REACTOME_REGULATION_OF_RUNX2_EXPRESSION_AND_ACTIVITY | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | UBB | Polyubiquitin-B | [1] | -1.08[2] | -1.16[3] | -1.02[4] | -1.46[5] | -1.03[6] | -0.55[7] |
2 | RPS27A | Ubiquitin-40S ribosomal protein S27a | [8] | [9] | [10] | [11] | [12] | [13] | [14] |
3 | UBC | Polyubiquitin-C | [15] | -0.64[16] | -0.41[17] | -0.66[18] | -0.61[19] | -0.65[20] | -0.09[21] |
4 | PSME1 | Proteasome activator complex subunit 1 | [22] | -0.41[23] | -1.99[24] | -1.63[25] | -1.33[26] | -1.87[27] | -1.05[28] |
5 | PSME2 | Proteasome activator complex subunit 2 | [29] | -0.23[30] | -1.62[31] | -1.72[32] | -1.11[33] | -1.41[34] | -0.67[35] |
6 | PSMA7 | Proteasome subunit alpha type-7 | [36] | 0.73[37] | 0.85[38] | -0.47[39] | 0.51[40] | 0.06[41] | 0.35[42] |
7 | PSMB1 | Proteasome subunit beta type-1 | [43] | 0.27[44] | 0.40[45] | -0.67[46] | -0.73[47] | 0.03[48] | 0.19[49] |
8 | PSMB3 | Proteasome subunit beta type-3 | [50] | -0.21[51] | -0.98[52] | 0.06[53] | -0.75[54] | -0.88[55] | -0.11[56] |
9 | PSMB4 | Proteasome subunit beta type-4 | [57] | 0.04[58] | 0.22[59] | 0.36[60] | 0.68[61] | 0.66[62] | -0.43[63] |
10 | PSMB7 | Proteasome subunit beta type-7 | [64] | -0.91[65] | -0.88[66] | -0.74[67] | -1.10[68] | -0.66[69] | -0.87[70] |
11 | PSMB5 | Proteasome subunit beta type-5 | [71] | 1.49[72] | 0.08[73] | 0.01[74] | -0.38[75] | -0.10[76] | -0.40[77] |
12 | PSMA6 | Proteasome subunit alpha type-6 | [78] | 1.62[79] | 0.36[80] | 0.30[81] | 0.15[82] | 0.16[83] | -0.32[84] |
13 | PSMA4 | Proteasome subunit alpha type-4 | [85] | -0.31[86] | 0.37[87] | 0.18[88] | 0.45[89] | 0.28[90] | -0.40[91] |
14 | SKP1 | S-phase kinase-associated protein 1 | [92] | 0.14[93] | 0.66[94] | -0.23[95] | 0.81[96] | 1.01[97] | 0.64[98] |
15 | PSMC3 | 26S proteasome regulatory subunit 6A | [99] | -0.34[100] | -0.39[101] | 0.24[102] | -0.74[103] | -0.55[104] | 0.07[105] |
16 | PSMA3 | Proteasome subunit alpha type-3 | [106] | -0.93[107] | 0.09[108] | -0.57[109] | 0.00[110] | -0.45[111] | -0.15[112] |
17 | PSMB6 | Proteasome subunit beta type-6 | [113] | -0.38[114] | -0.21[115] | -0.06[116] | -0.55[117] | -0.81[118] | 0.01[119] |
18 | PSMA2 | Proteasome subunit alpha type-2 | [120] | -0.47[121] | 0.52[122] | 0.86[123] | -0.05[124] | 0.32[125] | 0.23[126] |
19 | PSMD4 | 26S proteasome non-ATPase regulatory subunit 4 | [127] | 0.05[128] | 0.09[129] | 0.30[130] | 0.65[131] | 0.12[132] | -0.09[133] |
20 | PSMD7 | 26S proteasome non-ATPase regulatory subunit 7 | [134] | -0.03[135] | 0.37[136] | 0.23[137] | -0.43[138] | 0.04[139] | -0.27[140] |
21 | PSMD8 | 26S proteasome non-ATPase regulatory subunit 8 | [141] | 0.14[142] | 0.40[143] | 0.54[144] | -0.16[145] | 0.60[146] | -0.24[147] |
22 | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2 | [148] | 1.67[149] | 0.87[150] | 0.95[151] | 0.95[152] | 2.25[153] | 0.80[154] |
23 | PSMC1 | 26S proteasome regulatory subunit 4 | [155] | -0.01[156] | 0.08[157] | -0.56[158] | 1.14[159] | 0.66[160] | -0.04[161] |
24 | PSMA1 | Proteasome subunit alpha type-1 | [162] | 0.17[163] | 0.59[164] | 0.66[165] | 0.71[166] | 0.21[167] | 0.44[168] |
