REACTOME_RAF_ACTIVATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 PHB Prohibitin [1] -0.23[2] -0.40[3] -1.03[4] -1.76[5] -1.52[6] -1.28[7]
2 YWHAB 14-3-3 protein beta/alpha [8] 0.73[9] 0.38[10] -0.40[11] 0.79[12] 0.46[13] -0.37[14]
3 PPP1CB Serine/threonine-protein phosphatase PP1-beta catalytic subunit [15] -0.55[16] -0.04[17] -0.01[18] 0.25[19] 0.30[20] 0.22[21]
4 CALM1 Calmodulin-1 [22] -0.23[23] -0.26[24] 0.15[25] 1.07[26] 0.58[27] 1.34[28]
5 MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 [29] -1.24[30] -1.63[31] -1.11[32] -1.05[33] -0.32[34] -1.47[35]
6 PPP2R1A Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform 0.49[36] 0.26[37] 0.12[38] 0.70[39] 0.25[40] -0.13[41]
7 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 [42] -0.25[43] -0.64[44] 0.17[45] -1.35[46] -0.64[47] -1.98[48]
8 PPP2CA Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform -0.04[49] 0.00[50] -0.69[51] 0.23[52] 0.57[53] -0.38[54]
9 PPP1CC Serine/threonine-protein phosphatase PP1-gamma catalytic subunit 0.37[55] 1.09[56] 1.26[57] -0.27[58] 0.06[59] -1.36[60]
10 PPP2CB Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform -0.70[61] -1.10[62] -1.08[63] -0.97[64] -0.84[65] -1.26[66]
11 RAF1 RAF proto-oncogene serine/threonine-protein kinase [67] -0.37[68] -0.03[69] 1.18[70] -0.70[71] 0.40[72] 0.82[73]
12 NRAS GTPase NRas [74] 0.32[75] 0.69[76] 1.04[77] 0.49[78] 0.29[79] -0.53[80]
13 PPP2R5A Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform -1.43[81] -0.60[82] 0.06[83] -0.76[84] -1.66[85] 0.36[86]
14 PPP2R5C Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform -0.61[87] 0.20[88] -0.16[89] 0.43[90] 0.47[91] -0.47[92]
15 ARAF Serine/threonine-protein kinase A-Raf [93] -0.76[94] -1.13[95] -0.92[96] -0.61[97] -0.34[98] 0.60[99]
16 PPP2R1B Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform 0.14[100] -0.44[101] -0.09[102] -0.24[103] -0.23[104] 2.65[105]
17 HRAS GTPase HRas [106] -1.32[107] -2.08[108] -2.93[109] -1.46[110] -1.44[111] -2.94[112]
18 MAP3K11 Mitogen-activated protein kinase kinase kinase 11 [113] 0.78[114] 0.66[115] 0.23[116] -0.37[117] -0.27[118] 0.18[119]
19 KRAS GTPase KRas [120] -0.82[121] -0.90[122] 0.64[123] 0.29[124] 0.18[125] 0.40[126]
20 MARK3 MAP/microtubule affinity-regulating kinase 3 [127] -0.38[128] -0.18[129] -0.25[130] 0.62[131] 0.54[132] -0.01[133]
21 PPP2R5D Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform 0.94[134] 0.64[135] 0.14[136] 0.78[137] 0.89[138] -0.55[139]
22 SHOC2 Leucine-rich repeat protein SHOC-2 [140] -1.06[141] 0.24[142] -0.22[143] -0.39[144] 0.13[145] 0.41[146]
