REACTOME_REGULATION_OF_LOCALIZATION_OF_FOXO_TRANSCRIPTION_FACTORS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 YWHAZ 14-3-3 protein zeta/delta [1] -0.51[2] -0.45[3] -0.02[4] 0.13[5] -0.50[6] -0.82[7]
2 YWHAQ 14-3-3 protein theta [8] 0.32[9] 0.35[10] 0.17[11] 0.58[12] 0.69[13] 0.23[14]
3 SFN 14-3-3 protein sigma [15] -2.30[16] -2.44[17] -1.94[18] -8.61[19] -8.75[20] -9.27[21]
4 YWHAG 14-3-3 protein gamma [22] 0.26[23] -0.06[24] 0.11[25] -0.06[26] 0.04[27] -0.52[28]
5 YWHAB 14-3-3 protein beta/alpha [29] 1.10[30] 1.03[31] 0.41[32] 0.52[33] 0.75[34] 0.73[35]
6 AKT1 RAC-alpha serine/threonine-protein kinase [36] 0.14[37] 0.13[38] -0.85[39] -0.83[40] -0.02[41] 0.58[42]
7 AKT2 RAC-beta serine/threonine-protein kinase [43] 1.02[44] 1.51[45] 1.75[46] 0.08[47] 0.66[48] 1.96[49]
8 FOXO3 Forkhead box protein O3 [50] 0.51[51] 0.82[52] 1.57[53] -0.38[54] 1.65[55] 3.16[56]
9 FOXO1 Forkhead box protein O1 [57] 1.75[58] 1.64[59] 1.88[60] 0.40[61] 3.20[62] 3.92[63]
10 FOXO4 Forkhead box protein O4 [64] 0.79[65] 1.40[66] 1.34[67] -0.61[68] 0.39[69] 0.14[70]
11 AKT3 RAC-gamma serine/threonine-protein kinase [71] -1.78[72] -4.12[73] -3.33[74] 5.07[75] 4.81[76] 4.44[77]
12 FOXO6 Forkhead box protein O6 [78] [79] [80] [81] [82] [83] [84]
[1]
ref_hepatocyte YWHAZ
Mean 161
Standard deviation 1.6e+02
Values 1.3e+02 4.3e+02 1.6e+02 40 41
[2]
HepG2 YWHAZ
Mean 239
Standard deviation 21
Values 2.2e+02 2.5e+02
[3]
HepG2.C3A YWHAZ
Mean 191
Standard deviation 28
Values 1.7e+02 2.1e+02
[4]
HuH.7 YWHAZ
Mean 229
Standard deviation 23
Values 2.5e+02 2.1e+02 2.3e+02
[5]
SNU475 YWHAZ
Mean 552
Standard deviation 94
Values 6.2e+02 4.9e+02
[6]
THLE YWHAZ
Mean 232
Standard deviation 39
Values 2e+02 2.6e+02
[7]
liver YWHAZ
Mean 73.1
Standard deviation 31
Values 81 60 1.1e+02 39
[8]
ref_hepatocyte YWHAQ
Mean 63.6
Standard deviation 28
Values 49 1e+02 86 44 39
[9]
HepG2 YWHAQ
Mean 169
Standard deviation 33
Values 1.5e+02 1.9e+02
[10]
HepG2.C3A YWHAQ
Mean 132
Standard deviation 50
Values 96 1.7e+02
[11]
HuH.7 YWHAQ
Mean 103
Standard deviation 30
Values 1.2e+02 69 1.2e+02
[12]
SNU475 YWHAQ
Mean 299
Standard deviation 36
Values 3.2e+02 2.7e+02
[13]
THLE YWHAQ
Mean 210
Standard deviation 34
Values 1.9e+02 2.3e+02
[14]
liver YWHAQ
Mean 59.7
Standard deviation 29
Values 70 42 95 31
[15]
ref_hepatocyte SFN
Mean 59.2
Standard deviation 90
Values 6.3 2.1e+02 78 1.8 0.87
[16]
HepG2 SFN
Mean 25.4
Standard deviation 7.7
Values 31 20
[17]
HepG2.C3A SFN
Mean 17.7
Standard deviation 2.5
Values 16 19
[18]
HuH.7 SFN
Mean 22.3
Standard deviation 9.2
Values 25 12 30
[19]
SNU475 SFN
Mean 0.477
Standard deviation 0.46
Values 0.15 0.81
[20]
THLE SFN
Mean 0.281
Standard deviation 0.029
Values 0.3 0.26
[21]
liver SFN
Mean 0.0769
Standard deviation 0.053
Values 0 0.086 0.1 0.12
[22]
ref_hepatocyte YWHAG
Mean 50.4
Standard deviation 40
Values 70 1.1e+02 35 18 18
[23]
HepG2 YWHAG
Mean 128
Standard deviation 6.2
Values 1.3e+02 1.2e+02
[24]
HepG2.C3A YWHAG
Mean 78.7
Standard deviation 6.4
Values 74 83
[25]
HuH.7 YWHAG
Mean 78.6
Standard deviation 11
Values 91 70 74
[26]
SNU475 YWHAG
Mean 152
Standard deviation 34
Values 1.8e+02 1.3e+02
[27]
THLE YWHAG
Mean 106
Standard deviation 7.5
Values 1e+02 1.1e+02
[28]
liver YWHAG
Mean 28.2
Standard deviation 12
Values 21 40 15 37
[29]
ref_hepatocyte YWHAB
Mean 42.6
Standard deviation 20
Values 74 47 41 28 22
[30]
HepG2 YWHAB
Mean 193
Standard deviation 37
Values 1.7e+02 2.2e+02
