REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 SLC2A2 Solute carrier family 2, facilitated glucose transporter member 2 [1] -3.39[2] -2.77[3] -2.39[4] -6.59[5] -10.88[6] 0.61[7]
2 AKT1 RAC-alpha serine/threonine-protein kinase [8] -0.11[9] -0.50[10] -1.85[11] 0.13[12] 0.23[13] -1.47[14]
3 SNW1 SNW domain-containing protein 1 [15] -1.19[16] -1.18[17] -1.43[18] 0.05[19] -0.12[20] -2.86[21]
4 HNF4A Hepatocyte nuclear factor 4-alpha [22] 0.90[23] 1.21[24] 0.84[25] -6.83[26] -7.38[27] 0.61[28]
5 FOXA3 Hepatocyte nuclear factor 3-gamma [29] -1.26[30] -0.25[31] -0.03[32] -7.31[33] -8.22[34] -2.26[35]
6 AKT2 RAC-beta serine/threonine-protein kinase [36] 0.77[37] 0.89[38] 0.74[39] 1.04[40] 0.91[41] -0.10[42]
7 FOXA2 Hepatocyte nuclear factor 3-beta [43] 0.32[44] 0.47[45] 0.60[46] -7.36[47] -7.91[48] -1.71[49]
8 PKLR Pyruvate kinase PKLR [50] -2.06[51] -0.34[52] -2.34[53] -9.99[54] -9.81[55] -0.27[56]
9 HES1 Transcription factor HES-1 [57] -0.62[58] -3.28[59] -1.30[60] -1.09[61] -1.84[62] -2.63[63]
10 HNF1A Hepatocyte nuclear factor 1-alpha [64] 0.72[65] 0.89[66] 1.31[67] -3.19[68] -3.96[69] -1.03[70]
11 KAT2A Histone acetyltransferase KAT2A [71] 1.84[72] 1.54[73] 0.38[74] 1.31[75] 1.24[76] -0.95[77]
12 RBPJ Recombining binding protein suppressor of hairless [78] 1.15[79] 1.57[80] 2.30[81] 2.20[82] 2.22[83] 0.63[84]
13 KAT2B Histone acetyltransferase KAT2B [85] -2.24[86] -3.51[87] -1.42[88] 0.12[89] 0.62[90] 0.56[91]
14 NR5A2 Nuclear receptor subfamily 5 group A member 2 [92] -4.07[93] -3.94[94] 1.31[95] -4.01[96] 0.40[97] 1.54[98]
15 EP300 Histone acetyltransferase p300 [99] 2.53[100] 1.97[101] 2.59[102] 2.75[103] 2.89[104] 1.53[105]
16 MAML1 Mastermind-like protein 1 [106] 1.93[107] 1.73[108] 2.00[109] 2.43[110] 2.64[111] -0.15[112]
17 HNF1B Hepatocyte nuclear factor 1-beta [113] -0.38[114] -2.84[115] 1.00[116] -0.66[117] -7.00[118] -1.03[119]
18 HNF4G Hepatocyte nuclear factor 4-gamma [120] -1.14[121] 1.32[122] 1.22[123] -0.57[124] -5.82[125] 0.51[126]
19 CREBBP CREB-binding protein [127] 2.71[128] 1.77[129] 2.10[130] 2.94[131] 3.03[132] 2.01[133]
20 FOXO1 Forkhead box protein O1 [134] 1.50[135] 1.01[136] 0.87[137] 1.36[138] 3.46[139] 1.86[140]
21 ONECUT1 Hepatocyte nuclear factor 6 [141] -1.18[142] -0.22[143] 2.33[144] -7.54[145] -6.20[146] 1.84[147]
22 MAMLD1 Mastermind-like domain-containing protein 1 [148] -2.09[149] -8.74[150] -2.77[151] 1.24[152] 1.14[153] -1.56[154]
23 NOTCH1 Neurogenic locus notch homolog protein 1 [155] 1.72[156] 0.40[157] 1.46[158] 2.77[159] 3.20[160] 3.41[161]
24 GCK Glucokinase [162] -8.14[163] -6.30[164] -9.77[165] -6.74[166] -4.71[167] 0.70[168]
25 MAML3 Mastermind-like protein 3 [169] -0.56[170] 0.01[171] 2.77[172] 1.58[173] 0.28[174] 2.27[175]
26 AKT3 RAC-gamma serine/threonine-protein kinase [176] -2.03[177] -4.75[178] -4.34[179] 6.02[180] 5.06[181] 2.38[182]
27 IAPP Islet amyloid polypeptide [183] -2.07[184] -1.52[185] -1.62[186] -1.73[187] -1.57[188] -2.69[189]
28 MAML2 Mastermind-like protein 2 [190] 3.30[191] 3.76[192] -3.08[193] 4.96[194] 3.91[195] 1.13[196]
