REACTOME_REGULATION_OF_TP53_ACTIVITY | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | UBB | Polyubiquitin-B | [1] | -1.72[2] | -2.07[3] | -2.01[4] | -2.29[5] | -1.92[6] | -1.19[7] |
2 | RPS27A | Ubiquitin-40S ribosomal protein S27a | [8] | [9] | [10] | [11] | [12] | [13] | [14] |
3 | UBC | Polyubiquitin-C | [15] | -1.27[16] | -1.32[17] | -1.64[18] | -1.43[19] | -1.54[20] | -0.74[21] |
4 | UBA52 | Ubiquitin-60S ribosomal protein L40 | [22] | 1.16[23] | 0.92[24] | 1.87[25] | -0.04[26] | 0.69[27] | 0.03[28] |
5 | CSNK2B | Casein kinase II subunit beta | [29] | 0.13[30] | -0.18[31] | -0.89[32] | -0.50[33] | -0.86[34] | -0.82[35] |
6 | TAF9 | Transcription initiation factor TFIID subunit 9 | [36] | -0.63[37] | -0.01[38] | -0.58[39] | -0.75[40] | -0.59[41] | -0.48[42] |
7 | AKT1 | RAC-alpha serine/threonine-protein kinase | [43] | 0.56[44] | 0.18[45] | -0.99[46] | 0.44[47] | 0.37[48] | 0.44[49] |
8 | CSNK2A1 | Casein kinase II subunit alpha | [50] | 0.60[51] | 0.32[52] | 0.16[53] | 0.13[54] | -0.32[55] | -1.05[56] |
9 | TAF10 | Transcription initiation factor TFIID subunit 10 | [57] | -1.28[58] | -1.68[59] | -1.22[60] | -1.28[61] | -2.01[62] | -1.94[63] |
10 | SSRP1 | FACT complex subunit SSRP1 | [64] | 1.13[65] | 0.55[66] | 0.76[67] | 0.67[68] | 1.08[69] | -0.86[70] |
11 | PPP2R1A | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isofor | 1.28[71] | 0.96[72] | 0.79[73] | 1.70[74] | 0.94[75] | 0.83[76] | |
12 | PPP2CA | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform | 0.75[77] | 0.70[78] | -0.03[79] | 1.23[80] | 1.26[81] | 0.58[82] | |
13 | TAF7 | Transcription initiation factor TFIID subunit 7 | [83] | 0.36[84] | 0.46[85] | 0.12[86] | 0.37[87] | 0.33[88] | -0.10[89] |
14 | NOC2L | Nucleolar complex protein 2 homolog | [90] | 0.79[91] | 0.57[92] | 0.25[93] | 0.29[94] | 0.37[95] | -0.55[96] |
15 | TAF13 | Transcription initiation factor TFIID subunit 13 | [97] | -2.78[98] | -3.05[99] | -4.07[100] | -2.25[101] | -2.43[102] | -3.54[103] |
16 | PPP2CB | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform | 0.09[104] | -0.40[105] | -0.41[106] | 0.04[107] | -0.16[108] | -0.30[109] | |
17 | RBBP7 | Histone-binding protein RBBP7 | [110] | 0.35[111] | 0.38[112] | -0.03[113] | 1.14[114] | 1.79[115] | 0.02[116] |
18 | RPA2 | Replication protein A 32 kDa subunit | [117] | -0.98[118] | -1.05[119] | -0.58[120] | -0.25[121] | -0.27[122] | -1.72[123] |
19 | PRMT5 | Protein arginine N-methyltransferase 5 | [124] | 1.86[125] | -0.32[126] | 0.21[127] | 0.15[128] | 0.38[129] | -0.65[130] |
20 | TAF15 | TATA-binding protein-associated factor 2N | [131] | 0.62[132] | -0.15[133] | 0.64[134] | 0.65[135] | 0.98[136] | -1.45[137] |
