REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | HSP90AA1 | Heat shock protein HSP 90-alpha | [1] | -0.81[2] | 0.07[3] | -0.63[4] | -0.23[5] | -0.35[6] | -0.60[7] |
2 | YWHAE | 14-3-3 protein epsilon | [8] | -1.40[9] | -1.38[10] | -0.97[11] | -1.18[12] | -0.94[13] | -0.90[14] |
3 | TUBB4B | Tubulin beta-4B chain | [15] | -0.95[16] | -1.14[17] | -1.10[18] | -1.96[19] | -0.87[20] | -0.80[21] |
4 | TUBB | Tubulin beta chain | [22] | 1.62[23] | 0.80[24] | 1.25[25] | 1.25[26] | 0.76[27] | -0.11[28] |
5 | DYNLL1 | Dynein light chain 1, cytoplasmic | [29] | -1.55[30] | -1.60[31] | -1.75[32] | -1.94[33] | -2.02[34] | -1.45[35] |
6 | TUBA4A | Tubulin alpha-4A chain | [36] | -4.21[37] | -4.47[38] | -5.18[39] | -2.12[40] | -2.09[41] | -1.96[42] |
7 | CETN2 | Centrin-2 | [43] | -2.77[44] | -2.48[45] | -3.59[46] | -2.98[47] | -3.20[48] | -2.83[49] |
8 | YWHAG | 14-3-3 protein gamma | [50] | 0.04[51] | -0.59[52] | -0.47[53] | 0.40[54] | -0.09[55] | -0.69[56] |
9 | MZT2B | Mitotic-spindle organizing protein 2B | [57] | -2.53[58] | -1.76[59] | -2.86[60] | -3.63[61] | -2.78[62] | -1.83[63] |
10 | DCTN2 | Dynactin subunit 2 | [64] | -0.55[65] | -0.17[66] | -0.34[67] | -0.47[68] | -0.44[69] | -0.79[70] |
11 | PPP2R1A | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isofor | 0.64[71] | 0.37[72] | 0.36[73] | 0.89[74] | 0.41[75] | 0.80[76] | |
12 | SSNA1 | Sjoegren syndrome nuclear autoantigen 1 | [77] | -1.61[78] | -1.76[79] | -1.69[80] | -1.97[81] | -1.84[82] | -1.27[83] |
13 | MZT2A | Mitotic-spindle organizing protein 2A | [84] | -1.53[85] | -1.06[86] | -2.30[87] | -3.46[88] | -3.52[89] | -1.99[90] |
14 | MAPRE1 | Microtubule-associated protein RP/EB family member 1 | [91] | 1.51[92] | 1.01[93] | 0.42[94] | 1.37[95] | 0.79[96] | -0.89[97] |
15 | HAUS4 | HAUS augmin-like complex subunit 4 | [98] | -0.41[99] | -1.74[100] | 0.49[101] | -2.28[102] | -1.66[103] | -2.74[104] |
16 | DCTN3 | Dynactin subunit 3 | [105] | -2.12[106] | -2.01[107] | -1.80[108] | -2.37[109] | -1.09[110] | -0.90[111] |
17 | CSNK1D | Casein kinase I isoform delta | [112] | 1.01[113] | 0.69[114] | 0.66[115] | 0.70[116] | 0.44[117] | 0.06[118] |
18 | TUBG1 | Tubulin gamma-1 chain | [119] | 0.08[120] | 0.88[121] | -0.09[122] | -0.80[123] | -0.56[124] | -0.80[125] |
19 | DYNC1I2 | Cytoplasmic dynein 1 intermediate chain 2 | [126] | 0.26[127] | 0.63[128] | 0.49[129] | 0.48[130] | 0.33[131] | 0.08[132] |
20 | PRKACA | cAMP-dependent protein kinase catalytic subunit alpha | [133] | -0.33[134] | -0.59[135] | -0.53[136] | -0.79[137] | 0.00[138] | -0.12[139] |