29 MAFA Transcription factor MafA [197] 0.23[198] -1.58[199] -1.13[200] -3.25[201] -1.16[202] [203]
30 PAX6 Paired box protein Pax-6 [204] 5.48[205] 3.65[206] 5.04[207] 4.94[208] 1.86[209] 1.13[210]
31 PDX1 Pancreas/duodenum homeobox protein 1 [211] 0.21[212] -2.63[213] 5.00[214] -2.08[215] [216] 1.21[217]
32 NKX2-2 Homeobox protein Nkx-2.2 [218] [219] [220] [221] [222] [223] [224]
33 NEUROG3 Neurogenin-3 [225] [226] [227] [228] [229] [230] [231]
34 RFX6 DNA-binding protein RFX6 [232] [233] [234] [235] [236] [237] [238]
35 INS Insulin [239] [240] [241] [242] [243] [244] [245]
36 PTF1A Pancreas transcription factor 1 subunit alpha [246] [247] [248] [249] [250] [251] [252]
37 INSM1 Insulinoma-associated protein 1 [253] [254] [255] [256] [257] [258] [259]
38 PAX4 Paired box protein Pax-4 [260] [261] [262] [263] [264] [265] [266]
39 NKX6-1 Homeobox protein Nkx-6.1 [267] [268] [269] [270] [271] [272] [273]
40 ONECUT3 One cut domain family member 3 [274] [275] [276] [277] [278] [279] [280]
41 FGF10 Fibroblast growth factor 10 [281] [282] [283] [284] [285] [286] [287]
42 NEUROD1 Neurogenic differentiation factor 1 [288] [289] [290] [291] [292] [293] [294]
[1]
ref_hepatocyte SLC2A2
Mean 50.4
Standard deviation 77
Values 3.6 23 0.5 39 1.9e+02
[2]
HepG2 SLC2A2
Mean 12.1
Standard deviation 6.3
Values 7.6 17
[3]
HepG2.C3A SLC2A2
Mean 18.4
Standard deviation 9.8
Values 11 25
[4]
HuH.7 SLC2A2
Mean 27.9
Standard deviation 5.4
Values 29 32 22
[5]
SNU475 SLC2A2
Mean 0.843
Standard deviation 0.21
Values 0.99 0.69
[6]
THLE SLC2A2
Mean 0.0458
Standard deviation 0.027
Values 0.065 0.027
[7]
liver SLC2A2
Mean 257
Standard deviation 32
Values 2.5e+02 2.6e+02 2.2e+02 2.9e+02
[8]
ref_hepatocyte AKT1
Mean 37.6
Standard deviation 15
Values 55 50 19 31 32
[9]
HepG2 AKT1
Mean 87.8
Standard deviation 2.3
Values 89 86
[10]
HepG2.C3A AKT1
Mean 66.6
Standard deviation 2.4
Values 65 68
[11]
HuH.7 AKT1
Mean 30.2
Standard deviation 6.6
Values 33 23 35
[12]
SNU475 AKT1
Mean 66.6
Standard deviation 14
Values 76 57
[13]
THLE AKT1
Mean 75.8
Standard deviation 6.1
Values 72 80
[14]
liver AKT1
Mean 45.1
Standard deviation 25
Values 34 48 20 79
[15]
ref_hepatocyte SNW1
Mean 24.9
Standard deviation 12
Values 34 38 27 15 9.7
[16]
HepG2 SNW1
Mean 27.5
Standard deviation 2.9
Values 25 29
[17]
HepG2.C3A SNW1
Mean 27.5
Standard deviation 0.76
Values 27 28
[18]
HuH.7 SNW1
Mean 26.8
Standard deviation 1.3
Values 26 26 28
[19]
SNU475 SNW1
Mean 41.5
Standard deviation 3.1
Values 39 44
[20]
THLE SNW1
Mean 39.4
Standard deviation 2.3
Values 38 41
[21]
liver SNW1
Mean 11.4
Standard deviation 4.1
Values 14 9.2 15 6.8
[22]
ref_hepatocyte HNF4A
Mean 22.2
Standard deviation 11
Values 30 11 9.6 30 30
[23]
HepG2 HNF4A
Mean 104
Standard deviation 5.9
Values 1e+02 1.1e+02
[24]
HepG2.C3A HNF4A
Mean 128
Standard deviation 15
Values 1.4e+02 1.2e+02
[25]
HuH.7 HNF4A
Mean 115
Standard deviation 13
Values 1.2e+02 1.2e+02 1e+02
[26]
SNU475 HNF4A
Mean 0.314
Standard deviation 0.14
Values 0.21 0.42
[27]
THLE HNF4A
Mean 0.228
Standard deviation 0.1
