REACTOME_REGULATION_OF_TNFR1_SIGNALING			Return to index
Order	Gene	Description	ref_hepatocyte	HepG2	HepG2.C3A	HuH.7	SNU475	THLE	liver
1	UBB	Polyubiquitin-B	[1]	-0.57[2]	-0.89[3]	-0.74[4]	-0.99[5]	-0.66[6]	-0.42[7]
2	RPS27A	Ubiquitin-40S ribosomal protein S27a	[8]	[9]	[10]	[11]	[12]	[13]	[14]
3	UBC	Polyubiquitin-C	[15]	-0.13[16]	-0.14[17]	-0.37[18]	-0.13[19]	-0.29[20]	0.03[21]
4	UBA52	Ubiquitin-60S ribosomal protein L40	[22]	2.31[23]	2.09[24]	3.14[25]	1.26[26]	1.94[27]	0.80[28]
5	TNFRSF1A	Tumor necrosis factor receptor superfamily member 1A	[29]	1.16[30]	0.57[31]	0.87[32]	2.16[33]	2.20[34]	1.53[35]
6	SPPL2A	Signal peptide peptidase-like 2A	[36]	-0.17[37]	0.11[38]	-0.10[39]	1.75[40]	0.56[41]	1.72[42]
7	IKBKG	NF-kappa-B essential modulator	[43]	0.74[44]	0.76[45]	-1.48[46]	0.94[47]	-0.41[48]	0.85[49]
8	TAX1BP1	Tax1-binding protein 1	[50]	1.53[51]	2.58[52]	2.77[53]	2.77[54]	1.84[55]	2.01[56]
9	RBCK1	RanBP-type and C3HC4-type zinc finger-containing protein 1	[57]	2.54[58]	3.07[59]	1.21[60]	1.57[61]	0.81[62]	0.99[63]
10	CFLAR	CASP8 and FADD-like apoptosis regulator	[64]	1.24[65]	1.86[66]	1.42[67]	1.25[68]	1.27[69]	3.02[70]
11	BIRC3	Baculoviral IAP repeat-containing protein 3	[71]	-1.49[72]	-0.59[73]	-2.98[74]	-1.33[75]	2.30[76]	-0.62[77]
12	TNFAIP3	Tumor necrosis factor alpha-induced protein 3	[78]	2.26[79]	2.83[80]	-0.42[81]	0.58[82]	2.41[83]	0.42[84]
13	BIRC2	Baculoviral IAP repeat-containing protein 2	[85]	1.87[86]	2.70[87]	1.66[88]	2.21[89]	2.86[90]	2.18[91]
14	SHARPIN	Sharpin	[92]	1.36[93]	1.08[94]	1.12[95]	1.88[96]	1.22[97]	1.16[98]
15	FADD	FAS-associated death domain protein	[99]	1.67[100]	0.83[101]	1.56[102]	3.73[103]	1.40[104]	-0.32[105]
16	CASP8	Caspase-8	[106]	1.65[107]	2.09[108]	1.27[109]	1.71[110]	0.83[111]	0.03[112]
17	TRAF1	TNF receptor-associated factor 1	[113]	-2.80[114]	-3.05[115]	-2.20[116]	-1.74[117]	-1.32[118]	-1.44[119]
18	TRADD	Tumor necrosis factor receptor type 1-associated DEATH domain protein		1.37[120]	1.08[121]	-0.08[122]	0.81[123]	0.52[124]	0.87[125]
19	USP4	Ubiquitin carboxyl-terminal hydrolase 4	[126]	1.81[127]	2.17[128]	1.43[129]	1.80[130]	2.65[131]	2.27[132]
20	TRAF2	TNF receptor-associated factor 2	[133]	1.86[134]	1.79[135]	1.53[136]	1.92[137]	1.79[138]	0.66[139]
21	RIPK1	Receptor-interacting serine/threonine-protein kinase 1	[140]	1.91[141]	1.95[142]	1.64[143]	2.87[144]	2.26[145]	2.94[146]
22	CYLD	Ubiquitin carboxyl-terminal hydrolase CYLD	[147]	1.52[148]	1.53[149]	0.35[150]	2.74[151]	3.83[152]	3.39[153]
23	RNF31	E3 ubiquitin-protein ligase RNF31	[154]	4.07[155]	2.16[156]	2.96[157]	2.91[158]	2.37[159]	2.54[160]
24	CHUK	Inhibitor of nuclear factor kappa-B kinase subunit alpha	[161]	2.53[162]	3.63[163]	3.59[164]	2.44[165]	3.12[166]	2.97[167]
25	IKBKB	Inhibitor of nuclear factor kappa-B kinase subunit beta	[168]	2.15[169]	2.08[170]	2.19[171]	2.05[172]	2.01[173]	2.64[174]
26	OTUD7B	OTU domain-containing protein 7B	[175]	2.70[176]	2.15[177]	2.56[178]	3.88[179]	3.19[180]	2.87[181]
27	XIAP	E3 ubiquitin-protein ligase XIAP	[182]	3.14[183]	3.61[184]	4.07[185]	4.39[186]	3.67[187]	4.14[188]
28	SPPL2B	Signal peptide peptidase-like 2B	[189]	2.91[190]	3.04[191]	3.48[192]	2.27[193]	2.86[194]	2.69[195]
29	USP21	Ubiquitin carboxyl-terminal hydrolase 21	[196]	2.69[197]	2.72[198]	2.64[199]	3.31[200]	2.88[201]	1.49[202]
30	MADD	MAP kinase-activating death domain protein	[203]	4.18[204]	3.92[205]	4.35[206]	3.88[207]	3.44[208]	4.02[209]
31	USP2	Ubiquitin carboxyl-terminal hydrolase 2	[210]	2.84[211]	2.39[212]	1.42[213]	1.51[214]	-0.13[215]	1.58[216]
32	CLIP3	CAP-Gly domain-containing linker protein 3	[217]	1.81[218]	2.88[219]	2.97[220]	2.85[221]	7.07[222]	2.57[223]
33	TNF	Tumor necrosis factor	[224]	2.73[225]	0.47[226]	-4.12[227]	-0.43[228]	-3.79[229]	-0.44[230]
34	OTULIN	Ubiquitin thioesterase otulin	[231]	[232]	[233]	[234]	[235]	[236]	[237]
35	RACK1	Receptor of activated protein C kinase 1	[238]	[239]	[240]	[241]	[242]	[243]	[244]