REACTOME_REGULATION_OF_RUNX1_EXPRESSION_AND_ACTIVITY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CCND1 G1/S-specific cyclin-D1 [1] 0.95[2] -0.83[3] 0.01[4] 0.05[5] -1.08[6] -0.52[7]
2 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 [8] -1.65[9] -0.50[10] -0.54[11] -0.94[12] 0.04[13] -0.31[14]
3 CBFB Core-binding factor subunit beta [15] -1.55[16] -0.22[17] -1.18[18] -1.00[19] -0.23[20] -1.95[21]
4 MOV10 Putative helicase MOV-10 [22] -1.11[23] -0.17[24] -0.18[25] -0.76[26] -0.56[27] -0.49[28]
5 CDK6 Cyclin-dependent kinase 6 [29] -0.05[30] 1.37[31] -0.22[32] -0.92[33] 0.23[34] 0.50[35]
6 PML Protein PML [36] -1.86[37] -2.15[38] -0.45[39] 0.05[40] -0.10[41] -1.33[42]
7 SRC Proto-oncogene tyrosine-protein kinase Src [43] 0.93[44] 1.63[45] 0.64[46] 0.57[47] 0.09[48] -2.42[49]
8 CCND3 G1/S-specific cyclin-D3 [50] -1.15[51] -1.49[52] -3.11[53] 1.83[54] 1.35[55] -0.92[56]
9 TNRC6A Trinucleotide repeat-containing gene 6A protein [57] 0.15[58] 1.52[59] 0.71[60] 0.45[61] 0.84[62] 1.42[63]
10 RUNX1 Runt-related transcription factor 1 [64] -0.89[65] -1.38[66] -1.27[67] 0.35[68] 0.40[69] -2.21[70]
11 TNRC6B Trinucleotide repeat-containing gene 6B protein [71] 0.13[72] 1.06[73] 2.74[74] 0.89[75] 1.21[76] 3.77[77]
12 CCND2 G1/S-specific cyclin-D2 [78] 1.04[79] 0.35[80] -5.85[81] -6.28[82] -3.02[83] 0.28[84]
13 TNRC6C Trinucleotide repeat-containing gene 6C protein [85] -0.01[86] 0.66[87] 0.95[88] -1.07[89] -0.74[90] 1.73[91]
14 AGO2 Protein argonaute-2 [92] [93] [94] [95] [96] [97] [98]
15 AGO4 Protein argonaute-4 [99] [100] [101] [102] [103] [104] [105]
16 AGO3 Protein argonaute-3 [106] [107] [108] [109] [110] [111] [112]
17 AGO1 Protein argonaute-1 [113] [114] [115] [116] [117] [118] [119]
[1]
ref_hepatocyte CCND1
Mean 23
Standard deviation 14
Values 44 28 19 11 12
[2]
HepG2 CCND1
Mean 421
Standard deviation 48
Values 4.5e+02 3.9e+02
[3]
HepG2.C3A CCND1
Mean 66.1
Standard deviation 12
Values 58 74
[4]
HuH.7 CCND1
Mean 113
Standard deviation 31
Values 1.4e+02 79 1.2e+02
[5]
SNU475 CCND1
Mean 155
Standard deviation 66
Values 1.1e+02 2e+02
[6]
THLE CCND1
Mean 62.5
Standard deviation 6.4
Values 67 58
[7]
liver CCND1
Mean 67.8
Standard deviation 49
Values 26 1.1e+02 1.1e+02 25
[8]
ref_hepatocyte PTPN11
Mean 22.2
Standard deviation 20
Values 33 53 10 7.5 7.4
[9]
HepG2 PTPN11
Mean 66.7
Standard deviation 12
Values 58 76
[10]
HepG2.C3A PTPN11
Mean 80.2
Standard deviation 17
Values 68 92
[11]
