45] [46] [47] [48] [49]

[1]
ref_hepatocyte BAX
Mean 24.8
Standard deviation 9.1
Values 30 21 34 27 11
[2]
HepG2 BAX
Mean 68.8
Standard deviation 16
Values 80 58
[3]
HepG2.C3A BAX
Mean 35.4
Standard deviation 3
Values 38 33
[4]
HuH.7 BAX
Mean 24.6
Standard deviation 9.8
Values 26 14 34
[5]
SNU475 BAX
Mean 15
Standard deviation 0.87
Values 14 16
[6]
THLE BAX
Mean 21.9
Standard deviation 0.028
Values 22 22
[7]
liver BAX
Mean 2.27
Standard deviation 0.64
Values 2.3 2.5 2.9 1.4
[8]
ref_hepatocyte GSDMD
Mean 24
Standard deviation 21
Values 5.5 9.4 14 55 36
[9]
HepG2 GSDMD
Mean 14
Standard deviation 2.3
Values 12 16
[10]
HepG2.C3A GSDMD
Mean 22
Standard deviation 2.9
Values 24 20
[11]
HuH.7 GSDMD
Mean 13.3
Standard deviation 4.2
Values 14 8.8 17
[12]
SNU475 GSDMD
Mean 18.4
Standard deviation 3.2
Values 21 16
[13]
THLE GSDMD
Mean 9.83
Standard deviation 1.7
Values 11 8.6
[14]
liver GSDMD
Mean 21.7
Standard deviation 5.3
Values 29 16 19 23
[15]
ref_hepatocyte DIABLO
Mean 16.2
Standard deviation 5.1
Values 11 14 24 15 17
[16]
HepG2 DIABLO
Mean 32.4
Standard deviation 1.1
Values 32 33
[17]
HepG2.C3A DIABLO
Mean 34.5
Standard deviation 2.7
Values 33 36
[18]
HuH.7 DIABLO
Mean 26.8
Standard deviation 4.5
Values 26 23 32
[19]
SNU475 DIABLO
Mean 23.7
Standard deviation 0.05
Values 24 24
[20]
THLE DIABLO
Mean 22.5
Standard deviation 0.81
Values 22 23
[21]
liver DIABLO
Mean 13.9
Standard deviation 8.5
Values 22 7.3 21 5.8
[22]
ref_hepatocyte CYCS
Mean 14.3
Standard deviation 4.3
Values 16 19 7.5 15 14
[23]
HepG2 CYCS
Mean 79.8
Standard deviation 18
Values 67 93
[24]
HepG2.C3A CYCS
Mean 81.4
Standard deviation 39
Values 54 1.1e+02
[25]
HuH.7 CYCS
Mean 82.3
Standard deviation 19
Values 93 60 94
[26]
SNU475 CYCS
Mean 66.3
Standard deviation 0.99
Values 66 67
[27]
THLE CYCS
Mean 98.4
Standard deviation 7.6
Values 93 1e+02
[28]
liver CYCS
Mean 50.8
Standard deviation 34
Values 59 30 95 19
[29]
ref_hepatocyte BAK1
Mean 6.08
Standard deviation 5.2
Values 2.6 8.3 14 2.7 2.6
[30]
HepG2 BAK1
Mean 24.9
Standard deviation 3.2
Values 27 23
[31]
HepG2.C3A BAK1
Mean 16.2
Standard deviation 1.2
Values 15 17
[32]
HuH.7 BAK1
Mean 15.2
Standard deviation 1.3
Values 16 14 16
[33]
SNU475 BAK1
Mean 25.4
Standard deviation 4.7
Values 29 22
[34]
THLE BAK1
Mean 19.9
Standard deviation 2.1
Values 18 21
[35]
liver BAK1
Mean 2.5
Standard deviation 0.66
Values 2.5 2.5 3.3 1.7
[36]
ref_hepatocyte GSDME
Missing
[37]
HepG2 GSDME
Missing
[38]
HepG2.C3A GSDME
Missing
[39]
HuH.7 GSDME
Missing
[40]
SNU475 GSDME
Missing
[41]
THLE GSDME
Missing
[42]
liver GSDME
Missing
[43]
ref_hepatocyte SEPTIN4
Missing
[44]
HepG2 SEPTIN4
Missing
[45]
HepG2.C3A SEPTIN4
Missing
[46]
HuH.7 SEPTIN4
Missing
[47]
SNU475 SEPTIN4
Missing
[48]
THLE SEPTIN4
Missing
[49]
liver SEPTIN4
Missing