REACTOME_RAC1_GTPASE_CYCLE |
Return to index |
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Order |
Gene |
Description |
ref_hepatocyte |
HepG2 |
HepG2.C3A |
HuH.7 |
SNU475 |
THLE |
liver |
1 |
ITGB1 |
Integrin beta-1 |
[1] |
-0.43[2] |
-0.41[3] |
-0.42[4] |
0.52[5] |
0.76[6] |
-0.36[7] |
2 |
CDC42 |
Cell division control protein 42 homolog |
[8] |
-1.49[9] |
-0.77[10] |
-1.92[11] |
-1.47[12] |
-2.04[13] |
-2.60[14] |
3 |
RAB7A |
Ras-related protein Rab-7a |
[15] |
-1.46[16] |
-1.98[17] |
-1.93[18] |
-2.01[19] |
-1.32[20] |
-1.83[21] |
4 |
ARHGDIA |
Rho GDP-dissociation inhibitor 1 |
[22] |
-1.18[23] |
-1.86[24] |
-2.76[25] |
-1.94[26] |
-1.41[27] |
-2.35[28] |
5 |
BRK1 |
Protein BRICK1 |
[29] |
-2.04[30] |
-2.25[31] |
-1.83[32] |
-3.20[33] |
-2.10[34] |
-2.66[35] |
6 |
RAC1 |
Ras-related C3 botulinum toxin substrate 1 |
[36] |
-1.05[37] |
-1.39[38] |
-0.82[39] |
-0.92[40] |
-0.78[41] |
-1.49[42] |
7 |
LAMTOR1 |
Ragulator complex protein LAMTOR1 |
[43] |
-1.28[44] |
-2.03[45] |
-2.27[46] |
-2.02[47] |
-1.90[48] |
-1.82[49] |
8 |
CDC42EP1 |
Cdc42 effector protein 1 |
[50] |
-0.51[51] |
-1.32[52] |
-1.12[53] |
-3.51[54] |
-1.58[55] |
-1.12[56] |
9 |
KTN1 |
Kinectin |
[57] |
-1.38[58] |
0.80[59] |
0.30[60] |
0.97[61] |
-0.33[62] |
0.40[63] |
10 |
CAV1 |
Caveolin-1 |
[64] |
-7.50[65] |
-10.33[66] |
-4.20[67] |
0.44[68] |
-0.76[69] |
-2.52[70] |
11 |
VAMP3 |
Vesicle-associated membrane protein 3 |
[71] |
-0.43[72] |
0.11[73] |
-0.84[74] |
-0.22[75] |
-0.51[76] |
-1.54[77] |
12 |
YKT6 |
Synaptobrevin homolog YKT6 |
[78] |
-0.27[79] |
-0.65[80] |
-1.33[81] |
-0.43[82] |
-0.50[83] |
-2.43[84] |
13 |
SNAP23 |
Synaptosomal-associated protein 23 |
[85] |
-0.70[86] |
-0.66[87] |
-1.54[88] |
-0.99[89] |
-1.02[90] |
-1.15[91] |
14 |
FERMT2 |
Fermitin family homolog 2 |
[92] |
-1.31[93] |
-1.46[94] |
-1.68[95] |
0.30[96] |
-0.46[97] |
-0.20[98] |
15 |
ESYT1 |
Extended synaptotagmin-1 |
[99] |
0.49[100] |
-0.14[101] |
-0.39[102] |
-0.21[103] |
0.12[104] |
0.54[105] |
16 |
EMD |
Emerin |
[106] |
-1.75[107] |
-1.81[108] |
-2.23[109] |
-1.36[110] |
-1.21[111] |
-2.58[112] |
17 |
IQGAP2 |
Ras GTPase-activating-like protein IQGAP2 |
[113] |
-1.48[114] |
0.74[115] |
0.77[116] |
-5.44[117] |
-7.78[118] |
2.08[119] |
18 |
TFRC |
Transferrin receptor protein 1 |
[120] |
2.78[121] |
2.27[122] |
2.25[123] |
0.51[124] |
2.15[125] |
1.06[126] |
19 |
CYBA |
Cytochrome b-245 light chain |
[127] |
0.83[128] |
0.86[129] |
-0.38[130] |
-0.73[131] |
-0.68[132] |
-1.94[133] |
20 |
RALBP1 |
RalA-binding protein 1 |
[134] |
-0.76[135] |
-0.34[136] |
0.53[137] |
-0.12[138] |
-0.56[139] |
-0.55[140] |
21 |
GNA13 |
Guanine nucleotide-binding protein subunit alpha-13 |
[141] |
-0.54[142] |
-0.38[143] |
-0.05[144] |
0.25[145] |
-0.76[146] |
0.02[147] |
22 |
ABI1 |
Abl interactor 1 |
[148] |
-1.44[149] |
-0.48[150] |
-0.56[151] |
-0.24[152] |
-1.03[153] |
-0.63[154] |
23 |
NCF2 |
Neutrophil cytosol factor 2 |
[155] |
-2.47[156] |
-5.18[157] |
-9.08[158] |
-3.82[159] |
-10.29[160] |
-2.94[161] |
24 |
NCKAP1 |
Nck-associated protein 1 |
[162] |
0.50[163] |
