REACTOME_RAS_PROCESSING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 UBB Polyubiquitin-B [1] -0.67[2] -0.82[3] -1.04[4] -0.83[5] -0.50[6] -0.25[7]
2 RPS27A Ubiquitin-40S ribosomal protein S27a [8] [9] [10] [11] [12] [13] [14]
3 UBC Polyubiquitin-C [15] -0.22[16] -0.07[17] -0.68[18] 0.02[19] -0.12[20] 0.20[21]
4 UBA52 Ubiquitin-60S ribosomal protein L40 [22] 2.21[23] 2.16[24] 2.83[25] 1.42[26] 2.10[27] 0.97[28]
5 CALM1 Calmodulin-1 [29] 1.61[30] 1.69[31] 1.78[32] 3.53[33] 2.68[34] 3.25[35]
6 BCL2L1 Bcl-2-like protein 1 [36] 3.67[37] 3.10[38] 3.69[39] 1.33[40] 1.59[41] 0.81[42]
7 GOLGA7 Golgin subfamily A member 7 [43] 0.06[44] 0.69[45] 1.05[46] 0.40[47] 0.58[48] 0.90[49]
8 FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 0.64[50] 1.64[51] 1.82[52] 0.33[53] 0.72[54] 0.73[55]
9 LYPLA1 Acyl-protein thioesterase 1 [56] 1.62[57] 2.33[58] 1.02[59] 2.10[60] 1.82[61] 2.15[62]
10 NRAS GTPase NRas [63] 2.16[64] 2.64[65] 2.68[66] 2.95[67] 2.39[68] 1.38[69]
11 HRAS GTPase HRas [70] 0.53[71] -0.14[72] -1.30[73] 1.00[74] 0.66[75] -1.03[76]
12 ZDHHC9 Palmitoyltransferase ZDHHC9 [77] 2.74[78] 2.63[79] 2.71[80] 1.69[81] 1.66[82] 2.54[83]
13 KRAS GTPase KRas [84] 1.02[85] 1.04[86] 2.27[87] 2.75[88] 2.28[89] 2.30[90]
14 ARL2 ADP-ribosylation factor-like protein 2 [91] 1.26[92] 1.65[93] -1.22[94] 1.38[95] 1.43[96] -0.59[97]
15 ICMT Protein-S-isoprenylcysteine O-methyltransferase [98] 3.49[99] 3.90[100] 3.05[101] 3.73[102] 4.33[103] 2.53[104]
16 PDE6D Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta 0.40[105] -0.38[106] 0.83[107] 1.19[108] 1.38[109] 0.13[110]
17 RCE1 CAAX prenyl protease 2 [111] 2.36[112] 2.24[113] 3.62[114] 2.65[115] 1.92[116] 0.26[117]
18 FNTB Protein farnesyltransferase subunit beta [118] 0.45[119] 0.23[120] -2.41[121] 0.14[122] -0.66[123] -0.66[124]
19 PRKCQ Protein kinase C theta type [125] 2.44[126] -1.08[127] [128] 4.08[129] 5.45[130] 3.72[131]
20 PRKG2 cGMP-dependent protein kinase 2 [132] 4.44[133] [134] [135] 8.74[136] 2.90[137] 3.67[138]
21 ABHD17C Protein ABHD17C [139] [140] [141] [142] [143] [144] [145]
22 USP17L2 Ubiquitin carboxyl-terminal hydrolase 17 [146] [147] [148] [149] [150] [151] [152]
23 ABHD17B Protein ABHD17B [153] [154] [155] [156] [157] [158] [159]
24 ABHD17A Protein ABHD17A [160] [161] [162] [163] [164] [165] [166]
[1]
ref_hepatocyte UBB
Mean 764
Standard deviation 4.8e+02
Values 3.8e+02 3.5e+02 5.3e+02 1.2e+03 1.3e+03
[2]
HepG2 UBB
Mean 368
Standard deviation 39
Values 4e+02 3.4e+02
[3]
HepG2.C3A UBB
Mean 285
Standard deviation 14
Values 2.8e+02 3e+02
[4]
HuH.7 UBB
Mean 304
Standard deviation 40
Values 2.9e+02 2.7e+02 3.5e+02