21 | ACTR1A | Alpha-centractin | [140] | 0.81[141] | 0.88[142] | 1.08[143] | 0.18[144] | 1.18[145] | 1.03[146] |
22 | DCTN1 | Dynactin subunit 1 | [147] | 1.70[148] | 0.77[149] | 0.18[150] | 1.11[151] | 1.31[152] | 1.21[153] |
23 | CDK11B | Cyclin-dependent kinase 11B | [154] | -2.13[155] | -1.95[156] | -1.86[157] | -1.98[158] | -1.76[159] | -2.46[160] |
24 | PAFAH1B1 | Platelet-activating factor acetylhydrolase IB subunit alpha | [161] | 0.62[162] | 0.65[163] | 0.66[164] | 1.82[165] | 1.88[166] | 1.50[167] |
25 | DYNC1H1 | Cytoplasmic dynein 1 heavy chain 1 | [168] | 3.40[169] | 1.91[170] | 2.78[171] | 3.34[172] | 3.55[173] | 3.85[174] |
26 | CDK11A | Cyclin-dependent kinase 11A | [175] | -2.27[176] | -1.45[177] | -1.84[178] | -2.31[179] | -2.00[180] | -1.76[181] |
27 | CEP57 | Centrosomal protein of 57 kDa | [182] | -0.31[183] | 1.25[184] | 1.68[185] | 0.24[186] | 0.14[187] | 1.66[188] |
28 | TUBGCP2 | Gamma-tubulin complex component 2 | [189] | 1.15[190] | 1.27[191] | 1.56[192] | 0.21[193] | 1.12[194] | 1.60[195] |
29 | CSNK1E | Casein kinase I isoform epsilon | [196] | 1.20[197] | 0.75[198] | 1.46[199] | 0.15[200] | 1.41[201] | -0.17[202] |
30 | NME7 | Nucleoside diphosphate kinase 7 | [203] | -1.87[204] | -1.69[205] | -1.43[206] | -0.79[207] | -1.03[208] | -0.78[209] |
31 | HAUS1 | HAUS augmin-like complex subunit 1 | [210] | -0.67[211] | 0.34[212] | -0.11[213] | -0.41[214] | 0.16[215] | -1.23[216] |
32 | CDK5RAP2 | CDK5 regulatory subunit-associated protein 2 | [217] | 1.21[218] | 1.37[219] | 1.41[220] | 1.57[221] | 1.33[222] | 1.59[223] |
33 | CDK1 | Cyclin-dependent kinase 1 | [224] | 1.09[225] | 3.06[226] | 1.86[227] | 1.95[228] | 2.97[229] | -1.81[230] |
34 | CEP63 | Centrosomal protein of 63 kDa | [231] | -1.94[232] | -0.50[233] | -0.50[234] | -1.60[235] | -1.05[236] | 0.21[237] |
35 | CKAP5 | Cytoskeleton-associated protein 5 | [238] | 2.30[239] | 2.37[240] | 3.14[241] | 2.16[242] | 2.68[243] | 2.15[244] |
36 | ODF2 | Outer dense fiber protein 2 | [245] | 0.54[246] | 0.84[247] | 1.39[248] | 0.51[249] | 1.02[250] | 1.08[251] |
37 | PCM1 | Pericentriolar material 1 protein | [252] | 0.71[253] | 2.56[254] | 2.63[255] | 1.12[256] | 1.40[257] | 3.82[258] |
38 | PLK1 | Serine/threonine-protein kinase PLK1 | [259] | 2.33[260] | 1.98[261] | 1.90[262] | 0.93[263] | 2.16[264] | -1.97[265] |
39 | CEP70 | Centrosomal protein of 70 kDa | [266] | -2.07[267] | -0.25[268] | 0.34[269] | -0.84[270] | -0.48[271] | 1.19[272] |
40 | TUBA1A | Tubulin alpha-1A chain | [273] | 2.00[274] | -1.46[275] | -4.60[276] | 3.76[277] | 1.49[278] | 0.66[279] |