Values 0.3 0.15
[28]
liver HNF4A
Mean 113
Standard deviation 8.7
Values 1.2e+02 1.1e+02 1e+02 1.2e+02
[29]
ref_hepatocyte FOXA3
Mean 12.4
Standard deviation 15
Values 0.59 1.2 5.3 18 37
[30]
HepG2 FOXA3
Mean 13
Standard deviation 1.4
Values 12 14
[31]
HepG2.C3A FOXA3
Mean 26.1
Standard deviation 5.7
Values 30 22
[32]
HuH.7 FOXA3
Mean 35.3
Standard deviation 3
Values 33 38 35
[33]
SNU475 FOXA3
Mean 0.126
Standard deviation 0.087
Values 0.065 0.19
[34]
THLE FOXA3
Mean 0.0713
Standard deviation 0.033
Values 0.095 0.048
[35]
liver FOXA3
Mean 8.61
Standard deviation 3.6
Values 10 6.9 13 4.6
[36]
ref_hepatocyte AKT2
Mean 10.6
Standard deviation 2.8
Values 7.2 8.4 11 13 14
[37]
HepG2 AKT2
Mean 45.6
Standard deviation 3.3
Values 48 43
[38]
HepG2.C3A AKT2
Mean 49.1
Standard deviation 8.9
Values 55 43
[39]
HuH.7 AKT2
Mean 51.5
Standard deviation 9.8
Values 59 41 55
[40]
SNU475 AKT2
Mean 35.3
Standard deviation 5.9
Values 39 31
[41]
THLE AKT2
Mean 34.2
Standard deviation 3.5
Values 32 37
[42]
liver AKT2
Mean 33
Standard deviation 9.4
Values 24 36 27 45
[43]
ref_hepatocyte FOXA2
Mean 7.53
Standard deviation 2.5
Values 7.1 4.1 8.6 11 6.8
[44]
HepG2 FOXA2
Mean 23.7
Standard deviation 12
Values 32 15
[45]
HepG2.C3A FOXA2
Mean 26.1
Standard deviation 10
Values 33 19
[46]
HuH.7 FOXA2
Mean 33.3
Standard deviation 2.6
Values 31 36 33
[47]
SNU475 FOXA2
Mean 0.074
Standard deviation 0.033
Values 0.097 0.051
[48]
THLE FOXA2
Mean 0.0538
Standard deviation 0.016
Values 0.065 0.043
[49]
liver FOXA2
Mean 7.66
Standard deviation 5
Values 15 3.8 6.3 5.6
[50]
ref_hepatocyte PKLR
Mean 7.45
Standard deviation 8
Values 8.4 0.078 0.38 8.7 20
[51]
HepG2 PKLR
Mean 4.51
Standard deviation 1.3
Values 3.6 5.4
[52]
HepG2.C3A PKLR
Mean 14.7
Standard deviation 7.4
Values 20 9.5
[53]
HuH.7 PKLR
Mean 4.29
Standard deviation 1.9
Values 3.3 6.5 3.1
[54]
SNU475 PKLR
Mean 0.0118
Standard deviation 0.0095
Values 0.019 0.0051
[55]
THLE PKLR
Mean 0.0142
Standard deviation 0.005
Values 0.018 0.011
[56]
liver PKLR
Mean 20.6
Standard deviation 18
Values 46 5 9.8 22
[57]
ref_hepatocyte HES1
Mean 7.15
Standard deviation 5.3
Values 9.1 1 3.7 15 7
[58]
HepG2 HES1
Mean 11.7
Standard deviation 5.7
Values 16 7.7
[59]
HepG2.C3A HES1
Mean 1.84
Standard deviation 0.56
Values 2.2 1.4
[60]
HuH.7 HES1
Mean 8.41
Standard deviation 1.4
Values 6.9 8.7 9.7
[61]
SNU475 HES1
Mean 5.42
Standard deviation 0.41
Values 5.7 5.1
[62]
THLE HES1
Mean 3.42
Standard deviation 0.023
Values 3.4 3.4
[63]
liver HES1
Mean 3.86
Standard deviation 1.7
Values 6.2 3 4.1 2.2
[64]
ref_hepatocyte HNF1A
Mean 5.57
Standard deviation 2.4
Values 3.4 2.6 7.8 6.4 7.6
[65]
HepG2 HNF1A
Mean 23.2
Standard deviation 1.9
Values 24 22
[66]
HepG2.C3A HNF1A
Mean 25.8
Standard deviation 0.61
Values 26 25
[67]
HuH.7 HNF1A
Mean 40
Standard deviation 1.9
Values 38 41 41
[68]
SNU475 HNF1A
Mean 0.99
Standard deviation 0.31
Values 1.2 0.77
[69]
THLE HNF1A
Mean 0.614
Standard deviation 0.01
Values 0.62 0.61
[70]
liver HNF1A
Mean 9.06
Standard deviation 1.3
Values 9.8 7.4 10 8.6
[71]