[5]
SNU475 UBB
Mean 204
Standard deviation 3.3
Values 2.1e+02 2e+02
[6]
THLE UBB
Mean 315
Standard deviation 34
Values 2.9e+02 3.4e+02
[7]
liver UBB
Mean 296
Standard deviation 1.3e+02
Values 4.3e+02 2.1e+02 3.9e+02 1.5e+02
[8]
ref_hepatocyte RPS27A
Mean 499
Standard deviation 2.2e+02
Values 6.6e+02 6.1e+02 1.7e+02 6.8e+02 3.8e+02
[9]
HepG2 RPS27A
Missing
[10]
HepG2.C3A RPS27A
Missing
[11]
HuH.7 RPS27A
Missing
[12]
SNU475 RPS27A
Missing
[13]
THLE RPS27A
Missing
[14]
liver RPS27A
Missing
[15]
ref_hepatocyte UBC
Mean 480
Standard deviation 2.8e+02
Values 1.8e+02 3.5e+02 9.1e+02 5.8e+02 3.8e+02
[16]
HepG2 UBC
Mean 314
Standard deviation 38
Values 3.4e+02 2.9e+02
[17]
HepG2.C3A UBC
Mean 302
Standard deviation 41
Values 3.3e+02 2.7e+02
[18]
HuH.7 UBC
Mean 246
Standard deviation 64
Values 2.4e+02 3.1e+02 1.9e+02
[19]
SNU475 UBC
Mean 232
Standard deviation 63
Values 2.8e+02 1.9e+02
[20]
THLE UBC
Mean 257
Standard deviation 41
Values 2.3e+02 2.9e+02
[21]
liver UBC
Mean 254
Standard deviation 78
Values 2.2e+02 3.1e+02 3.3e+02 1.6e+02
[22]
ref_hepatocyte UBA52
Mean 57.3
Standard deviation 43
Values 14 23 49 1.2e+02 81
[23]
HepG2 UBA52
Mean 203
Standard deviation 20
Values 2.2e+02 1.9e+02
[24]
HepG2.C3A UBA52
Mean 169
Standard deviation 3.3
Values 1.7e+02 1.7e+02
[25]
HuH.7 UBA52
Mean 334
Standard deviation 46
Values 3.4e+02 2.8e+02 3.7e+02
[26]
SNU475 UBA52
Mean 72.9
Standard deviation 11
Values 65 81
[27]
THLE UBA52
Mean 144
Standard deviation 15
Values 1.3e+02 1.5e+02
[28]
liver UBA52
Mean 51.7
Standard deviation 26
Values 79 32 68 28
[29]
ref_hepatocyte CALM1
Mean 29.2
Standard deviation 11
Values 17 40 21 28 40
[30]
HepG2 CALM1
Mean 67.9
Standard deviation 4.3
Values 65 71
[31]
HepG2.C3A CALM1
Mean 62
Standard deviation 16
Values 51 73
[32]
HuH.7 CALM1
Mean 81.9
Standard deviation 15
Values 90 64 92
[33]
SNU475 CALM1
Mean 160
Standard deviation 24
Values 1.8e+02 1.4e+02
[34]
THLE CALM1
Mean 109
Standard deviation 13
Values 1e+02 1.2e+02
[35]
liver CALM1
Mean 127
Standard deviation 70
Values 2.1e+02 80 1.7e+02 57
[36]
ref_hepatocyte BCL2L1
Mean 26.8
Standard deviation 12
Values 16 44 34 23 16
[37]
HepG2 BCL2L1
Mean 260
Standard deviation 56
Values 3e+02 2.2e+02
[38]
HepG2.C3A BCL2L1
Mean 152
Standard deviation 4.3
Values 1.5e+02 1.5e+02
[39]
HuH.7 BCL2L1
Mean 283
Standard deviation 60
Values 3.1e+02 2.1e+02 3.2e+02
[40]
SNU475 BCL2L1
Mean 32.1
Standard deviation 4.1
Values 29 35
[41]
THLE BCL2L1
Mean 47
Standard deviation 4.7
Values 44 50
[42]
liver BCL2L1
Mean 21.6
Standard deviation 11
Values 31 9.8 31 14
[43]
ref_hepatocyte GOLGA7
Mean 21.8
