REACTOME_REGULATION_OF_RUNX3_EXPRESSION_AND_ACTIVITY | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | UBB | Polyubiquitin-B | [1] | -1.12[2] | -1.17[3] | -0.97[4] | -1.36[5] | -1.01[6] | -0.41[7] |
2 | RPS27A | Ubiquitin-40S ribosomal protein S27a | [8] | [9] | [10] | [11] | [12] | [13] | [14] |
3 | UBC | Polyubiquitin-C | [15] | -0.68[16] | -0.42[17] | -0.61[18] | -0.50[19] | -0.63[20] | 0.05[21] |
4 | PSME1 | Proteasome activator complex subunit 1 | [22] | -0.45[23] | -2.01[24] | -1.58[25] | -1.22[26] | -1.86[27] | -0.91[28] |
5 | PSME2 | Proteasome activator complex subunit 2 | [29] | -0.27[30] | -1.63[31] | -1.67[32] | -1.01[33] | -1.39[34] | -0.53[35] |
6 | PSMA7 | Proteasome subunit alpha type-7 | [36] | 0.69[37] | 0.84[38] | -0.42[39] | 0.62[40] | 0.08[41] | 0.49[42] |
7 | PSMB1 | Proteasome subunit beta type-1 | [43] | 0.23[44] | 0.39[45] | -0.62[46] | -0.63[47] | 0.04[48] | 0.33[49] |
8 | PSMB3 | Proteasome subunit beta type-3 | [50] | -0.25[51] | -0.99[52] | 0.11[53] | -0.65[54] | -0.86[55] | 0.03[56] |
9 | PSMB4 | Proteasome subunit beta type-4 | [57] | 0.00[58] | 0.21[59] | 0.41[60] | 0.78[61] | 0.68[62] | -0.29[63] |
10 | PSMB7 | Proteasome subunit beta type-7 | [64] | -0.95[65] | -0.89[66] | -0.69[67] | -0.99[68] | -0.65[69] | -0.73[70] |
11 | PSMB5 | Proteasome subunit beta type-5 | [71] | 1.45[72] | 0.07[73] | 0.06[74] | -0.27[75] | -0.08[76] | -0.26[77] |
12 | PSMA6 | Proteasome subunit alpha type-6 | [78] | 1.58[79] | 0.35[80] | 0.35[81] | 0.26[82] | 0.18[83] | -0.18[84] |
13 | PSMA4 | Proteasome subunit alpha type-4 | [85] | -0.35[86] | 0.36[87] | 0.23[88] | 0.56[89] | 0.29[90] | -0.26[91] |
14 | PSMC3 | 26S proteasome regulatory subunit 6A | [92] | -0.38[93] | -0.40[94] | 0.29[95] | -0.64[96] | -0.53[97] | 0.22[98] |
15 | PSMA3 | Proteasome subunit alpha type-3 | [99] | -0.97[100] | 0.08[101] | -0.53[102] | 0.11[103] | -0.43[104] | -0.01[105] |
16 | PSMB6 | Proteasome subunit beta type-6 | [106] | -0.42[107] | -0.22[108] | -0.01[109] | -0.44[110] | -0.80[111] | 0.15[112] |
17 | PSMA2 | Proteasome subunit alpha type-2 | [113] | -0.51[114] | 0.50[115] | 0.91[116] | 0.06[117] | 0.34[118] | 0.37[119] |
18 | PSMD4 | 26S proteasome non-ATPase regulatory subunit 4 | [120] | 0.01[121] | 0.08[122] | 0.35[123] | 0.76[124] | 0.13[125] | 0.05[126] |
19 | PSMD7 | 26S proteasome non-ATPase regulatory subunit 7 | [127] | -0.07[128] | 0.35[129] | 0.28[130] | -0.33[131] | 0.06[132] | -0.13[133] |
20 | PSMD8 | 26S proteasome non-ATPase regulatory subunit 8 | [134] | 0.10[135] | 0.39[136] | 0.59[137] | -0.05[138] | 0.62[139] | -0.10[140] |
21 | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2 | [141] | 1.63[142] | 0.86[143] | 1.00[144] | 1.06[145] | 2.26[146] | 0.94[147] |
22 | PSMC1 | 26S proteasome regulatory subunit 4 | [148] | -0.05[149] | 0.07[150] | -0.51[151] | 1.24[152] | 0.68[153] | 0.10[154] |
23 | PSMA1 | Proteasome subunit alpha type-1 | [155] | 0.13[156] | 0.58[157] | 0.71[158] | 0.82[159] | 0.23[160] | 0.58[161] |
24 | UBA52 | Ubiquitin-60S ribosomal protein L40 | [162] | 1.76[163] | 1.82[164] | 2.90[165] | 0.89[166] | 1.59[167] | 0.82[168] |
25 | PSMC5 | 26S proteasome regulatory subunit 8 | [169] | 0.45[170] | 0.40[171] | 0.54[172] | 0.23[173] | 0.55[174] | 0.35[175] |
26 | PSMD3 | 26S proteasome non-ATPase regulatory subunit 3 | [176] | 0.85[177] | 0.39[178] | 1.06[179] | 0.76[180] | 0.89[181] | 0.07[182] |
27 | PSMB8 | Proteasome subunit beta type-8 | [183] | -1.55[184] | -2.09[185] | -9.23[186] | 0.73[187] | -0.66[188] | -0.62[189] |
28 | PSMD14 | 26S proteasome non-ATPase regulatory subunit 14 | [190] | 0.02[191] | 0.69[192] | 1.01[193] | 0.62[194] | 0.57[195] | -0.08[196] |