ref_hepatocyte KAT2A
Mean 4.96
Standard deviation 1.9
Values 2.4 3.8 6.7 6.8 5
[72]
HepG2 KAT2A
Mean 44.7
Standard deviation 6.9
Values 40 50
[73]
HepG2.C3A KAT2A
Mean 36.2
Standard deviation 5
Values 40 33
[74]
HuH.7 KAT2A
Mean 18.7
Standard deviation 8
Values 18 11 27
[75]
SNU475 KAT2A
Mean 19.9
Standard deviation 2.9
Values 18 22
[76]
THLE KAT2A
Mean 20.1
Standard deviation 3.5
Values 23 18
[77]
liver KAT2A
Mean 8.57
Standard deviation 1.6
Values 9.3 6.8 11 7.7
[78]
ref_hepatocyte RBPJ
Mean 3.53
Standard deviation 1.3
Values 5.4 3.5 3.8 2.1 2.8
[79]
HepG2 RBPJ
Mean 19.7
Standard deviation 8.2
Values 14 26
[80]
HepG2.C3A RBPJ
Mean 26.2
Standard deviation 1.4
Values 25 27
[81]
HuH.7 RBPJ
Mean 50.4
Standard deviation 6.7
Values 58 49 45
[82]
SNU475 RBPJ
Mean 26.3
Standard deviation 0.26
Values 26 26
[83]
THLE RBPJ
Mean 28.1
Standard deviation 3.7
Values 26 31
[84]
liver RBPJ
Mean 18.1
Standard deviation 2.4
Values 21 19 17 16
[85]
ref_hepatocyte KAT2B
Mean 3.02
Standard deviation 2.4
Values 0.53 4.6 0.74 3.2 6.1
[86]
HepG2 KAT2B
Mean 1.62
Standard deviation 1.1
Values 0.84 2.4
[87]
HepG2.C3A KAT2B
Mean 0.662
Standard deviation 0.012
Values 0.67 0.65
[88]
HuH.7 KAT2B
Mean 3.28
Standard deviation 0.41
Values 2.8 3.6 3.4
[89]
SNU475 KAT2B
Mean 5.31
Standard deviation 1.3
Values 6.2 4.4
[90]
THLE KAT2B
Mean 7.98
Standard deviation 1.1
Values 7.2 8.8
[91]
liver KAT2B
Mean 14.8
Standard deviation 5
Values 19 17 7.6 16
[92]
ref_hepatocyte NR5A2
Mean 2.95
Standard deviation 1.8
Values 0.12 4.2 2.1 4 4.3
[93]
HepG2 NR5A2
Mean 0.442
Standard deviation 0.21
Values 0.29 0.59
[94]
HepG2.C3A NR5A2
Mean 0.482
Standard deviation 0.23
Values 0.64 0.32
[95]
HuH.7 NR5A2
Mean 21.3
Standard deviation 11
Values 17 34 13
[96]
SNU475 NR5A2
Mean 0.296
Standard deviation 0.025
Values 0.28 0.31
[97]
THLE NR5A2
Mean 6.69
Standard deviation 1.7
Values 5.5 7.9
[98]
liver NR5A2
Mean 28.7
Standard deviation 5.9
Values 37 28 24 26
[99]
ref_hepatocyte EP300
Mean 2.46
Standard deviation 1.2
Values 3 1.8 4.4 1.4 1.8
[100]
HepG2 EP300
Mean 35.9
Standard deviation 5.7
Values 32 40
[101]
HepG2.C3A EP300
Mean 24.1
Standard deviation 1.4
Values 23 25
[102]
HuH.7 EP300
Mean 43
Standard deviation 15
Values 55 48 26
[103]
SNU475 EP300
Mean 26.9
Standard deviation 1.3
Values 28 26
[104]
THLE EP300
Mean 31.2
Standard deviation 11
Values 23 39
[105]
liver EP300
Mean 23.6
Standard deviation 8
Values 20 27 15 33
[106]
ref_hepatocyte MAML1
Mean 2.18
Standard deviation 1.5
Values 4.8 1.9 2.1 1.1 1
[107]
HepG2 MAML1
Mean 20.9
Standard deviation 0.74
Values 20 21
[108]
HepG2.C3A MAML1
Mean 18.1
Standard deviation 1.4
Values 19 17
[109]
HuH.7 MAML1
Mean 25.3
Standard deviation 3.3
Values 29 23 24
[110]
SNU475 MAML1
Mean 19
Standard deviation 0.56
Values 19 19
[111]
THLE MAML1
Mean 23.3
Standard deviation 2.6
Values 21 25
[112]
liver MAML1
Mean 6.56
Standard deviation 1.8
Values 6 5.9 5.1 9.3
[113]
ref_hepatocyte HNF1B
Mean 2.16
Standard deviation 1.2
Values 0.97 1.2 4.1 2.6 2
[114]
HepG2 HNF1B
Mean 4.18
Standard deviation 0.91
Values 3.5 4.8