1.50[164] |
1.46[165] |
1.86[166] |
1.67[167] |
0.84[168] |
25 |
FARP1 |
FERM, ARHGEF and pleckstrin domain-containing protein 1 |
[169] |
1.58[170] |
1.54[171] |
-0.16[172] |
-1.34[173] |
-1.71[174] |
0.96[175] |
26 |
PAK2 |
Serine/threonine-protein kinase PAK 2 |
[176] |
0.79[177] |
0.53[178] |
0.68[179] |
-0.18[180] |
0.52[181] |
0.84[182] |
27 |
LBR |
Lamin-B receptor |
[183] |
0.08[184] |
0.78[185] |
1.49[186] |
0.40[187] |
-0.40[188] |
0.26[189] |
28 |
CYFIP1 |
Cytoplasmic FMR1-interacting protein 1 |
[190] |
0.61[191] |
0.20[192] |
-0.32[193] |
0.19[194] |
0.09[195] |
0.80[196] |
29 |
PKN1 |
Serine/threonine-protein kinase N1 |
[197] |
1.36[198] |
0.32[199] |
1.23[200] |
-0.07[201] |
0.77[202] |
-1.07[203] |
30 |
TMPO |
Lamina-associated polypeptide 2, isoform alpha |
[204] |
0.29[205] |
1.06[206] |
1.18[207] |
1.22[208] |
1.27[209] |
0.28[210] |
31 |
BAIAP2L1 |
Brain-specific angiogenesis
inhibitor 1-associated protein 2-like protein 1 |
0.28[211] |
-0.31[212] |
-0.02[213] |
-1.61[214] |
-1.07[215] |
-0.96[216] |
32 |
CDC42EP4 |
Cdc42 effector protein 4 |
[217] |
0.21[218] |
-0.31[219] |
-0.22[220] |
-0.56[221] |
-0.99[222] |
-0.02[223] |
33 |
WASL |
Neural Wiskott-Aldrich syndrome protein |
[224] |
-1.14[225] |
-0.07[226] |
0.18[227] |
0.16[228] |
-0.52[229] |
0.61[230] |
34 |
VAV2 |
Guanine nucleotide exchange factor VAV2 |
[231] |
0.64[232] |
0.89[233] |
0.23[234] |
-1.47[235] |
-0.90[236] |
-0.01[237] |
35 |
BAIAP2 |
Brain-specific angiogenesis inhibitor 1-associated protein 2 |
[238] |
-0.81[239] |
-1.44[240] |
-2.36[241] |
-0.68[242] |
-0.59[243] |
0.53[244] |
36 |
ARHGAP17 |
Rho GTPase-activating protein 17 |
[245] |
-0.17[246] |
0.00[247] |
-0.83[248] |
-0.57[249] |
-0.85[250] |
-1.29[251] |
37 |
EPHA2 |
Ephrin type-A receptor 2 |
[252] |
1.59[253] |
1.80[254] |
-0.52[255] |
0.00[256] |
0.71[257] |
-1.30[258] |
38 |
PIK3R1 |
Phosphatidylinositol 3-kinase regulatory subunit alpha |
[259] |
-1.13[260] |
-1.02[261] |
-0.07[262] |
1.13[263] |
0.78[264] |
2.48[265] |
39 |
ARAP1 |
Arf-GAP with Rho-GAP domain, ANK
repeat and PH domain-containing protein 1 |
1.49[266] |
0.61[267] |
-0.02[268] |
0.46[269] |
0.12[270] |
0.92[271] |
40 |
SOS1 |
Son of sevenless homolog 1 |
[272] |
-0.76[273] |
0.77[274] |
0.13[275] |
-0.09[276] |
-0.71[277] |
0.02[278] |
41 |
ARHGDIB |
Rho GDP-dissociation inhibitor 2 |
[279] |
-5.71[280] |
-5.91[281] |
-7.01[282] |
-2.54[283] |
-1.96[284] |
0.21[285] |
42 |
SLC1A5 |
Neutral amino acid transporter B(0) |
[286] |
2.96[287] |
2.15[288] |
1.93[289] |
2.26[290] |
1.61[291] |
-2.46[292] |
43 |
WASF2 |
Wiskott-Aldrich syndrome protein family member 2 |
[293] |
1.35[294] |
0.59[295] |
1.45[296] |
1.99[297] |
1.44[298] |
1.04[299] |
44 |
ARHGEF5 |
Rho guanine nucleotide exchange factor 5 |
[300] |
-4.67[301] |
-3.43[302] |
-3.35[303] |
-3.23[304] |
-3.00[305] |
-2.93[306] |
45 |
ALS2 |
Alsin |
[307] |
-0.18[308] |
0.31[309] |
0.82[310] |
0.02[311] |
0.04[312] |
1.23[313] |
46 |
PIK3R2 |
Phosphatidylinositol 3-kinase regulatory subunit beta |
[314] |
1.21[315] |
1.43[316] |
1.90[317] |