23 CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta [147] -0.18[148] 0.07[149] 1.53[150] 0.16[151] -0.41[152] 1.13[153]
24 PPP2R5E Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform -0.19[154] -0.08[155] -0.60[156] 0.35[157] 0.37[158] -0.08[159]
25 SRC Proto-oncogene tyrosine-protein kinase Src [160] 2.72[161] 2.64[162] 1.58[163] 1.89[164] 1.29[165] -1.13[166]
26 MRAS Ras-related protein M-Ras [167] 1.44[168] -4.28[169] -3.17[170] -0.06[171] 0.49[172] -1.94[173]
27 BRAP BRCA1-associated protein [174] 0.05[175] 0.19[176] 0.21[177] 0.37[178] 0.71[179] 0.47[180]
28 CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 0.47[181] 1.62[182] 1.17[183] 1.17[184] 0.97[185] 0.68[186]
29 PPP2R5B Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform 0.47[187] 0.17[188] -0.53[189] -0.22[190] 1.17[191] -0.18[192]
30 BRAF Serine/threonine-protein kinase B-raf [193] -0.06[194] -0.39[195] 1.58[196] 0.23[197] 0.15[198] 1.58[199]
31 JAK2 Tyrosine-protein kinase JAK2 [200] -0.08[201] -0.15[202] -0.65[203] 0.25[204] 1.08[205] 2.43[206]
32 CAMK2B Calcium/calmodulin-dependent protein kinase type II subunit beta [207] -2.84[208] -4.23[209] -7.25[210] -3.37[211] -2.51[212] 0.87[213]
33 KSR1 Kinase suppressor of Ras 1 [214] 2.96[215] 2.60[216] -0.55[217] 1.53[218] 2.26[219] 0.45[220]
34 CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha [221] [222] [223] [224] [225] [226] [227]
[1]
ref_hepatocyte PHB
Mean 76
Standard deviation 15
Values 69 1e+02 70 78 62
[2]
HepG2 PHB
Mean 178
Standard deviation 2.8
Values 1.8e+02 1.8e+02
[3]
HepG2.C3A PHB
Mean 146
Standard deviation 41
Values 1.2e+02 1.8e+02
[4]
HuH.7 PHB
Mean 94.8
Standard deviation 36
Values 1e+02 55 1.2e+02
[5]
SNU475 PHB
Mean 58.5
Standard deviation 7.6
Values 53 64
[6]
THLE PHB
Mean 66.4
Standard deviation 7.6
Values 61 72
[7]
liver PHB
Mean 53.9
Standard deviation 28
Values 72 36 84 25
[8]
ref_hepatocyte YWHAB
Mean 42.6
Standard deviation 20
Values 74 47 41 28 22
[9]
HepG2 YWHAB
Mean 193
Standard deviation 37
Values 1.7e+02 2.2e+02
[10]
HepG2.C3A YWHAB
Mean 141
Standard deviation 27
Values 1.2e+02 1.6e+02
[11]
HuH.7 YWHAB
Mean 82.2
Standard deviation 26
Values 98 52 97
[12]
SNU475 YWHAB
Mean 193
Standard deviation 7
Values 2e+02 1.9e+02
[13]
THLE YWHAB
Mean 146
Standard deviation 23
Values 1.3e+02 1.6e+02
[14]
liver YWHAB
Mean 56.6
Standard deviation 26
Values 78 39 80 30
[15]
ref_hepatocyte PPP1CB
Mean 31.9
Standard deviation 30
Values 65 64 8.8 6.2 16
[16]
HepG2 PPP1CB
Mean 59.8
Standard deviation 14
Values 50 70
[17]
HepG2.C3A PPP1CB
Mean 78.8
Standard deviation 12
Values 71 87
