REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELE | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | UBB | Polyubiquitin-B | [1] | -1.26[2] | -1.34[3] | -1.26[4] | -1.82[5] | -1.23[6] | -0.50[7] |
2 | RPS27A | Ubiquitin-40S ribosomal protein S27a | [8] | [9] | [10] | [11] | [12] | [13] | [14] |
3 | UBC | Polyubiquitin-C | [15] | -0.81[16] | -0.58[17] | -0.89[18] | -0.97[19] | -0.85[20] | -0.05[21] |
4 | HSPA8 | Heat shock cognate 71 kDa protein | [22] | 0.62[23] | 0.74[24] | -0.02[25] | 0.92[26] | 0.76[27] | 0.30[28] |
5 | HSPB1 | Heat shock protein beta-1 | [29] | -2.55[30] | -3.25[31] | -2.56[32] | -0.44[33] | -2.47[34] | -2.43[35] |
6 | HSPA1A | Heat shock 70 kDa protein 1A | [36] | -4.64[37] | -4.19[38] | -5.36[39] | -3.97[40] | -5.28[41] | -4.37[42] |
7 | PABPC1 | Polyadenylate-binding protein 1 | [43] | 0.29[44] | 0.80[45] | 1.49[46] | 0.08[47] | 0.19[48] | -0.24[49] |
8 | PSME1 | Proteasome activator complex subunit 1 | [50] | -0.58[51] | -2.17[52] | -1.86[53] | -1.69[54] | -2.07[55] | -1.00[56] |
9 | YWHAZ | 14-3-3 protein zeta/delta | [57] | 0.37[58] | 0.34[59] | 0.59[60] | 1.86[61] | 0.58[62] | -0.27[63] |
10 | PSME2 | Proteasome activator complex subunit 2 | [64] | -0.40[65] | -1.80[66] | -1.95[67] | -1.47[68] | -1.61[69] | -0.62[70] |
11 | PSMA7 | Proteasome subunit alpha type-7 | [71] | 0.56[72] | 0.67[73] | -0.70[74] | 0.15[75] | -0.13[76] | 0.40[77] |
12 | PSMB1 | Proteasome subunit beta type-1 | [78] | 0.10[79] | 0.22[80] | -0.90[81] | -1.09[82] | -0.17[83] | 0.24[84] |
13 | PSMB3 | Proteasome subunit beta type-3 | [85] | -0.38[86] | -1.16[87] | -0.18[88] | -1.11[89] | -1.07[90] | -0.06[91] |
14 | PSMB4 | Proteasome subunit beta type-4 | [92] | -0.14[93] | 0.04[94] | 0.12[95] | 0.31[96] | 0.47[97] | -0.39[98] |
15 | PSMB7 | Proteasome subunit beta type-7 | [99] | -1.08[100] | -1.06[101] | -0.97[102] | -1.46[103] | -0.86[104] | -0.83[105] |
16 | PSMB5 | Proteasome subunit beta type-5 | [106] | 1.32[107] | -0.10[108] | -0.22[109] | -0.74[110] | -0.30[111] | -0.35[112] |
17 | SET | Protein SET | [113] | 0.78[114] | 0.76[115] | 1.35[116] | 0.86[117] | 0.83[118] | 0.26[119] |
18 | PSMA6 | Proteasome subunit alpha type-6 | [120] | 1.45[121] | 0.18[122] | 0.06[123] | -0.21[124] | -0.03[125] | -0.27[126] |
19 | PSMA4 | Proteasome subunit alpha type-4 | [127] | -0.48[128] | 0.19[129] | -0.06[130] | 0.09[131] | 0.08[132] | -0.35[133] |
20 | PSMC3 | 26S proteasome regulatory subunit 6A | [134] | -0.52[135] | -0.57[136] | 0.00[137] | -1.10[138] | -0.74[139] | 0.12[140] |
21 | PSMA3 | Proteasome subunit alpha type-3 | [141] | -1.10[142] | -0.08[143] | -0.81[144] | -0.36[145] | -0.64[146] | -0.10[147] |
22 | PSMB6 | Proteasome subunit beta type-6 | [148] | -0.55[149] | -0.39[150] | -0.29[151] | -0.91[152] | -1.01[153] | 0.06[154] |