-0.23[318] |
0.48[319] |
-0.81[320] |
47 |
ARHGAP12 |
Rho GTPase-activating protein 12 |
[321] |
0.39[322] |
1.46[323] |
0.95[324] |
0.64[325] |
-0.49[326] |
1.15[327] |
48 |
GIT2 |
ARF GTPase-activating protein GIT2 |
[328] |
-0.34[329] |
0.17[330] |
-0.40[331] |
0.22[332] |
0.18[333] |
0.54[334] |
49 |
IQGAP1 |
Ras GTPase-activating-like protein IQGAP1 |
[335] |
1.19[336] |
0.74[337] |
1.00[338] |
3.03[339] |
3.03[340] |
1.50[341] |
50 |
PAK4 |
Serine/threonine-protein kinase PAK 4 |
[342] |
0.23[343] |
0.27[344] |
0.82[345] |
0.08[346] |
-0.04[347] |
-0.85[348] |
51 |
WIPF2 |
WAS/WASL-interacting protein family member 2 |
[349] |
1.02[350] |
-0.40[351] |
0.55[352] |
0.34[353] |
-0.06[354] |
-0.18[355] |
52 |
TAOK3 |
Serine/threonine-protein kinase TAO3 |
[356] |
-1.09[357] |
-0.42[358] |
0.89[359] |
-0.28[360] |
0.04[361] |
0.72[362] |
53 |
VRK2 |
Serine/threonine-protein kinase VRK2 |
[363] |
-1.72[364] |
-0.59[365] |
-1.91[366] |
-1.14[367] |
-1.35[368] |
-1.12[369] |
54 |
ARHGAP21 |
Rho GTPase-activating protein 21 |
[370] |
-0.10[371] |
0.88[372] |
1.62[373] |
2.18[374] |
1.08[375] |
1.21[376] |
55 |
ARHGAP35 |
Rho GTPase-activating protein 35 |
[377] |
1.68[378] |
1.81[379] |
2.21[380] |
1.80[381] |
1.53[382] |
2.74[383] |
56 |
DLC1 |
Rho GTPase-activating protein 7 |
[384] |
1.65[385] |
1.30[386] |
0.47[387] |
-0.07[388] |
0.58[389] |
1.88[390] |
57 |
ARHGAP1 |
Rho GTPase-activating protein 1 |
[391] |
1.12[392] |
0.72[393] |
1.07[394] |
-0.44[395] |
-0.08[396] |
1.11[397] |
58 |
NGEF |
Ephexin-1 |
[398] |
-0.31[399] |
0.58[400] |
0.61[401] |
-5.96[402] |
-3.20[403] |
0.29[404] |
59 |
FAM13A |
Protein FAM13A |
[405] |
-1.93[406] |
-0.21[407] |
1.58[408] |
-1.28[409] |
-1.01[410] |
1.33[411] |
60 |
DOCK7 |
Dedicator of cytokinesis protein 7 |
[412] |
0.87[413] |
1.48[414] |
0.84[415] |
0.44[416] |
0.22[417] |
0.96[418] |
61 |
TRIO |
Triple functional domain protein |
[419] |
1.34[420] |
1.07[421] |
1.17[422] |
1.67[423] |
2.71[424] |
2.23[425] |
62 |
ARHGAP5 |
Rho GTPase-activating protein 5 |
[426] |
1.75[427] |
1.35[428] |
4.51[429] |
1.63[430] |
1.37[431] |
2.62[432] |
63 |
ARHGAP29 |
Rho GTPase-activating protein 29 |
[433] |
-0.09[434] |
-1.39[435] |
1.34[436] |
1.75[437] |
-2.11[438] |
1.79[439] |
64 |
CHN2 |
Beta-chimaerin |
[440] |
-0.44[441] |
0.02[442] |
0.26[443] |
-2.09[444] |
-3.76[445] |
0.98[446] |
65 |
BCR |
Breakpoint cluster region protein |
[447] |
1.57[448] |
0.81[449] |
0.92[450] |
0.08[451] |
0.61[452] |
1.18[453] |
66 |
ECT2 |
Protein ECT2 |
[454] |
0.02[455] |
1.71[456] |
2.57[457] |
1.19[458] |
1.94[459] |
-1.40[460] |
67 |
PLEKHG3 |
Pleckstrin homology domain-containing family G member 3 |
[461] |
-0.87[462] |
-0.64[463] |
-0.03[464] |
-0.68[465] |
-1.33[466] |
0.28[467] |
68 |
PKN2 |
Serine/threonine-protein kinase N2 |
[468] |
0.30[469] |
1.60[470] |
1.56[471] |
1.21[472] |
1.20[473] |
1.32[474] |
69 |
GIT1 |
ARF GTPase-activating protein GIT1 |
[475] |
1.31[476] |
1.18[477] |
0.45[478] |
1.02[479] |
0.88[480] |
-0.99[481] |
70 |
SWAP70 |
Switch-associated protein 70 |
[482] |
