REACTOME_REGULATION_OF_IFNG_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 SUMO1 Small ubiquitin-related modifier 1 [1] -1.42[2] -1.14[3] -1.34[4] -1.87[5] -1.54[6] -1.68[7]
2 IFNGR1 Interferon gamma receptor 1 [8] 0.95[9] -0.04[10] -1.33[11] -0.78[12] -0.64[13] -0.45[14]
3 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 [15] 0.62[16] 1.18[17] 1.30[18] 0.48[19] 1.50[20] 1.12[21]
4 STAT1 Signal transducer and activator of transcription 1-alpha/beta [22] 0.10[23] -0.69[24] 0.58[25] 2.13[26] 0.24[27] 0.81[28]
5 IFNGR2 Interferon gamma receptor 2 [29] 0.14[30] 0.83[31] -1.03[32] -1.77[33] -0.10[34] -0.72[35]
6 JAK1 Tyrosine-protein kinase JAK1 [36] 0.69[37] 0.30[38] 0.65[39] 0.22[40] 1.25[41] 1.39[42]
7 SOCS3 Suppressor of cytokine signaling 3 [43] -3.97[44] -4.25[45] -2.36[46] -1.20[47] -1.89[48] 0.00[49]
8 PTPN1 Tyrosine-protein phosphatase non-receptor type 1 [50] 1.29[51] 1.08[52] 0.77[53] 1.42[54] 1.10[55] -0.44[56]
9 PTPN2 Tyrosine-protein phosphatase non-receptor type 2 [57] -0.68[58] 0.76[59] 1.31[60] -0.96[61] -0.44[62] -0.39[63]
10 PTPN6 Tyrosine-protein phosphatase non-receptor type 6 [64] -0.29[65] 0.03[66] 0.77[67] -7.54[68] -2.14[69] -0.32[70]
11 PIAS1 E3 SUMO-protein ligase PIAS1 [71] 0.22[72] 0.60[73] 1.67[74] 0.47[75] 0.58[76] 1.05[77]
12 SOCS1 Suppressor of cytokine signaling 1 [78] -1.28[79] -0.28[80] 0.16[81] -2.20[82] -3.20[83] -1.60[84]
13 JAK2 Tyrosine-protein kinase JAK2 [85] 0.40[86] 0.52[87] 0.25[88] 0.36[89] 1.34[90] 2.57[91]
14 IFNG Interferon gamma [92] [93] [94] [95] -1.10[96] [97] -2.43[98]
[1]
ref_hepatocyte SUMO1
Mean 76.3
Standard deviation 10
Values 80 74 89 61 77
[2]
HepG2 SUMO1
Mean 55.7
Standard deviation 4.2
Values 53 59
[3]
HepG2.C3A SUMO1
Mean 55.2
Standard deviation 14
Values 45 65
[4]
HuH.7 SUMO1
Mean 41.2
Standard deviation 13
Values 44 27 53
[5]
SNU475 SUMO1
Mean 50.5
Standard deviation 16
Values 62 40
[6]
THLE SUMO1
Mean 54.6
Standard deviation 7.9
Values 49 60
[7]
liver SUMO1
Mean 37.2
Standard deviation 30
Values 71 13 54 10
[8]
ref_hepatocyte IFNGR1
Mean 28.2
Standard deviation 11
Values 37 29 19 40 17
[9]
HepG2 IFNGR1
Mean 107
Standard deviation 26
Values 89 1.3e+02
[10]
HepG2.C3A IFNGR1
Mean 43.9
Standard deviation 3.3
Values 41 46
[11]
HuH.7 IFNGR1
Mean 15.3
Standard deviation 3.2
Values 12 18 17
[12]
SNU475 IFNGR1
Mean 39.8
Standard deviation 2.9
Values 38 42
[13]
THLE IFNGR1
Mean 37.6
Standard deviation 3.6
Values 40 35
[14]
liver IFNGR1
Mean 32.2
Standard deviation 10
Values 35 27 46 22
[15]
ref_hepatocyte PTPN11
Mean 22.2
Standard deviation 20
Values 33 53 10 7.5 7.4
[16]
HepG2 PTPN11
Mean 66.7
Standard deviation 12
Values 58 76
[17]
HepG2.C3A PTPN11
Mean 80.2
Standard deviation 17
Values 68 92
[18]
HuH.7 PTPN11
Mean 74.5
Standard deviation 12