[115]
HepG2.C3A HNF1B
Mean 0.755
Standard deviation 0.14
Values 0.86 0.65
[116]
HuH.7 HNF1B
Mean 12.5
Standard deviation 0.66
Values 13 13 12
[117]
SNU475 HNF1B
Mean 2.21
Standard deviation 1.2
Values 3.1 1.3
[118]
THLE HNF1B
Mean 0.029
Standard deviation 0.026
Values 0.047 0.011
[119]
liver HNF1B
Mean 3.51
Standard deviation 2.7
Values 6 1.2 5.6 1.3
[120]
ref_hepatocyte HNF4G
Mean 2.02
Standard deviation 1.6
Values 1.8 1.1 4.8 1.4 1
[121]
HepG2 HNF4G
Mean 2.3
Standard deviation 0.24
Values 2.1 2.5
[122]
HepG2.C3A HNF4G
Mean 12.6
Standard deviation 0.36
Values 12 13
[123]
HuH.7 HNF4G
Mean 13.7
Standard deviation 4.6
Values 12 19 9.9
[124]
SNU475 HNF4G
Mean 2.21
Standard deviation 1.1
Values 3 1.4
[125]
THLE HNF4G
Mean 0.0612
Standard deviation 0.011
Values 0.053 0.069
[126]
liver HNF4G
Mean 9.62
Standard deviation 3.1
Values 7.3 13 7 11
[127]
ref_hepatocyte CREBBP
Mean 1.78
Standard deviation 0.69
Values 1.8 0.72 2.6 1.9 1.9
[128]
HepG2 CREBBP
Mean 29.3
Standard deviation 2.8
Values 27 31
[129]
HepG2.C3A CREBBP
Mean 15.2
Standard deviation 1
Values 16 14
[130]
HuH.7 CREBBP
Mean 22.2
Standard deviation 7.2
Values 28 24 14
[131]
SNU475 CREBBP
Mean 22.1
Standard deviation 0.2
Values 22 22
[132]
THLE CREBBP
Mean 24.9
Standard deviation 7.3
Values 20 30
[133]
liver CREBBP
Mean 23.8
Standard deviation 6
Values 30 21 17 28
[134]
ref_hepatocyte FOXO1
Mean 1.77
Standard deviation 0.68
Values 0.71 1.7 2 1.9 2.6
[135]
HepG2 FOXO1
Mean 12.6
Standard deviation 1.8
Values 11 14
[136]
HepG2.C3A FOXO1
Mean 8.92
Standard deviation 1.5
Values 10 7.9
[137]
HuH.7 FOXO1
Mean 9.41
Standard deviation 1.6
Values 10 10 7.6
[138]
SNU475 FOXO1
Mean 7.33
Standard deviation 1.8
Values 8.6 6
[139]
THLE FOXO1
Mean 33.2
Standard deviation 1.9
Values 32 35
[140]
liver FOXO1
Mean 21.4
Standard deviation 7
Values 25 19 13 29
[141]
ref_hepatocyte ONECUT1
Mean 1.06
Standard deviation 0.6
Values 1.1 0.85 0.18 1.5 1.7
[142]
HepG2 ONECUT1
Mean 1.19
Standard deviation 0.62
Values 0.75 1.6
[143]
HepG2.C3A ONECUT1
Mean 2.29
Standard deviation 0.26
Values 2.1 2.5
[144]
HuH.7 ONECUT1
Mean 15.6
Standard deviation 12
Values 14 28 4.7
[145]
SNU475 ONECUT1
Mean 0.00928
Standard deviation 0.013
Values 0.019 0
[146]
THLE ONECUT1
Mean 0.0248
Standard deviation 0.01
Values 0.018 0.032
[147]
liver ONECUT1
Mean 12.7
Standard deviation 2
Values 12 15 10 13
[148]
ref_hepatocyte MAMLD1
Mean 0.833
Standard deviation 1.1
Values 0 0.39 2.7 0.16 0.94
[149]
HepG2 MAMLD1
Mean 0.493
Standard deviation 0.22
Values 0.34 0.65
[150]
HepG2.C3A MAMLD1
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[151]
HuH.7 MAMLD1
Mean 0.356
Standard deviation 0.046
Values 0.31 0.35 0.4
[152]
SNU475 MAMLD1
Mean 3.17
Standard deviation 0.79
Values 2.6 3.7
[153]
THLE MAMLD1
Mean 3.14
Standard deviation 0.38
Values 3.4 2.9
[154]
liver MAMLD1
Mean 0.94
Standard deviation 0.39
Values 1.1 0.64 1.4 0.62
[155]
ref_hepatocyte NOTCH1
Mean 0.644
Standard deviation 0.25
Values 0.33 0.55 0.55 0.91 0.89
[156]
HepG2 NOTCH1
Mean 5.33
Standard deviation 3.7
Values 8 2.7
[157]