[18]
HuH.7 PPP1CB
Mean 80.4
Standard deviation 9.9
Values 92 76 74
[19]
SNU475 PPP1CB
Mean 99.4
Standard deviation 25
Values 1.2e+02 82
[20]
THLE PPP1CB
Mean 98.3
Standard deviation 1.6
Values 99 97
[21]
liver PPP1CB
Mean 64.1
Standard deviation 7.2
Values 67 68 67 53
[22]
ref_hepatocyte CALM1
Mean 29.2
Standard deviation 11
Values 17 40 21 28 40
[23]
HepG2 CALM1
Mean 67.9
Standard deviation 4.3
Values 65 71
[24]
HepG2.C3A CALM1
Mean 62
Standard deviation 16
Values 51 73
[25]
HuH.7 CALM1
Mean 81.9
Standard deviation 15
Values 90 64 92
[26]
SNU475 CALM1
Mean 160
Standard deviation 24
Values 1.8e+02 1.4e+02
[27]
THLE CALM1
Mean 109
Standard deviation 13
Values 1e+02 1.2e+02
[28]
liver CALM1
Mean 127
Standard deviation 70
Values 2.1e+02 80 1.7e+02 57
[29]
ref_hepatocyte MAP2K1
Mean 28.1
Standard deviation 8.6
Values 27 39 32 15 27
[30]
HepG2 MAP2K1
Mean 32.6
Standard deviation 3.7
Values 35 30
[31]
HepG2.C3A MAP2K1
Mean 23.1
Standard deviation 0.39
Values 23 23
[32]
HuH.7 MAP2K1
Mean 33.2
Standard deviation 6.4
Values 33 27 40
[33]
SNU475 MAP2K1
Mean 35.5
Standard deviation 5.2
Values 32 39
[34]
THLE MAP2K1
Mean 56.5
Standard deviation 3.6
Values 54 59
[35]
liver MAP2K1
Mean 17.5
Standard deviation 8
Values 28 11 18 12
[36]
ref_hepatocyte PPP2R1A
Mean 27.9
Standard deviation 5.4
Values 23 30 23 36 28
[37]
HepG2 PPP2R1A
Mean 107
Standard deviation 6.5
Values 1.1e+02 1e+02
[38]
HepG2.C3A PPP2R1A
Mean 84.7
Standard deviation 12
Values 93 76
[39]
HuH.7 PPP2R1A
Mean 77.2
Standard deviation 6.8
Values 84 70 78
[40]
SNU475 PPP2R1A
Mean 118
Standard deviation 14
Values 1.3e+02 1.1e+02
[41]
THLE PPP2R1A
Mean 83.3
Standard deviation 16
Values 72 94
[42]
liver PPP2R1A
Mean 43.9
Standard deviation 17
Values 51 30 65 30
[43]
ref_hepatocyte MAP2K2
Mean 27.7
Standard deviation 8.5
Values 22 20 28 42 26
[44]
HepG2 MAP2K2
Mean 63.6
Standard deviation 21
Values 79 48
[45]
HepG2.C3A MAP2K2
Mean 45.2
Standard deviation 14
Values 55 36
[46]
HuH.7 MAP2K2
Mean 79.3
Standard deviation 9.5
Values 87 82 69
[47]
SNU475 MAP2K2
Mean 28.4
Standard deviation 0.16
Values 28 28
[48]
THLE MAP2K2
Mean 44.5
Standard deviation 0.75
Values 44 45
[49]
liver MAP2K2
Mean 12.1
Standard deviation 3
Values 17 11 9.8 11
[50]
ref_hepatocyte PPP2CA
Mean 27.3
Standard deviation 6.4
Values 27 38 22 24 25
[51]
HepG2 PPP2CA
Mean 72.8
Standard deviation 15
Values 62 83
[52]
HepG2.C3A PPP2CA
Mean 69.2
Standard deviation 19
Values 55 83
[53]
HuH.7 PPP2CA
Mean 42.8
Standard deviation 4.9
Values 43 38 48
[54]
SNU475 PPP2CA
Mean 83.9
Standard deviation 4.1
Values 81 87
[55]
THLE PPP2CA