41 | HAUS2 | HAUS augmin-like complex subunit 2 | [280] | 0.87[281] | 0.87[282] | 0.88[283] | 1.49[284] | 1.61[285] | 0.28[286] |
42 | TUBGCP3 | Gamma-tubulin complex component 3 | [287] | 0.59[288] | 0.47[289] | 1.02[290] | 0.49[291] | 1.02[292] | 2.05[293] |
43 | TUBGCP5 | Gamma-tubulin complex component 5 | [294] | -0.11[295] | 0.33[296] | -0.13[297] | 0.12[298] | 1.22[299] | 1.82[300] |
44 | MZT1 | Mitotic-spindle organizing protein 1 | [301] | 0.75[302] | 1.84[303] | 2.10[304] | 0.65[305] | 1.47[306] | -0.45[307] |
45 | NINL | Ninein-like protein | [308] | 1.89[309] | 2.25[310] | 1.81[311] | 0.66[312] | -0.52[313] | 0.61[314] |
46 | HAUS8 | HAUS augmin-like complex subunit 8 | [315] | -0.29[316] | -0.12[317] | 0.91[318] | -0.42[319] | 0.29[320] | -0.60[321] |
47 | HAUS7 | HAUS augmin-like complex subunit 7 | [322] | 0.22[323] | 0.04[324] | 0.05[325] | -0.55[326] | -0.18[327] | 0.59[328] |
48 | CLASP1 | CLIP-associating protein 1 | [329] | 2.38[330] | 2.28[331] | 2.03[332] | 2.20[333] | 2.45[334] | 3.57[335] |
49 | HAUS6 | HAUS augmin-like complex subunit 6 | [336] | 1.15[337] | 2.33[338] | 2.16[339] | 1.49[340] | 2.40[341] | 1.70[342] |
50 | SDCCAG8 | Serologically defined colon cancer antigen 8 | [343] | -0.90[344] | -0.15[345] | 0.06[346] | 0.10[347] | -0.52[348] | 1.75[349] |
51 | TUBG2 | Tubulin gamma-2 chain | [350] | -0.20[351] | 0.90[352] | -0.62[353] | 0.24[354] | -0.39[355] | 0.36[356] |
52 | OFD1 | Oral-facial-digital syndrome 1 protein | [357] | -0.63[358] | 1.03[359] | 1.01[360] | 0.48[361] | 0.39[362] | 1.96[363] |
53 | NEDD1 | Protein NEDD1 | [364] | 0.25[365] | 1.49[366] | 1.08[367] | 1.95[368] | 2.18[369] | 1.27[370] |
54 | AKAP9 | A-kinase anchor protein 9 | [371] | -0.14[372] | 2.48[373] | 2.73[374] | 1.48[375] | 1.79[376] | 5.73[377] |
55 | NEK2 | Serine/threonine-protein kinase Nek2 | [378] | 0.86[379] | 1.83[380] | 2.51[381] | 1.82[382] | 2.48[383] | -1.62[384] |
56 | CEP250 | Centrosome-associated protein CEP250 | [385] | 3.32[386] | 2.87[387] | 2.92[388] | 2.98[389] | 2.52[390] | 2.01[391] |
57 | TUBGCP6 | Gamma-tubulin complex component 6 | [392] | 1.32[393] | 2.52[394] | 3.23[395] | 1.14[396] | 1.44[397] | 3.57[398] |
58 | TUBGCP4 | Gamma-tubulin complex component 4 | [399] | 1.37[400] | 1.23[401] | 1.34[402] | 0.72[403] | 1.60[404] | 2.41[405] |
59 | NDE1 | Nuclear distribution protein nudE homolog 1 | [406] | 2.50[407] | 1.68[408] | 0.74[409] | 0.44[410] | 1.61[411] | 0.60[412] |
60 | CEP164 | Centrosomal protein of 164 kDa | [413] | 1.96[414] | 1.92[415] | 1.75[416] | 2.12[417] | 1.99[418] | 2.01[419] |
