REACTOME_RECOGNITION_OF_DNA_DAMAGE_BY_PCNA_CONTAINING_REPLICATION_CO | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | UBB | Polyubiquitin-B | [1] | -0.73[2] | -1.00[3] | -1.16[4] | -1.16[5] | -0.91[6] | -0.20[7] |
2 | RPS27A | Ubiquitin-40S ribosomal protein S27a | [8] | [9] | [10] | [11] | [12] | [13] | [14] |
3 | UBC | Polyubiquitin-C | [15] | -0.29[16] | -0.25[17] | -0.79[18] | -0.31[19] | -0.53[20] | 0.25[21] |
4 | UBA52 | Ubiquitin-60S ribosomal protein L40 | [22] | 2.15[23] | 1.99[24] | 2.72[25] | 1.09[26] | 1.69[27] | 1.02[28] |
5 | RBX1 | E3 ubiquitin-protein ligase RBX1 | [29] | -0.59[30] | -0.23[31] | -0.65[32] | -1.09[33] | -0.87[34] | -0.43[35] |
6 | PCNA | Proliferating cell nuclear antigen | [36] | 2.35[37] | 2.27[38] | 0.55[39] | 1.40[40] | 1.47[41] | -1.40[42] |
7 | POLD2 | DNA polymerase delta subunit 2 | [43] | 0.86[44] | 0.97[45] | 1.17[46] | 0.75[47] | 0.91[48] | 1.55[49] |
8 | POLD4 | DNA polymerase delta subunit 4 | [50] | -0.67[51] | -1.08[52] | 0.69[53] | 3.06[54] | -0.74[55] | 1.20[56] |
9 | DDB1 | DNA damage-binding protein 1 | [57] | 3.08[58] | 2.37[59] | 3.20[60] | 2.46[61] | 2.28[62] | 2.27[63] |
10 | POLE3 | DNA polymerase epsilon subunit 3 | [64] | 0.68[65] | 0.47[66] | 0.46[67] | 0.56[68] | 1.39[69] | 0.10[70] |
11 | POLE4 | DNA polymerase epsilon subunit 4 | [71] | 0.42[72] | 1.09[73] | -2.67[74] | -0.01[75] | -0.69[76] | -0.13[77] |
12 | RPA2 | Replication protein A 32 kDa subunit | [78] | 0.01[79] | 0.01[80] | 0.27[81] | 0.87[82] | 0.74[83] | -0.73[84] |
13 | UBE2B | Ubiquitin-conjugating enzyme E2 B | [85] | 0.99[86] | 1.36[87] | 0.30[88] | 1.02[89] | 1.12[90] | 0.96[91] |
14 | CUL4A | Cullin-4A | [92] | 1.70[93] | 1.92[94] | 0.91[95] | 1.55[96] | 1.15[97] | 2.25[98] |
15 | RFC4 | Replication factor C subunit 4 | [99] | 0.49[100] | 1.06[101] | 1.33[102] | 0.65[103] | 1.77[104] | -1.08[105] |
16 | RFC1 | Replication factor C subunit 1 | [106] | 1.61[107] | 2.83[108] | 2.90[109] | 1.94[110] | 2.57[111] | 2.45[112] |
17 | RFC2 | Replication factor C subunit 2 | [113] | 1.20[114] | 0.99[115] | 0.73[116] | 1.79[117] | 2.05[118] | 0.90[119] |
18 | RPA1 | Replication protein A 70 kDa DNA-binding subunit | [120] | 2.78[121] | 2.45[122] | 2.41[123] | 3.47[124] | 3.28[125] | 1.68[126] |
19 | RPA3 | Replication protein A 14 kDa subunit | [127] | 1.10[128] | 1.83[129] | 2.25[130] | 0.71[131] | 0.79[132] | 0.98[133] |
20 | CUL4B | Cullin-4B | [134] | 1.37[135] | 2.69[136] | 3.86[137] | 3.93[138] | 4.66[139] | 2.55[140] |
21 | RFC5 | Replication factor C subunit 5 | [141] | 1.59[142] | 1.99[143] | 1.88[144] | 1.88[145] | 2.20[146] | 0.80[147] |
22 | USP1 | Ubiquitin carboxyl-terminal hydrolase 1 | [148] | 2.00[149] | 3.33[150] | 3.14[151] | 3.39[152] | 3.54[153] | 2.00[154] |
23 | WDR48 | WD repeat-containing protein 48 | [155] | 2.51[156] | 3.31[157] | 3.19[158] | 2.11[159] | 2.49[160] | 2.89[161] |
24 | RFC3 | Replication factor C subunit 3 | [162] | 2.64[163] | 3.44[164] | 3.27[165] | 2.87[166] | 3.26[167] | 0.80[168] |
25 | POLD1 | DNA polymerase delta catalytic subunit | [169] | 3.32[170] | 3.48[171] | 3.99[172] | 3.44[173] | 3.99[174] | 2.34[175] |
26 | POLD3 | DNA polymerase delta subunit 3 | [176] | 2.64[177] | 2.44[178] | 3.11[179] | 3.73[180] | 4.01[181] | 2.66[182] |
27 | POLE | DNA polymerase epsilon catalytic subunit A | [183] | 4.51[184] | 5.07[185] | 4.81[186] | 4.35[187] | 5.16[188] | 4.61[189] |
28 | DTL | Denticleless protein homolog | [190] | 3.70[191] | 3.42[192] | 4.03[193] | 4.76[194] | 4.45[195] | 0.38[196] |
29 | POLE2 | DNA polymerase epsilon subunit 2 | [197] | 2.17[198] | 2.90[199] | 3.58[200] | 2.77[201] | 3.10[202] | 0.52[203] |
30 | RAD18 | E3 ubiquitin-protein ligase RAD18 | [204] | 2.61[205] | 3.74[206] | 4.62[207] | 3.98[208] | 4.34[209] | 2.68[210] |