21 | HDAC1 | Histone deacetylase 1 | [138] | 0.99[139] | 0.85[140] | 1.45[141] | 1.14[142] | 0.83[143] | 0.22[144] |
22 | MAPKAP1 | Target of rapamycin complex 2 subunit MAPKAP1 | [145] | 0.47[146] | 0.07[147] | 0.20[148] | 0.57[149] | 0.67[150] | 0.50[151] |
23 | PRKAG1 | 5'-AMP-activated protein kinase subunit gamma-1 | [152] | -0.94[153] | -0.55[154] | -0.52[155] | 0.15[156] | -0.23[157] | -0.97[158] |
24 | CCNG1 | Cyclin-G1 | [159] | 1.28[160] | 2.41[161] | 2.38[162] | 0.24[163] | 0.53[164] | 1.19[165] |
25 | PIN1 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | [166] | -0.56[167] | -0.65[168] | -0.49[169] | -1.17[170] | -0.12[171] | -0.68[172] |
26 | SUPT16H | FACT complex subunit SPT16 | [173] | 2.09[174] | 1.24[175] | 1.90[176] | 1.97[177] | 2.08[178] | 0.63[179] |
27 | BRD7 | Bromodomain-containing protein 7 | [180] | 1.08[181] | 0.89[182] | -0.41[183] | 0.16[184] | -0.03[185] | -1.07[186] |
28 | DAXX | Death domain-associated protein 6 | [187] | 0.65[188] | 0.36[189] | -0.13[190] | 0.64[191] | 0.43[192] | -0.28[193] |
29 | CHD4 | Chromodomain-helicase-DNA-binding protein 4 | [194] | 2.52[195] | 1.90[196] | 1.86[197] | 2.48[198] | 2.25[199] | 2.25[200] |
30 | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isofor | 0.17[201] | 0.90[202] | 0.51[203] | 1.43[204] | 1.15[205] | 0.49[206] | |
31 | USP7 | Ubiquitin carboxyl-terminal hydrolase 7 | [207] | 2.04[208] | 1.69[209] | 0.99[210] | 0.59[211] | 0.88[212] | 1.22[213] |
32 | TAF11 | Transcription initiation factor TFIID subunit 11 | [214] | -0.11[215] | 0.02[216] | -0.79[217] | 0.22[218] | -0.44[219] | -1.25[220] |
33 | SMYD2 | N-lysine methyltransferase SMYD2 | [221] | 0.92[222] | 0.77[223] | -0.38[224] | -0.34[225] | -1.22[226] | -0.31[227] |
34 | PRKAG2 | 5'-AMP-activated protein kinase subunit gamma-2 | [228] | -3.57[229] | -8.83[230] | -2.48[231] | -1.25[232] | -1.20[233] | 0.21[234] |
35 | TAF12 | Transcription initiation factor TFIID subunit 12 | [235] | -1.16[236] | -1.45[237] | -0.52[238] | -0.76[239] | -1.14[240] | -1.00[241] |
36 | STK11 | Serine/threonine-protein kinase STK11 | [242] | 0.40[243] | 0.19[244] | 0.35[245] | -0.22[246] | 0.05[247] | -0.18[248] |
37 | MTA2 | Metastasis-associated protein MTA2 | [249] | 1.50[250] | 0.52[251] | 0.78[252] | 1.12[253] | 1.26[254] | 0.25[255] |
38 | CDK2 | Cyclin-dependent kinase 2 | [256] | 0.07[257] | 0.08[258] | 0.37[259] | 0.47[260] | 0.97[261] | -1.50[262] |
39 | PPP2R1B | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform | 0.93[263] | 0.26[264] | 0.58[265] | 0.76[266] | 0.45[267] | 3.61[268] | |
