REACTOME_REGULATION_OF_SIGNALING_BY_NODAL Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 ACVR1B Activin receptor type-1B [1] -0.03[2] -0.62[3] -0.03[4] 0.41[5] 0.47[6] -0.53[7]
2 TDGF1 Teratocarcinoma-derived growth factor 1 [8] -1.49[9] -7.80[10] -7.48[11] -9.60[12] -9.14[13] -2.69[14]
3 ACVR2A Activin receptor type-2A [15] 0.13[16] 0.60[17] -0.90[18] 0.15[19] 0.40[20] 1.13[21]
4 ACVR2B Activin receptor type-2B [22] 1.56[23] 2.41[24] 1.90[25] 0.43[26] -0.03[27] 1.62[28]
5 DAND5 DAN domain family member 5 [29] -2.78[30] -2.51[31] -4.16[32] -1.22[33] -2.83[34] -3.97[35]
6 LEFTY1 Left-right determination factor 1 [36] -1.26[37] -3.28[38] -3.38[39] -5.23[40] -5.43[41] -2.48[42]
7 ACVR1C Activin receptor type-1C [43] -2.00[44] -1.56[45] 2.34[46] -1.71[47] -2.87[48] 2.24[49]
8 LEFTY2 Left-right determination factor 2 [50] -0.46[51] -1.20[52] 0.46[53] -0.48[54] -5.30[55] -3.57[56]
9 NODAL Nodal homolog [57] 3.18[58] -1.08[59] 2.40[60] 2.90[61] 1.35[62] 3.13[63]
10 CER1 Cerberus [64] [65] [66] [67] [68] [69] [70]
11 TDGF1P3 Putative teratocarcinoma-derived growth factor 3 [71] [72] [73] [74] [75] [76] [77]
12 CFC1 Cryptic protein [78] [79] [80] [81] [82] [83] [84]
[1]
ref_hepatocyte ACVR1B
Mean 4.32
Standard deviation 1.8
Values 1.8 3.4 5.3 6.3 4.8
[2]
HepG2 ACVR1B
Mean 15.4
Standard deviation 2.5
Values 17 14
[3]
HepG2.C3A ACVR1B
Mean 13.3
Standard deviation 0.78
Values 14 13
[4]
HuH.7 ACVR1B
Mean 48.4
Standard deviation 11
Values 59 37 49
[5]
SNU475 ACVR1B
Mean 16.8
Standard deviation 1.8
Values 18 16
[6]
THLE ACVR1B
Mean 23.4
Standard deviation 6.1
Values 19 28
[7]
liver ACVR1B
Mean 12.4
Standard deviation 7.1
Values 7.6 19 5.1 18
[8]
ref_hepatocyte TDGF1
Mean 1.24
Standard deviation 1.2
Values 0.8 0.067 3.3 0.78 1.3
[9]
HepG2 TDGF1
Mean 1.6
Standard deviation 0.22
Values 1.4 1.8
[10]
HepG2.C3A TDGF1
Mean 0.0263
Standard deviation 0.023
Values 0.0097 0.043
[11]
HuH.7 TDGF1
Mean 0.0792
Standard deviation 0.049
Values 0.09 0.026 0.12
[12]
SNU475 TDGF1
Mean 0.00464
Standard deviation 0.0066
Values 0.0093 0
[13]
THLE TDGF1
Mean 0.00858
Standard deviation 0.0046
Values 0.012 0.0053
[14]
liver TDGF1
Mean 0.794
Standard deviation 0.53
Values 1.5 0.37 0.98 0.37
[15]
ref_hepatocyte ACVR2A
Mean 0.936
Standard deviation 0.37
Values 1.1 0.98 0.3 1.1 1.2
[16]
HepG2 ACVR2A
Mean 3.74
Standard deviation 1
Values 3 4.5
[17]
HepG2.C3A ACVR2A
Mean 6.72
Standard deviation 1.6
Values 7.9 5.6
[18]
HuH.7 ACVR2A
Mean 5.74
Standard deviation 0.84
Values 5.9 6.5 4.8
[19]
SNU475 ACVR2A
Mean 3.04
Standard deviation 0.25
Values 2.9 3.2
[20]
THLE ACVR2A
Mean 4.84
Standard deviation 0.58
Values 5.2 4.4
[21]
liver ACVR2A
Mean 8.52
Standard deviation 0.53
Values 7.8 8.6 9.1 8.6
[22]
ref_hepatocyte ACVR2B
Mean 0.673
Standard deviation 0.59
Values 1.7 0.32 0.36 0.37 0.62
[23]
HepG2 ACVR2B
Mean 7.22
Standard deviation 2
Values 8.6 5.8
[24]
HepG2.C3A ACVR2B
Mean 16.9
Standard deviation 7.7
Values 22 12
[25]
HuH.7 ACVR2B
Mean 28.7
Standard deviation 6.3
Values 32 33 21
[26]
SNU475 ACVR2B
Mean 2.64
Standard deviation 0.036
Values 2.6 2.7
[27]
THLE ACVR2B
Mean 2.58
Standard deviation 0.1
Values 2.5 2.6
[28]
liver ACVR2B
Mean 8.61
Standard deviation 5.5
Values 4.7 11 3.4 15
[29]
ref_hepatocyte DAND5
Mean 0.398
Standard deviation 0.19
Values 0.56 0.63 0.29 0.3 0.2
[30]
HepG2 DAND5
Mean 0.211
Standard deviation 0.026
Values 0.23 0.19
[31]
HepG2.C3A DAND5
Mean 0.332
Standard deviation 0.14
Values 0.43 0.24
[32]
HuH.7 DAND5
Mean 0.255
Standard deviation 0.095
Values 0.15 0.29 0.33
[33]
SNU475 DAND5