HepG2.C3A NOTCH1
Mean 2.12
Standard deviation 0.1
Values 2.1 2.2
[158]
HuH.7 NOTCH1
Mean 5.14
Standard deviation 1.4
Values 5.4 6.4 3.6
[159]
SNU475 NOTCH1
Mean 7.09
Standard deviation 0.64
Values 6.6 7.5
[160]
THLE NOTCH1
Mean 10.2
Standard deviation 2.2
Values 8.6 12
[161]
liver NOTCH1
Mean 22.8
Standard deviation 16
Values 10 31 8.8 41
[162]
ref_hepatocyte GCK
Mean 0.642
Standard deviation 1.1
Values 0 0 0 0.7 2.5
[163]
HepG2 GCK
Mean 0.00573
Standard deviation 0.0081
Values 0.011 0
[164]
HepG2.C3A GCK
Mean 0.0204
Standard deviation 0.0014
Values 0.019 0.021
[165]
HuH.7 GCK
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[166]
SNU475 GCK
Mean 0.00971
Standard deviation 0.00061
Values 0.0093 0.01
[167]
THLE GCK
Mean 0.042
Standard deviation 0.00081
Values 0.041 0.043
[168]
liver GCK
Mean 3.47
Standard deviation 6.5
Values 13 0.17 0.13 0.38
[169]
ref_hepatocyte MAML3
Mean 0.411
Standard deviation 0.24
Values 0 0.58 0.59 0.46 0.43
[170]
HepG2 MAML3
Mean 0.699
Standard deviation 0.024
Values 0.72 0.68
[171]
HepG2.C3A MAML3
Mean 1.04
Standard deviation 0.079
Values 0.98 1.1
[172]
HuH.7 MAML3
Mean 8.13
Standard deviation 2.1
Values 9.1 9.5 5.8
[173]
SNU475 MAML3
Mean 1.99
Standard deviation 0.56
Values 2.4 1.6
[174]
THLE MAML3
Mean 0.858
Standard deviation 0.2
Values 0.72 1
[175]
liver MAML3
Mean 6.6
Standard deviation 2.8
Values 4.4 9.7 4 8.3
[176]
ref_hepatocyte AKT3
Mean 0.387
Standard deviation 0.32
Values 0 0.53 0.83 0.16 0.41
[177]
HepG2 AKT3
Mean 0.238
Standard deviation 0.15
Values 0.34 0.13
[178]
HepG2.C3A AKT3
Mean 0.036
Standard deviation 0.0097
Values 0.029 0.043
[179]
HuH.7 AKT3
Mean 0.0557
Standard deviation 0.031
Values 0.049 0.09 0.028
[180]
SNU475 AKT3
Mean 40.8
Standard deviation 10
Values 48 34
[181]
THLE AKT3
Mean 22.1
Standard deviation 4.4
Values 25 19
[182]
liver AKT3
Mean 6.71
Standard deviation 4.9
Values 2.8 12 2.3 9.4
[183]
ref_hepatocyte IAPP
Mean 0.301
Standard deviation 0.42
Values 0.52 0.94 0.03 0 0.0081
[184]
HepG2 IAPP
Mean 0.18
Standard deviation 0.012
Values 0.19 0.17
[185]
HepG2.C3A IAPP
Mean 0.263
Standard deviation 0.068
Values 0.31 0.21
[186]
HuH.7 IAPP
Mean 0.285
Standard deviation 0.091
Values 0.26 0.39 0.21
[187]
SNU475 IAPP
Mean 0.147
Standard deviation 0.015
Values 0.16 0.14
[188]
THLE IAPP
Mean 0.174
Standard deviation 0.0028
Values 0.17 0.18
[189]
liver IAPP
Mean 0.155
Standard deviation 0.059
Values 0.21 0.19 0.077 0.15
[190]
ref_hepatocyte MAML2
Mean 0.226
Standard deviation 0.3
Values 0.69 0 0.36 0 0.089
[191]
HepG2 MAML2
Mean 5.61
Standard deviation 0.32
Values 5.8 5.4
[192]
HepG2.C3A MAML2
Mean 7.69
Standard deviation 1.2
Values 8.6 6.8
[193]
HuH.7 MAML2
Mean 0.0778
Standard deviation 0.056
Values 0.13 0.083 0.019
[194]
SNU475 MAML2
Mean 11.4
Standard deviation 0.01
Values 11 11
[195]
THLE MAML2
Mean 5.83
Standard deviation 0.93
Values 5.2 6.5
[196]
liver MAML2
Mean 1.66
Standard deviation 0.64
Values 1.1 1.9 1.2 2.4
[197]
ref_hepatocyte MAFA
Mean 0.0832
Standard deviation 0.19
Values 0 0 0.42 0 0
[198]
HepG2 MAFA
Mean 0.245