40 | MBD3 | Methyl-CpG-binding domain protein 3 | [269] | 0.95[270] | 1.37[271] | 0.45[272] | 0.18[273] | 1.08[274] | 0.59[275] |
41 | RFC4 | Replication factor C subunit 4 | [276] | -0.49[277] | -0.01[278] | 0.48[279] | -0.48[280] | 0.77[281] | -2.07[282] |
42 | AKT2 | RAC-beta serine/threonine-protein kinase | [283] | 1.44[284] | 1.57[285] | 1.60[286] | 1.35[287] | 1.05[288] | 1.81[289] |
43 | MLST8 | Target of rapamycin complex subunit LST8 | [290] | 0.31[291] | 0.49[292] | 0.77[293] | -0.48[294] | -0.23[295] | 0.12[296] |
44 | MEAF6 | Chromatin modification-related protein MEAF6 | [297] | 0.98[298] | 1.01[299] | -0.36[300] | 0.52[301] | 0.16[302] | 0.18[303] |
45 | SGK1 | Serine/threonine-protein kinase Sgk1 | [304] | -0.57[305] | -1.68[306] | 2.29[307] | 0.11[308] | 1.66[309] | 1.77[310] |
46 | MAPKAPK | MAP kinase-activated protein kinase 5 | [311] | -0.35[312] | 0.35[313] | 0.20[314] | -0.71[315] | -0.56[316] | -0.27[317] |
47 | RFC2 | Replication factor C subunit 2 | [318] | 0.22[319] | -0.08[320] | -0.12[321] | 0.67[322] | 1.04[323] | -0.09[324] |
48 | RFFL | E3 ubiquitin-protein ligase rififylin | [325] | -1.33[326] | -1.20[327] | -0.59[328] | -1.91[329] | -2.96[330] | -0.78[331] |
49 | MAPK14 | Mitogen-activated protein kinase 14 | [332] | 1.96[333] | 1.88[334] | 1.36[335] | 2.18[336] | 1.56[337] | 1.97[338] |
50 | RNF34 | E3 ubiquitin-protein ligase RNF34 | [339] | 0.45[340] | 0.14[341] | -0.49[342] | -0.10[343] | 0.19[344] | 0.18[345] |
51 | RPA1 | Replication protein A 70 kDa DNA-binding subunit | [346] | 1.79[347] | 1.38[348] | 1.56[349] | 2.34[350] | 2.27[351] | 0.68[352] |
52 | RPA3 | Replication protein A 14 kDa subunit | [353] | 0.11[354] | 0.77[355] | 1.40[356] | -0.41[357] | -0.22[358] | -0.01[359] |
53 | GATAD2A | Transcriptional repressor p66-alpha | [360] | 1.64[361] | 0.69[362] | 1.96[363] | 0.77[364] | 1.55[365] | 0.74[366] |
54 | PRKAA1 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | [367] | 0.40[368] | 1.53[369] | 2.95[370] | 1.96[371] | 2.14[372] | 2.74[373] |
55 | TP53INP1 | Tumor protein p53-inducible nuclear protein 1 | [374] | 0.84[375] | 0.93[376] | 0.09[377] | 0.70[378] | -0.31[379] | 3.70[380] |
56 | CSNK2A2 | Casein kinase II subunit alpha' | [381] | 0.68[382] | 0.59[383] | 0.50[384] | 0.08[385] | 0.19[386] | -1.52[387] |
57 | PRKAB2 | 5'-AMP-activated protein kinase subunit beta-2 | [388] | 1.37[389] | 2.40[390] | 2.42[391] | 1.52[392] | 0.40[393] | 2.09[394] |
58 | PRR5 | Proline-rich protein 5 | [395] | -0.11[396] | -0.20[397] | -1.21[398] | -1.79[399] | -4.68[400] | -0.10[401] |
59 | AURKA | Aurora kinase A | [402] | 2.19[403] | 2.30[404] | 1.71[405] | 2.11[406] | 1.93[407] | -2.12[408] |
