REACTOME_AQUAPORIN_MEDIATED_TRANSPORT | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | GNAS | Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas | 0.62[1] | 0.64[2] | 0.32[3] | 0.73[4] | 0.16[5] | -1.11[6] | |
2 | GNG5 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 | -1.02[7] | -0.85[8] | -1.69[9] | -1.93[10] | -2.00[11] | -1.36[12] | |
3 | AQP9 | Aquaporin-9 | [13] | -12.37[14] | -12.21[15] | -13.84[16] | -10.63[17] | -11.15[18] | 0.17[19] |
4 | PRKAR1A | cAMP-dependent protein kinase type I-alpha regulatory subunit | [20] | 0.26[21] | 0.38[22] | 0.55[23] | -0.21[24] | -0.12[25] | 0.82[26] |
5 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | [27] | 1.20[28] | 1.21[29] | 0.76[30] | 1.17[31] | 1.15[32] | -1.01[33] |
6 | GNB2 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 | [34] | -0.41[35] | -0.67[36] | -0.31[37] | -0.48[38] | -0.23[39] | -1.37[40] |
7 | AQP3 | Aquaporin-3 | [41] | -2.49[42] | -5.83[43] | -4.85[44] | -6.37[45] | -7.05[46] | -0.02[47] |
8 | GNG10 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 | -4.51[48] | -4.23[49] | -4.51[50] | -3.93[51] | -2.92[52] | -4.12[53] | |
9 | GNG12 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 | -4.56[54] | -7.50[55] | 0.47[56] | 1.76[57] | 2.05[58] | 0.71[59] | |
10 | PRKACA | cAMP-dependent protein kinase catalytic subunit alpha | [60] | 0.02[61] | -0.16[62] | -0.13[63] | -0.59[64] | 0.20[65] | -0.55[66] |
11 | RAB11A | Ras-related protein Rab-11A | [67] | 0.88[68] | 1.24[69] | 1.86[70] | 0.87[71] | 1.08[72] | 0.60[73] |
12 | PRKAR2A | cAMP-dependent protein kinase type II-alpha regulatory subunit | [74] | 0.24[75] | -0.08[76] | 1.05[77] | -0.40[78] | -0.35[79] | 0.37[80] |
13 | PRKAR1B | cAMP-dependent protein kinase type I-beta regulatory subunit | [81] | 1.16[82] | 0.60[83] | -1.16[84] | -4.22[85] | -1.23[86] | 0.06[87] |
14 | AQP7 | Aquaporin-7 | [88] | -4.11[89] | -3.00[90] | -3.61[91] | -8.80[92] | -10.99[93] | -0.70[94] |
15 | MYO5B | Unconventional myosin-Vb | [95] | 1.35[96] | 1.88[97] | -0.64[98] | 0.03[99] | -1.98[100] | 2.07[101] |
16 | GNB5 | Guanine nucleotide-binding protein subunit beta-5 | [102] | 0.29[103] | 0.32[104] | 1.36[105] | 0.67[106] | 0.98[107] | 1.12[108] |
17 | AQP11 | Aquaporin-11 | [109] | 0.33[110] | 0.00[111] | -1.25[112] | -1.85[113] | -3.51[114] | 0.84[115] |
18 | PRKACB | cAMP-dependent protein kinase catalytic subunit beta | [116] | -0.64[117] | 0.12[118] | 1.43[119] | 2.11[120] | 1.17[121] | 1.94[122] |
19 | ADCY9 | Adenylate cyclase type 9 | [123] | 2.81[124] | 1.99[125] | 2.44[126] | 0.84[127] | 0.58[128] | 2.64[129] |
20 | ADCY6 | Adenylate cyclase type 6 | [130] | 2.24[131] | 2.69[132] | 2.68[133] | 2.39[134] | 3.25[135] | 2.86[136] |
21 | GNG11 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 | -7.99[137] | -8.00[138] | -7.28[139] | 2.15[140] | 3.66[141] | 2.46[142] | |
22 | RAB11FIP | Rab11 family-interacting protein 2 | [143] | 0.70[144] | 2.00[145] | 1.29[146] | 1.29[147] | 1.86[148] | 2.28[149] |
23 | GNG7 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 | 1.74[150] | 1.39[151] | 2.22[152] | -2.35[153] | -1.54[154] | 0.25[155] | |
24 | ADCY1 | Adenylate cyclase type 1 | [156] | -0.65[157] | -2.53[158] | -2.70[159] | -2.23[160] | -2.05[161] | 5.22[162] |