[31]
HepG2.C3A YWHAB
Mean 141
Standard deviation 27
Values 1.2e+02 1.6e+02
[32]
HuH.7 YWHAB
Mean 82.2
Standard deviation 26
Values 98 52 97
[33]
SNU475 YWHAB
Mean 193
Standard deviation 7
Values 2e+02 1.9e+02
[34]
THLE YWHAB
Mean 146
Standard deviation 23
Values 1.3e+02 1.6e+02
[35]
liver YWHAB
Mean 56.6
Standard deviation 26
Values 78 39 80 30
[36]
ref_hepatocyte AKT1
Mean 37.6
Standard deviation 15
Values 55 50 19 31 32
[37]
HepG2 AKT1
Mean 87.8
Standard deviation 2.3
Values 89 86
[38]
HepG2.C3A AKT1
Mean 66.6
Standard deviation 2.4
Values 65 68
[39]
HuH.7 AKT1
Mean 30.2
Standard deviation 6.6
Values 33 23 35
[40]
SNU475 AKT1
Mean 66.6
Standard deviation 14
Values 76 57
[41]
THLE AKT1
Mean 75.8
Standard deviation 6.1
Values 72 80
[42]
liver AKT1
Mean 45.1
Standard deviation 25
Values 34 48 20 79
[43]
ref_hepatocyte AKT2
Mean 10.6
Standard deviation 2.8
Values 7.2 8.4 11 13 14
[44]
HepG2 AKT2
Mean 45.6
Standard deviation 3.3
Values 48 43
[45]
HepG2.C3A AKT2
Mean 49.1
Standard deviation 8.9
Values 55 43
[46]
HuH.7 AKT2
Mean 51.5
Standard deviation 9.8
Values 59 41 55
[47]
SNU475 AKT2
Mean 35.3
Standard deviation 5.9
Values 39 31
[48]
THLE AKT2
Mean 34.2
Standard deviation 3.5
Values 32 37
[49]
liver AKT2
Mean 33
Standard deviation 9.4
Values 24 36 27 45
[50]
ref_hepatocyte FOXO3
Mean 2.79
Standard deviation 0.38
Values 3.3 2.7 2.3 2.8 2.9
[51]
HepG2 FOXO3
Mean 8.44
Standard deviation 1
Values 7.7 9.2
[52]
HepG2.C3A FOXO3
Mean 8
Standard deviation 2.4
Values 9.7 6.3
[53]
HuH.7 FOXO3
Mean 11.9
Standard deviation 3.6
Values 13 15 7.9
[54]
SNU475 FOXO3
Mean 6.76
Standard deviation 0.76
Values 7.3 6.2
[55]
THLE FOXO3
Mean 17.9
Standard deviation 3.1
Values 16 20
[56]
liver FOXO3
Mean 20
Standard deviation 5.5
Values 24 21 12 23
[57]
ref_hepatocyte FOXO1
Mean 1.77
Standard deviation 0.68
Values 0.71 1.7 2 1.9 2.6
[58]
HepG2 FOXO1
Mean 12.6
Standard deviation 1.8
Values 11 14
[59]
HepG2.C3A FOXO1
Mean 8.92
Standard deviation 1.5
Values 10 7.9
[60]
HuH.7 FOXO1
Mean 9.41
Standard deviation 1.6
Values 10 10 7.6
[61]
SNU475 FOXO1
Mean 7.33
Standard deviation 1.8
Values 8.6 6
[62]
THLE FOXO1
Mean 33.2
Standard deviation 1.9
Values 32 35
[63]
liver FOXO1
Mean 21.4
Standard deviation 7
Values 25 19 13 29
[64]
ref_hepatocyte FOXO4
Mean 1.56
Standard deviation 0.85
Values 2.8 1.6 0.42 1.7 1.3
[65]
HepG2 FOXO4
Mean 5.71
Standard deviation 1.3
Values 6.6 4.8
[66]
HepG2.C3A FOXO4
Mean 6.69
Standard deviation 3.6
Values 9.2 4.2
[67]
HuH.7 FOXO4
Mean 5.72
Standard deviation 1.5
Values 5.1 7.5 4.6
[68]
SNU475 FOXO4
Mean 3.21
Standard deviation 1.1
Values 4 2.4
[69]
THLE FOXO4
Mean 4.17
Standard deviation 0.02
Values 4.2 4.2
[70]
liver FOXO4
Mean 1.37
Standard deviation 1.1
Values 0.54 2 0.33 2.6
[71]
ref_hepatocyte AKT3
Mean 0.387
Standard deviation 0.32
Values 0 0.53 0.83 0.16 0.41
[72]
HepG2 AKT3
Mean 0.238
Standard deviation 0.15
Values 0.34 0.13
[73]
HepG2.C3A AKT3
Mean 0.036
Standard deviation 0.0097
Values 0.029 0.043
[74]
HuH.7 AKT3
Mean 0.0557
Standard deviation 0.031
Values 0.049 0.09 0.028
[75]
SNU475 AKT3
Mean 40.8
Standard deviation 10
Values 48 34
[76]
THLE AKT3
Mean 22.1
Standard deviation 4.4
Values 25 19
[77]
liver AKT3
Mean 6.71
Standard deviation 4.9
Values 2.8 12 2.3 9.4
[78]
ref_hepatocyte FOXO6
Missing
[79]
HepG2 FOXO6
Missing
[80]
HepG2.C3A FOXO6
Missing
[81]
HuH.7 FOXO6
Missing
[82]
SNU475 FOXO6
Missing
[83]
THLE FOXO6
Missing
[84]
liver FOXO6
Missing