0.15[483] |
-0.40[484] |
0.44[485] |
0.83[486] |
0.78[487] |
0.26[488] |
71 |
MCAM |
Cell surface glycoprotein MUC18 |
[489] |
2.75[490] |
-0.01[491] |
-2.17[492] |
3.34[493] |
0.69[494] |
-0.29[495] |
72 |
ARHGAP27 |
Rho GTPase-activating protein 27 |
[496] |
0.63[497] |
0.92[498] |
-0.52[499] |
-0.79[500] |
-1.55[501] |
-0.98[502] |
73 |
MYO9B |
Unconventional myosin-IXb |
[503] |
1.64[504] |
1.21[505] |
2.68[506] |
1.36[507] |
1.67[508] |
1.84[509] |
74 |
ARHGEF7 |
Rho guanine nucleotide exchange factor 7 |
[510] |
0.96[511] |
0.95[512] |
0.66[513] |
0.88[514] |
0.78[515] |
1.83[516] |
75 |
ARHGEF18 |
Rho guanine nucleotide exchange factor 18 |
[517] |
2.02[518] |
1.10[519] |
1.77[520] |
0.39[521] |
0.88[522] |
1.07[523] |
76 |
DOCK1 |
Dedicator of cytokinesis protein 1 |
[524] |
1.32[525] |
1.85[526] |
1.70[527] |
-3.59[528] |
1.37[529] |
2.00[530] |
77 |
JAG1 |
Protein jagged-1 |
[531] |
4.12[532] |
2.70[533] |
2.02[534] |
0.58[535] |
-0.62[536] |
0.53[537] |
78 |
SOS2 |
Son of sevenless homolog 2 |
[538] |
-0.69[539] |
0.44[540] |
-0.48[541] |
0.75[542] |
0.77[543] |
1.32[544] |
79 |
NISCH |
Nischarin |
[545] |
1.77[546] |
1.94[547] |
0.89[548] |
1.10[549] |
2.13[550] |
2.05[551] |
80 |
LEMD3 |
Inner nuclear membrane protein Man1 |
[552] |
0.24[553] |
1.21[554] |
1.01[555] |
0.28[556] |
0.91[557] |
0.94[558] |
81 |
ABI2 |
Abl interactor 2 |
[559] |
1.01[560] |
1.73[561] |
1.89[562] |
1.78[563] |
1.96[564] |
1.08[565] |
82 |
PAK1 |
Serine/threonine-protein kinase PAK 1 |
[566] |
-0.67[567] |
-1.44[568] |
0.83[569] |
-2.80[570] |
1.14[571] |
-0.25[572] |
83 |
RACGAP1 |
Rac GTPase-activating protein 1 |
[573] |
1.44[574] |
1.90[575] |
2.00[576] |
2.24[577] |
2.94[578] |
-1.23[579] |
84 |
DEPDC1B |
DEP domain-containing protein 1B |
[580] |
0.52[581] |
2.05[582] |
2.12[583] |
0.07[584] |
0.76[585] |
-3.51[586] |
85 |
SPATA13 |
Spermatogenesis-associated protein 13 |
[587] |
0.07[588] |
0.60[589] |
0.85[590] |
0.41[591] |
-0.40[592] |
3.44[593] |
86 |
CDC42BPA |
Serine/threonine-protein kinase MRCK alpha |
[594] |
0.11[595] |
1.11[596] |
1.12[597] |
2.66[598] |
1.49[599] |
3.25[600] |
87 |
PLD1 |
Phospholipase D1 |
[601] |
1.76[602] |
2.47[603] |
2.81[604] |
0.11[605] |
0.86[606] |
1.54[607] |
88 |
PLD2 |
Phospholipase D2 |
[608] |
0.29[609] |
0.82[610] |
0.56[611] |
-0.18[612] |
-0.17[613] |
0.38[614] |
89 |
CYFIP2 |
Cytoplasmic FMR1-interacting protein 2 |
[615] |
2.46[616] |
2.11[617] |
-5.50[618] |
-0.83[619] |
-1.56[620] |
2.50[621] |
90 |
SRGAP2 |
SLIT-ROBO Rho GTPase-activating protein 2 |
[622] |
1.08[623] |
1.16[624] |
0.73[625] |
1.47[626] |
1.66[627] |
-0.12[628] |
91 |
ARHGAP10 |
Rho GTPase-activating protein 10 |
[629] |
-3.33[630] |
-5.95[631] |
-2.26[632] |
-0.70[633] |
0.73[634] |
-0.28[635] |
92 |
DIAPH3 |
Protein diaphanous homolog 3 |
[636] |
-0.70[637] |
0.38[638] |
0.72[639] |
0.62[640] |
1.64[641] |
-3.11[642] |
93 |
NOXA1 |
NADPH oxidase activator 1 |
[643] |
-3.02[644] |
-1.26[645] |
-2.44[646] |
-3.33[647] |
-4.39[648] |
-1.50[649] |
94 |
PIK3CA |
Phosphatidylinositol