60 | RBBP4 | Histone-binding protein RBBP4 | [409] | 2.42[410] | 2.39[411] | 2.11[412] | 2.17[413] | 2.47[414] | 2.18[415] |
61 | RAD17 | Cell cycle checkpoint protein RAD17 | [416] | -0.37[417] | 0.57[418] | 0.53[419] | 0.15[420] | 0.41[421] | 0.25[422] |
62 | KAT5 | Histone acetyltransferase KAT5 | [423] | -0.30[424] | -0.03[425] | -1.16[426] | -0.34[427] | -0.52[428] | -0.39[429] |
63 | HDAC2 | Histone deacetylase 2 | [430] | 2.21[431] | 3.38[432] | 2.66[433] | 2.65[434] | 2.70[435] | 0.88[436] |
64 | MDM2 | E3 ubiquitin-protein ligase Mdm2 | [437] | 2.59[438] | 3.86[439] | 1.01[440] | 1.00[441] | 1.79[442] | 2.85[443] |
65 | TP53BP2 | Apoptosis-stimulating of p53 protein 2 | [444] | -0.12[445] | 0.06[446] | 1.55[447] | 1.75[448] | 0.95[449] | 0.74[450] |
66 | NBN | Nibrin | [451] | 0.06[452] | 1.09[453] | 0.76[454] | 2.00[455] | 1.03[456] | 1.95[457] |
67 | TBP | TATA-box-binding protein | [458] | 0.26[459] | 0.40[460] | -0.87[461] | -0.59[462] | 0.11[463] | -0.39[464] |
68 | CDK1 | Cyclin-dependent kinase 1 | [465] | 1.73[466] | 3.65[467] | 2.29[468] | 2.76[469] | 3.49[470] | -1.79[471] |
69 | CHEK2 | Serine/threonine-protein kinase Chk2 | [472] | 0.58[473] | 0.87[474] | 1.18[475] | 0.24[476] | -0.22[477] | -2.60[478] |
70 | TAF6 | Transcription initiation factor TFIID subunit 6 | [479] | 1.43[480] | 0.84[481] | 1.27[482] | 1.31[483] | 1.59[484] | 0.53[485] |
71 | RFC5 | Replication factor C subunit 5 | [486] | 0.61[487] | 0.92[488] | 1.03[489] | 0.76[490] | 1.20[491] | -0.20[492] |
72 | AURKB | Aurora kinase B | [493] | 1.07[494] | 1.28[495] | 2.22[496] | 0.83[497] | 1.28[498] | -2.67[499] |
73 | TP53 | Cellular tumor antigen p53 | [500] | 2.12[501] | 1.53[502] | 2.20[503] | 1.79[504] | 1.36[505] | 0.64[506] |
74 | PIP4K2C | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma | [507] | 1.77[508] | 1.55[509] | 0.81[510] | 1.06[511] | 0.93[512] | 0.63[513] |
75 | PRKAB1 | 5'-AMP-activated protein kinase subunit beta-1 | [514] | 1.19[515] | 1.58[516] | 0.63[517] | 0.43[518] | 0.44[519] | 0.68[520] |
76 | TP53RK | TP53-regulating kinase | [521] | 1.70[522] | 1.55[523] | -0.55[524] | 0.96[525] | 0.63[526] | 0.60[527] |
77 | CDK5 | Cyclin-dependent-like kinase 5 | [528] | 0.72[529] | -0.12[530] | -0.16[531] | 1.12[532] | -0.18[533] | -0.20[534] |
78 | TPX2 | Targeting protein for Xklp2 | [535] | 3.75[536] | 3.52[537] | 4.42[538] | 3.89[539] | 3.88[540] | -0.55[541] |
79 | ING2 | Inhibitor of growth protein 2 | [542] | -1.37[543] | -1.31[544] | -2.07[545] | -1.36[546] | -1.10[547] | -1.63[548] |
80 | HIPK2 | Homeodomain-interacting protein kinase 2 | [549] | 2.48[550] | 2.65[551] | 1.90[552] | 3.22[553] | 3.24[554] | 5.12[555] |