HuH.7 PTPN11
Mean 74.5
Standard deviation 12
Values 86 77 61
[12]
SNU475 PTPN11
Mean 75.4
Standard deviation 0.72
Values 75 76
[13]
THLE PTPN11
Mean 131
Standard deviation 5.1
Values 1.3e+02 1.3e+02
[14]
liver PTPN11
Mean 75.4
Standard deviation 18
Values 60 99 62 80
[15]
ref_hepatocyte CBFB
Mean 7.69
Standard deviation 6.8
Values 17 12 3.4 2.3 3.1
[16]
HepG2 CBFB
Mean 24.8
Standard deviation 2.9
Values 23 27
[17]
HepG2.C3A CBFB
Mean 33.6
Standard deviation 8
Values 28 39
[18]
HuH.7 CBFB
Mean 16.5
Standard deviation 4.3
Values 19 12 19
[19]
SNU475 CBFB
Mean 25.2
Standard deviation 0.84
Values 26 25
[20]
THLE CBFB
Mean 37.8
Standard deviation 4.4
Values 35 41
[21]
liver CBFB
Mean 8.39
Standard deviation 1.4
Values 7.5 9 10 7
[22]
ref_hepatocyte MOV10
Mean 7.44
Standard deviation 2.3
Values 8.8 4.2 6.4 7.7 10
[23]
HepG2 MOV10
Mean 32.5
Standard deviation 7.5
Values 27 38
[24]
HepG2.C3A MOV10
Mean 33.7
Standard deviation 5.4
Values 38 30
[25]
HuH.7 MOV10
Mean 32
Standard deviation 2.1
Values 34 30 32
[26]
SNU475 MOV10
Mean 28.8
Standard deviation 12
Values 37 20
[27]
THLE MOV10
Mean 29
Standard deviation 2.4
Values 27 31
[28]
liver MOV10
Mean 22.3
Standard deviation 6.3
Values 30 16 24 19
[29]
ref_hepatocyte CDK6
Mean 4.05
Standard deviation 4.3
Values 11 4 3.6 0.49 1.1
[30]
HepG2 CDK6
Mean 36.9
Standard deviation 11
Values 29 45
[31]
HepG2.C3A CDK6
Mean 53.4
Standard deviation 2.1
Values 55 52
[32]
HuH.7 CDK6
Mean 16.9
Standard deviation 4
Values 21 16 13
[33]
SNU475 CDK6
Mean 14
Standard deviation 3.1
Values 16 12
[34]
THLE CDK6
Mean 27.4
Standard deviation 3.5
Values 30 25
[35]
liver CDK6
Mean 24.2
Standard deviation 8
Values 24 32 13 28
[36]
ref_hepatocyte PML
Mean 3.77
Standard deviation 3.1
Values 0.6 4.7 8.7 2.5 2.3
[37]
HepG2 PML
Mean 9.79
Standard deviation 1.6
Values 11 8.6
[38]
HepG2.C3A PML
Mean 4.34
Standard deviation 1.3
Values 5.2 3.4
[39]
HuH.7 PML
Mean 13.5
Standard deviation 2.4
Values 16 12 12
[40]
SNU475 PML
Mean 25.6
Standard deviation 4.6
Values 29 22
[41]
THLE PML
Mean 20.2
Standard deviation 3.6
Values 18 23
[42]
liver PML
Mean 6.32
Standard deviation 2.7
Values 10 4.1 6.5 4.7
[43]
ref_hepatocyte SRC
Mean 3.67
Standard deviation 3.6
Values 9.6 4.7 2.2 0.77 1.2
[44]
HepG2 SRC
Mean 66
Standard deviation 21
Values 81 51
[45]
HepG2.C3A SRC
Mean 58.1
Standard deviation 18
Values 71 45
[46]
HuH.7 SRC
Mean 27.9
Standard deviation 2
Values 28 29 26
[47]
SNU475 SRC
Mean 35.6