25 | GNG4 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 | 3.66[163] | 1.41[164] | 5.24[165] | 1.14[166] | -0.78[167] | -2.32[168] | |
26 | ADCY7 | Adenylate cyclase type 7 | [169] | 3.70[170] | 3.31[171] | 2.30[172] | 3.19[173] | 2.86[174] | 3.15[175] |
27 | GNB4 | Guanine nucleotide-binding protein subunit beta-4 | [176] | -0.18[177] | 0.30[178] | 1.33[179] | 2.56[180] | 5.49[181] | 4.32[182] |
28 | GNG2 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | -6.09[183] | -6.98[184] | [185] | 3.00[186] | 2.67[187] | 3.01[188] | |
29 | AQP1 | Aquaporin-1 | [189] | -4.56[190] | [191] | -1.62[192] | 2.48[193] | -1.75[194] | 4.63[195] |
30 | AQP6 | Aquaporin-6 | [196] | -1.23[197] | 0.02[198] | -0.99[199] | -1.30[200] | -2.05[201] | -1.41[202] |
31 | AVP | Vasopressin-neurophysin 2-copeptin | [203] | -3.87[204] | -1.44[205] | -1.83[206] | [207] | -7.48[208] | -0.84[209] |
32 | GNGT2 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 | [210] | [211] | [212] | -2.19[213] | -6.66[214] | 0.34[215] | |
33 | MIP | Lens fiber major intrinsic protein | [216] | -2.42[217] | -1.19[218] | -3.83[219] | -4.22[220] | [221] | 0.82[222] |
34 | GNG3 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 | -0.67[223] | 1.16[224] | -1.05[225] | -0.82[226] | -0.94[227] | 0.14[228] | |
35 | PRKAR2B | cAMP-dependent protein kinase type II-beta regulatory subunit | [229] | -2.15[230] | -0.33[231] | 3.97[232] | 4.97[233] | 3.67[234] | 3.54[235] |
36 | ADCY3 | Adenylate cyclase type 3 | [236] | 1.65[237] | 0.40[238] | 3.75[239] | 4.62[240] | 6.34[241] | 3.74[242] |
37 | ADCY2 | Adenylate cyclase type 2 | [243] | -5.19[244] | -3.27[245] | -4.50[246] | -2.85[247] | -3.78[248] | -3.89[249] |
38 | AQP4 | Aquaporin-4 | [250] | -0.04[251] | 1.57[252] | 4.20[253] | -4.10[254] | -5.50[255] | 1.56[256] |
39 | GNB3 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 | [257] | 1.78[258] | 4.02[259] | 3.35[260] | 0.89[261] | 3.80[262] | -1.45[263] |
40 | AQP8 | Aquaporin-8 | [264] | 3.60[265] | 4.47[266] | -0.95[267] | [268] | [269] | -1.94[270] |
41 | ADCY5 | Adenylate cyclase type 5 | [271] | 0.34[272] | 1.33[273] | 2.39[274] | 0.53[275] | 1.85[276] | 6.60[277] |
42 | AQP10 | Aquaporin-10 | [278] | 1.91[279] | 2.94[280] | 4.62[281] | -4.50[282] | -1.18[283] | -2.16[284] |
43 | AVPR2 | Vasopressin V2 receptor | [285] | 0.21[286] | 0.58[287] | -3.72[288] | 0.26[289] | -2.51[290] | 2.37[291] |
44 | ADCY4 | Adenylate cyclase type 4 | [292] | 0.28[293] | -0.80[294] | 1.87[295] | [296] | [297] | 8.60[298] |
45 | AQP12A | Aquaporin-12A | [299] | [300] | [301] | [302] | [303] | [304] | [305] |
46 | AQP2 | Aquaporin-2 | [306] | [307] | [308] | [309] | [310] | [311] | [312] |
47 | PRKACG | cAMP-dependent protein kinase catalytic subunit gamma | [313] | [314] | [315] | [316] | [317] | [318] | [319] |
48 | GNGT1 | Guanine nucleotide-binding protein G(T) subunit gamma-T1 | [320] | [321] | [322] | [323] | [324] | [325] | [326] |
49 | ADCY8 | Adenylate cyclase type 8 | [327] | [328] | [329] | [330] | [331] | [332] | [333] |
50 | GNG13 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 | [334] | [335] | [336] | [337] | [338] | [339] | |
51 | AQP5 | Aquaporin-5 | [340] | [341] | [342] | [343] | [344] | [345] | [346] |
52 | GNG8 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 | [347] | [348] | [349] | [350] | [351] | [352] |