81 | EHMT2 | Histone-lysine N-methyltransferase EHMT2 | [556] | 2.96[557] | 2.42[558] | 2.40[559] | 3.15[560] | 1.78[561] | 0.94[562] |
82 | RAD50 | DNA repair protein RAD50 | [563] | 0.63[564] | 2.62[565] | 1.68[566] | 1.76[567] | 2.16[568] | 2.89[569] |
83 | RMI2 | RecQ-mediated genome instability protein 2 | [570] | 1.73[571] | 0.87[572] | 0.73[573] | -0.71[574] | -0.49[575] | -3.75[576] |
84 | BRPF3 | Bromodomain and PHD finger-containing protein 3 | [577] | 2.68[578] | 2.05[579] | 1.33[580] | 2.30[581] | 1.95[582] | 1.99[583] |
85 | PML | Protein PML | [584] | 0.72[585] | -0.44[586] | 1.17[587] | 2.38[588] | 1.78[589] | 0.92[590] |
86 | PIP4K2B | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | [591] | 3.01[592] | 2.44[593] | 2.62[594] | 2.94[595] | 2.14[596] | 1.84[597] |
87 | RBBP8 | DNA endonuclease RBBP8 | [598] | 0.68[599] | 1.94[600] | 0.48[601] | 1.93[602] | 2.04[603] | 0.93[604] |
88 | BANP | Protein BANP | [605] | 0.02[606] | 1.01[607] | -0.02[608] | 0.11[609] | -0.31[610] | 1.08[611] |
89 | HIPK1 | Homeodomain-interacting protein kinase 1 | [612] | 2.05[613] | 1.93[614] | 2.78[615] | 2.70[616] | 2.46[617] | 2.93[618] |
90 | TAF9B | Transcription initiation factor TFIID subunit 9B | [619] | 0.44[620] | 1.28[621] | 1.19[622] | 1.71[623] | 1.64[624] | 1.36[625] |
91 | PDPK1 | 3-phosphoinositide-dependent protein kinase 1 | [626] | 2.81[627] | 3.85[628] | 2.47[629] | 1.93[630] | 2.23[631] | 3.19[632] |
92 | TOPBP1 | DNA topoisomerase 2-binding protein 1 | [633] | 1.51[634] | 2.39[635] | 2.45[636] | 2.62[637] | 2.94[638] | 1.56[639] |
93 | MTOR | Serine/threonine-protein kinase mTOR | [640] | 3.01[641] | 3.88[642] | 3.35[643] | 3.18[644] | 3.16[645] | 4.13[646] |
94 | PIP4K2A | Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha | [647] | 2.12[648] | 1.24[649] | 1.21[650] | 2.75[651] | 1.61[652] | 1.98[653] |
95 | CCNA2 | Cyclin-A2 | [654] | 2.69[655] | 3.55[656] | 2.80[657] | 2.50[658] | 3.79[659] | -0.55[660] |
96 | EHMT1 | Histone-lysine N-methyltransferase EHMT1 | [661] | 2.12[662] | 1.77[663] | 2.00[664] | 2.18[665] | 1.70[666] | 2.59[667] |
97 | RFC3 | Replication factor C subunit 3 | [668] | 1.66[669] | 2.37[670] | 2.42[671] | 1.74[672] | 2.25[673] | -0.19[674] |
98 | HUS1 | Checkpoint protein HUS1 | [675] | -0.24[676] | -0.11[677] | 0.34[678] | 0.38[679] | 0.09[680] | 2.05[681] |
99 | PPP1R13L | RelA-associated inhibitor | [682] | 0.88[683] | -0.04[684] | 1.60[685] | 1.83[686] | 1.03[687] | -1.11[688] |
100 | TAF4 | Transcription initiation factor TFIID subunit 4 | [689] | 1.89[690] | 1.34[691] | 1.02[692] | 1.25[693] | 0.20[694] | 0.31[695] |