4,5-bisphosphate 3-kinase catalytic subunit alpha isoform |
-1.04[650] |
0.59[651] |
0.64[652] |
0.19[653] |
0.55[654] |
1.39[655] |
95 |
FAM13B |
Protein FAM13B |
[656] |
-0.03[657] |
0.73[658] |
-0.49[659] |
1.31[660] |
0.92[661] |
1.29[662] |
96 |
ARHGEF11 |
Rho guanine nucleotide exchange factor 11 |
[663] |
1.38[664] |
1.49[665] |
1.04[666] |
2.33[667] |
1.78[668] |
2.07[669] |
97 |
GMIP |
GEM-interacting protein |
[670] |
0.05[671] |
-0.87[672] |
0.19[673] |
-0.24[674] |
-0.17[675] |
-0.86[676] |
98 |
NCF1 |
Neutrophil cytosol factor 1 |
[677] |
-7.82[678] |
-9.88[679] |
[680] |
[681] |
-10.08[682] |
-3.32[683] |
99 |
WASF1 |
Wiskott-Aldrich syndrome protein family member 1 |
[684] |
0.68[685] |
0.36[686] |
1.55[687] |
0.22[688] |
1.02[689] |
-0.13[690] |
100 |
ARHGAP42 |
Rho GTPase-activating protein 42 |
[691] |
-1.94[692] |
-5.50[693] |
-1.76[694] |
0.80[695] |
-0.42[696] |
1.25[697] |
101 |
DOCK4 |
Dedicator of cytokinesis protein 4 |
[698] |
1.94[699] |
1.57[700] |
1.64[701] |
1.38[702] |
-0.14[703] |
3.14[704] |
102 |
DOCK5 |
Dedicator of cytokinesis protein 5 |
[705] |
1.35[706] |
1.90[707] |
1.32[708] |
0.77[709] |
1.59[710] |
3.31[711] |
103 |
DOCK6 |
Dedicator of cytokinesis protein 6 |
[712] |
2.58[713] |
2.39[714] |
2.21[715] |
-0.05[716] |
-0.10[717] |
1.81[718] |
104 |
CYBB |
Cytochrome b-245 heavy chain |
[719] |
[720] |
[721] |
-11.03[722] |
-5.41[723] |
-10.81[724] |
2.53[725] |
105 |
DOCK9 |
Dedicator of cytokinesis protein 9 |
[726] |
-0.84[727] |
-3.46[728] |
-0.28[729] |
1.12[730] |
0.74[731] |
2.27[732] |
106 |
PLEKHG6 |
Pleckstrin homology domain-containing family G member 6 |
[733] |
0.61[734] |
1.76[735] |
1.57[736] |
-2.14[737] |
-3.31[738] |
-0.40[739] |
107 |
WASF3 |
Wiskott-Aldrich syndrome protein family member 3 |
[740] |
0.90[741] |
0.84[742] |
1.90[743] |
1.48[744] |
0.42[745] |
0.39[746] |
108 |
MCF2L |
Guanine nucleotide exchange factor DBS |
[747] |
1.61[748] |
1.80[749] |
-0.54[750] |
-5.56[751] |
-8.62[752] |
0.99[753] |
109 |
PARD6A |
Partitioning defective 6 homolog alpha |
[754] |
-1.07[755] |
-1.11[756] |
-4.26[757] |
-2.13[758] |
-2.98[759] |
-1.66[760] |
110 |
ABL2 |
Abelson tyrosine-protein kinase 2 |
[761] |
1.41[762] |
1.43[763] |
2.23[764] |
2.94[765] |
3.30[766] |
2.40[767] |
111 |
FARP2 |
FERM, ARHGEF and pleckstrin domain-containing protein 2 |
[768] |
0.79[769] |
1.14[770] |
-0.35[771] |
0.22[772] |
0.46[773] |
1.75[774] |
112 |
DEF6 |
Differentially expressed in FDCP 6 homolog |
[775] |
1.19[776] |
1.46[777] |
-0.26[778] |
1.05[779] |
-3.86[780] |
-1.06[781] |
113 |
MPP7 |
MAGUK p55 subfamily member 7 |
[782] |
-0.57[783] |
2.00[784] |
-2.69[785] |
2.39[786] |
-2.56[787] |
0.61[788] |
114 |
ARHGAP26 |
Rho GTPase-activating protein 26 |
[789] |
2.00[790] |
2.34[791] |
0.71[792] |
0.86[793] |
0.99[794] |
1.76[795] |
115 |
RASGRF2 |
Ras-specific guanine nucleotide-releasing factor 2 |
[796] |
3.18[797] |
2.43[798] |
-2.03[799] |
-3.87[800] |
-1.49[801] |
0.00[802] |
116 |
KALRN |
Kalirin |
[803] |
0.69[804] |
2.23[805] |
1.58[806] |
0.97[807] |
-3.54[808] |
3.04[809] |
117 |
ABR |