25 | UBA52 | Ubiquitin-60S ribosomal protein L40 | [169] | 1.80[170] | 1.83[171] | 2.85[172] | 0.79[173] | 1.58[174] | 0.67[175] |
26 | PSMC5 | 26S proteasome regulatory subunit 8 | [176] | 0.49[177] | 0.41[178] | 0.50[179] | 0.12[180] | 0.53[181] | 0.21[182] |
27 | RBX1 | E3 ubiquitin-protein ligase RBX1 | [183] | -0.94[184] | -0.38[185] | -0.51[186] | -1.39[187] | -0.99[188] | -0.77[189] |
28 | PSMD3 | 26S proteasome non-ATPase regulatory subunit 3 | [190] | 0.89[191] | 0.41[192] | 1.01[193] | 0.65[194] | 0.88[195] | -0.07[196] |
29 | PSMB8 | Proteasome subunit beta type-8 | [197] | -1.51[198] | -2.08[199] | -9.28[200] | 0.62[201] | -0.68[202] | -0.76[203] |
30 | PSMD14 | 26S proteasome non-ATPase regulatory subunit 14 | [204] | 0.07[205] | 0.70[206] | 0.96[207] | 0.51[208] | 0.55[209] | -0.22[210] |
31 | PSMC4 | 26S proteasome regulatory subunit 6B | [211] | 0.49[212] | 0.55[213] | 0.49[214] | 0.14[215] | 0.26[216] | 0.26[217] |
32 | PSMD6 | 26S proteasome non-ATPase regulatory subunit 6 | [218] | -0.66[219] | -0.15[220] | -1.24[221] | -0.48[222] | 0.33[223] | -0.33[224] |
33 | PSMD13 | 26S proteasome non-ATPase regulatory subunit 13 | [225] | 0.54[226] | 0.67[227] | 1.18[228] | 0.58[229] | 0.09[230] | -0.14[231] |
34 | PSMD12 | 26S proteasome non-ATPase regulatory subunit 12 | [232] | -0.29[233] | -0.18[234] | -0.48[235] | 0.20[236] | 0.27[237] | -0.22[238] |
35 | STUB1 | E3 ubiquitin-protein ligase CHIP | [239] | -0.87[240] | -0.72[241] | -1.39[242] | -1.35[243] | -1.04[244] | -0.92[245] |
36 | PSMC6 | 26S proteasome regulatory subunit 10B | [246] | 0.01[247] | 1.61[248] | 0.44[249] | 0.55[250] | 0.49[251] | 0.43[252] |
37 | PSMD11 | 26S proteasome non-ATPase regulatory subunit 11 | [253] | 0.89[254] | 0.53[255] | 1.13[256] | 0.96[257] | 1.12[258] | 1.26[259] |
38 | PSMC2 | 26S proteasome regulatory subunit 7 | [260] | 0.65[261] | 1.08[262] | 0.86[263] | 1.36[264] | 1.19[265] | 1.31[266] |
39 | PSME3 | Proteasome activator complex subunit 3 | [267] | 1.88[268] | 1.62[269] | 1.31[270] | 1.38[271] | 1.65[272] | 0.88[273] |
40 | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1 | [274] | 1.64[275] | 1.98[276] | 1.87[277] | 2.19[278] | 2.20[279] | 2.06[280] |
41 | PSMB10 | Proteasome subunit beta type-10 | [281] | -1.09[282] | -0.47[283] | -2.35[284] | -0.02[285] | -1.19[286] | -0.08[287] |
42 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | [288] | 1.04[289] | 0.25[290] | 1.34[291] | 3.85[292] | 1.56[293] | 2.28[294] |
43 | PSMA5 | Proteasome subunit alpha type-5 | [295] | 1.96[296] | 2.42[297] | 1.99[298] | 2.24[299] | 1.80[300] | 1.90[301] |
44 | PSMF1 | Proteasome inhibitor PI31 subunit | [302] | 2.34[303] | 2.41[304] | 1.23[305] | 1.25[306] | 1.01[307] | 1.85[308] |
45 | PSMB2 | Proteasome subunit beta type-2 | [309] | 2.12[310] | 1.88[311] | 2.28[312] | 2.54[313] | 2.53[314] | 2.39[315] |
46 | PSMB9 | Proteasome subunit beta type-9 | [316] | -1.88[317] | -4.48[318] | -6.78[319] | 1.80[320] | -0.47[321] | -0.50[322] |
47 | PSMD9 | 26S proteasome non-ATPase regulatory subunit 9 | [323] | 0.50[324] | 1.02[325] | 0.04[326] | 0.42[327] | 0.86[328] | 0.72[329] |
