REACTOME_REGULATION_OF_GLYCOLYSIS_BY_FRUCTOSE_2_6_BISPHOSPHATE_METABOLISM Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 PPP2R1A Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform 0.14[1] 0.25[2] 0.21[3] 0.22[4] 0.12[5] -0.48[6]
2 PPP2CA Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform -0.39[7] -0.01[8] -0.60[9] -0.25[10] 0.44[11] -0.73[12]
3 PPP2CB Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform -1.05[13] -1.11[14] -0.99[15] -1.44[16] -0.98[17] -1.61[18]
4 PRKACA cAMP-dependent protein kinase catalytic subunit alpha [19] -0.82[20] -0.71[21] -0.68[22] -1.46[23] -0.30[24] -1.40[25]
5 PPP2R1B Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform -0.21[26] -0.45[27] 0.01[28] -0.72[29] -0.37[30] 2.31[31]
6 PPP2R5D Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform 0.59[32] 0.64[33] 0.23[34] 0.30[35] 0.76[36] -0.89[37]
7 PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 [38] 1.96[39] -0.36[40] -0.16[41] 2.73[42] 0.33[43] -0.95[44]
8 PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 [45] -3.45[46] -2.41[47] -7.49[48] -8.26[49] -8.27[50] -0.25[51]
9 PRKACB cAMP-dependent protein kinase catalytic subunit beta [52] -1.49[53] -0.43[54] 0.89[55] 1.25[56] 0.67[57] 1.09[58]
10 PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 [59] 1.04[60] 1.82[61] 1.16[62] 1.34[63] 0.50[64] 1.26[65]
11 PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 [66] 4.59[67] 4.93[68] 5.43[69] 1.96[70] 2.08[71] -0.28[72]
12 PRKACG cAMP-dependent protein kinase catalytic subunit gamma [73] [74] [75] [76] [77] [78] [79]
[1]
ref_hepatocyte PPP2R1A
Mean 27.9
Standard deviation 5.4
Values 23 30 23 36 28
[2]
HepG2 PPP2R1A
Mean 107
Standard deviation 6.5
Values 1.1e+02 1e+02
[3]
HepG2.C3A PPP2R1A
Mean 84.7
Standard deviation 12
Values 93 76
[4]
HuH.7 PPP2R1A
Mean 77.2
Standard deviation 6.8
Values 84 70 78
[5]
SNU475 PPP2R1A
Mean 118
Standard deviation 14
Values 1.3e+02 1.1e+02
[6]
THLE PPP2R1A
Mean 83.3
Standard deviation 16
Values 72 94
[7]
liver PPP2R1A
Mean 43.9
Standard deviation 17
Values 51 30 65 30
[8]
ref_hepatocyte PPP2CA
Mean 27.3
Standard deviation 6.4
Values 27 38 22 24 25
[9]
HepG2 PPP2CA
Mean 72.8
Standard deviation 15
Values 62 83
[10]
HepG2.C3A PPP2CA
Mean 69.2
Standard deviation 19
Values 55 83
[11]
HuH.7 PPP2CA
Mean 42.8
Standard deviation 4.9
Values 43 38 48
[12]
SNU475 PPP2CA
Mean 83.9
Standard deviation 4.1
Values 81 87
[13]
THLE PPP2CA
Mean 102
Standard deviation 13
Values 92 1.1e+02
[14]
liver PPP2CA
Mean 36.1
Standard deviation 13
Values 49 27 46 23
[15]
ref_hepatocyte PPP2CB
Mean 25.5
Standard deviation 11
Values 15 43 27 17 26
[16]
HepG2 PPP2CB
Mean 43
Standard deviation 1.5
Values 44 42
[17]
HepG2.C3A PPP2CB
Mean 30.2
Standard deviation 0.78
Values 31 30
[18]
HuH.7 PPP2CB
Mean 30.6
Standard deviation 2.8
Values 28 34 30
[19]
SNU475 PPP2CB
Mean 34.2
Standard deviation 0.1
Values 34 34
[20]
THLE PPP2CB
Mean 35.7
Standard deviation 2.6
Values 37 34
[21]
liver PPP2CB
Mean 18.3
Standard deviation 7.2
Values 28 14 19 12
[22]
ref_hepatocyte PRKACA
Mean 15.8
Standard deviation 8.3
Values 7.6 11 11 27 23
[23]
HepG2 PRKACA
Mean 31.2
Standard deviation 2.7
Values 29 33
[24]
HepG2.C3A PRKACA
Mean 24.6
Standard deviation 3.5
Values 27 22
[25]
HuH.7 PRKACA
Mean 23.6
Standard deviation 5.7
Values 27 17 27
[26]
SNU475 PRKACA
Mean 21
Standard deviation 3.3
Values 23 19
[27]
THLE PRKACA
Mean 35.4
Standard deviation 5.3
Values 32 39
[28]
liver PRKACA
Mean 13.1
Standard deviation 4.9
Values 18 8.8 16 8.9
[29]
ref_hepatocyte PPP2R1B
Mean 12
Standard deviation 3.3
Values 7 14 11 15 13
[30]
HepG2 PPP2R1B
Mean 36.3
Standard deviation 12
Values 27 45
[31]
HepG2.C3A PPP2R1B
Mean 22.5
Standard deviation 5.6
Values 19 26
[32]