Active breakpoint cluster region-related protein |
[810] |
3.29[811] |
2.86[812] |
2.25[813] |
2.49[814] |
3.36[815] |
1.32[816] |
118 |
WAS |
Wiskott-Aldrich syndrome protein |
[817] |
-6.38[818] |
-5.83[819] |
-2.54[820] |
-4.45[821] |
-5.34[822] |
-0.93[823] |
119 |
ARAP2 |
Arf-GAP with Rho-GAP domain, ANK
repeat and PH domain-containing protein 2 |
-2.11[824] |
0.92[825] |
-8.57[826] |
-2.24[827] |
0.96[828] |
3.22[829] |
120 |
FMNL1 |
Formin-like protein 1 |
[830] |
1.22[831] |
-0.90[832] |
-2.47[833] |
2.45[834] |
2.21[835] |
-0.01[836] |
121 |
VANGL1 |
Vang-like protein 1 |
[837] |
2.31[838] |
1.74[839] |
1.02[840] |
3.27[841] |
3.10[842] |
2.17[843] |
122 |
NCF4 |
Neutrophil cytosol factor 4 |
[844] |
-6.43[845] |
-8.75[846] |
[847] |
-8.99[848] |
[849] |
0.39[850] |
123 |
SH3BP1 |
SH3 domain-binding protein 1 |
[851] |
2.49[852] |
3.07[853] |
2.56[854] |
-1.11[855] |
2.29[856] |
-0.79[857] |
124 |
ARHGAP30 |
Rho GTPase-activating protein 30 |
[858] |
-2.97[859] |
-3.87[860] |
-1.81[861] |
-3.39[862] |
-3.51[863] |
1.42[864] |
125 |
TIAM1 |
T-lymphoma invasion and metastasis-inducing protein 1 |
[865] |
-5.36[866] |
-2.69[867] |
-8.03[868] |
-2.30[869] |
-0.09[870] |
2.82[871] |
126 |
ARHGAP4 |
Rho GTPase-activating protein 4 |
[872] |
-2.51[873] |
1.08[874] |
-3.10[875] |
-2.50[876] |
-3.70[877] |
1.53[878] |
127 |
VAV3 |
Guanine nucleotide exchange factor VAV3 |
[879] |
1.15[880] |
-0.57[881] |
1.46[882] |
2.75[883] |
-3.08[884] |
0.83[885] |
128 |
WIPF1 |
WAS/WASL-interacting protein family member 1 |
[886] |
-4.61[887] |
-8.27[888] |
1.93[889] |
-0.08[890] |
2.69[891] |
2.01[892] |
129 |
CHN1 |
N-chimaerin |
[893] |
0.12[894] |
0.72[895] |
0.19[896] |
1.97[897] |
3.17[898] |
-0.64[899] |
130 |
DOCK8 |
Dedicator of cytokinesis protein 8 |
[900] |
-1.82[901] |
-3.65[902] |
1.61[903] |
-3.50[904] |
-4.86[905] |
3.12[906] |
131 |
DOCK10 |
Dedicator of cytokinesis protein 10 |
[907] |
-6.41[908] |
-7.22[909] |
-6.09[910] |
3.92[911] |
1.59[912] |
2.82[913] |
132 |
OPHN1 |
Oligophrenin-1 |
[914] |
1.05[915] |
1.07[916] |
1.50[917] |
2.25[918] |
0.97[919] |
4.22[920] |
133 |
NCKAP1L |
Nck-associated protein 1-like |
[921] |
[922] |
[923] |
[924] |
-4.94[925] |
-6.25[926] |
2.57[927] |
134 |
VAV1 |
Proto-oncogene vav |
[928] |
-9.16[929] |
-4.33[930] |
-6.19[931] |
-7.03[932] |
-8.13[933] |
0.66[934] |
135 |
ARHGEF6 |
Rho guanine nucleotide exchange factor 6 |
[935] |
-6.68[936] |
-4.43[937] |
-5.19[938] |
2.29[939] |
0.97[940] |
2.62[941] |
136 |
WIPF3 |
WAS/WASL-interacting protein family member 3 |
[942] |
-2.00[943] |
-5.21[944] |
1.79[945] |
-1.54[946] |
-3.80[947] |
-1.06[948] |
137 |
ARHGEF19 |
Rho guanine nucleotide exchange factor 19 |
[949] |
0.83[950] |
2.25[951] |
0.62[952] |
0.81[953] |
1.87[954] |
0.35[955] |
138 |
ARHGAP24 |
Rho GTPase-activating protein 24 |
[956] |
-4.88[957] |
-5.28[958] |
0.60[959] |
1.10[960] |
3.34[961] |
2.26[962] |
139 |
ARHGAP9 |
Rho GTPase-activating protein 9 |
[963] |
-2.29[964] |
-2.90[965] |
-1.12[966] |
-4.78[967] |
-4.45[968] |
1.26[969] |
140 |
PLEKHG2 |