Standard deviation 7.5
Values 22 21 34 14 18
[44]
HepG2 GOLGA7
Mean 17.3
Standard deviation 1.3
Values 16 18
[45]
HepG2.C3A GOLGA7
Mean 23.2
Standard deviation 3.3
Values 21 25
[46]
HuH.7 GOLGA7
Mean 36.9
Standard deviation 1.7
Values 36 36 39
[47]
SNU475 GOLGA7
Mean 13.7
Standard deviation 1.9
Values 15 12
[48]
THLE GOLGA7
Mean 19
Standard deviation 1.5
Values 20 18
[49]
liver GOLGA7
Mean 18.7
Standard deviation 14
Values 34 7.9 27 6.3
[50]
ref_hepatocyte FNTA
Mean 18.3
Standard deviation 3.8
Values 23 22 15 16 15
[51]
HepG2 FNTA
Mean 21.7
Standard deviation 0.34
Values 21 22
[52]
HepG2.C3A FNTA
Mean 37.7
Standard deviation 5.1
Values 41 34
[53]
HuH.7 FNTA
Mean 52.9
Standard deviation 10
Values 44 64 50
[54]
SNU475 FNTA
Mean 11
Standard deviation 2.7
Values 13 9
[55]
THLE FNTA
Mean 17.5
Standard deviation 1.6
Values 19 16
[56]
liver FNTA
Mean 13.9
Standard deviation 5.5
Values 18 10 19 8.1
[57]
ref_hepatocyte LYPLA1
Mean 18.3
Standard deviation 8
Values 19 28 15 7.1 23
[58]
HepG2 LYPLA1
Mean 42.9
Standard deviation 0.83
Values 42 43
[59]
HepG2.C3A LYPLA1
Mean 60.6
Standard deviation 8.8
Values 54 67
[60]
HuH.7 LYPLA1
Mean 30.3
Standard deviation 5.1
Values 34 25 32
[61]
SNU475 LYPLA1
Mean 37.5
Standard deviation 6.3
Values 42 33
[62]
THLE LYPLA1
Mean 37.7
Standard deviation 6.8
Values 33 43
[63]
liver LYPLA1
Mean 37.3
Standard deviation 14
Values 46 29 52 22
[64]
ref_hepatocyte NRAS
Mean 14.4
Standard deviation 13
Values 32 23 9.3 3.3 4.6
[65]
HepG2 NRAS
Mean 49.3
Standard deviation 10
Values 42 57
[66]
HepG2.C3A NRAS
Mean 59.2
Standard deviation 18
Values 47 72
[67]
HuH.7 NRAS
Mean 75.6
Standard deviation 9.1
Values 86 70 71
[68]
SNU475 NRAS
Mean 52.9
Standard deviation 9.2
Values 59 46
[69]
THLE NRAS
Mean 44
Standard deviation 8.9
Values 38 50
[70]
liver NRAS
Mean 17.2
Standard deviation 2.6
Values 14 21 18 16
[71]
ref_hepatocyte HRAS
Mean 11.6
Standard deviation 9
Values 4 27 11 7.4 8.8
[72]
HepG2 HRAS
Mean 12.7
Standard deviation 1.1
Values 14 12
[73]
HepG2.C3A HRAS
Mean 6.96
Standard deviation 1.3
Values 6 7.9
[74]
HuH.7 HRAS
Mean 3.85
Standard deviation 1.6
Values 3.6 2.4 5.6
[75]
SNU475 HRAS
Mean 11
Standard deviation 0.62
Values 11 11
[76]
THLE HRAS
Mean 10.7
Standard deviation 2.3
Values 9.1 12
[77]
liver HRAS
Mean 2.6
Standard deviation 1.6
Values 4.1 1.1 3.8 1.4
[78]
ref_hepatocyte ZDHHC9
Mean 9.68
Standard deviation 4
Values 4.8 8.5 13 14 7.6
[79]
HepG2 ZDHHC9
Mean 49.2
Standard deviation 12
Values 57 41
[80]
HepG2.C3A ZDHHC9
Mean 39.5
Standard deviation 10
Values 47 32
[81]
HuH.7 ZDHHC9
Mean 51.8
Standard deviation 6.7
Values 57 55 44
[82]
SNU475 ZDHHC9