61 | CCP110 | Centriolar coiled-coil protein of 110 kDa | [420] | 0.80[421] | 1.55[422] | 0.44[423] | 0.63[424] | 1.85[425] | 2.00[426] |
62 | CEP78 | Centrosomal protein of 78 kDa | [427] | 0.47[428] | 1.27[429] | 1.95[430] | 1.06[431] | 2.11[432] | 1.53[433] |
63 | HAUS3 | HAUS augmin-like complex subunit 3 | [434] | 0.26[435] | 1.33[436] | 1.81[437] | 1.81[438] | 1.88[439] | 1.98[440] |
64 | HAUS5 | HAUS augmin-like complex subunit 5 | [441] | 1.33[442] | 1.93[443] | 3.28[444] | 1.33[445] | 2.03[446] | 1.26[447] |
65 | CEP76 | Centrosomal protein of 76 kDa | [448] | 0.99[449] | 1.92[450] | 2.55[451] | 1.33[452] | 1.32[453] | 1.39[454] |
66 | SFI1 | Protein SFI1 homolog | [455] | 1.60[456] | 3.40[457] | 2.27[458] | 0.88[459] | 1.23[460] | 1.83[461] |
67 | PCNT | Pericentrin | [462] | 2.52[463] | 2.87[464] | 2.36[465] | 3.14[466] | 3.16[467] | 4.50[468] |
68 | CEP290 | Centrosomal protein of 290 kDa | [469] | 0.10[470] | 3.08[471] | 2.06[472] | 1.83[473] | 1.98[474] | 2.51[475] |
69 | CENPJ | Centromere protein J | [476] | 0.31[477] | 2.00[478] | 2.22[479] | 2.50[480] | 2.04[481] | 1.46[482] |
70 | CEP192 | Centrosomal protein of 192 kDa | [483] | 2.06[484] | 3.43[485] | 4.60[486] | 3.44[487] | 3.45[488] | 4.37[489] |
71 | PLK4 | Serine/threonine-protein kinase PLK4 | [490] | 1.67[491] | 3.21[492] | 2.35[493] | 2.26[494] | 3.33[495] | -0.48[496] |
72 | CNTRL | Centriolin | [497] | 0.84[498] | 3.00[499] | 3.90[500] | 2.44[501] | 2.34[502] | 3.24[503] |
73 | CEP72 | Centrosomal protein of 72 kDa | [504] | 1.02[505] | 0.91[506] | 2.01[507] | 0.54[508] | 1.23[509] | 1.75[510] |
74 | CEP135 | Centrosomal protein of 135 kDa | [511] | 0.29[512] | 1.50[513] | 1.21[514] | 1.77[515] | 1.93[516] | 2.00[517] |
75 | CEP41 | Centrosomal protein of 41 kDa | [518] | 1.96[519] | 1.71[520] | 2.58[521] | 2.92[522] | 2.91[523] | 2.41[524] |
76 | ALMS1 | Alstrom syndrome protein 1 | [525] | 2.49[526] | 3.97[527] | 3.88[528] | 3.67[529] | 3.70[530] | 5.30[531] |
77 | CEP152 | Centrosomal protein of 152 kDa | [532] | 1.48[533] | 3.38[534] | 3.61[535] | 3.53[536] | 3.78[537] | 3.57[538] |
78 | PRKAR2B | cAMP-dependent protein kinase type II-beta regulatory subunit | [539] | -2.50[540] | -0.77[541] | 3.58[542] | 4.77[543] | 3.48[544] | 3.97[545] |
79 | TUBB4A | Tubulin beta-4A chain | [546] | 1.66[547] | -2.55[548] | 4.04[549] | 3.31[550] | 2.08[551] | 2.50[552] |
80 | CEP43 | [553] | [554] | [555] | [556] | [557] | [558] | [559] | |
81 | CEP131 | Centrosomal protein of 131 kDa | [560] | [561] | [562] | [563] | [564] | [565] | [566] |