Pleckstrin homology domain-containing family G member 2 |
[970] |
3.05[971] |
2.48[972] |
3.19[973] |
3.79[974] |
2.98[975] |
0.99[976] |
141 |
PIK3R3 |
Phosphatidylinositol 3-kinase regulatory subunit gamma |
[977] |
1.06[978] |
1.07[979] |
1.77[980] |
2.23[981] |
1.40[982] |
2.16[983] |
142 |
ARHGEF25 |
Rho guanine nucleotide exchange factor 25 |
[984] |
2.36[985] |
3.55[986] |
2.59[987] |
0.45[988] |
2.22[989] |
-0.58[990] |
143 |
PREX1 |
Phosphatidylinositol
3,4,5-trisphosphate-dependent Rac exchanger 1 protein |
-1.08[991] |
-6.90[992] |
-4.74[993] |
4.17[994] |
2.67[995] |
3.68[996] |
144 |
IQGAP3 |
Ras GTPase-activating-like protein IQGAP3 |
[997] |
3.11[998] |
4.09[999] |
3.41[1000] |
3.82[1001] |
5.16[1002] |
0.43[1003] |
145 |
ARHGAP32 |
Rho GTPase-activating protein 32 |
[1004] |
3.07[1005] |
2.86[1006] |
1.78[1007] |
3.53[1008] |
2.26[1009] |
3.65[1010] |
146 |
ARHGAP25 |
Rho GTPase-activating protein 25 |
[1011] |
-8.77[1012] |
[1013] |
-2.74[1014] |
-2.77[1015] |
-1.16[1016] |
2.36[1017] |
147 |
SYDE2 |
Rho GTPase-activating protein SYDE2 |
[1018] |
-0.35[1019] |
0.65[1020] |
1.17[1021] |
0.81[1022] |
-0.76[1023] |
3.40[1024] |
148 |
PLEKHG1 |
Pleckstrin homology domain-containing family G member 1 |
[1025] |
-2.59[1026] |
-2.95[1027] |
3.58[1028] |
-1.97[1029] |
-2.25[1030] |
3.57[1031] |
149 |
ARAP3 |
Arf-GAP with Rho-GAP domain, ANK
repeat and PH domain-containing protein 3 |
0.17[1032] |
-3.91[1033] |
-1.72[1034] |
1.70[1035] |
3.41[1036] |
2.20[1037] |
150 |
ARHGAP15 |
Rho GTPase-activating protein 15 |
[1038] |
[1039] |
-7.55[1040] |
-6.16[1041] |
-3.75[1042] |
-8.75[1043] |
2.32[1044] |
151 |
ARHGEF10 |
Rho guanine nucleotide exchange factor 10 |
[1045] |
-4.67[1046] |
-4.20[1047] |
-5.30[1048] |
2.17[1049] |
3.20[1050] |
1.35[1051] |
152 |
SRGAP1 |
SLIT-ROBO Rho GTPase-activating protein 1 |
[1052] |
2.89[1053] |
2.35[1054] |
2.56[1055] |
2.52[1056] |
3.06[1057] |
1.84[1058] |
153 |
NOXO1 |
NADPH oxidase organizer 1 |
[1059] |
-1.16[1060] |
0.14[1061] |
-2.69[1062] |
-3.44[1063] |
-3.05[1064] |
-1.24[1065] |
154 |
DOCK2 |
Dedicator of cytokinesis protein 2 |
[1066] |
-5.11[1067] |
[1068] |
-7.42[1069] |
1.55[1070] |
0.59[1071] |
3.81[1072] |
155 |
ARHGAP39 |
Rho GTPase-activating protein 39 |
[1073] |
2.29[1074] |
2.15[1075] |
2.00[1076] |
1.79[1077] |
0.24[1078] |
0.23[1079] |
156 |
ARHGAP33 |
Rho GTPase-activating protein 33 |
[1080] |
-0.10[1081] |
2.26[1082] |
1.13[1083] |
1.21[1084] |
1.61[1085] |
0.16[1086] |
157 |
AMIGO2 |
Amphoterin-induced protein 2 |
[1087] |
-1.97[1088] |
-1.80[1089] |
3.93[1090] |
5.20[1091] |
4.73[1092] |
2.50[1093] |
158 |
ARHGAP31 |
Rho GTPase-activating protein 31 |
[1094] |
-3.62[1095] |
-2.81[1096] |
-2.58[1097] |
4.00[1098] |
3.86[1099] |
3.65[1100] |
159 |
PLEKHG4 |
Puratrophin-1 |
[1101] |
3.75[1102] |
4.62[1103] |
0.29[1104] |
3.34[1105] |
2.00[1106] |
-0.62[1107] |
160 |
CIT |
Citron Rho-interacting kinase |
[1108] |
3.59[1109] |
4.07[1110] |
4.86[1111] |
4.36[1112] |
5.14[1113] |
1.53[1114] |
161 |
DOCK11 |
Dedicator of cytokinesis protein 11 |
[1115] |
-1.01[1116] |
