REACTOME_REGULATION_OF_COMMISSURAL_AXON_PATHFINDING_BY_SLIT_AND_ROBO Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 SRC Proto-oncogene tyrosine-protein kinase Src [1] 0.29[2] 0.08[3] 0.08[4] -0.40[5] -0.30[6] -1.56[7]
2 ROBO1 Roundabout homolog 1 [8] 0.04[9] 0.28[10] 0.00[11] -1.29[12] -0.23[13] -0.82[14]
3 NTN1 Netrin-1 [15] -4.89[16] -5.77[17] -1.20[18] -7.45[19] -4.24[20] 2.56[21]
4 ROBO3 Roundabout homolog 3 [22] -3.72[23] -5.85[24] [25] -3.23[26] -0.20[27] -0.13[28]
5 NELL2 Protein kinase C-binding protein NELL2 [29] -6.95[30] [31] -0.90[32] -5.73[33] -3.39[34] -1.84[35]
6 SLIT2 Slit homolog 2 protein [36] -3.97[37] -8.11[38] -2.12[39] -0.62[40] -0.22[41] 2.28[42]
7 SLIT3 Slit homolog 3 protein [43] -1.38[44] -0.39[45] 0.18[46] 8.86[47] 7.83[48] 6.31[49]
8 SLIT1 Slit homolog 1 protein [50] -0.95[51] 0.99[52] 2.59[53] -0.97[54] -0.18[55] 4.16[56]
9 ROBO2 Roundabout homolog 2 [57] -5.11[58] [59] 6.27[60] -2.74[61] -1.49[62] 5.51[63]
10 DCC Netrin receptor DCC [64] [65] [66] [67] [68] [69] [70]
[1]
ref_hepatocyte SRC
Mean 3.67
Standard deviation 3.6
Values 9.6 4.7 2.2 0.77 1.2
[2]
HepG2 SRC
Mean 66
Standard deviation 21
Values 81 51
[3]
HepG2.C3A SRC
Mean 58.1
Standard deviation 18
Values 71 45
[4]
HuH.7 SRC
Mean 27.9
Standard deviation 2
Values 28 29 26
[5]
SNU475 SRC
Mean 35.6
Standard deviation 3.5
Values 38 33
[6]
THLE SRC
Mean 22.5
Standard deviation 2.7
Values 21 24
[7]
liver SRC
Mean 2.9
Standard deviation 1
Values 4.1 2.5 1.7 3.2
[8]
ref_hepatocyte ROBO1
Mean 3.39
Standard deviation 7.3
Values 16 0.016 0.41 0.043 0.13
[9]
HepG2 ROBO1
Mean 51
Standard deviation 6.3
Values 47 55
[10]
HepG2.C3A ROBO1
Mean 61.4
Standard deviation 6.1
Values 66 57
[11]
HuH.7 ROBO1
Mean 24.4
Standard deviation 5.9
Values 26 29 18
[12]
SNU475 ROBO1
Mean 17.7
Standard deviation 2.6
Values 20 16
[13]
THLE ROBO1
Mean 21.8
Standard deviation 6
Values 18 26
[14]
liver ROBO1
Mean 4.47
Standard deviation 1.3
Values 3.4 5.7 3.3 5.6
[15]
ref_hepatocyte NTN1
Mean 0.538
Standard deviation 0.57
Values 0 0.22 0.55 1.5 0.45
[16]
HepG2 NTN1
Mean 0.266
Standard deviation 0.22
Values 0.42 0.11
[17]
HepG2.C3A NTN1
Mean 0.147
Standard deviation 0.011
Values 0.16 0.14
[18]
HuH.7 NTN1
Mean 1.68
Standard deviation 0.15
Values 1.6 1.9 1.6
[19]
SNU475 NTN1
Mean 0.0393
Standard deviation 0.016
Values 0.028 0.051
[20]
THLE NTN1
Mean 0.215
Standard deviation 0.056
Values 0.25 0.18
[21]
liver NTN1
Mean 7.41
Standard deviation 5
Values 3.7 13 2.8 9.9
[22]
ref_hepatocyte ROBO3
Mean 0.193
Standard deviation 0.3
Values 0 0 0.71 0.13 0.12
[23]
HepG2 ROBO3
Mean 0.215
Standard deviation 0.085
Values 0.28 0.15
[24]
HepG2.C3A ROBO3
Mean 0.0501
Standard deviation 0.025
Values 0.068 0.032
[25]
HuH.7 ROBO3
Mean 0
Standard deviation 0
Values 0 0 0
[26]
SNU475 ROBO3
Mean 0.263
Standard deviation 0.12
Values 0.18 0.35
[27]
THLE ROBO3
Mean 1.27
Standard deviation 0.28
Values 1.5 1.1
[28]
liver ROBO3
Mean 0.412
Standard deviation 0.16
Values 0.56 0.37 0.51 0.2
[29]
ref_hepatocyte NELL2
Mean 0.115