Mean 102
Standard deviation 13
Values 92 1.1e+02
[56]
liver PPP2CA
Mean 36.1
Standard deviation 13
Values 49 27 46 23
[57]
ref_hepatocyte PPP1CC
Mean 27
Standard deviation 18
Values 56 31 20 14 14
[58]
HepG2 PPP1CC
Mean 95.3
Standard deviation 20
Values 81 1.1e+02
[59]
HepG2.C3A PPP1CC
Mean 146
Standard deviation 2.8
Values 1.5e+02 1.4e+02
[60]
HuH.7 PPP1CC
Mean 164
Standard deviation 10
Values 1.8e+02 1.6e+02 1.6e+02
[61]
SNU475 PPP1CC
Mean 58.5
Standard deviation 7.8
Values 53 64
[62]
THLE PPP1CC
Mean 70.4
Standard deviation 7.7
Values 65 76
[63]
liver PPP1CC
Mean 18.1
Standard deviation 3.3
Values 23 17 15 18
[64]
ref_hepatocyte PPP2CB
Mean 25.5
Standard deviation 11
Values 15 43 27 17 26
[65]
HepG2 PPP2CB
Mean 43
Standard deviation 1.5
Values 44 42
[66]
HepG2.C3A PPP2CB
Mean 30.2
Standard deviation 0.78
Values 31 30
[67]
HuH.7 PPP2CB
Mean 30.6
Standard deviation 2.8
Values 28 34 30
[68]
SNU475 PPP2CB
Mean 34.2
Standard deviation 0.1
Values 34 34
[69]
THLE PPP2CB
Mean 35.7
Standard deviation 2.6
Values 37 34
[70]
liver PPP2CB
Mean 18.3
Standard deviation 7.2
Values 28 14 19 12
[71]
ref_hepatocyte RAF1
Mean 15.5
Standard deviation 5.7
Values 6 14 20 20 17
[72]
HepG2 RAF1
Mean 32.7
Standard deviation 5.2
Values 29 36
[73]
HepG2.C3A RAF1
Mean 38.6
Standard deviation 2.8
Values 41 37
[74]
HuH.7 RAF1
Mean 89
Standard deviation 4.2
Values 85 93 89
[75]
SNU475 RAF1
Mean 25
Standard deviation 4.6
Values 22 28
[76]
THLE RAF1
Mean 50.9
Standard deviation 5.2
Values 47 55
[77]
liver RAF1
Mean 47
Standard deviation 3.6
Values 51 42 49 46
[78]
ref_hepatocyte NRAS
Mean 14.4
Standard deviation 13
Values 32 23 9.3 3.3 4.6
[79]
HepG2 NRAS
Mean 49.3
Standard deviation 10
Values 42 57
[80]
HepG2.C3A NRAS
Mean 59.2
Standard deviation 18
Values 47 72
[81]
HuH.7 NRAS
Mean 75.6
Standard deviation 9.1
Values 86 70 71
[82]
SNU475 NRAS
Mean 52.9
Standard deviation 9.2
Values 59 46
[83]
THLE NRAS
Mean 44
Standard deviation 8.9
Values 38 50
[84]
liver NRAS
Mean 17.2
Standard deviation 2.6
Values 14 21 18 16
[85]
ref_hepatocyte PPP2R5A
Mean 14.2
Standard deviation 11
Values 8.7 5.8 6.2 21 30
[86]
HepG2 PPP2R5A
Mean 14.4
Standard deviation 0.58
Values 14 15
[87]
HepG2.C3A PPP2R5A
Mean 23.8
Standard deviation 5
Values 27 20
[88]
HuH.7 PPP2R5A
Mean 37.7
Standard deviation 14
Values 28 54 31
[89]
SNU475 PPP2R5A
Mean 21.9
Standard deviation 3
Values 24 20
[90]
THLE PPP2R5A
Mean 11.3
Standard deviation 0.33
Values 12 11
[91]
liver PPP2R5A
Mean 31.4
Standard deviation 5.3
Values 33 37 24 32
[92]
ref_hepatocyte PPP2R5C
Mean 14.1
Standard deviation 2.7