23 | PSMA2 | Proteasome subunit alpha type-2 | [155] | -0.64[156] | 0.34[157] | 0.62[158] | -0.41[159] | 0.13[160] | 0.28[161] |
24 | PSMD4 | 26S proteasome non-ATPase regulatory subunit 4 | [162] | -0.12[163] | -0.09[164] | 0.06[165] | 0.29[166] | -0.08[167] | -0.04[168] |
25 | PSMD7 | 26S proteasome non-ATPase regulatory subunit 7 | [169] | -0.20[170] | 0.19[171] | 0.00[172] | -0.79[173] | -0.16[174] | -0.22[175] |
26 | PSMD8 | 26S proteasome non-ATPase regulatory subunit 8 | [176] | -0.04[177] | 0.22[178] | 0.31[179] | -0.52[180] | 0.41[181] | -0.19[182] |
27 | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2 | [183] | 1.49[184] | 0.69[185] | 0.72[186] | 0.59[187] | 2.05[188] | 0.84[189] |
28 | EIF4G1 | Eukaryotic translation initiation factor 4 gamma 1 | [190] | 1.82[191] | 1.14[192] | 1.48[193] | 1.34[194] | 1.87[195] | 2.43[196] |
29 | PSMC1 | 26S proteasome regulatory subunit 4 | [197] | -0.18[198] | -0.10[199] | -0.80[200] | 0.78[201] | 0.47[202] | 0.00[203] |
30 | PSMA1 | Proteasome subunit alpha type-1 | [204] | 0.00[205] | 0.41[206] | 0.42[207] | 0.35[208] | 0.02[209] | 0.49[210] |
31 | UBA52 | Ubiquitin-60S ribosomal protein L40 | [211] | 1.62[212] | 1.65[213] | 2.62[214] | 0.43[215] | 1.38[216] | 0.72[217] |
32 | HNRNPD | Heterogeneous nuclear ribonucleoprotein D0 | [218] | 0.59[219] | 0.27[220] | 0.49[221] | 0.06[222] | 0.46[223] | -1.31[224] |
33 | PSMC5 | 26S proteasome regulatory subunit 8 | [225] | 0.32[226] | 0.23[227] | 0.26[228] | -0.24[229] | 0.34[230] | 0.26[231] |
34 | PSMD3 | 26S proteasome non-ATPase regulatory subunit 3 | [232] | 0.72[233] | 0.23[234] | 0.77[235] | 0.29[236] | 0.68[237] | -0.03[238] |
35 | PSMB8 | Proteasome subunit beta type-8 | [239] | -1.68[240] | -2.25[241] | -9.52[242] | 0.26[243] | -0.88[244] | -0.71[245] |
36 | PSMD14 | 26S proteasome non-ATPase regulatory subunit 14 | [246] | -0.11[247] | 0.52[248] | 0.72[249] | 0.15[250] | 0.35[251] | -0.17[252] |
37 | PSMC4 | 26S proteasome regulatory subunit 6B | [253] | 0.32[254] | 0.37[255] | 0.25[256] | -0.22[257] | 0.06[258] | 0.31[259] |
38 | PSMD6 | 26S proteasome non-ATPase regulatory subunit 6 | [260] | -0.83[261] | -0.33[262] | -1.47[263] | -0.84[264] | 0.13[265] | -0.28[266] |
39 | YWHAB | 14-3-3 protein beta/alpha | [267] | 1.98[268] | 1.81[269] | 1.02[270] | 2.26[271] | 1.83[272] | 1.28[273] |
40 | PSMD13 | 26S proteasome non-ATPase regulatory subunit 13 | [274] | 0.36[275] | 0.49[276] | 0.94[277] | 0.22[278] | -0.11[279] | -0.10[280] |
41 | ZFP36L1 | mRNA decay activator protein ZFP36L1 | [281] | -0.13[282] | -1.05[283] | -0.79[284] | 0.78[285] | 0.47[286] | 1.63[287] |
42 | PSMD12 | 26S proteasome non-ATPase regulatory subunit 12 | [288] | -0.46[289] | -0.36[290] | -0.72[291] | -0.16[292] | 0.07[293] | -0.17[294] |
43 | AKT1 | RAC-alpha serine/threonine-protein kinase | [295] | 1.02[296] | 0.91[297] | -0.24[298] | 0.90[299] | 1.07[300] | 1.13[301] |