Mean 0.497
Standard deviation 0.12
Values 0.58 0.41
[34]
THLE DAND5
Mean 0.218
Standard deviation 0.14
Values 0.32 0.12
[35]
liver DAND5
Mean 0.105
Standard deviation 0.084
Values 0 0.19 0.077 0.16
[36]
ref_hepatocyte LEFTY1
Mean 0.255
Standard deviation 0.27
Values 0.36 0 0.68 0.086 0.15
[37]
HepG2 LEFTY1
Mean 0.387
Standard deviation 0.31
Values 0.61 0.17
[38]
HepG2.C3A LEFTY1
Mean 0.124
Standard deviation 0.052
Values 0.087 0.16
[39]
HuH.7 LEFTY1
Mean 0.28
Standard deviation 0.12
Values 0.35 0.14 0.35
[40]
SNU475 LEFTY1
Mean 0.0198
Standard deviation 0.015
Values 0.0093 0.03
[41]
THLE LEFTY1
Mean 0.0231
Standard deviation 0.018
Values 0.035 0.011
[42]
liver LEFTY1
Mean 0.19
Standard deviation 0.11
Values 0.26 0.057 0.15 0.29
[43]
ref_hepatocyte ACVR1C
Mean 0.114
Standard deviation 0.13
Values 0 0.17 0 0.086 0.31
[44]
HepG2 ACVR1C
Mean 0.104
Standard deviation 0.11
Values 0.023 0.18
[45]
HepG2.C3A ACVR1C
Mean 0.183
Standard deviation 0.14
Values 0.087 0.28
[46]
HuH.7 ACVR1C
Mean 6.57
Standard deviation 0.82
Values 7 7.1 5.6
[47]
SNU475 ACVR1C
Mean 0.101
Standard deviation 0.0073
Values 0.11 0.096
[48]
THLE ACVR1C
Mean 0.0606
Standard deviation 0.048
Values 0.095 0.027
[49]
liver ACVR1C
Mean 2.23
Standard deviation 0.55
Values 2.9 2.3 1.6 2.1
[50]
ref_hepatocyte LEFTY2
Mean 0.0598
Standard deviation 0.13
Values 0 0 0.3 0 0
[51]
HepG2 LEFTY2
Mean 0.158
Standard deviation 0.18
Values 0.29 0.03
[52]
HepG2.C3A LEFTY2
Mean 0.123
Standard deviation 0.023
Values 0.11 0.14
[53]
HuH.7 LEFTY2
Mean 0.94
Standard deviation 0.51
Values 0.76 0.54 1.5
[54]
SNU475 LEFTY2
Mean 0.125
Standard deviation 0.17
Values 0.25 0.0051
[55]
THLE LEFTY2
Mean 0.00592
Standard deviation 0.0084
Values 0.012 0
[56]
liver LEFTY2
Mean 0.0209
Standard deviation 0.034
Values 0.071 0 0 0.013
[57]
ref_hepatocyte NODAL
Mean 0.0065
Standard deviation 0.015
Values 0 0 0 0 0.033
[58]
HepG2 NODAL
Mean 0.214
Standard deviation 0.03
Values 0.23 0.19
[59]
HepG2.C3A NODAL
Mean 0.0146
Standard deviation 0.021
Values 0.029 0
[60]
HuH.7 NODAL
Mean 0.391
Standard deviation 0.15
Values 0.43 0.51 0.22
[61]
SNU475 NODAL
Mean 0.141
Standard deviation 0.029
Values 0.12 0.16
[62]
THLE NODAL
Mean 0.0648
Standard deviation 0.0088
Values 0.071 0.059
[63]
liver NODAL
Mean 0.236
Standard deviation 0.26
Values 0.024 0.29 0.051 0.58
[64]
ref_hepatocyte CER1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[65]
HepG2 CER1
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[66]
HepG2.C3A CER1
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[67]
HuH.7 CER1
Mean 0
Standard deviation 0
Values 0 0 0
[68]
SNU475 CER1
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[69]
THLE CER1
Mean 0
Standard deviation 0
Values 0 0
[70]
liver CER1
Mean 0.00999
Standard deviation 0.012
Values 0 0.014 0.026 0
[71]
ref_hepatocyte TDGF1P3
Missing
[72]
HepG2 TDGF1P3
Mean 0.0479
Standard deviation 0.011
Values 0.04 0.056
[73]
HepG2.C3A TDGF1P3
Mean 0.0511
Standard deviation 0.0036
Values 0.049 0.054
[74]
HuH.7 TDGF1P3
Mean 0.0248
Standard deviation 0.02
Values 0.0082 0.019 0.047
[75]
SNU475 TDGF1P3
Mean 0.0173
Standard deviation 0.011
Values 0.0093 0.025
[76]
THLE TDGF1P3
Mean 0.0281
Standard deviation 0.0021
Values 0.03 0.027
[77]
liver TDGF1P3
Mean 0.054
Standard deviation 0.052
Values 0 0.071 0.026 0.12
[78]
ref_hepatocyte CFC1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[79]
HepG2 CFC1
Missing
[80]
HepG2.C3A CFC1
Missing
[81]
HuH.7 CFC1
Missing
[82]
SNU475 CFC1
Missing
[83]
THLE CFC1
Missing
[84]
liver CFC1
Missing