Standard deviation 0.16
Values 0.36 0.13
[199]
HepG2.C3A MAFA
Mean 0.0696
Standard deviation 0.053
Values 0.11 0.032
[200]
HuH.7 MAFA
Mean 0.11
Standard deviation 0.033
Values 0.11 0.14 0.075
[201]
SNU475 MAFA
Mean 0.0141
Standard deviation 0.013
Values 0.023 0.0051
[202]
THLE MAFA
Mean 0.0639
Standard deviation 0.015
Values 0.053 0.074
[203]
liver MAFA
Mean 0
Standard deviation 0
Values 0 0 0 0
[204]
ref_hepatocyte PAX6
Mean 0.0716
Standard deviation 0.088
Values 0 0 0.052 0.095 0.21
[205]
HepG2 PAX6
Mean 8.03
Standard deviation 2.9
Values 10 6
[206]
HepG2.C3A PAX6
Mean 2.25
Standard deviation 0.65
Values 2.7 1.8
[207]
HuH.7 PAX6
Mean 6.86
Standard deviation 0.41
Values 7.3 6.8 6.5
[208]
SNU475 PAX6
Mean 3.54
Standard deviation 0.9
Values 2.9 4.2
[209]
THLE PAX6
Mean 0.444
Standard deviation 0.12
Values 0.53 0.36
[210]
liver PAX6
Mean 0.523
Standard deviation 0.14
Values 0.73 0.4 0.46 0.5
[211]
ref_hepatocyte PDX1
Mean 0.0133
Standard deviation 0.02
Values 0.045 0 0.022 0 0
[212]
HepG2 PDX1
Mean 0.0386
Standard deviation 0.006
Values 0.034 0.043
[213]
HepG2.C3A PDX1
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[214]
HuH.7 PDX1
Mean 1.24
Standard deviation 0.28
Values 1.3 0.93 1.5
[215]
SNU475 PDX1
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[216]
THLE PDX1
Mean 0
Standard deviation 0
Values 0 0
[217]
liver PDX1
Mean 0.103
Standard deviation 0.045
Values 0.12 0.057 0.077 0.16
[218]
ref_hepatocyte NKX2-2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[219]
HepG2 NKX2-2
Mean 0
Standard deviation 0
Values 0 0
[220]
HepG2.C3A NKX2-2
Mean 0
Standard deviation 0
Values 0 0
[221]
HuH.7 NKX2-2
Mean 0
Standard deviation 0
Values 0 0 0
[222]
SNU475 NKX2-2
Mean 0.027
Standard deviation 0.012
Values 0.019 0.035
[223]
THLE NKX2-2
Mean 0
Standard deviation 0
Values 0 0
[224]
liver NKX2-2
Mean 0
Standard deviation 0
Values 0 0 0 0
[225]
ref_hepatocyte NEUROG3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[226]
HepG2 NEUROG3
Missing
[227]
HepG2.C3A NEUROG3
Missing
[228]
HuH.7 NEUROG3
Missing
[229]
SNU475 NEUROG3
Missing
[230]
THLE NEUROG3
Missing
[231]
liver NEUROG3
Missing
[232]
ref_hepatocyte RFX6
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[233]
HepG2 RFX6
Mean 0
Standard deviation 0
Values 0 0
[234]
HepG2.C3A RFX6
Mean 0.00972
Standard deviation 0.014
Values 0.019 0
[235]
HuH.7 RFX6
Mean 0.504
Standard deviation 0.4
Values 0.26 0.97 0.28
[236]
SNU475 RFX6
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[237]
THLE RFX6
Mean 0
Standard deviation 0
Values 0 0
[238]
liver RFX6
Mean 0
Standard deviation 0
Values 0 0 0 0
[239]
ref_hepatocyte INS
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[240]
HepG2 INS
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[241]
HepG2.C3A INS
Mean 0
Standard deviation 0
Values 0 0
[242]
HuH.7 INS
Mean 0
Standard deviation 0
Values 0 0 0
[243]
SNU475 INS
Mean 0
Standard deviation 0
Values 0 0
[244]
THLE INS
Mean 0
Standard deviation 0
Values 0 0
[245]
liver INS
Mean 0.0838
Standard deviation 0.13
Values 0 0.057 0 0.28
[246]