101 | TAF2 | Transcription initiation factor TFIID subunit 2 | [696] | 1.08[697] | 1.62[698] | 2.00[699] | 2.46[700] | 2.23[701] | 2.60[702] |
102 | SETD9 | SET domain-containing protein 9 | [703] | -1.07[704] | -0.10[705] | -1.44[706] | -0.68[707] | -1.35[708] | 0.24[709] |
103 | BRD1 | Bromodomain-containing protein 1 | [710] | 1.76[711] | 1.59[712] | 2.54[713] | 0.99[714] | 1.59[715] | 2.14[716] |
104 | EP300 | Histone acetyltransferase p300 | [717] | 3.20[718] | 2.65[719] | 3.45[720] | 3.06[721] | 3.02[722] | 3.44[723] |
105 | CHEK1 | Serine/threonine-protein kinase Chk1 | [724] | 2.02[725] | 2.23[726] | 1.71[727] | 2.64[728] | 2.78[729] | -1.35[730] |
106 | PLK3 | Serine/threonine-protein kinase PLK3 | [731] | 1.18[732] | 0.91[733] | -2.23[734] | -0.43[735] | 0.70[736] | -0.62[737] |
107 | TAF3 | Transcription initiation factor TFIID subunit 3 | [738] | 0.61[739] | 0.19[740] | 0.49[741] | 1.17[742] | 0.95[743] | 1.07[744] |
108 | PHF20 | PHD finger protein 20 | [745] | 2.61[746] | 2.25[747] | 2.71[748] | 3.70[749] | 2.63[750] | 2.44[751] |
109 | TOP3A | DNA topoisomerase 3-alpha | [752] | 2.45[753] | 1.97[754] | 2.18[755] | 2.34[756] | 2.64[757] | 2.48[758] |
110 | RAD1 | Cell cycle checkpoint protein RAD1 | [759] | 1.85[760] | 2.38[761] | 2.82[762] | 2.30[763] | 3.10[764] | 1.59[765] |
111 | ING5 | Inhibitor of growth protein 5 | [766] | 2.06[767] | 2.76[768] | 1.38[769] | 1.10[770] | 0.91[771] | 1.63[772] |
112 | KAT6A | Histone acetyltransferase KAT6A | [773] | 2.45[774] | 2.38[775] | 3.35[776] | 2.53[777] | 2.45[778] | 3.77[779] |
113 | PPP1R13B | Apoptosis-stimulating of p53 protein 1 | [780] | 2.02[781] | 1.17[782] | 0.16[783] | 1.44[784] | 1.20[785] | 1.67[786] |
114 | RAD9A | Cell cycle checkpoint control protein RAD9A | [787] | 0.55[788] | 0.69[789] | 2.40[790] | 2.82[791] | 0.56[792] | 0.51[793] |
115 | BRCA1 | Breast cancer type 1 susceptibility protein | [794] | 2.15[795] | 3.25[796] | 3.55[797] | 2.64[798] | 3.07[799] | 2.36[800] |
116 | TTC5 | Tetratricopeptide repeat protein 5 | [801] | 1.76[802] | 0.65[803] | 0.38[804] | 1.02[805] | 0.98[806] | 0.96[807] |
117 | RICTOR | Rapamycin-insensitive companion of mTOR | [808] | 1.21[809] | 3.14[810] | 3.72[811] | 2.85[812] | 2.96[813] | 4.20[814] |
118 | MAP2K6 | Dual specificity mitogen-activated protein kinase kinase 6 | [815] | 0.77[816] | -2.59[817] | 2.17[818] | 1.50[819] | -2.62[820] | -0.94[821] |
119 | ATRIP | ATR-interacting protein | [822] | 0.73[823] | 0.82[824] | 1.60[825] | 0.15[826] | 1.13[827] | 0.52[828] |
120 | ATR | Serine/threonine-protein kinase ATR | [829] | 1.58[830] | 2.42[831] | 2.41[832] | 3.02[833] | 2.89[834] | 4.23[835] |
