REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ASSOCIATION_WITH_CO_FACTORS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 AKT1 RAC-alpha serine/threonine-protein kinase [1] -0.48[2] -0.62[3] -1.77[4] -1.02[5] -0.60[6] -0.55[7]
2 AKT2 RAC-beta serine/threonine-protein kinase [8] 0.40[9] 0.77[10] 0.82[11] -0.11[12] 0.08[13] 0.83[14]
3 TP53BP2 Apoptosis-stimulating of p53 protein 2 [15] -1.17[16] -0.74[17] 0.77[18] 0.28[19] -0.02[20] -0.25[21]
4 TP53 Cellular tumor antigen p53 [22] 1.08[23] 0.73[24] 1.42[25] 0.32[26] 0.39[27] -0.35[28]
5 BANP Protein BANP [29] -1.02[30] 0.21[31] -0.79[32] -1.36[33] -1.28[34] 0.09[35]
6 PPP1R13L RelA-associated inhibitor [36] -0.16[37] -0.84[38] 0.82[39] 0.36[40] 0.06[41] -2.09[42]
7 PHF20 PHD finger protein 20 [43] 1.57[44] 1.45[45] 1.93[46] 2.23[47] 1.66[48] 1.45[49]
8 PPP1R13B Apoptosis-stimulating of p53 protein 1 [50] 0.98[51] 0.38[52] -0.62[53] -0.03[54] 0.23[55] 0.68[56]
9 ZNF385A Zinc finger protein 385A [57] 0.99[58] -1.97[59] -1.12[60] 0.61[61] 1.09[62] -0.69[63]
10 AKT3 RAC-gamma serine/threonine-protein kinase [64] -2.40[65] -4.87[66] -4.25[67] 4.87[68] 4.23[69] 3.30[70]
11 TP73 Tumor protein p73 [71] 0.16[72] 2.81[73] 1.66[74] -0.30[75] 1.24[76] 0.35[77]
12 TP63 Tumor protein 63 [78] [79] [80] -2.61[81] -2.35[82] -5.52[83] -1.78[84]
13 POU4F1 POU domain, class 4, transcription factor 1 [85] 6.99[86] 7.71[87] -1.07[88] -1.54[89] [90] -0.74[91]
14 POU4F2 POU domain, class 4, transcription factor 2 [92] [93] [94] [95] [96] [97] [98]
[1]
ref_hepatocyte AKT1
Mean 37.6
Standard deviation 15
Values 55 50 19 31 32
[2]
HepG2 AKT1
Mean 87.8
Standard deviation 2.3
Values 89 86
[3]
HepG2.C3A AKT1
Mean 66.6
Standard deviation 2.4
Values 65 68
[4]
HuH.7 AKT1
Mean 30.2
Standard deviation 6.6
Values 33 23 35
[5]
SNU475 AKT1
Mean 66.6
Standard deviation 14
Values 76 57
[6]
THLE AKT1
Mean 75.8
Standard deviation 6.1
Values 72 80
[7]
liver AKT1
Mean 45.1
Standard deviation 25
Values 34 48 20 79
[8]
ref_hepatocyte AKT2
Mean 10.6
Standard deviation 2.8
Values 7.2 8.4 11 13 14
[9]
HepG2 AKT2
Mean 45.6
Standard deviation 3.3
Values 48 43
[10]
HepG2.C3A AKT2
Mean 49.1
Standard deviation 8.9
Values 55 43
[11]
HuH.7 AKT2
Mean 51.5
Standard deviation 9.8
Values 59 41 55
[12]
SNU475 AKT2
Mean 35.3
Standard deviation 5.9
Values 39 31
[13]
THLE AKT2
Mean 34.2
Standard deviation 3.5
Values 32 37
[14]
liver AKT2
Mean 33
Standard deviation 9.4
Values 24 36 27 45
[15]
ref_hepatocyte TP53BP2
Mean 6.24
Standard deviation 6.5
Values 2.6 7.1 17 2.4 2
[16]
HepG2 TP53BP2
Mean 9.07
Standard deviation 1.2
Values 8.2 9.9
[17]
HepG2.C3A TP53BP2
Mean 10.2
Standard deviation 0.052
Values 10 10
[18]
HuH.7 TP53BP2
Mean 29.1
Standard deviation 12
Values 24 43 20
[19]
SNU475 TP53BP2
Mean 27.4
Standard deviation 1.5
Values 26 28