Standard deviation 3.5
Values 38 33
[48]
THLE SRC
Mean 22.5
Standard deviation 2.7
Values 21 24
[49]
liver SRC
Mean 2.9
Standard deviation 1
Values 4.1 2.5 1.7 3.2
[50]
ref_hepatocyte CCND3
Mean 3.59
Standard deviation 2.1
Values 0.75 3.2 3.5 6.6 3.9
[51]
HepG2 CCND3
Mean 15.4
Standard deviation 1
Values 15 16
[52]
HepG2.C3A CCND3
Mean 6.55
Standard deviation 2.7
Values 4.7 8.4
[53]
HuH.7 CCND3
Mean 2.03
Standard deviation 0.8
Values 2.3 1.1 2.6
[54]
SNU475 CCND3
Mean 83.7
Standard deviation 2.9
Values 82 86
[55]
THLE CCND3
Mean 52.9
Standard deviation 6.7
Values 48 58
[56]
liver CCND3
Mean 8.04
Standard deviation 5
Values 10 3.8 14 4.1
[57]
ref_hepatocyte TNRC6A
Mean 2.71
Standard deviation 1.3
Values 4.9 2.4 2.6 1.4 2.2
[58]
HepG2 TNRC6A
Mean 28.4
Standard deviation 12
Values 20 37
[59]
HepG2.C3A TNRC6A
Mean 39.7
Standard deviation 2.7
Values 38 42
[60]
HuH.7 TNRC6A
Mean 21.6
Standard deviation 3.9
Values 23 24 17
[61]
SNU475 TNRC6A
Mean 24.3
Standard deviation 0.59
Values 25 24
[62]
THLE TNRC6A
Mean 28
Standard deviation 4.4
Values 25 31
[63]
liver TNRC6A
Mean 30.7
Standard deviation 11
Values 25 46 20 33
[64]
ref_hepatocyte RUNX1
Mean 2.34
Standard deviation 3.6
Values 0.45 0.91 8.7 1.1 0.48
[65]
HepG2 RUNX1
Mean 11.9
Standard deviation 4.1
Values 15 9.1
[66]
HepG2.C3A RUNX1
Mean 4.58
Standard deviation 0.1
Values 4.5 4.7
[67]
HuH.7 RUNX1
Mean 4.74
Standard deviation 1.4
Values 5.9 3.1 5.2
[68]
SNU475 RUNX1
Mean 19.5
Standard deviation 1.9
Values 18 21
[69]
THLE RUNX1
Mean 17.8
Standard deviation 0.32
Values 18 18
[70]
liver RUNX1
Mean 2.13
Standard deviation 1
Values 1.6 1.8 1.5 3.7
[71]
ref_hepatocyte TNRC6B
Mean 0.848
Standard deviation 0.29
Values 1 1.3 0.76 0.54 0.67
[72]
HepG2 TNRC6B
Mean 8.77
Standard deviation 2.7
Values 6.8 11
[73]
HepG2.C3A TNRC6B
Mean 9.04
Standard deviation 0.14
Values 8.9 9.1
[74]
HuH.7 TNRC6B
Mean 27.7
Standard deviation 9.5
Values 33 34 17
[75]
SNU475 TNRC6B
Mean 10.3
Standard deviation 1.1
Values 11 9.5
[76]
THLE TNRC6B
Mean 11.3
Standard deviation 2.5
Values 9.5 13
[77]
liver TNRC6B
Mean 48.9
Standard deviation 17
Values 42 59 28 66
[78]
ref_hepatocyte CCND2
Mean 0.667
Standard deviation 0.74
Values 0.071 0.5 0.095 0.79 1.9
[79]
HepG2 CCND2
Mean 13
Standard deviation 3.2
Values 11 15
[80]
HepG2.C3A CCND2
Mean 4.34
Standard deviation 2.4
Values 6.1 2.6
[81]
HuH.7 CCND2
Mean 0.0563
Standard deviation 0.028
Values 0.057 0.083 0.028
[82]
SNU475 CCND2