ref_hepatocyte PTF1A
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[247]
HepG2 PTF1A
Mean 0
Standard deviation 0
Values 0 0
[248]
HepG2.C3A PTF1A
Mean 0
Standard deviation 0
Values 0 0
[249]
HuH.7 PTF1A
Mean 0
Standard deviation 0
Values 0 0 0
[250]
SNU475 PTF1A
Mean 0
Standard deviation 0
Values 0 0
[251]
THLE PTF1A
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[252]
liver PTF1A
Mean 0
Standard deviation 0
Values 0 0 0 0
[253]
ref_hepatocyte INSM1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[254]
HepG2 INSM1
Mean 0
Standard deviation 0
Values 0 0
[255]
HepG2.C3A INSM1
Mean 0
Standard deviation 0
Values 0 0
[256]
HuH.7 INSM1
Mean 0.0599
Standard deviation 0.029
Values 0.041 0.045 0.094
[257]
SNU475 INSM1
Mean 0
Standard deviation 0
Values 0 0
[258]
THLE INSM1
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[259]
liver INSM1
Mean 0
Standard deviation 0
Values 0 0 0 0
[260]
ref_hepatocyte PAX4
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[261]
HepG2 PAX4
Missing
[262]
HepG2.C3A PAX4
Missing
[263]
HuH.7 PAX4
Missing
[264]
SNU475 PAX4
Missing
[265]
THLE PAX4
Missing
[266]
liver PAX4
Missing
[267]
ref_hepatocyte NKX6-1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[268]
HepG2 NKX6-1
Mean 0.00573
Standard deviation 0.0081
Values 0.011 0
[269]
HepG2.C3A NKX6-1
Mean 0
Standard deviation 0
Values 0 0
[270]
HuH.7 NKX6-1
Mean 0.143
Standard deviation 0.079
Values 0.057 0.21 0.16
[271]
SNU475 NKX6-1
Mean 0.61
Standard deviation 0.29
Values 0.4 0.82
[272]
THLE NKX6-1
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[273]
liver NKX6-1
Mean 0
Standard deviation 0
Values 0 0 0 0
[274]
ref_hepatocyte ONECUT3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[275]
HepG2 ONECUT3
Mean 0.144
Standard deviation 0.11
Values 0.22 0.064
[276]
HepG2.C3A ONECUT3
Mean 0
Standard deviation 0
Values 0 0
[277]
HuH.7 ONECUT3
Mean 0.0238
Standard deviation 0.021
Values 0.033 0.039 0
[278]
SNU475 ONECUT3
Mean 0
Standard deviation 0
Values 0 0
[279]
THLE ONECUT3
Mean 0
Standard deviation 0
Values 0 0
[280]
liver ONECUT3
Mean 0
Standard deviation 0
Values 0 0 0 0
[281]
ref_hepatocyte FGF10
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[282]
HepG2 FGF10
Mean 0
Standard deviation 0
Values 0 0
[283]
HepG2.C3A FGF10
Mean 0
Standard deviation 0
Values 0 0
[284]
HuH.7 FGF10
Mean 0
Standard deviation 0
Values 0 0 0
[285]
SNU475 FGF10
Mean 0
Standard deviation 0
Values 0 0
[286]
THLE FGF10
Mean 0
Standard deviation 0
Values 0 0
[287]
liver FGF10
Mean 0.0234
Standard deviation 0.038
Values 0 0.014 0 0.079
[288]
ref_hepatocyte NEUROD1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[289]
HepG2 NEUROD1
Mean 0
Standard deviation 0
Values 0 0
[290]
HepG2.C3A NEUROD1
Mean 0
Standard deviation 0
Values 0 0
[291]
HuH.7 NEUROD1
Mean 0.00312
Standard deviation 0.0054
Values 0 0 0.0094
[292]
SNU475 NEUROD1
Mean 0
Standard deviation 0
Values 0 0
[293]
THLE NEUROD1
Mean 0
Standard deviation 0
Values 0 0
[294]
liver NEUROD1
Mean 0.185
Standard deviation 0.02
Values 0.16 0.2 0.21 0.17