-4.66[1117] |
2.66[1118] |
4.08[1119] |
4.06[1120] |
3.41[1121] |
162 |
TAGAP |
T-cell activation Rho GTPase-activating protein |
[1122] |
-6.48[1123] |
-6.88[1124] |
-6.56[1125] |
[1126] |
-3.30[1127] |
1.31[1128] |
163 |
ARHGAP20 |
Rho GTPase-activating protein 20 |
[1129] |
-5.66[1130] |
[1131] |
[1132] |
3.29[1133] |
2.60[1134] |
2.51[1135] |
164 |
ARHGAP22 |
Rho GTPase-activating protein 22 |
[1136] |
-2.43[1137] |
-3.37[1138] |
-2.20[1139] |
0.78[1140] |
3.11[1141] |
-0.23[1142] |
165 |
FGD5 |
FYVE, RhoGEF and PH domain-containing protein 5 |
[1143] |
-2.39[1144] |
[1145] |
-6.56[1146] |
-5.41[1147] |
-5.23[1148] |
4.43[1149] |
166 |
ARHGAP44 |
Rho GTPase-activating protein 44 |
[1150] |
3.05[1151] |
0.27[1152] |
1.06[1153] |
4.52[1154] |
2.98[1155] |
1.33[1156] |
167 |
TIAM2 |
T-lymphoma invasion and metastasis-inducing protein 2 |
[1157] |
3.25[1158] |
2.65[1159] |
3.94[1160] |
3.60[1161] |
1.63[1162] |
-0.55[1163] |
168 |
ARHGAP23 |
Rho GTPase-activating protein 23 |
[1164] |
2.84[1165] |
-1.44[1166] |
-1.06[1167] |
6.44[1168] |
6.38[1169] |
3.47[1170] |
169 |
PAK3 |
Serine/threonine-protein kinase PAK 3 |
[1171] |
-7.07[1172] |
[1173] |
[1174] |
-2.54[1175] |
-0.66[1176] |
0.26[1177] |
170 |
ARHGEF15 |
Rho guanine nucleotide exchange factor 15 |
[1178] |
[1179] |
-5.62[1180] |
[1181] |
-4.86[1182] |
[1183] |
3.44[1184] |
171 |
PAK6 |
Serine/threonine-protein kinase PAK 6 |
[1185] |
-2.33[1186] |
[1187] |
0.25[1188] |
1.26[1189] |
0.53[1190] |
-1.60[1191] |
172 |
DOCK3 |
Dedicator of cytokinesis protein 3 |
[1192] |
0.06[1193] |
-0.04[1194] |
0.72[1195] |
4.09[1196] |
0.69[1197] |
2.50[1198] |
173 |
PREX2 |
Phosphatidylinositol
3,4,5-trisphosphate-dependent Rac exchanger 2 protein |
-4.07[1199] |
-4.01[1200] |
2.96[1201] |
1.66[1202] |
[1203] |
6.39[1204] |
174 |
SRGAP3 |
SLIT-ROBO Rho GTPase-activating protein 3 |
[1205] |
2.38[1206] |
1.97[1207] |
6.70[1208] |
0.20[1209] |
1.68[1210] |
4.04[1211] |
175 |
NHS |
Nance-Horan syndrome protein |
[1212] |
-1.78[1213] |
[1214] |
-2.50[1215] |
3.94[1216] |
3.12[1217] |
2.48[1218] |
176 |
NOX1 |
NADPH oxidase 1 |
[1219] |
-0.31[1220] |
-1.08[1221] |
3.94[1222] |
-1.00[1223] |
0.53[1224] |
0.31[1225] |
177 |
ARHGEF4 |
Rho guanine nucleotide exchange factor 4 |
[1226] |
1.66[1227] |
-3.81[1228] |
-4.87[1229] |
4.01[1230] |
4.48[1231] |
1.44[1232] |
178 |
ARHGAP45 |
Rho GTPase-activating protein 45 |
[1233] |
[1234] |
[1235] |
[1236] |
[1237] |
[1238] |
[1239] |
179 |
ERBIN |
Erbin |
[1240] |
[1241] |
[1242] |
[1243] |
[1244] |
[1245] |
[1246] |
180 |
ARHGEF39 |
Rho guanine nucleotide exchange factor 39 |
[1247] |
[1248] |
[1249] |
[1250] |
[1251] |
[1252] |
[1253] |
181 |
PAK5 |
Serine/threonine-protein kinase PAK 5 |
[1254] |
[1255] |
[1256] |
[1257] |
[1258] |
[1259] |
[1260] |
182 |
GARRE1 |
|
[1261] |
[1262] |
[1263] |
[1264] |
[1265] |
[1266] |
[1267] |
183 |
NOX3 |
NADPH oxidase 3 |
[1268] |
[1269] |
[1270] |
[1271] |
[1272] |
[1273] |
[1274] |
184 |
MCF2 |
Proto-oncogene DBL |
[1275] |
[1276] |
[1277] |
[1278] |
[1279] |
[1280] |
[1281] |
|
|
|
|
|
|
|
|
|
|