[20]
THLE TP53BP2
Mean 18.7
Standard deviation 0.31
Values 19 19
[21]
liver TP53BP2
Mean 9.23
Standard deviation 1.2
Values 8.3 11 8.1 9.9
[22]
ref_hepatocyte TP53
Mean 5.28
Standard deviation 0.94
Values 5.5 3.7 6.2 5.5 5.5
[23]
HepG2 TP53
Mean 36.3
Standard deviation 0.12
Values 36 36
[24]
HepG2.C3A TP53
Mean 23.9
Standard deviation 1.8
Values 23 25
[25]
HuH.7 TP53
Mean 38.7
Standard deviation 16
Values 50 20 46
[26]
SNU475 TP53
Mean 23.7
Standard deviation 6.7
Values 28 19
[27]
THLE TP53
Mean 21.1
Standard deviation 6.6
Values 16 26
[28]
liver TP53
Mean 7.29
Standard deviation 2.3
Values 9 5 9.5 5.6
[29]
ref_hepatocyte BANP
Mean 3.65
Standard deviation 1.2
Values 3.4 2.6 5.7 3.7 2.8
[30]
HepG2 BANP
Mean 5.87
Standard deviation 0.76
Values 6.4 5.3
[31]
HepG2.C3A BANP
Mean 11.5
Standard deviation 1.6
Values 13 10
[32]
HuH.7 BANP
Mean 5.76
Standard deviation 0.87
Values 5.4 5.1 6.8
[33]
SNU475 BANP
Mean 5.13
Standard deviation 0.16
Values 5 5.2
[34]
THLE BANP
Mean 4.59
Standard deviation 0.69
Values 4.1 5.1
[35]
liver BANP
Mean 6.81
Standard deviation 3.5
Values 3.1 11 4.7 8.8
[36]
ref_hepatocyte PPP1R13L
Mean 2.88
Standard deviation 4.2
Values 0.23 2.1 10 1.1 0.69
[37]
HepG2 PPP1R13L
Mean 8.4
Standard deviation 1.5
Values 9.4 7.4
[38]
HepG2.C3A PPP1R13L
Mean 4.38
Standard deviation 1.5
Values 5.5 3.3
[39]
HuH.7 PPP1R13L
Mean 13.9
Standard deviation 0.76
Values 13 14 15
[40]
SNU475 PPP1R13L
Mean 13.3
Standard deviation 4.9
Values 17 9.9
[41]
THLE PPP1R13L
Mean 9.14
Standard deviation 1.3
Values 10 8.2
[42]
liver PPP1R13L
Mean 1.18
Standard deviation 0.46
Values 1.4 0.73 0.87 1.7
[43]
ref_hepatocyte PHF20
Mean 2.01
Standard deviation 1
Values 3.4 2.8 1.4 1.2 1.3
[44]
HepG2 PHF20
Mean 19.5
Standard deviation 1.2
Values 19 20
[45]
HepG2.C3A PHF20
Mean 15
Standard deviation 0.61
Values 15 15
[46]
HuH.7 PHF20
Mean 21.1
Standard deviation 3.1
Values 24 21 18
[47]
SNU475 PHF20
Mean 34.1
Standard deviation 4.1
Values 37 31
[48]
THLE PHF20
Mean 19.4
Standard deviation 2.6
Values 18 21
[49]
liver PHF20
Mean 9.65
Standard deviation 1.1
Values 11 9 9.3 8.9
[50]
ref_hepatocyte PPP1R13B
Mean 1.88
Standard deviation 0.66
Values 2.2 2 2.8 1.3 1.2
[51]
HepG2 PPP1R13B
Mean 12.1
Standard deviation 1.7
Values 11 13
[52]
HepG2.C3A PPP1R13B
Mean 6.62
Standard deviation 0.98
Values 7.3 5.9
[53]
HuH.7 PPP1R13B
Mean 3.36
Standard deviation 0.41
Values 3.6 2.9 3.6
[54]
SNU475 PPP1R13B
Mean 6.65
Standard deviation 1.5
Values 7.7 5.6
[55]
THLE PPP1R13B
Mean 6.74
Standard deviation 0.32
Values 6.5 7
[56]
liver PPP1R13B
Mean 5.29
Standard deviation 1.2
Values 6.1 5.5 3.5 6.1
[57]
ref_hepatocyte ZNF385A
Mean 0.819
Standard deviation 0.82
Values 0.052 0 2 1 1
[58]
HepG2 ZNF385A
Mean 5.3
Standard deviation 1.7
Values 6.5 4.1
[59]
HepG2.C3A ZNF385A
Mean 0.57