44 | PSMC6 | 26S proteasome regulatory subunit 10B | [302] | -0.16[303] | 1.43[304] | 0.20[305] | 0.19[306] | 0.29[307] | 0.48[308] |
45 | PSMD11 | 26S proteasome non-ATPase regulatory subunit 11 | [309] | 0.72[310] | 0.35[311] | 0.90[312] | 0.60[313] | 0.92[314] | 1.30[315] |
46 | ANP32A | Acidic leucine-rich nuclear phosphoprotein 32 family member A | [316] | 0.93[317] | 0.88[318] | 1.52[319] | 0.64[320] | 0.45[321] | -0.19[322] |
47 | PSMC2 | 26S proteasome regulatory subunit 7 | [323] | 0.48[324] | 0.90[325] | 0.62[326] | 1.00[327] | 0.99[328] | 1.36[329] |
48 | PSME3 | Proteasome activator complex subunit 3 | [330] | 1.70[331] | 1.44[332] | 1.07[333] | 1.02[334] | 1.46[335] | 0.92[336] |
49 | ZFP36 | mRNA decay activator protein ZFP36 | [337] | -1.48[338] | -0.92[339] | -2.12[340] | -1.06[341] | -1.54[342] | 1.06[343] |
50 | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1 | [344] | 1.46[345] | 1.80[346] | 1.63[347] | 1.83[348] | 2.00[349] | 2.11[350] |
51 | PSMB10 | Proteasome subunit beta type-10 | [351] | -1.26[352] | -0.65[353] | -2.58[354] | -0.38[355] | -1.38[356] | -0.04[357] |
52 | PSMA5 | Proteasome subunit alpha type-5 | [358] | 1.79[359] | 2.24[360] | 1.75[361] | 1.88[362] | 1.61[363] | 1.95[364] |
53 | EXOSC4 | Exosome complex component RRP41 | [365] | -0.58[366] | -0.09[367] | -0.80[368] | -0.88[369] | -1.42[370] | -0.29[371] |
54 | PSMF1 | Proteasome inhibitor PI31 subunit | [372] | 2.17[373] | 2.23[374] | 0.99[375] | 0.89[376] | 0.81[377] | 1.89[378] |
55 | EXOSC7 | Exosome complex component RRP42 | [379] | -0.41[380] | -0.31[381] | 0.19[382] | -1.76[383] | -0.66[384] | -0.47[385] |
56 | PSMB2 | Proteasome subunit beta type-2 | [386] | 1.95[387] | 1.70[388] | 2.04[389] | 2.18[390] | 2.33[391] | 2.44[392] |
57 | KHSRP | Far upstream element-binding protein 2 | [393] | 2.36[394] | 1.71[395] | 3.04[396] | 1.66[397] | 1.98[398] | -0.04[399] |
58 | EXOSC3 | Exosome complex component RRP40 | [400] | -0.16[401] | -0.15[402] | 0.50[403] | -0.98[404] | -0.17[405] | -0.44[406] |
59 | PSMB9 | Proteasome subunit beta type-9 | [407] | -2.05[408] | -4.66[409] | -7.01[410] | 1.44[411] | -0.67[412] | -0.46[413] |
60 | PSMD9 | 26S proteasome non-ATPase regulatory subunit 9 | [414] | 0.33[415] | 0.84[416] | -0.20[417] | 0.06[418] | 0.66[419] | 0.77[420] |
61 | XPO1 | Exportin-1 | [421] | 2.30[422] | 3.13[423] | 3.09[424] | 3.09[425] | 3.32[426] | 2.24[427] |
62 | MAPKAPK | MAP kinase-activated protein kinase 2 | [428] | 1.40[429] | 0.56[430] | 0.90[431] | 2.35[432] | 1.70[433] | 0.44[434] |
63 | EXOSC9 | Exosome complex component RRP45 | [435] | -0.39[436] | 0.17[437] | -0.43[438] | -0.48[439] | 1.34[440] | -0.76[441] |
64 | EXOSC5 | Exosome complex component RRP46 | [442] | 0.00[443] | 0.15[444] | 1.15[445] | -0.96[446] | -0.38[447] | 0.31[448] |