Values 15 17 10 13 15
[93]
HepG2 PPP2R5C
Mean 25.2
Standard deviation 5.7
Values 21 29
[94]
HepG2.C3A PPP2R5C
Mean 41.3
Standard deviation 0.87
Values 41 42
[95]
HuH.7 PPP2R5C
Mean 32.2
Standard deviation 4.1
Values 31 37 29
[96]
SNU475 PPP2R5C
Mean 49.7
Standard deviation 5.7
Values 54 46
[97]
THLE PPP2R5C
Mean 48.8
Standard deviation 6.3
Values 44 53
[98]
liver PPP2R5C
Mean 17.5
Standard deviation 1.8
Values 18 20 16 16
[99]
ref_hepatocyte ARAF
Mean 12.3
Standard deviation 8
Values 4.1 4 13 21 19
[100]
HepG2 ARAF
Mean 19.8
Standard deviation 1.6
Values 21 19
[101]
HepG2.C3A ARAF
Mean 14.3
Standard deviation 2.2
Values 16 13
[102]
HuH.7 ARAF
Mean 16.5
Standard deviation 1.9
Values 18 14 17
[103]
SNU475 ARAF
Mean 21.1
Standard deviation 1.4
Values 22 20
[104]
THLE ARAF
Mean 24.2
Standard deviation 1.6
Values 23 25
[105]
liver ARAF
Mean 32.1
Standard deviation 23
Values 50 11 54 13
[106]
ref_hepatocyte PPP2R1B
Mean 12
Standard deviation 3.3
Values 7 14 11 15 13
[107]
HepG2 PPP2R1B
Mean 36.3
Standard deviation 12
Values 27 45
[108]
HepG2.C3A PPP2R1B
Mean 22.5
Standard deviation 5.6
Values 19 26
[109]
HuH.7 PPP2R1B
Mean 28.7
Standard deviation 4.1
Values 32 30 24
[110]
SNU475 PPP2R1B
Mean 26.6
Standard deviation 1.2
Values 26 27
[111]
THLE PPP2R1B
Mean 25.6
Standard deviation 5.7
Values 22 30
[112]
liver PPP2R1B
Mean 130
Standard deviation 78
Values 52 1.6e+02 82 2.2e+02
[113]
ref_hepatocyte HRAS
Mean 11.6
Standard deviation 9
Values 4 27 11 7.4 8.8
[114]
HepG2 HRAS
Mean 12.7
Standard deviation 1.1
Values 14 12
[115]
HepG2.C3A HRAS
Mean 6.96
Standard deviation 1.3
Values 6 7.9
[116]
HuH.7 HRAS
Mean 3.85
Standard deviation 1.6
Values 3.6 2.4 5.6
[117]
SNU475 HRAS
Mean 11
Standard deviation 0.62
Values 11 11
[118]
THLE HRAS
Mean 10.7
Standard deviation 2.3
Values 9.1 12
[119]
liver HRAS
Mean 2.6
Standard deviation 1.6
Values 4.1 1.1 3.8 1.4
[120]
ref_hepatocyte MAP3K11
Mean 10.8
Standard deviation 3.8
Values 16 7.7 6.1 13 12
[121]
HepG2 MAP3K11
Mean 50.5
Standard deviation 6.9
Values 46 55
[122]
HepG2.C3A MAP3K11
Mean 43.3
Standard deviation 11
Values 51 35
[123]
HuH.7 MAP3K11
Mean 32
Standard deviation 5.2
Values 38 28 30
[124]
SNU475 MAP3K11
Mean 21.9
Standard deviation 1.7
Values 23 21
[125]
THLE MAP3K11
Mean 22.3
Standard deviation 1.7
Values 21 23
[126]
liver MAP3K11
Mean 21
Standard deviation 5.1
Values 24 19 15 26
[127]
ref_hepatocyte KRAS
Mean 8.97
Standard deviation 7.9
Values 18 17 5.4 1.7 2.7
[128]
HepG2 KRAS
Mean 13.9
Standard deviation 3.1
Values 12 16
[129]
HepG2.C3A KRAS
Mean 12.2
Standard deviation 2.3
Values 11 14
[130]