Mean 0.0561
Standard deviation 0.014
Values 0.046 0.066
[83]
THLE CCND2
Mean 0.473
Standard deviation 0.28
Values 0.67 0.28
[84]
liver CCND2
Mean 3.43
Standard deviation 1
Values 4.4 2.9 2.2 4.2
[85]
ref_hepatocyte TNRC6C
Mean 0.481
Standard deviation 0.3
Values 0.95 0.36 0.21 0.31 0.58
[86]
HepG2 TNRC6C
Mean 4.51
Standard deviation 0.043
Values 4.5 4.5
[87]
HepG2.C3A TNRC6C
Mean 3.88
Standard deviation 0.13
Values 3.8 4
[88]
HuH.7 TNRC6C
Mean 4.53
Standard deviation 0.81
Values 5.3 4.7 3.7
[89]
SNU475 TNRC6C
Mean 1.5
Standard deviation 0.46
Values 1.8 1.2
[90]
THLE TNRC6C
Mean 1.66
Standard deviation 0.014
Values 1.7 1.7
[91]
liver TNRC6C
Mean 6.74
Standard deviation 2.5
Values 4.9 8.6 4.4 9.1
[92]
ref_hepatocyte AGO2
Missing
[93]
HepG2 AGO2
Mean 8.7
Standard deviation 0.3
Values 8.5 8.9
[94]
HepG2.C3A AGO2
Mean 3.98
Standard deviation 0.75
Values 3.5 4.5
[95]
HuH.7 AGO2
Mean 7.66
Standard deviation 4.2
Values 11 9.3 2.9
[96]
SNU475 AGO2
Mean 7.03
Standard deviation 0.082
Values 7 7.1
[97]
THLE AGO2
Mean 8.62
Standard deviation 3.3
Values 6.3 11
[98]
liver AGO2
Mean 6.59
Standard deviation 5
Values 2.8 10 1.8 12
[99]
ref_hepatocyte AGO4
Missing
[100]
HepG2 AGO4
Mean 7.33
Standard deviation 0.39
Values 7.6 7
[101]
HepG2.C3A AGO4
Mean 6.02
Standard deviation 1.9
Values 7.4 4.7
[102]
HuH.7 AGO4
Mean 9.39
Standard deviation 3
Values 8.7 13 6.8
[103]
SNU475 AGO4
Mean 7.87
Standard deviation 2.6
Values 9.7 6
[104]
THLE AGO4
Mean 6.07
Standard deviation 0.55
Values 6.5 5.7
[105]
liver AGO4
Mean 12.1
Standard deviation 8.6
Values 4.5 22 5.4 16
[106]
ref_hepatocyte AGO3
Missing
[107]
HepG2 AGO3
Mean 3.11
Standard deviation 1.2
Values 2.3 3.9
[108]
HepG2.C3A AGO3
Mean 2.68
Standard deviation 0.41
Values 2.4 3
[109]
HuH.7 AGO3
Mean 2.94
Standard deviation 0.85
Values 3 3.8 2.1
[110]
SNU475 AGO3
Mean 4.2
Standard deviation 0.38
Values 4.5 3.9
[111]
THLE AGO3
Mean 3.9
Standard deviation 0.43
Values 3.6 4.2
[112]
liver AGO3
Mean 9.72
Standard deviation 3.7
Values 7.4 13 5.8 12
[113]
ref_hepatocyte AGO1
Missing
[114]
HepG2 AGO1
Mean 20.3
Standard deviation 2.8
Values 18 22
[115]
HepG2.C3A AGO1
Mean 11.1
Standard deviation 1.1
Values 10 12
[116]
HuH.7 AGO1
Mean 27.7
Standard deviation 9.7
Values 39 23 21
[117]
SNU475 AGO1
Mean 21.2
Standard deviation 5.4
Values 25 17
[118]
THLE AGO1
Mean 13.5
Standard deviation 1.7
Values 12 15
[119]
liver AGO1
Mean 12.3
Standard deviation 5.7
Values 8.4 15 6.8 19