Mean 14.9
Standard deviation 0.62
Values 14 15
[83]
THLE ZDHHC9
Mean 17.8
Standard deviation 0.24
Values 18 18
[84]
liver ZDHHC9
Mean 25.9
Standard deviation 13
Values 35 14 39 15
[85]
ref_hepatocyte KRAS
Mean 8.97
Standard deviation 7.9
Values 18 17 5.4 1.7 2.7
[86]
HepG2 KRAS
Mean 13.9
Standard deviation 3.1
Values 12 16
[87]
HepG2.C3A KRAS
Mean 12.2
Standard deviation 2.3
Values 11 14
[88]
HuH.7 KRAS
Mean 35.4
Standard deviation 4.8
Values 40 30 36
[89]
SNU475 KRAS
Mean 28.7
Standard deviation 5.5
Values 33 25
[90]
THLE KRAS
Mean 25.4
Standard deviation 1.5
Values 24 26
[91]
liver KRAS
Mean 20.4
Standard deviation 8.7
Values 33 16 19 14
[92]
ref_hepatocyte ARL2
Mean 8.87
Standard deviation 5.9
Values 18 2.1 9.3 7.6 7
[93]
HepG2 ARL2
Mean 16.2
Standard deviation 1.8
Values 17 15
[94]
HepG2.C3A ARL2
Mean 18.4
Standard deviation 4.3
Values 21 15
[95]
HuH.7 ARL2
Mean 3.12
Standard deviation 0.91
Values 3.1 2.2 4
[96]
SNU475 ARL2
Mean 11
Standard deviation 3.1
Values 13 8.8
[97]
THLE ARL2
Mean 14
Standard deviation 0.84
Values 15 13
[98]
liver ARL2
Mean 2.71
Standard deviation 2.3
Values 3.5 0.93 5.7 0.74
[99]
ref_hepatocyte ICMT
Mean 7.05
Standard deviation 4.6
Values 15 7 3.9 5.4 4
[100]
HepG2 ICMT
Mean 60.3
Standard deviation 7.3
Values 55 65
[101]
HepG2.C3A ICMT
Mean 69.6
Standard deviation 15
Values 59 80
[102]
HuH.7 ICMT
Mean 47.8
Standard deviation 18
Values 64 29 51
[103]
SNU475 ICMT
Mean 44.4
Standard deviation 3.5
Values 42 47
[104]
THLE ICMT
Mean 82.7
Standard deviation 11
Values 75 91
[105]
liver ICMT
Mean 18.7
Standard deviation 5
Values 12 21 20 23
[106]
ref_hepatocyte PDE6D
Mean 5.63
Standard deviation 1
Values 6.9 4.9 5.5 6.4 4.5
[107]
HepG2 PDE6D
Mean 5.67
Standard deviation 0.78
Values 5.1 6.2
[108]
HepG2.C3A PDE6D
Mean 2.85
Standard deviation 0.14
Values 2.8 2.9
[109]
HuH.7 PDE6D
Mean 8.16
Standard deviation 3.1
Values 9 4.8 11
[110]
SNU475 PDE6D
Mean 6.11
Standard deviation 0.048
Values 6.1 6.1
[111]
THLE PDE6D
Mean 8.53
Standard deviation 0.047
Values 8.6 8.5
[112]
liver PDE6D
Mean 2.84
Standard deviation 2
Values 3.5 1.6 5.3 0.91
[113]
ref_hepatocyte RCE1
Mean 3.01
Standard deviation 1.1
Values 4.3 2.6 4.1 2.4 1.7
[114]
HepG2 RCE1
Mean 11.8
Standard deviation 1.8
Values 13 11
[115]
HepG2.C3A RCE1
Mean 9.42
Standard deviation 1.5
Values 10 8.4
[116]
HuH.7 RCE1
Mean 30.2
Standard deviation 5.7
Values 30 25 36
[117]
SNU475 RCE1
Mean 8.98
Standard deviation 0.16
Values 8.9 9.1
[118]
THLE RCE1
Mean 6.65
Standard deviation 0.25
Values 6.5 6.8
[119]
liver RCE1
Mean 1.65
Standard deviation 0.34
Values 1.9 1.2 1.6 1.9
[120]
ref_hepatocyte FNTB
Mean 1