65 | PSMD10 | 26S proteasome non-ATPase regulatory subunit 10 | [449] | 0.88[450] | 1.22[451] | 1.20[452] | 1.73[453] | 1.22[454] | 0.75[455] |
66 | MAPK14 | Mitogen-activated protein kinase 14 | [456] | 2.42[457] | 2.61[458] | 2.11[459] | 2.64[460] | 2.25[461] | 2.66[462] |
67 | PARN | Poly(A)-specific ribonuclease PARN | [463] | 1.87[464] | 1.34[465] | 0.92[466] | 0.91[467] | 1.01[468] | 1.32[469] |
68 | TNPO1 | Transportin-1 | [470] | 2.67[471] | 3.45[472] | 3.25[473] | 4.45[474] | 4.00[475] | 3.45[476] |
69 | PSME4 | Proteasome activator complex subunit 4 | [477] | 2.41[478] | 3.34[479] | 3.29[480] | 2.29[481] | 2.42[482] | 3.02[483] |
70 | EXOSC2 | Exosome complex component RRP4 | [484] | 1.17[485] | 1.12[486] | 1.37[487] | 0.63[488] | 1.71[489] | 0.69[490] |
71 | EXOSC1 | Exosome complex component CSL4 | [491] | 0.85[492] | 1.65[493] | 1.88[494] | 0.05[495] | 1.11[496] | 0.42[497] |
72 | EXOSC6 | Exosome complex component MTR3 | [498] | 0.73[499] | 0.87[500] | -0.43[501] | -0.09[502] | 0.63[503] | 0.74[504] |
73 | PSMD5 | 26S proteasome non-ATPase regulatory subunit 5 | [505] | 1.30[506] | 0.87[507] | 2.39[508] | 2.12[509] | 2.36[510] | 2.20[511] |
74 | EXOSC8 | Exosome complex component RRP43 | [512] | 1.09[513] | 2.04[514] | 2.16[515] | 0.22[516] | 1.41[517] | 0.71[518] |
75 | ELAVL1 | ELAV-like protein 1 | [519] | 3.11[520] | 2.85[521] | 3.20[522] | 2.77[523] | 3.19[524] | 2.46[525] |
76 | PRKCD | Protein kinase C delta type | [526] | 2.04[527] | 2.41[528] | 1.82[529] | 0.45[530] | 1.75[531] | 0.31[532] |
77 | DIS3 | Exosome complex exonuclease RRP44 | [533] | 1.85[534] | 2.99[535] | 3.59[536] | 2.75[537] | 2.94[538] | 3.33[539] |
78 | NUP214 | Nuclear pore complex protein Nup214 | [540] | 2.97[541] | 2.40[542] | 3.45[543] | 3.14[544] | 3.21[545] | 3.13[546] |
79 | TNFSF13 | Tumor necrosis factor ligand superfamily member 13 | [547] | -0.98[548] | -0.76[549] | -3.84[550] | -2.29[551] | -0.58[552] | -0.78[553] |
80 | PRKCA | Protein kinase C alpha type | [554] | 3.78[555] | 3.94[556] | 4.23[557] | 3.11[558] | 3.61[559] | 3.30[560] |
81 | DCP1A | mRNA-decapping enzyme 1A | [561] | 2.76[562] | 3.26[563] | 2.62[564] | 2.34[565] | 3.36[566] | 4.14[567] |
82 | DCP2 | m7GpppN-mRNA hydrolase | [568] | 2.73[569] | 4.57[570] | 3.66[571] | 3.39[572] | 3.42[573] | 4.58[574] |
83 | XRN1 | 5'-3' exoribonuclease 1 | [575] | 1.79[576] | 3.42[577] | 3.73[578] | 3.90[579] | 3.91[580] | 5.87[581] |
84 | MAPK11 | Mitogen-activated protein kinase 11 | [582] | 0.77[583] | 0.79[584] | -0.17[585] | 1.31[586] | 3.44[587] | 1.54[588] |
85 | PSMB11 | Proteasome subunit beta type-11 | [589] | [590] | [591] | [592] | [593] | [594] | [595] |
86 | PSMA8 | Proteasome subunit alpha type-7-like | [596] | [597] | [598] | [599] | [600] | [601] | [602] |
87 | SEM1 | Putative protein SEM1, isoform 2 | [603] | [604] | [605] | [606] | [607] | [608] | [609] |