HuH.7 PPP2R1B
Mean 28.7
Standard deviation 4.1
Values 32 30 24
[33]
SNU475 PPP2R1B
Mean 26.6
Standard deviation 1.2
Values 26 27
[34]
THLE PPP2R1B
Mean 25.6
Standard deviation 5.7
Values 22 30
[35]
liver PPP2R1B
Mean 130
Standard deviation 78
Values 52 1.6e+02 82 2.2e+02
[36]
ref_hepatocyte PPP2R5D
Mean 7.67
Standard deviation 1.8
Values 11 7.4 6.7 6.6 6.7
[37]
HepG2 PPP2R5D
Mean 40.3
Standard deviation 5.9
Values 36 44
[38]
HepG2.C3A PPP2R5D
Mean 30.4
Standard deviation 4.1
Values 27 33
[39]
HuH.7 PPP2R5D
Mean 21.5
Standard deviation 4.4
Values 26 17 22
[40]
SNU475 PPP2R5D
Mean 34.4
Standard deviation 4.8
Values 38 31
[41]
THLE PPP2R5D
Mean 35.6
Standard deviation 5.6
Values 32 40
[42]
liver PPP2R5D
Mean 9.05
Standard deviation 4.1
Values 11 5.8 14 5.4
[43]
ref_hepatocyte PFKFB3
Mean 4.59
Standard deviation 4.4
Values 0.13 3.5 8.2 10 0.97
[44]
HepG2 PFKFB3
Mean 62.1
Standard deviation 5.4
Values 66 58
[45]
HepG2.C3A PFKFB3
Mean 9.1
Standard deviation 1.7
Values 7.9 10
[46]
HuH.7 PFKFB3
Mean 9.78
Standard deviation 0.64
Values 10 10 9.1
[47]
SNU475 PFKFB3
Mean 111
Standard deviation 22
Values 1.3e+02 95
[48]
THLE PFKFB3
Mean 15.8
Standard deviation 0.036
Values 16 16
[49]
liver PFKFB3
Mean 5.17
Standard deviation 2.7
Values 2.3 7.3 3.4 7.7
[50]
ref_hepatocyte PFKFB1
Mean 4.06
Standard deviation 5.2
Values 0.48 0.81 0.82 5.6 13
[51]
HepG2 PFKFB1
Mean 1.3
Standard deviation 0.56
Values 0.9 1.7
[52]
HepG2.C3A PFKFB1
Mean 1.94
Standard deviation 0.031
Values 2 1.9
[53]
HuH.7 PFKFB1
Mean 0.0538
Standard deviation 0.039
Values 0.016 0.051 0.094
[54]
SNU475 PFKFB1
Mean 0.0483
Standard deviation 0.0038
Values 0.051 0.046
[55]
THLE PFKFB1
Mean 0.0361
Standard deviation 0.0092
Values 0.03 0.043
[56]
liver PFKFB1
Mean 7.44
Standard deviation 2.6
Values 7.4 5.4 5.9 11
[57]
ref_hepatocyte PRKACB
Mean 2.75
Standard deviation 1.3
Values 2.1 3.1 1.4 2.4 4.8
[58]
HepG2 PRKACB
Mean 3.41
Standard deviation 1.6
Values 2.3 4.6
[59]
HepG2.C3A PRKACB
Mean 5.2
Standard deviation 0.9
Values 4.6 5.8
[60]
HuH.7 PRKACB
Mean 12.2
Standard deviation 3.4
Values 11 16 9.5
[61]
SNU475 PRKACB
Mean 23.8
Standard deviation 4.4
Values 27 21
[62]
THLE PRKACB
Mean 12.1
Standard deviation 0.96
Values 13 11
[63]
liver PRKACB
Mean 12.8
Standard deviation 2
Values 12 14 14 10
[64]
ref_hepatocyte PFKFB2
Mean 1.12
Standard deviation 1.1
Values 3.1 1.1 0.51 0.47 0.46
[65]
HepG2 PFKFB2
Mean 7.99
Standard deviation 2.8
Values 6 10
[66]
HepG2.C3A PFKFB2
Mean 10
Standard deviation 1.3
Values 11 9.1
[67]
HuH.7 PFKFB2
Mean 5.95
Standard deviation 2
Values 5.3 8.2 4.4
[68]
SNU475 PFKFB2
Mean 10.3
Standard deviation 3.8
Values 13 7.6
[69]
THLE PFKFB2
Mean 4.33
Standard deviation 0.68
Values 3.8 4.8
[70]
liver PFKFB2
Mean 5.83
Standard deviation 3.5
Values 2.2 10 3.9 7.2
[71]
ref_hepatocyte PFKFB4
Mean 0.54
Standard deviation 0.67
Values 1.7 0.1 0.25 0.45 0.19
[72]
HepG2 PFKFB4
Mean 45.5
Standard deviation 9.5
Values 39 52
[73]
HepG2.C3A PFKFB4
Mean 42
Standard deviation 12
Values 51 33
[74]
HuH.7 PFKFB4
Mean 55.6
Standard deviation 10
Values 47 67 53
[75]
SNU475 PFKFB4
Mean 7.66
Standard deviation 0.44
Values 7.4 8
[76]
THLE PFKFB4
Mean 6.27
Standard deviation 1.8
Values 7.6 5
[77]
liver PFKFB4
Mean 0.973
Standard deviation 0.3
Values 0.61 0.84 1.2 1.3
[78]
ref_hepatocyte PRKACG
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[79]
HepG2 PRKACG
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[80]
HepG2.C3A PRKACG
Mean 0
Standard deviation 0
Values 0 0
[81]
HuH.7 PRKACG
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[82]
SNU475 PRKACG
Mean 0
Standard deviation 0
Values 0 0
[83]
THLE PRKACG
Mean 0
Standard deviation 0
Values 0 0
[84]
liver PRKACG
Mean 0
Standard deviation 0
Values 0 0 0 0