Standard deviation 1
Values 0.27 1.9 2.3 0.47 0.098
[121]
HepG2 FNTB
Mean 1.04
Standard deviation 0.28
Values 0.84 1.2
[122]
HepG2.C3A FNTB
Mean 0.772
Standard deviation 0.35
Values 0.52 1
[123]
HuH.7 FNTB
Mean 0.154
Standard deviation 0.051
Values 0.21 0.15 0.1
[124]
SNU475 FNTB
Mean 0.523
Standard deviation 0.24
Values 0.7 0.35
[125]
THLE FNTB
Mean 0.37
Standard deviation 0.15
Values 0.26 0.48
[126]
liver FNTB
Mean 0.291
Standard deviation 0.23
Values 0.33 0.071 0.59 0.17
[127]
ref_hepatocyte PRKCQ
Mean 0.0639
Standard deviation 0.072
Values 0 0.11 0 0.043 0.16
[128]
HepG2 PRKCQ
Mean 0.264
Standard deviation 0.11
Values 0.34 0.18
[129]
HepG2.C3A PRKCQ
Mean 0.0199
Standard deviation 0.013
Values 0.029 0.011
[130]
HuH.7 PRKCQ
Mean 0
Standard deviation 0
Values 0 0 0
[131]
SNU475 PRKCQ
Mean 0.513
Standard deviation 0.44
Values 0.2 0.83
[132]
THLE PRKCQ
Mean 1.63
Standard deviation 0.3
Values 1.8 1.4
[133]
liver PRKCQ
Mean 0.386
Standard deviation 0.17
Values 0.19 0.3 0.51 0.54
[134]
ref_hepatocyte PRKG2
Mean 0.00924
Standard deviation 0.021
Values 0 0 0.046 0 0
[135]
HepG2 PRKG2
Mean 0.153
Standard deviation 0.12
Values 0.24 0.064
[136]
HepG2.C3A PRKG2
Mean 0
Standard deviation 0
Values 0 0
[137]
HuH.7 PRKG2
Mean 0
Standard deviation 0
Values 0 0 0
[138]
SNU475 PRKG2
Mean 1.87
Standard deviation 0.4
Values 2.2 1.6
[139]
THLE PRKG2
Mean 0.0402
Standard deviation 0.048
Values 0.0059 0.074
[140]
liver PRKG2
Mean 0.054
Standard deviation 0.05
Values 0.024 0.1 0 0.093
[141]
ref_hepatocyte ABHD17C
Missing
[142]
HepG2 ABHD17C
Missing
[143]
HepG2.C3A ABHD17C
Missing
[144]
HuH.7 ABHD17C
Missing
[145]
SNU475 ABHD17C
Missing
[146]
THLE ABHD17C
Missing
[147]
liver ABHD17C
Missing
[148]
ref_hepatocyte USP17L2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[149]
HepG2 USP17L2
Mean 0
Standard deviation 0
Values 0 0
[150]
HepG2.C3A USP17L2
Mean 0
Standard deviation 0
Values 0 0
[151]
HuH.7 USP17L2
Mean 0
Standard deviation 0
Values 0 0 0
[152]
SNU475 USP17L2
Mean 0.0139
Standard deviation 0.02
Values 0.028 0
[153]
THLE USP17L2
Mean 0.00532
Standard deviation 0.0075
Values 0 0.011
[154]
liver USP17L2
Mean 0.0339
Standard deviation 0.027
Values 0 0.057 0.026 0.053
[155]
ref_hepatocyte ABHD17B
Missing
[156]
HepG2 ABHD17B
Missing
[157]
HepG2.C3A ABHD17B
Missing
[158]
HuH.7 ABHD17B
Missing
[159]
SNU475 ABHD17B
Missing
[160]
THLE ABHD17B
Missing
[161]
liver ABHD17B
Missing
[162]
ref_hepatocyte ABHD17A
Missing
[163]
HepG2 ABHD17A
Missing
[164]
HepG2.C3A ABHD17A
Missing
[165]
HuH.7 ABHD17A
Missing
[166]
SNU475 ABHD17A
Missing
[167]
THLE ABHD17A
Missing
[168]
liver ABHD17A
Missing