Standard deviation 0.16
Values 0 0 0.37 0.052 0.15
[30]
HepG2 NELL2
Mean 0.0136
Standard deviation 0.013
Values 0.023 0.0043
[31]
HepG2.C3A NELL2
Mean 0
Standard deviation 0
Values 0 0
[32]
HuH.7 NELL2
Mean 0.442
Standard deviation 0.13
Values 0.3 0.56 0.46
[33]
SNU475 NELL2
Mean 0.0277
Standard deviation 0.033
Values 0.0046 0.051
[34]
THLE NELL2
Mean 0.0825
Standard deviation 0.034
Values 0.11 0.059
[35]
liver NELL2
Mean 0.0747
Standard deviation 0.079
Values 0.047 0.19 0 0.066
[36]
ref_hepatocyte SLIT2
Mean 0.099
Standard deviation 0.14
Values 0 0.21 0.28 0 0
[37]
HepG2 SLIT2
Mean 0.0923
Standard deviation 0.04
Values 0.12 0.064
[38]
HepG2.C3A SLIT2
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[39]
HuH.7 SLIT2
Mean 0.164
Standard deviation 0.11
Values 0.082 0.29 0.12
[40]
SNU475 SLIT2
Mean 0.824
Standard deviation 0.57
Values 0.42 1.2
[41]
THLE SLIT2
Mean 0.639
Standard deviation 0.075
Values 0.59 0.69
[42]
liver SLIT2
Mean 1.12
Standard deviation 0.57
Values 0.63 1.2 0.74 1.9
[43]
ref_hepatocyte SLIT3
Mean 0.00813
Standard deviation 0.018
Values 0 0 0 0 0.041
[44]
HepG2 SLIT3
Mean 0.0458
Standard deviation 0.041
Values 0.074 0.017
[45]
HepG2.C3A SLIT3
Mean 0.093
Standard deviation 0.035
Values 0.068 0.12
[46]
HuH.7 SLIT3
Mean 0.0663
Standard deviation 0.041
Values 0.09 0.09 0.019
[47]
SNU475 SLIT3
Mean 48.1
Standard deviation 37
Values 74 22
[48]
THLE SLIT3
Mean 13.9
Standard deviation 6.4
Values 9.4 18
[49]
liver SLIT3
Mean 1.5
Standard deviation 0.37
Values 1.2 1.5 1.3 2
[50]
ref_hepatocyte SLIT1
Mean 0.00612
Standard deviation 0.014
Values 0.031 0 0 0 0
[51]
HepG2 SLIT1
Mean 0.0465
Standard deviation 0.023
Values 0.063 0.03
[52]
HepG2.C3A SLIT1
Mean 0.182
Standard deviation 0.06
Values 0.22 0.14
[53]
HuH.7 SLIT1
Mean 0.265
Standard deviation 0.12
Values 0.34 0.12 0.33
[54]
SNU475 SLIT1
Mean 0.0399
Standard deviation 0.037
Values 0.014 0.066
[55]
THLE SLIT1
Mean 0.0408
Standard deviation 0.033
Values 0.018 0.064
[56]
liver SLIT1
Mean 0.255
Standard deviation 0.16
Values 0.28 0.17 0.1 0.46
[57]
ref_hepatocyte ROBO2
Mean 0.00507
Standard deviation 0.0077
Values 0 0 0 0.017 0.0081
[58]
HepG2 ROBO2
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[59]
HepG2.C3A ROBO2
Mean 0
Standard deviation 0
Values 0 0
[60]
HuH.7 ROBO2
Mean 2.82
Standard deviation 2.7
Values 1.6 5.9 0.9
[61]
SNU475 ROBO2
Mean 0.00971
Standard deviation 0.00061
Values 0.0093 0.01
[62]
THLE ROBO2
Mean 0.0136
Standard deviation 0.011
Values 0.0059 0.021
[63]
liver ROBO2
Mean 0.537
Standard deviation 0.38
Values 0.33 0.7 0.13 0.99
[64]
ref_hepatocyte DCC
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[65]
HepG2 DCC
Mean 0
Standard deviation 0
Values 0 0
[66]
HepG2.C3A DCC
Mean 0
Standard deviation 0
Values 0 0
[67]
HuH.7 DCC
Mean 0
Standard deviation 0
Values 0 0 0
[68]
SNU475 DCC
Mean 0.0228
Standard deviation 0.032
Values 0 0.046
[69]
THLE DCC
Mean 0
Standard deviation 0
Values 0 0
[70]
liver DCC
Mean 0.0171
Standard deviation 0.02
Values 0 0.029 0 0.04