HuH.7 KRAS
Mean 35.4
Standard deviation 4.8
Values 40 30 36
[131]
SNU475 KRAS
Mean 28.7
Standard deviation 5.5
Values 33 25
[132]
THLE KRAS
Mean 25.4
Standard deviation 1.5
Values 24 26
[133]
liver KRAS
Mean 20.4
Standard deviation 8.7
Values 33 16 19 14
[134]
ref_hepatocyte MARK3
Mean 8.81
Standard deviation 4
Values 6.9 13 14 6.1 4.9
[135]
HepG2 MARK3
Mean 18.5
Standard deviation 2.2
Values 17 20
[136]
HepG2.C3A MARK3
Mean 19.8
Standard deviation 0.88
Values 20 19
[137]
HuH.7 MARK3
Mean 18.8
Standard deviation 1.9
Values 18 17 21
[138]
SNU475 MARK3
Mean 35.5
Standard deviation 3.7
Values 33 38
[139]
THLE MARK3
Mean 32
Standard deviation 0.32
Values 32 32
[140]
liver MARK3
Mean 15.1
Standard deviation 6.7
Values 11 22 8.1 20
[141]
ref_hepatocyte PPP2R5D
Mean 7.67
Standard deviation 1.8
Values 11 7.4 6.7 6.6 6.7
[142]
HepG2 PPP2R5D
Mean 40.3
Standard deviation 5.9
Values 36 44
[143]
HepG2.C3A PPP2R5D
Mean 30.4
Standard deviation 4.1
Values 27 33
[144]
HuH.7 PPP2R5D
Mean 21.5
Standard deviation 4.4
Values 26 17 22
[145]
SNU475 PPP2R5D
Mean 34.4
Standard deviation 4.8
Values 38 31
[146]
THLE PPP2R5D
Mean 35.6
Standard deviation 5.6
Values 32 40
[147]
liver PPP2R5D
Mean 9.05
Standard deviation 4.1
Values 11 5.8 14 5.4
[148]
ref_hepatocyte SHOC2
Mean 7.37
Standard deviation 5.7
Values 12 15 2.7 3.2 3.8
[149]
HepG2 SHOC2
Mean 9.65
Standard deviation 4.5
Values 6.5 13
[150]
HepG2.C3A SHOC2
Mean 22.1
Standard deviation 2.6
Values 20 24
[151]
HuH.7 SHOC2
Mean 16.1
Standard deviation 3.7
Values 15 20 13
[152]
SNU475 SHOC2
Mean 14.8
Standard deviation 0.43
Values 15 14
[153]
THLE SHOC2
Mean 20.2
Standard deviation 1.2
Values 21 19
[154]
liver SHOC2
Mean 16.9
Standard deviation 2.1
Values 15 20 16 17
[155]
ref_hepatocyte CAMK2D
Mean 6.27
Standard deviation 4.6
Values 12 11 1.6 2.7 4.7
[156]
HepG2 CAMK2D
Mean 15.2
Standard deviation 5.9
Values 11 19
[157]
HepG2.C3A CAMK2D
Mean 16.7
Standard deviation 1.9
Values 15 18
[158]
HuH.7 CAMK2D
Mean 46.1
Standard deviation 5.5
Values 51 47 40
[159]
SNU475 CAMK2D
Mean 18.4
Standard deviation 4.5
Values 22 15
[160]
THLE CAMK2D
Mean 11.8
Standard deviation 1.2
Values 13 11
[161]
liver CAMK2D
Mean 23.7
Standard deviation 6.1
Values 33 21 22 19
[162]
ref_hepatocyte PPP2R5E
Mean 5.64
Standard deviation 2
Values 6.5 7.7 6.9 3.9 3.2
[163]
HepG2 PPP2R5E
Mean 13.5
Standard deviation 2.7
Values 12 15
[164]
HepG2.C3A PPP2R5E
Mean 13.6
Standard deviation 2.9
Values 11 16
[165]
HuH.7 PPP2R5E
Mean 9.42
Standard deviation 2.1
Values 12 9.4 7.3
[166]
SNU475 PPP2R5E
Mean 18.8
Standard deviation 1.2
Values 20 18
[167]