Standard deviation 0.12
Values 0.49 0.65
[60]
HuH.7 ZNF385A
Mean 1.03
Standard deviation 0.19
Values 1.2 0.96 0.89
[61]
SNU475 ZNF385A
Mean 4.51
Standard deviation 0.36
Values 4.3 4.8
[62]
THLE ZNF385A
Mean 5.33
Standard deviation 0.13
Values 5.2 5.4
[63]
liver ZNF385A
Mean 0.887
Standard deviation 0.63
Values 1.6 0.21 1.2 0.53
[64]
ref_hepatocyte AKT3
Mean 0.387
Standard deviation 0.32
Values 0 0.53 0.83 0.16 0.41
[65]
HepG2 AKT3
Mean 0.238
Standard deviation 0.15
Values 0.34 0.13
[66]
HepG2.C3A AKT3
Mean 0.036
Standard deviation 0.0097
Values 0.029 0.043
[67]
HuH.7 AKT3
Mean 0.0557
Standard deviation 0.031
Values 0.049 0.09 0.028
[68]
SNU475 AKT3
Mean 40.8
Standard deviation 10
Values 48 34
[69]
THLE AKT3
Mean 22.1
Standard deviation 4.4
Values 25 19
[70]
liver AKT3
Mean 6.71
Standard deviation 4.9
Values 2.8 12 2.3 9.4
[71]
ref_hepatocyte TP73
Mean 0.183
Standard deviation 0.15
Values 0.4 0 0.19 0.23 0.098
[72]
HepG2 TP73
Mean 0.666
Standard deviation 0.13
Values 0.57 0.76
[73]
HepG2.C3A TP73
Mean 3.48
Standard deviation 0.49
Values 3.1 3.8
[74]
HuH.7 TP73
Mean 1.58
Standard deviation 0.41
Values 2.1 1.4 1.3
[75]
SNU475 TP73
Mean 0.537
Standard deviation 0.035
Values 0.56 0.51
[76]
THLE TP73
Mean 1.32
Standard deviation 0.075
Values 1.3 1.4
[77]
liver TP73
Mean 0.407
Standard deviation 0.19
Values 0.19 0.47 0.33 0.64
[78]
ref_hepatocyte TP63
Mean 0.0845
Standard deviation 0.17
Values 0 0.026 0.4 0 0
[79]
HepG2 TP63
Mean 0
Standard deviation 0
Values 0 0
[80]
HepG2.C3A TP63
Mean 0
Standard deviation 0
Values 0 0
[81]
HuH.7 TP63
Mean 0.038
Standard deviation 0.033
Values 0 0.058 0.056
[82]
SNU475 TP63
Mean 0.06
Standard deviation 0.059
Values 0.019 0.1
[83]
THLE TP63
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[84]
liver TP63
Mean 0.0431
Standard deviation 0.045
Values 0.024 0.043 0 0.11
[85]
ref_hepatocyte POU4F1
Mean 0.00612
Standard deviation 0.014
Values 0.031 0 0 0 0
[86]
HepG2 POU4F1
Mean 2.53
Standard deviation 0.45
Values 2.8 2.2
[87]
HepG2.C3A POU4F1
Mean 3.49
Standard deviation 0.87
Values 4.1 2.9
[88]
HuH.7 POU4F1
Mean 0.008
Standard deviation 0.0015
Values 0.0082 0.0064 0.0094
[89]
SNU475 POU4F1
Mean 0.0076
Standard deviation 0.011
Values 0 0.015
[90]
THLE POU4F1
Mean 0
Standard deviation 0
Values 0 0
[91]
liver POU4F1
Mean 0.00642
Standard deviation 0.013
Values 0 0 0.026 0
[92]
ref_hepatocyte POU4F2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[93]
HepG2 POU4F2
Mean 0
Standard deviation 0
Values 0 0
[94]
HepG2.C3A POU4F2
Mean 0
Standard deviation 0
Values 0 0
[95]
HuH.7 POU4F2
Mean 0
Standard deviation 0
Values 0 0 0
[96]
SNU475 POU4F2
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[97]
THLE POU4F2
Mean 0
Standard deviation 0
Values 0 0
[98]
liver POU4F2
Mean 0.00357
Standard deviation 0.0071
Values 0 0.014 0 0