121 | DYRK2 | Dual specificity tyrosine-phosphorylation-regulated kinase 2 | [836] | 1.65[837] | 1.85[838] | 3.27[839] | 3.25[840] | 2.13[841] | 2.74[842] |
122 | GATAD2B | Transcriptional repressor p66-beta | [843] | 2.12[844] | 1.59[845] | 2.92[846] | 3.27[847] | 2.98[848] | 2.80[849] |
123 | WRN | Werner syndrome ATP-dependent helicase | [850] | 1.09[851] | 2.40[852] | 4.25[853] | 2.19[854] | 1.91[855] | 2.65[856] |
124 | TAF1 | Transcription initiation factor TFIID subunit 1 | [857] | 2.43[858] | 2.80[859] | 2.07[860] | 3.61[861] | 2.81[862] | 3.83[863] |
125 | USP2 | Ubiquitin carboxyl-terminal hydrolase 2 | [864] | 1.70[865] | 1.21[866] | 0.15[867] | 0.20[868] | -1.39[869] | 0.81[870] |
126 | BRPF1 | Peregrin | [871] | 2.59[872] | 2.08[873] | 3.09[874] | 2.46[875] | 3.04[876] | 2.29[877] |
127 | RMI1 | RecQ-mediated genome instability protein 1 | [878] | 1.06[879] | 2.15[880] | 2.51[881] | 2.57[882] | 3.32[883] | 1.67[884] |
128 | JMY | Junction-mediating and -regulatory protein | [885] | 1.73[886] | 2.65[887] | 3.34[888] | 2.62[889] | 2.87[890] | 4.09[891] |
129 | TAF5 | Transcription initiation factor TFIID subunit 5 | [892] | 0.71[893] | 1.59[894] | 2.90[895] | 0.39[896] | 1.60[897] | 1.09[898] |
130 | ATM | Serine-protein kinase ATM | [899] | 3.51[900] | 4.97[901] | 4.60[902] | 4.65[903] | 4.04[904] | 5.67[905] |
131 | MDM4 | Protein Mdm4 | [906] | 2.12[907] | 2.98[908] | 3.33[909] | 2.79[910] | 2.58[911] | 5.24[912] |
132 | ZNF385A | Zinc finger protein 385A | [913] | 2.03[914] | -1.17[915] | -0.34[916] | 2.08[917] | 2.06[918] | 0.29[919] |
133 | PRKAA2 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | [920] | 3.51[921] | 3.81[922] | 3.75[923] | 3.54[924] | 1.49[925] | 2.53[926] |
134 | CHD3 | Chromodomain-helicase-DNA-binding protein 3 | [927] | 3.28[928] | 3.74[929] | 5.77[930] | 6.79[931] | 5.87[932] | 3.20[933] |
135 | DNA2 | DNA replication ATP-dependent helicase/nuclease DNA2 | [934] | 2.24[935] | 3.86[936] | 2.97[937] | 3.14[938] | 2.71[939] | 2.24[940] |
136 | EXO1 | Exonuclease 1 | [941] | 2.39[942] | 2.52[943] | 3.60[944] | 4.27[945] | 3.46[946] | -0.79[947] |
137 | NUAK1 | NUAK family SNF1-like kinase 1 | [948] | 3.13[949] | -1.07[950] | 2.95[951] | 3.72[952] | 2.79[953] | 4.15[954] |
138 | BRIP1 | Fanconi anemia group J protein | [955] | 2.63[956] | 3.88[957] | 3.80[958] | 3.70[959] | 3.65[960] | 2.64[961] |
139 | BLM | Bloom syndrome protein | [962] | 2.02[963] | 3.23[964] | 3.95[965] | 3.39[966] | 3.37[967] | 0.30[968] |
140 | BARD1 | BRCA1-associated RING domain protein 1 | [969] | 1.79[970] | 2.63[971] | 2.57[972] | 3.19[973] | 3.18[974] | 2.55[975] |