48 | CUL1 | Cullin-1 | [330] | 0.73[331] | 1.54[332] | 1.07[333] | 1.90[334] | 1.53[335] | 2.08[336] |
49 | ESRRA | Steroid hormone receptor ERR1 | [337] | 0.90[338] | 1.85[339] | 1.28[340] | 0.49[341] | 0.43[342] | 1.37[343] |
50 | WWP1 | NEDD4-like E3 ubiquitin-protein ligase WWP1 | [344] | 1.12[345] | 2.28[346] | 2.64[347] | 1.10[348] | 0.67[349] | 3.49[350] |
51 | PSMD10 | 26S proteasome non-ATPase regulatory subunit 10 | [351] | 1.06[352] | 1.40[353] | 1.43[354] | 2.09[355] | 1.41[356] | 0.70[357] |
52 | PSME4 | Proteasome activator complex subunit 4 | [358] | 2.58[359] | 3.52[360] | 3.53[361] | 2.65[362] | 2.61[363] | 2.97[364] |
53 | CBFB | Core-binding factor subunit beta | [365] | 1.66[366] | 2.39[367] | 1.42[368] | 2.15[369] | 2.55[370] | 0.95[371] |
54 | NR3C1 | Glucocorticoid receptor | [372] | 1.15[373] | 0.85[374] | 1.14[375] | 2.79[376] | 2.88[377] | 3.10[378] |
55 | PSMD5 | 26S proteasome non-ATPase regulatory subunit 5 | [379] | 1.48[380] | 1.05[381] | 2.62[382] | 2.48[383] | 2.56[384] | 2.15[385] |
56 | BMP2 | Bone morphogenetic protein 2 | [386] | -3.86[387] | -6.87[388] | 2.21[389] | -0.57[390] | -0.35[391] | -0.85[392] |
57 | GSK3B | Glycogen synthase kinase-3 beta | [393] | 2.38[394] | 2.14[395] | 2.70[396] | 3.13[397] | 2.94[398] | 2.49[399] |
58 | SKP2 | S-phase kinase-associated protein 2 | [400] | 2.43[401] | 3.01[402] | 4.14[403] | 2.58[404] | 2.64[405] | 2.41[406] |
59 | SMURF1 | E3 ubiquitin-protein ligase SMURF1 | [407] | 2.56[408] | 2.13[409] | 3.02[410] | 2.53[411] | 2.40[412] | 2.71[413] |
60 | FBXW7 | F-box/WD repeat-containing protein 7 | [414] | 0.38[415] | 1.18[416] | 1.14[417] | 0.42[418] | 1.41[419] | 2.48[420] |
61 | PPARGC1 | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | 0.03[421] | 3.04[422] | -7.75[423] | 2.08[424] | -1.25[425] | 4.77[426] | |
62 | ESR1 | Estrogen receptor | [427] | -6.19[428] | [429] | -4.56[430] | -2.85[431] | -5.14[432] | 3.73[433] |
63 | PPARGC1 | Peroxisome proliferator-activated receptor gamma coactivator 1-beta | 3.48[434] | -0.31[435] | 5.44[436] | 3.98[437] | 4.33[438] | 6.27[439] | |
64 | HIVEP3 | Transcription factor HIVEP3 | [440] | 0.66[441] | -1.81[442] | -0.23[443] | 6.34[444] | 6.71[445] | 5.79[446] |
65 | RUNX2 | Runt-related transcription factor 2 | [447] | 0.27[448] | 0.04[449] | 5.09[450] | 8.44[451] | 10.37[452] | 4.95[453] |
66 | DLX6 | Homeobox protein DLX-6 | [454] | 7.28[455] | 7.17[456] | 7.53[457] | 7.40[458] | [459] | [460] |
67 | MSX2 | Homeobox protein MSX-2 | [461] | [462] | [463] | [464] | [465] | [466] | [467] |
68 | TWIST1 | Twist-related protein 1 | [468] | [469] | [470] | [471] | [472] | [473] | [474] |
69 | NKX3-2 | Homeobox protein Nkx-3.2 | [475] | [476] | [477] | [478] | [479] | [480] | [481] |
70 | DLX5 | Homeobox protein DLX-5 | [482] | [483] | [484] | [485] | [486] | [487] | [488] |
71 | PSMB11 | Proteasome subunit beta type-11 | [489] | [490] | [491] | [492] | [493] | [494] | [495] |
72 | SEM1 | Putative protein SEM1, isoform 2 | [496] | [497] | [498] | [499] | [500] | [501] | [502] |
73 | PSMA8 | Proteasome subunit alpha type-7-like | [503] | [504] | [505] | [506] | [507] | [508] | [509] |