THLE PPP2R5E
Mean 18.2
Standard deviation 0.7
Values 18 19
[168]
liver PPP2R5E
Mean 9.17
Standard deviation 1.5
Values 11 9.6 9.4 7
[169]
ref_hepatocyte SRC
Mean 3.67
Standard deviation 3.6
Values 9.6 4.7 2.2 0.77 1.2
[170]
HepG2 SRC
Mean 66
Standard deviation 21
Values 81 51
[171]
HepG2.C3A SRC
Mean 58.1
Standard deviation 18
Values 71 45
[172]
HuH.7 SRC
Mean 27.9
Standard deviation 2
Values 28 29 26
[173]
SNU475 SRC
Mean 35.6
Standard deviation 3.5
Values 38 33
[174]
THLE SRC
Mean 22.5
Standard deviation 2.7
Values 21 24
[175]
liver SRC
Mean 2.9
Standard deviation 1
Values 4.1 2.5 1.7 3.2
[176]
ref_hepatocyte MRAS
Mean 3.26
Standard deviation 5.7
Values 13 2.1 0.42 0.41 0.15
[177]
HepG2 MRAS
Mean 24.2
Standard deviation 5.3
Values 21 28
[178]
HepG2.C3A MRAS
Mean 0.426
Standard deviation 0.066
Values 0.38 0.47
[179]
HuH.7 MRAS
Mean 0.918
Standard deviation 0.11
Values 0.94 1 0.8
[180]
SNU475 MRAS
Mean 8.2
Standard deviation 1.9
Values 9.5 6.9
[181]
THLE MRAS
Mean 11.4
Standard deviation 0.24
Values 11 12
[182]
liver MRAS
Mean 1.46
Standard deviation 0.22
Values 1.2 1.6 1.7 1.4
[183]
ref_hepatocyte BRAP
Mean 3.21
Standard deviation 1.1
Values 4.5 3 3.9 2.8 1.8
[184]
HepG2 BRAP
Mean 9.06
Standard deviation 1.2
Values 8.2 9.9
[185]
HepG2.C3A BRAP
Mean 9.29
Standard deviation 2
Values 7.9 11
[186]
HuH.7 BRAP
Mean 9.44
Standard deviation 0.52
Values 9.4 8.9 10
[187]
SNU475 BRAP
Mean 10.8
Standard deviation 1.1
Values 10 12
[188]
THLE BRAP
Mean 13.2
Standard deviation 0.98
Values 12 14
[189]
liver BRAP
Mean 7.63
Standard deviation 0.83
Values 7.1 8.6 8 6.8
[190]
ref_hepatocyte CAMK2G
Mean 2.9
Standard deviation 1.2
Values 2.8 2.3 4.9 1.9 2.6
[191]
HepG2 CAMK2G
Mean 11
Standard deviation 0.61
Values 11 11
[192]
HepG2.C3A CAMK2G
Mean 22.6
Standard deviation 3.2
Values 25 20
[193]
HuH.7 CAMK2G
Mean 16.6
Standard deviation 0.56
Values 16 17 17
[194]
SNU475 CAMK2G
Mean 17.1
Standard deviation 1.1
Values 18 16
[195]
THLE CAMK2G
Mean 14.2
Standard deviation 0.22
Values 14 14
[196]
liver CAMK2G
Mean 7.98
Standard deviation 1
Values 9.1 7 7.2 8.6
[197]
ref_hepatocyte PPP2R5B
Mean 2.1
Standard deviation 0.85
Values 1.5 2.2 2.4 3.3 1.2
[198]
HepG2 PPP2R5B
Mean 7.95
Standard deviation 0.71
Values 7.4 8.5
[199]
HepG2.C3A PPP2R5B
Mean 6.01
Standard deviation 3.4
Values 8.4 3.6
[200]
HuH.7 PPP2R5B
Mean 3.69
Standard deviation 1.6
Values 2.4 5.5 3.2
[201]
SNU475 PPP2R5B
Mean 4.72
Standard deviation 0.053
Values 4.8 4.7
[202]
THLE PPP2R5B
Mean 11.9
Standard deviation 2.7
Values 14 10
[203]
liver PPP2R5B
Mean 3.19
Standard deviation 1.1
Values 3.5 2 4.5 2.8