Values 86 77 61
[19]
SNU475 PTPN11
Mean 75.4
Standard deviation 0.72
Values 75 76
[20]
THLE PTPN11
Mean 131
Standard deviation 5.1
Values 1.3e+02 1.3e+02
[21]
liver PTPN11
Mean 75.4
Standard deviation 18
Values 60 99 62 80
[22]
ref_hepatocyte STAT1
Mean 20.3
Standard deviation 8.7
Values 17 35 19 12 18
[23]
HepG2 STAT1
Mean 42.7
Standard deviation 9.4
Values 36 49
[24]
HepG2.C3A STAT1
Mean 20.1
Standard deviation 7.2
Values 15 25
[25]
HuH.7 STAT1
Mean 41.6
Standard deviation 4.5
Values 47 38 40
[26]
SNU475 STAT1
Mean 216
Standard deviation 1.4e+02
Values 3.2e+02 1.1e+02
[27]
THLE STAT1
Mean 50.3
Standard deviation 2.1
Values 49 52
[28]
liver STAT1
Mean 55.8
Standard deviation 15
Values 49 69 67 38
[29]
ref_hepatocyte IFNGR2
Mean 15.8
Standard deviation 5.2
Values 24 15 17 13 9.9
[30]
HepG2 IFNGR2
Mean 34.1
Standard deviation 5.2
Values 38 30
[31]
HepG2.C3A IFNGR2
Mean 44.8
Standard deviation 16
Values 56 33
[32]
HuH.7 IFNGR2
Mean 10.6
Standard deviation 1.9
Values 8.3 12 11
[33]
SNU475 IFNGR2
Mean 11.3
Standard deviation 2.5
Values 13 9.5
[34]
THLE IFNGR2
Mean 30.8
Standard deviation 6.2
Values 26 35
[35]
liver IFNGR2
Mean 15
Standard deviation 7.9
Values 21 7.8 22 8.5
[36]
ref_hepatocyte JAK1
Mean 15.2
Standard deviation 7.8
Values 6.8 27 18 14 10
[37]
HepG2 JAK1
Mean 47.8
Standard deviation 11
Values 40 56
[38]
HepG2.C3A JAK1
Mean 29.8
Standard deviation 1.3
Values 31 29
[39]
HuH.7 JAK1
Mean 32.5
Standard deviation 3.3
Values 36 32 29
[40]
SNU475 JAK1
Mean 43.1
Standard deviation 5.5
Values 47 39
[41]
THLE JAK1
Mean 75.4
Standard deviation 6.9
Values 70 80
[42]
liver JAK1
Mean 62.3
Standard deviation 9.1
Values 54 75 58 62
[43]
ref_hepatocyte SOCS3
Mean 11.2
Standard deviation 10
Values 1 1.5 19 24 10
[44]
HepG2 SOCS3
Mean 1.4
Standard deviation 0.4
Values 1.7 1.1
[45]
HepG2.C3A SOCS3
Mean 0.939
Standard deviation 0.87
Values 1.6 0.32
[46]
HuH.7 SOCS3
Mean 2.97
Standard deviation 2.7
Values 1.4 6.1 1.4
[47]
SNU475 SOCS3
Mean 11.8
Standard deviation 0.67
Values 12 11
[48]
THLE SOCS3
Mean 6.29
Standard deviation 1.1
Values 7.1 5.5
[49]
liver SOCS3
Mean 17.4
Standard deviation 5.5
Values 15 14 15 26
[50]
ref_hepatocyte PTPN1
Mean 8.72
Standard deviation 6.8
Values 20 10 6.8 4.1 2.6
[51]
HepG2 PTPN1
Mean 41.8
Standard deviation 5
Values 38 45
[52]
HepG2.C3A PTPN1
Mean 29.5
Standard deviation 3
Values 27 32
[53]
HuH.7 PTPN1
Mean 20.4
Standard deviation 3.4
Values 24 18 19
[54]
SNU475 PTPN1
Mean 56.7
Standard deviation 1.9
Values 55 58
[55]
THLE PTPN1
Mean 39.1
Standard deviation 7.5
Values 34 44
[56]
liver PTPN1
Mean 10
Standard deviation 0.98
Values 11 10 11 8.6
[57]
ref_hepatocyte PTPN2
Mean 8.27
Standard deviation 3
Values 5 6 9.1 13 8.8
[58]
HepG2 PTPN2
Mean 10.1
Standard deviation 2.9
Values 8 12