29 | PSMC4 | 26S proteasome regulatory subunit 6B | [197] | 0.45[198] | 0.53[199] | 0.54[200] | 0.25[201] | 0.28[202] | 0.40[203] |
30 | PSMD6 | 26S proteasome non-ATPase regulatory subunit 6 | [204] | -0.70[205] | -0.17[206] | -1.19[207] | -0.37[208] | 0.35[209] | -0.19[210] |
31 | PSMD13 | 26S proteasome non-ATPase regulatory subunit 13 | [211] | 0.50[212] | 0.66[213] | 1.23[214] | 0.68[215] | 0.10[216] | 0.00[217] |
32 | PSMD12 | 26S proteasome non-ATPase regulatory subunit 12 | [218] | -0.33[219] | -0.19[220] | -0.43[221] | 0.30[222] | 0.28[223] | -0.08[224] |
33 | PSMC6 | 26S proteasome regulatory subunit 10B | [225] | -0.03[226] | 1.60[227] | 0.49[228] | 0.66[229] | 0.51[230] | 0.57[231] |
34 | PSMD11 | 26S proteasome non-ATPase regulatory subunit 11 | [232] | 0.85[233] | 0.52[234] | 1.18[235] | 1.07[236] | 1.14[237] | 1.40[238] |
35 | PSMC2 | 26S proteasome regulatory subunit 7 | [239] | 0.61[240] | 1.06[241] | 0.91[242] | 1.46[243] | 1.20[244] | 1.45[245] |
36 | PSME3 | Proteasome activator complex subunit 3 | [246] | 1.84[247] | 1.61[248] | 1.36[249] | 1.49[250] | 1.67[251] | 1.02[252] |
37 | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1 | [253] | 1.60[254] | 1.97[255] | 1.92[256] | 2.29[257] | 2.21[258] | 2.20[259] |
38 | PSMB10 | Proteasome subunit beta type-10 | [260] | -1.13[261] | -0.48[262] | -2.30[263] | 0.08[264] | -1.17[265] | 0.06[266] |
39 | PSMA5 | Proteasome subunit alpha type-5 | [267] | 1.92[268] | 2.40[269] | 2.04[270] | 2.35[271] | 1.82[272] | 2.04[273] |
40 | PSMF1 | Proteasome inhibitor PI31 subunit | [274] | 2.30[275] | 2.40[276] | 1.28[277] | 1.36[278] | 1.03[279] | 1.99[280] |
41 | PSMB2 | Proteasome subunit beta type-2 | [281] | 2.08[282] | 1.87[283] | 2.33[284] | 2.65[285] | 2.55[286] | 2.53[287] |
42 | PSMB9 | Proteasome subunit beta type-9 | [288] | -1.92[289] | -4.49[290] | -6.73[291] | 1.90[292] | -0.46[293] | -0.36[294] |
43 | PSMD9 | 26S proteasome non-ATPase regulatory subunit 9 | [295] | 0.46[296] | 1.00[297] | 0.09[298] | 0.53[299] | 0.88[300] | 0.86[301] |
44 | PSMD10 | 26S proteasome non-ATPase regulatory subunit 10 | [302] | 1.02[303] | 1.39[304] | 1.48[305] | 2.20[306] | 1.43[307] | 0.84[308] |
45 | CBFB | Core-binding factor subunit beta | [309] | 1.62[310] | 2.38[311] | 1.47[312] | 2.26[313] | 2.56[314] | 1.09[315] |
46 | MDM2 | E3 ubiquitin-protein ligase Mdm2 | [316] | 3.18[317] | 4.76[318] | 2.04[319] | 1.93[320] | 2.69[321] | 3.64[322] |
47 | PSMD5 | 26S proteasome non-ATPase regulatory subunit 5 | [323] | 1.44[324] | 1.04[325] | 2.67[326] | 2.58[327] | 2.58[328] | 2.29[329] |
48 | SRC | Proto-oncogene tyrosine-protein kinase Src | [330] | 4.10[331] | 4.24[332] | 3.28[333] | 3.82[334] | 2.88[335] | 0.62[336] |
49 | SMURF1 | E3 ubiquitin-protein ligase SMURF1 | [337] | 2.52[338] | 2.11[339] | 3.07[340] | 2.63[341] | 2.41[342] | 2.85[343] |
50 | EP300 | Histone acetyltransferase p300 | [344] | 3.80[345] | 3.55[346] | 4.49[347] | 3.99[348] | 3.93[349] | 4.23[350] |
51 | TGFB1 | Transforming growth factor beta-1 | [351] | 4.55[352] | 3.66[353] | 0.96[354] | 5.26[355] | 4.38[356] | 0.24[357] |
52 | SMURF2 | E3 ubiquitin-protein ligase SMURF2 | [358] | 2.79[359] | 2.97[360] | 1.53[361] | 2.61[362] | 2.94[363] | 1.61[364] |
53 | CDKN2A | Cyclin-dependent kinase inhibitor 2A | [365] | 5.16[366] | 3.08[367] | 6.53[368] | 6.63[369] | 8.30[370] | -0.68[371] |
54 | RUNX3 | Runt-related transcription factor 3 | [372] | 1.84[373] | 1.01[374] | 4.05[375] | 4.99[376] | -0.32[377] | 2.84[378] |
55 | SEM1 | Putative protein SEM1, isoform 2 | [379] | [380] | [381] | [382] | [383] | [384] | [385] |