[204]
ref_hepatocyte BRAF
Mean 1.07
Standard deviation 0.72
Values 0.56 1.2 2.3 0.67 0.67
[205]
HepG2 BRAF
Mean 2.8
Standard deviation 0.62
Values 2.4 3.2
[206]
HepG2.C3A BRAF
Mean 2.07
Standard deviation 0.66
Values 1.6 2.5
[207]
HuH.7 BRAF
Mean 8.12
Standard deviation 5.8
Values 6.4 15 3.4
[208]
SNU475 BRAF
Mean 3.28
Standard deviation 0.16
Values 3.2 3.4
[209]
THLE BRAF
Mean 2.97
Standard deviation 0.38
Values 2.7 3.2
[210]
liver BRAF
Mean 5.48
Standard deviation 2.9
Values 3.1 8 2.9 7.9
[211]
ref_hepatocyte JAK2
Mean 0.762
Standard deviation 0.48
Values 1.3 1.3 0.62 0.18 0.5
[212]
HepG2 JAK2
Mean 1.97
Standard deviation 1.3
Values 1 2.9
[213]
HepG2.C3A JAK2
Mean 1.75
Standard deviation 0.67
Values 1.3 2.2
[214]
HuH.7 JAK2
Mean 1.23
Standard deviation 0.34
Values 1.2 1.6 0.9
[215]
SNU475 JAK2
Mean 2.37
Standard deviation 0.1
Values 2.3 2.4
[216]
THLE JAK2
Mean 4.02
Standard deviation 0.77
Values 4.6 3.5
[217]
liver JAK2
Mean 7.06
Standard deviation 3.8
Values 4.7 11 2.9 9.8
[218]
ref_hepatocyte CAMK2B
Mean 0.643
Standard deviation 0.6
Values 0 1.1 0 0.9 1.3
[219]
HepG2 CAMK2B
Mean 0.245
Standard deviation 0.067
Values 0.29 0.2
[220]
HepG2.C3A CAMK2B
Mean 0.0871
Standard deviation 0.013
Values 0.078 0.097
[221]
HuH.7 CAMK2B
Mean 0.0107
Standard deviation 0.0051
Values 0.016 0.0064 0.0094
[222]
SNU475 CAMK2B
Mean 0.162
Standard deviation 0.072
Values 0.21 0.11
[223]
THLE CAMK2B
Mean 0.283
Standard deviation 0.15
Values 0.39 0.18
[224]
liver CAMK2B
Mean 2.02
Standard deviation 0.9
Values 1.5 2.2 3.2 1.2
[225]
ref_hepatocyte KSR1
Mean 0.387
Standard deviation 0.39
Values 1 0.34 0.38 0.06 0.11
[226]
HepG2 KSR1
Mean 8.21
Standard deviation 0.63
Values 8.7 7.8
[227]
HepG2.C3A KSR1
Mean 5.95
Standard deviation 0.11
Values 6 5.9
[228]
HuH.7 KSR1
Mean 0.672
Standard deviation 0.25
Values 0.6 0.95 0.47
[229]
SNU475 KSR1
Mean 2.94
Standard deviation 0.81
Values 2.4 3.5
[230]
THLE KSR1
Mean 4.65
Standard deviation 0.57
Values 4.2 5
[231]
liver KSR1
Mean 0.913
Standard deviation 0.48
Values 0.49 1.4 0.51 1.2
[232]
ref_hepatocyte CAMK2A
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[233]
HepG2 CAMK2A
Mean 0.0787
Standard deviation 0.022
Values 0.063 0.094
[234]
HepG2.C3A CAMK2A
Mean 0.0468
Standard deviation 0.025
Values 0.029 0.064
[235]
HuH.7 CAMK2A
Mean 0.0232
Standard deviation 0.016
Values 0.041 0.019 0.0094
[236]
SNU475 CAMK2A
Mean 1.25
Standard deviation 0.78
Values 1.8 0.69
[237]
THLE CAMK2A
Mean 0.231
Standard deviation 0.034
Values 0.21 0.26
[238]
liver CAMK2A
Mean 0.0104
Standard deviation 0.014
Values 0 0.029 0 0.013