[59]
HepG2.C3A PTPN2
Mean 22.3
Standard deviation 0.11
Values 22 22
[60]
HuH.7 PTPN2
Mean 28
Standard deviation 2.9
Values 28 25 31
[61]
SNU475 PTPN2
Mean 10.3
Standard deviation 2
Values 8.9 12
[62]
THLE PTPN2
Mean 12.7
Standard deviation 0.75
Values 12 13
[63]
liver PTPN2
Mean 9.84
Standard deviation 1.6
Values 11 8.1 12 8.9
[64]
ref_hepatocyte PTPN6
Mean 5.33
Standard deviation 3
Values 2.2 3.1 4.4 7.6 9.3
[65]
HepG2 PTPN6
Mean 8.54
Standard deviation 0.054
Values 8.5 8.6
[66]
HepG2.C3A PTPN6
Mean 8.69
Standard deviation 0.18
Values 8.6 8.8
[67]
HuH.7 PTPN6
Mean 12.4
Standard deviation 1.9
Values 13 10 14
[68]
SNU475 PTPN6
Mean 0.0694
Standard deviation 0.026
Values 0.088 0.051
[69]
THLE PTPN6
Mean 2.52
Standard deviation 0.67
Values 2 3
[70]
liver PTPN6
Mean 6.69
Standard deviation 2
Values 7.5 4.8 9.1 5.4
[71]
ref_hepatocyte PIAS1
Mean 2.96
Standard deviation 1.1
Values 2.2 2.9 4.9 2.2 2.7
[72]
HepG2 PIAS1
Mean 6.75
Standard deviation 3.6
Values 4.2 9.3
[73]
HepG2.C3A PIAS1
Mean 7.18
Standard deviation 2
Values 5.7 8.6
[74]
HuH.7 PIAS1
Mean 12.9
Standard deviation 1.7
Values 15 12 12
[75]
SNU475 PIAS1
Mean 9.97
Standard deviation 0.61
Values 10 9.5
[76]
THLE PIAS1
Mean 9.23
Standard deviation 0.13
Values 9.1 9.3
[77]
liver PIAS1
Mean 9.55
Standard deviation 5.5
Values 15 5.5 13 4.3
[78]
ref_hepatocyte SOCS1
Mean 2.1
Standard deviation 1.9
Values 1.1 0 1.3 4.7 3.4
[79]
HepG2 SOCS1
Mean 1.7
Standard deviation 0.19
Values 1.8 1.6
[80]
HepG2.C3A SOCS1
Mean 2.76
Standard deviation 1.3
Values 3.7 1.9
[81]
HuH.7 SOCS1
Mean 3.19
Standard deviation 2.1
Values 3.3 1 5.3
[82]
SNU475 SOCS1
Mean 1.11
Standard deviation 0.23
Values 1.3 0.95
[83]
THLE SOCS1
Mean 0.479
Standard deviation 0.076
Values 0.53 0.43
[84]
liver SOCS1
Mean 1.08
Standard deviation 0.8
Values 1.1 0.27 0.8 2.2
[85]
ref_hepatocyte JAK2
Mean 0.762
Standard deviation 0.48
Values 1.3 1.3 0.62 0.18 0.5
[86]
HepG2 JAK2
Mean 1.97
Standard deviation 1.3
Values 1 2.9
[87]
HepG2.C3A JAK2
Mean 1.75
Standard deviation 0.67
Values 1.3 2.2
[88]
HuH.7 JAK2
Mean 1.23
Standard deviation 0.34
Values 1.2 1.6 0.9
[89]
SNU475 JAK2
Mean 2.37
Standard deviation 0.1
Values 2.3 2.4
[90]
THLE JAK2
Mean 4.02
Standard deviation 0.77
Values 4.6 3.5
[91]
liver JAK2
Mean 7.06
Standard deviation 3.8
Values 4.7 11 2.9 9.8
[92]
ref_hepatocyte IFNG
Mean 0.182
Standard deviation 0.29
Values 0 0 0 0.23 0.67
[93]
HepG2 IFNG
Mean 0
Standard deviation 0
Values 0 0
[94]
HepG2.C3A IFNG
Mean 0
Standard deviation 0
Values 0 0
[95]
HuH.7 IFNG
Mean 0
Standard deviation 0
Values 0 0 0
[96]
SNU475 IFNG
Mean 0.206
Standard deviation 0.22
Values 0.36 0.051
[97]
THLE IFNG
Mean 0
Standard deviation 0
Values 0 0
[98]
liver IFNG
Mean 0.0524
Standard deviation 0.037
Values 0.024 0.057 0.1 0.026