141 | AKT3 | RAC-gamma serine/threonine-protein kinase | [976] | -1.36[977] | -4.07[978] | -3.47[979] | 6.34[980] | 5.20[981] | 4.29[982] |
142 | MAPK11 | Mitogen-activated protein kinase 11 | [983] | 0.31[984] | 0.06[985] | -0.92[986] | 0.85[987] | 2.75[988] | 0.85[989] |
143 | CDK5R1 | Cyclin-dependent kinase 5 activator 1 | [990] | 2.57[991] | 2.19[992] | 2.26[993] | 2.47[994] | 1.74[995] | 0.31[996] |
144 | CDKN2A | Cyclin-dependent kinase inhibitor 2A | [997] | 4.56[998] | 2.18[999] | 5.50[1000] | 5.70[1001] | 7.39[1002] | -1.47[1003] |
145 | TP73 | Tumor protein p73 | [1004] | 1.21[1005] | 3.61[1006] | 2.44[1007] | 1.17[1008] | 2.21[1009] | 1.33[1010] |
146 | L3MBTL1 | Lethal(3)malignant brain tumor-like protein 1 | [1011] | 2.51[1012] | 4.31[1013] | 1.87[1014] | 2.08[1015] | 1.53[1016] | 2.87[1017] |
147 | TAF4B | Transcription initiation factor TFIID subunit 4B | [1018] | 2.50[1019] | 2.74[1020] | [1021] | 3.49[1022] | 3.77[1023] | 1.58[1024] |
148 | RAD9B | Cell cycle checkpoint control protein RAD9B | [1025] | -2.85[1026] | 0.20[1027] | -0.58[1028] | 0.92[1029] | 0.17[1030] | -0.11[1031] |
149 | PRDM1 | PR domain zinc finger protein 1 | [1032] | -3.33[1033] | -5.31[1034] | 1.68[1035] | 3.85[1036] | 1.44[1037] | 4.05[1038] |
150 | TP63 | Tumor protein 63 | [1039] | [1040] | [1041] | -1.83[1042] | -0.88[1043] | -4.55[1044] | -0.80[1045] |
151 | TAF7L | Transcription initiation factor TFIID subunit 7-like | [1046] | -5.45[1047] | -4.25[1048] | -1.66[1049] | -1.66[1050] | -1.24[1051] | 2.42[1052] |
152 | TAF1L | Transcription initiation factor TFIID subunit 1-like | [1053] | -1.25[1054] | -0.57[1055] | -2.33[1056] | -0.28[1057] | -1.59[1058] | -0.52[1059] |
153 | CCNA1 | Cyclin-A1 | [1060] | [1061] | -3.06[1062] | [1063] | -0.30[1064] | 7.02[1065] | [1066] |
154 | PRKAG3 | 5'-AMP-activated protein kinase subunit gamma-3 | [1067] | -1.26[1068] | [1069] | -1.83[1070] | -0.52[1071] | [1072] | 3.81[1073] |
155 | POU4F1 | POU domain, class 4, transcription factor 1 | [1074] | 8.03[1075] | 8.51[1076] | -0.29[1077] | -0.07[1078] | [1079] | 0.25[1080] |
156 | RHNO1 | RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 | [1081] | [1082] | [1083] | [1084] | [1085] | [1086] | [1087] |
157 | POU4F2 | POU domain, class 4, transcription factor 2 | [1088] | [1089] | [1090] | [1091] | [1092] | [1093] | [1094] |
158 | KMT5A | N-lysine methyltransferase KMT5A | [1095] | [1096] | [1097] | [1098] | [1099] | [1100] | [1101] |
159 | MRE11 | Double-strand break repair protein MRE11 | [1102] | [1103] | [1104] | [1105] | [1106] | [1107] | [1108] |
160 | PIP4P1 | Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase | [1109] | [1110] | [1111] | [1112] | [1113] | [1114] | [1115] |